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Volumn , Issue , 2006, Pages 57-93

Polymer micelles as drug carriers

Author keywords

[No Author keywords available]

Indexed keywords

DRUG CARRIER; POLYMER MICELLES;

EID: 84967566793     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1142/9781860949074_0005     Document Type: Chapter
Times cited : (86)

References (199)
  • 1
    • 0001587817 scopus 로고
    • The relationship existing between chemical constitution, distribution, and pharmacological action
    • Himmelweite F, Marquardt M and Dale H (eds.). Pergamon, Elmsford, New York
    • Ehrlich P (1956) The relationship existing between chemical constitution, distribution, and pharmacological action, in Himmelweite F, Marquardt M and Dale H (eds.) The Collected Papers of Paul Ehrlich. Pergamon, Elmsford, New York, Vol. 1, pp. 596-618.
    • (1956) The Collected Papers of Paul Ehrlich , vol.1 , pp. 596-618
    • Ehrlich, P.1
  • 2
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski CA, Lombardo F, Dominy BW and Feeney PJ (2001) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Del Rev 46:3-26.
    • (2001) Adv Drug Del Rev , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 4
    • 0034890106 scopus 로고    scopus 로고
    • Optimization of metabolic stability as a goal of modern drug design
    • Thompson TN (2001) Optimization of metabolic stability as a goal of modern drug design. Med Res Rev 21:412-449.
    • (2001) Med Res Rev , vol.21 , pp. 412-449
    • Thompson, T.N.1
  • 5
    • 0035816535 scopus 로고    scopus 로고
    • Drug delivery. Drugs on target
    • Langer R (2001) Drug delivery. Drugs on target. Science 293:58-59.
    • (2001) Science , vol.293 , pp. 58-59
    • Langer, R.1
  • 6
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • Duncan R (2003) The dawning era of polymer therapeutics. Nat Rev Drug Discov 2:347-360.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 347-360
    • Duncan, R.1
  • 7
    • 0029136052 scopus 로고
    • DNA complexes with polycations for the delivery of genetic material into cells
    • Kabanov AV and Kabanov VA (1995) DNA complexes with polycations for the delivery of genetic material into cells. Bioconjug Chem 6:7-20.
    • (1995) Bioconjug Chem , vol.6 , pp. 7-20
    • Kabanov, A.V.1    Kabanov, V.A.2
  • 8
    • 0037148675 scopus 로고    scopus 로고
    • Block copolymer micelles for delivery of gene and related compounds
    • Kakizawa Y and Kataoka K (2002) Block copolymer micelles for delivery of gene and related compounds. Adv Drug Del Rev 54:203-222.
    • (2002) Adv Drug Del Rev , vol.54 , pp. 203-222
    • Kakizawa, Y.1    Kataoka, K.2
  • 9
    • 0036000109 scopus 로고    scopus 로고
    • Pluronic block copolymers in drug delivery: From micellar nanocontainers to biological response modifiers
    • Kabanov AV and Alakhov VY (2002) Pluronic block copolymers in drug delivery: From micellar nanocontainers to biological response modifiers. Crit Rev Ther Drug Carr Syst 19:1-72.
    • (2002) Crit Rev Ther Drug Carr Syst , vol.19 , pp. 1-72
    • Kabanov, A.V.1    Alakhov, V.Y.2
  • 10
    • 0242584817 scopus 로고    scopus 로고
    • Micellar nanocontainers distribute to defined cytoplasmic organelles
    • Savic R, Luo L, Eisenberg A and Maysinger D (2003) Micellar nanocontainers distribute to defined cytoplasmic organelles. Science 300:615-618.
    • (2003) Science , vol.300 , pp. 615-618
    • Savic, R.1    Luo, L.2    Eisenberg, A.3    Maysinger, D.4
  • 11
    • 0037980258 scopus 로고    scopus 로고
    • Materials science. Enhancing drug function
    • Hubbell JA (2003) Materials science. Enhancing drug function. Science 300:595-596.
