Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking

American Journal of Pathology

Volumn 184, Issue 7, 2014, Pages 2066-2081

  Barbero Camps, Elisabet ^a,b   Fernández, Anna ^a,b   Baulies, Anna ^a,b   Martinez, Laura ^a,b   Fernández Checa, Jose C ^a,b,c   Colell, Anna ^a,b  

^a INST D INVESTIGACIONS B   (Spain)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 PHENYLBUTYRIC ACID; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CHOLESTEROL; GLUTATHIONE; GLUTATHIONE ETHYL ESTER; MEMBRANE PROTEIN; PRESENILIN 1; STEROIDOGENIC ACUTE REGULATORY PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; SREBF2 PROTEIN, MOUSE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN MITOCHONDRION; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FEMALE; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MALE; MOUSE; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UNFOLDED PROTEIN RESPONSE; ANIMAL; DISEASE MODEL; ENDOPLASMIC RETICULUM; METABOLISM; MITOCHONDRION; PATHOLOGY; TRANSGENIC MOUSE; TUMOR CELL LINE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CELL LINE, TUMOR; CHOLESTEROL; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GLUTATHIONE; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; MALE; MEMBRANE PROTEINS; MICE, TRANSGENIC; MITOCHONDRIA; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

EID: 84903197320     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.03.014     Document Type: Article

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