An ER-mitochondria tethering complex revealed by a synthetic biology screen

Science

Volumn 325, Issue 5939, 2009, Pages 477-481

  Kornmann, Benoît ^a   Currie, Erin ^a,e   Collins, Sean R ^a,b,f   Schuldiner, Maya ^c   Nunnari, Jodi ^d   Weissman, Jonathan S ^a,b   Walter, Peter ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^f STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; MITOCHONDRIAL PROTEIN; PHOSPHOLIPID; PROTEIN MDM10; PROTEIN MDM12; PROTEIN MDM34; PROTEIN MMM1; UNCLASSIFIED DRUG;

CALCIUM; EUKARYOTE; GENE EXPRESSION; GENOME; MITOCHONDRION; MUTATION; PHOSPHOLIPID; PROTEIN;

ARTICLE; CALCIUM SIGNALING; CELL JUNCTION; CELL MUTANT; CELL ORGANELLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE INTERACTION; GENE MAPPING; MITOCHONDRION; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE;

ANIMALS; CALCIUM SIGNALING; ENDOPLASMIC RETICULUM; MEMBRANE PROTEINS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PHOSPHOLIPIDS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA;

EID: 67749122635     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1175088     Document Type: Article

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33. We thank all members of the Walter lab for their support; N. Krogan, S. Wang, and N. Bajwa for their work creating the genetic interaction maps; and J. Shaw and K. Okamoto for their kind gift of Plasmids and discussions. This work was supported by NIH. B.K. is a fellow of the Swiss National Science Foundation; M.S. is supported by a Human Frontiers Science Program Career Development Award; and P.W and J.S.W, are investigators at the Howard Hughes Medical Institute.