    • (2003) Science , vol.300 , pp. 595-596
    • Hubbell, J.A.1
  • 12
    • 0142090839 scopus 로고    scopus 로고
    • Multifunctional nanorods for gene delivery
    • Salem AK, Searson PC and Leong KW (2003) Multifunctional nanorods for gene delivery. Nat Mater 2:668-671.
    • (2003) Nat Mater , vol.2 , pp. 668-671
    • Salem, A.K.1    Searson, P.C.2    Leong, K.W.3
  • 14
    • 0033221068 scopus 로고    scopus 로고
    • Nano-engineering block copolymer aggregates for drug delivery
    • Allen C, Maysinger D and Eisenberg A (1999) Nano-engineering block copolymer aggregates for drug delivery. Coll Surf B: Biointerf 16:3-27.
    • (1999) Coll Surf B: Biointerf , vol.16 , pp. 3-27
    • Allen, C.1    Maysinger, D.2    Eisenberg, A.3
  • 15
    • 0035937592 scopus 로고    scopus 로고
    • Block copolymer micelles for drug delivery: Design, characterization and biological significance
    • Kataoka K, Harada A and Nagasaki Y (2001) Block copolymer micelles for drug delivery: Design, characterization and biological significance. Adv Drug Del Rev 47:113-131.
    • (2001) Adv Drug Del Rev , vol.47 , pp. 113-131
    • Kataoka, K.1    Harada, A.2    Nagasaki, Y.3
  • 16
    • 0038759662 scopus 로고    scopus 로고
    • Amphiphilic block copolymers for drug delivery
    • Adams ML, Lavasanifar A and Kwon GS (2003) Amphiphilic block copolymers for drug delivery. J Pharm Sci 92:1343-1355.
    • (2003) J Pharm Sci , vol.92 , pp. 1343-1355
    • Adams, M.L.1    Lavasanifar, A.2    Kwon, G.S.3
  • 17
    • 0035937591 scopus 로고    scopus 로고
    • Design of nanoparticles composed of graft copolymers for oral peptide delivery
    • Sakuma S, Hayashi M and Akashi M (2001) Design of nanoparticles composed of graft copolymers for oral peptide delivery. Adv Drug Del Rev 47:21-37.
    • (2001) Adv Drug Del Rev , vol.47 , pp. 21-37
    • Sakuma, S.1    Hayashi, M.2    Akashi, M.3
  • 18
    • 0242383500 scopus 로고    scopus 로고
    • Solubilization of cyclosporin A in dextran-g-polyethyleneglycolalkyl ether polymeric micelles
    • Francis MF, Lavoie L, Winnik FM and Leroux JC (2003) Solubilization of cyclosporin A in dextran-g-polyethyleneglycolalkyl ether polymeric micelles. Eur J Pharm Biopharm 56:337-346.
    • (2003) Eur J Pharm Biopharm , vol.56 , pp. 337-346
    • Francis, M.F.1    Lavoie, L.2    Winnik, F.M.3    Leroux, J.C.4
  • 19
    • 0242352524 scopus 로고    scopus 로고
    • Solubilization of poorly water soluble drugs in micelles of hydrophobically modified hydroxypropylcellulose copolymers
    • Francis MF, Piredda M and Winnik FM (2003) Solubilization of poorly water soluble drugs in micelles of hydrophobically modified hydroxypropylcellulose copolymers. J Control Rel 93:59-68.
    • (2003) J Control Rel , vol.93 , pp. 59-68
    • Francis, M.F.1    Piredda, M.2    Winnik, F.M.3
  • 20
    • 0142210489 scopus 로고    scopus 로고
    • Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers
    • Jeong B, Bae YH and Kim SW (2000) Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers. J Control Rel 63:155-163.
    • (2000) J Control Rel , vol.63 , pp. 155-163
    • Jeong, B.1    Bae, Y.H.2    Kim, S.W.3
  • 21
    • 0035966546 scopus 로고    scopus 로고
    • Biodegradable polymeric micelles composed of doxorubicin conjugated PLGA-PEG block copolymer
    • Yoo HS and Park TG (2001) Biodegradable polymeric micelles composed of doxorubicin conjugated PLGA-PEG block copolymer. J Control Rel 70:63-70.
