Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: Potential role in disease pathogenesis

Journal of Neurochemistry

Volumn 82, Issue 4, 2002, Pages 809-818

  Han, Xianlin ^a   Holtzman, David M ^a   McKeel Jr , Daniel W ^a   Kelley, John ^a   Morris, John C ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Ceramide elevation; Galactocerebroside; Galactocerebroside sulfotransferase; Mass spectrometry; Sulfatide deficiency

Indexed keywords

CERAMIDE; GALACTOSYLCERAMIDE; MYELIN; SPHINGOLIPID; SULFATIDE; SULFOTRANSFERASE;

ALZHEIMER DISEASE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; GRAY MATTER; HUMAN; HUMAN TISSUE; MASS SPECTROMETRY; NEUROCHEMISTRY; PATHOGENESIS; PRIORITY JOURNAL; WHITE MATTER;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BRAIN; BRAIN CHEMISTRY; CERAMIDES; DEMENTIA; DISEASE PROGRESSION; GALACTOSYLCERAMIDES; HUMANS; NEUROPSYCHOLOGICAL TESTS; SEVERITY OF ILLNESS INDEX; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPHINGOMYELINS; SULFOGLYCOSPHINGOLIPIDS; SULFOTRANSFERASES;

EID: 0036677303     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00997.x     Document Type: Article

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