Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway

Journal of Cell Biology

Volumn 164, Issue 1, 2004, Pages 123-131

  Lee, Jiunn Tay ^b   Xu, Jan ^a   Lee, Jin Moo ^a   Ku, Grace ^a   Han, Xianlin ^a   Yang, Ding I ^a   Chen, Shawei ^a   Hsu, Chung Y ^a,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Alzheimer's disease; Apoptosis; Cell death; Oxidative stress; White matter

Indexed keywords

3 O METHYLSPHINGOMYELIN; ACIDIC SPHINGOMYELINASE; AMYLOID BETA PROTEIN; ANTISENSE OLIGONUCLEOTIDE; CERAMIDE; GLUTATHIONE; MONOETHANOLAMINE OLEATE; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; KNOCKOUT GENE; NERVE CELL DEGENERATION; NONHUMAN; OLIGODENDROGLIA; OXIDATION; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SENILE PLAQUE; WHITE MATTER;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; CELL DEATH; CELLS, CULTURED; CERAMIDES; ETHANOLAMINES; GLUTATHIONE; NERVE DEGENERATION; OLIGODENDROGLIA; OXIDATIVE STRESS; RATS; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELINS; UP-REGULATION;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0347122965     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200307017     Document Type: Article

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