    • (2001) J Control Rel , vol.70 , pp. 63-70
    • Yoo, H.S.1    Park, T.G.2
  • 22
    • 0002405110 scopus 로고
    • Soluble synthetic polymers as potential drug carriers
    • Duncan R and Kopecek J (1984) Soluble synthetic polymers as potential drug carriers. Adv Polym Sci 57:51-101.
    • (1984) Adv Polym Sci , vol.57 , pp. 51-101
    • Duncan, R.1    Kopecek, J.2
  • 23
    • 9944229543 scopus 로고    scopus 로고
    • Targeted polymeric micelles for delivery of poorly soluble drugs
    • Torchilin VP (2004) Targeted polymeric micelles for delivery of poorly soluble drugs. Cell Mol Life Sci 61:2549-2559.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2549-2559
    • Torchilin, V.P.1
  • 24
    • 0035850224 scopus 로고    scopus 로고
    • Structure and design of polymeric surfactant-based drug delivery systems
    • Torchilin VP (2001) Structure and design of polymeric surfactant-based drug delivery systems. J Control Rel 73:137-172.
    • (2001) J Control Rel , vol.73 , pp. 137-172
    • Torchilin, V.P.1
  • 25
    • 0034996764 scopus 로고    scopus 로고
    • Long-circulating and target-specific nanoparticles: Theory to practice
    • Moghimi SM, Hunter AC and Murray JC (2001) Long-circulating and target-specific nanoparticles: Theory to practice. Pharmacol Rev 53:283-318.
    • (2001) Pharmacol Rev , vol.53 , pp. 283-318
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 26
    • 0141921484 scopus 로고    scopus 로고
    • Micelles from polyethylene gly-col/phosphatidylethanolamine conjugates for tumor drug delivery
    • Lukyanov AN, Gao Z and Torchilin VP (2003) Micelles from polyethylene gly-col/phosphatidylethanolamine conjugates for tumor drug delivery. J Control Rel 91:97-102.
    • (2003) J Control Rel , vol.91 , pp. 97-102
    • Lukyanov, A.N.1    Gao, Z.2    Torchilin, V.P.3
  • 27
    • 15844399879 scopus 로고    scopus 로고
    • Ion-Induced morphological changes in “crew-cut” aggregates of amphiphilic block copolymers
    • Zhang L, Yu K and Eisenberg A (1996) Ion-Induced morphological changes in “crew-cut” aggregates of amphiphilic block copolymers. Science 272:1777-1779.
    • (1996) Science , vol.272 , pp. 1777-1779
    • Zhang, L.1    Yu, K.2    Eisenberg, A.3
  • 28
    • 0003902915 scopus 로고    scopus 로고
    • Micelles of amphilphilic block copolymers as vehicles for drug delivery
    • in, Alexandridis P and Lindman B (eds.), Elsevier: Amsterdam, Lausanne, New York, Oxford, Shannon, Singapore, Tokyo
    • Kabanov AV and Alakhov VY (2000) Micelles of amphilphilic block copolymers as vehicles for drug delivery, in, Alexandridis P and Lindman B (eds.) Amphiphilic Block Copolymers: Self-Assembly and Applications: Elsevier: Amsterdam, Lausanne, New York, Oxford, Shannon, Singapore, Tokyo, pp. 347-376.
    • (2000) Amphiphilic Block Copolymers: Self-Assembly and Applications , pp. 347-376
    • Kabanov, A.V.1    Alakhov, V.Y.2
  • 29
    • 0032915634 scopus 로고    scopus 로고
    • Soluble self-assembled block copolymers for drug delivery
    • Kwon GS and Okano T (1999) Soluble self-assembled block copolymers for drug delivery. Pharm Res 16:597-600.
    • (1999) Pharm Res , vol.16 , pp. 597-600
    • Kwon, G.S.1    Okano, T.2
  • 30
    • 4544369742 scopus 로고    scopus 로고
    • Synthesis and micelliza-tion of star-shaped poly (ethylene glycol)-block-poly(e-caprolactone)
    • Kim KH, Guo HC, Lim HJ, Huh J, Ahn C-H and Jo WH (2004) Synthesis and micelliza-tion of star-shaped poly (ethylene glycol)-block-poly(e-caprolactone). Macromolec Chem Phys 205:1684-1692.
    • (2004) Macromolec Chem Phys , vol.205 , pp. 1684-1692
    • Kim, K.H.1    Guo, H.C.2    Lim, H.J.3    Huh, J.4    Ahn, C.-H.5    Jo, W.H.6
  • 31
    • 0027698880 scopus 로고
    • Solution and solid-state properties of hybrid linear-dendritic block copolymers
    • Gitsov I and Frechet JMJ (1993) Solution and solid-state properties of hybrid linear-dendritic block copolymers. Macromolecules 26:6536-6546.
    • (1993) Macromolecules , vol.26 , pp. 6536-6546
    • Gitsov, I.1    Frechet, J.M.J.2
  • 32
    • 0034247275 scopus 로고    scopus 로고
    • Micelles with highly branched nanoporous interior: Solution properties and binding capabilities of amphiphilic copolymers with linear dendritic architecture
    • Gitsov I, Lambrych KR, Remnant VA and Pracitto R (2000) Micelles with highly branched nanoporous interior: Solution properties and binding capabilities of amphiphilic copolymers with linear dendritic architecture. J Polym Sci Part A: Polym Chem 38:2711-2727.
    • (2000) J Polym Sci Part A: Polym Chem , vol.38 , pp. 2711-2727
    • Gitsov, I.1    Lambrych, K.R.2    Remnant, V.A.3    Pracitto, R.4
  • 33
    • 1542341274 scopus 로고
    • Unimolecular micelles and globular amphiphiles: Dendritic macromolecules as novel recyclable solubilization agents
    • Org Bio-Org Chem (1972-1999)
    • Hawker CJ, Wooley KL and Frechet JMJ (1993) Unimolecular micelles and globular amphiphiles: Dendritic macromolecules as novel recyclable solubilization agents. J Chem Soc Perkin Trans 1: Org Bio-Org Chem (1972-1999):1287-1297.
    • (1993) J Chem Soc Perkin Trans , vol.1 , pp. 1287-1297
    • Hawker, C.J.1    Wooley, K.L.2    Frechet, J.M.J.3
  • 34
    • 0000561895 scopus 로고
    • Starburst dendrimers. 4. Covalently fixed unimolecular assemblages reiminiscent of spheroidal micelles
    • Tomalia DA, Berry V, Hall M and Hedstrand DM (1987) Starburst dendrimers. 4. Covalently fixed unimolecular assemblages reiminiscent of spheroidal micelles. Macromolecules 20:1164-1167.
    • (1987) Macromolecules , vol.20 , pp. 1164-1167
    • Tomalia, D.A.1    Berry, V.2    Hall, M.3    Hedstrand, D.M.4
  • 39
    • 0029953311 scopus 로고    scopus 로고
    • Stimuli-responsive hybrid macromolecules: Novel amphiphilic star copolymers with dendritic groups at the periphery
    • Gitsov I and Frechet JMJ (1996) Stimuli-responsive hybrid macromolecules: novel amphiphilic star copolymers with dendritic groups at the periphery. J Am Chem Soc 118:3785-3786.
    • (1996) J Am Chem Soc , vol.118 , pp. 3785-3786
    • Gitsov, I.1    Frechet, J.M.J.2
  • 40
    • 0033997598 scopus 로고    scopus 로고
    • Water-soluble dendritic unimolecular micelles: Their potential as drug delivery agents
    • Liu M, Kono K and Frechet JM (2000) Water-soluble dendritic unimolecular micelles: Their potential as drug delivery agents. J Control Rel 65:121-131.
    • (2000) J Control Rel , vol.65 , pp. 121-131
    • Liu, M.1    Kono, K.2    Frechet, J.M.3
  • 41
    • 0033657796 scopus 로고    scopus 로고
    • Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs
    • Kojima C, Kono K, Maruyama K and Takagishi T (2000) Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs. Bioconjug Chem 11:910-917.
    • (2000) Bioconjug Chem , vol.11 , pp. 910-917
    • Kojima, C.1    Kono, K.2    Maruyama, K.3    Takagishi, T.4
  • 42
    • 15244357889 scopus 로고    scopus 로고
    • Synthesis and evaluation of a star amphiphilic block copolymer from poly(epsilon-caprolactone) and poly(ethylene glycol) as a potential drug delivery carrier
    • Wang F, Bronich TK, Kabanov AV, Rauh RD and Roovers J (2005) Synthesis and evaluation of a star amphiphilic block copolymer from poly(epsilon-caprolactone) and poly(ethylene glycol) as a potential drug delivery carrier. Bioconjug Chem 16:397-405.
    • (2005) Bioconjug Chem , vol.16 , pp. 397-405
    • Wang, F.1    Bronich, T.K.2    Kabanov, A.V.3    Rauh, R.D.4    Roovers, J.5
  • 43
    • 0033595532 scopus 로고    scopus 로고
    • Starlike block copolymers with amphiphilic arms as models for unimolecular micelles
    • Heise A, Hedrick JL, Frank CW and Miller RD (1999) Starlike block copolymers with amphiphilic arms as models for unimolecular micelles. J Am Chem Soc 121:8647-8648.
    • (1999) J Am Chem Soc , vol.121 , pp. 8647-8648
    • Heise, A.1    Hedrick, J.L.2    Frank, C.W.3    Miller, R.D.4
  • 44
    • 0033096891 scopus 로고    scopus 로고
    • Unimolecular micelles: Synthesis and characterization of amphiphilic polymer systems
    • Liu H, Jiang A, Guo J and Uhrich KE (1999) Unimolecular micelles: synthesis and characterization of amphiphilic polymer systems. J Polym Sci Part A: Polym Chem 37: 703-711.
    • (1999) J Polym Sci Part A: Polym Chem , vol.37 , pp. 703-711
    • Liu, H.1    Jiang, A.2    Guo, J.3    Uhrich, K.E.4
  • 45
    • 0034746462 scopus 로고    scopus 로고
    • Micellization of quaternized poly(2-(dimethylamino)ethyl methacrylate)-block-poly(methyl methacrylate) copolymers in water
    • Antoun S, Gohy JF and Jerome R (2001) Micellization of quaternized poly(2-(dimethylamino)ethyl methacrylate)-block-poly(methyl methacrylate) copolymers in water. Polym 42:3641-3648.
    • (2001) Polym , vol.42 , pp. 3641-3648
    • Antoun, S.1    Gohy, J.F.2    Jerome, R.3
  • 46
    • 0038793493 scopus 로고    scopus 로고
    • pH-sensitive unimolecular polymeric micelles: Synthesis a novel drug carrier
    • Jones M-C, Ranger M and Leroux J-C (2003) pH-sensitive unimolecular polymeric micelles: Synthesis a novel drug carrier. Bioconjug Chem 14:774-781.
    • (2003) Bioconjug Chem , vol.14 , pp. 774-781
    • Jones, M.-C.1    Ranger, M.2    Leroux, J.-C.3
  • 47
    • 0000228942 scopus 로고
    • Preparation and properties of monodisperse branched polystyrene
    • Morton M, Helminiak TE, Gadkary SD and Bueche J (1962) Preparation and properties of monodisperse branched polystyrene. J Polym Sci 57:471-482.
    • (1962) J Polym Sci , vol.57 , pp. 471-482
    • Morton, M.1    Helminiak, T.E.2    Gadkary, S.D.3    Bueche, J.4
  • 48
    • 0037461418 scopus 로고    scopus 로고
    • Arborescent polystyrene-graft-poly(2-vinylpyridine) copolymers as unimolecular micelles. Synthesis from acetylated substrates
    • Gauthier M, Li J and Dockendorff J (2003) Arborescent polystyrene-graft-poly(2-vinylpyridine) copolymers as unimolecular micelles. Synthesis from acetylated substrates. Macromolecules 36:2642-2648.
    • (2003) Macromolecules , vol.36 , pp. 2642-2648
    • Gauthier, M.1    Li, J.2    Dockendorff, J.3
  • 49
    • 0033076145 scopus 로고    scopus 로고
    • Core-polymerized reactive micelles from heterotelechelic amphiphilic block copolymers
    • Iijima M, Nagasaki Y, Okada T, Kato M and Kataoka K (1999) Core-polymerized reactive micelles from heterotelechelic amphiphilic block copolymers. Macromolecules 32:1140-1146.
    • (1999) Macromolecules , vol.32 , pp. 1140-1146
    • Iijima, M.1    Nagasaki, Y.2    Okada, T.3    Kato, M.4    Kataoka, K.5
  • 51
    • 0030107509 scopus 로고    scopus 로고
    • Star polymers and nanospheres from cross-linkable diblock copolymers
    • Guo A, Liu G and Tao J (1996) Star polymers and nanospheres from cross-linkable diblock copolymers. Macromolecules 29:2487-2493.
    • (1996) Macromolecules , vol.29 , pp. 2487-2493
    • Guo, A.1    Liu, G.2    Tao, J.3
  • 52
    • 0033548243 scopus 로고    scopus 로고
    • Giant wormlike rubber micelles
    • Won Y-Y, Davis HT and Bates FS (1999) Giant wormlike rubber micelles. Science 283:960-963.
    • (1999) Science , vol.283 , pp. 960-963
    • Won, Y.-Y.1    Davis, H.T.2    Bates, F.S.3
  • 53
    • 0032828457 scopus 로고    scopus 로고
    • Stabilization and activation of Pluronic micelles for tumor-targeted drug delivery
    • Rapoport N (1999) Stabilization and activation of Pluronic micelles for tumor-targeted drug delivery. Coll Surf B: Biointerf 16:93-111.
    • (1999) Coll Surf B: Biointerf , vol.16 , pp. 93-111
    • Rapoport, N.1
  • 54
    • 0032876507 scopus 로고    scopus 로고
    • Shell crosslinked polymer micelles: Stabilized assemblies with great versatility and potential
    • Thurmond KB, II, Huang H, Clark CG, Jr., Kowalewski T and Wooley KL (1999) Shell crosslinked polymer micelles: Stabilized assemblies with great versatility and potential. Coll Surf B: Biointerf 16:45-54.
    • (1999) Coll Surf B: Biointerf , vol.16 , pp. 45-54
    • Thurmond, K.B.1    Huang, H.2    Clark, C.G.3    Kowalewski, T.4    Wooley, K.L.5
  • 55
    • 0034685469 scopus 로고    scopus 로고
    • Shell cross-linked nanoparticles containing hydrolytically degradable, crystalline core domains
    • Zhang Q, Remsen EE and Wooley KL (2000) Shell cross-linked nanoparticles containing hydrolytically degradable, crystalline core domains. J Am Chem Soc 122: 3642-3651.
    • (2000) J Am Chem Soc , vol.122 , pp. 3642-3651
    • Zhang, Q.1    Remsen, E.E.2    Wooley, K.L.3
  • 57
    • 84967598624 scopus 로고    scopus 로고
    • Novel block ionomer micelles with cross-linked ionic cores
    • Bronich TK and Kabanov AV (2004) Novel block ionomer micelles with cross-linked ionic cores. Polym Prepr 45:384-385.
    • (2004) Polym Prepr , vol.45 , pp. 384-385
    • Bronich, T.K.1    Kabanov, A.V.2
  • 59
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • Duncan R (2003) The dawning era of polymer therapeutics. Nat Rev Drug Discov 2:347-360.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 347-360
    • Duncan, R.1
  • 60
    • 0242662545 scopus 로고    scopus 로고
    • A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs
    • Bulmus V, Woodward M, Lin L, Murthy N, Stayton P and Hoffman A (2003) A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs. J Control Rel 93: 105-120.
    • (2003) J Control Rel , vol.93 , pp. 105-120
    • Bulmus, V.1    Woodward, M.2    Lin, L.3    Murthy, N.4    Stayton, P.5    Hoffman, A.6
  • 61
    • 0032870935 scopus 로고    scopus 로고
    • Bioconjugation in pharmaceutical chemistry
    • Veronese FM and Morpurgo M (1999) Bioconjugation in pharmaceutical chemistry. Farmaco 54:497-516.
    • (1999) Farmaco , vol.54 , pp. 497-516
    • Veronese, F.M.1    Morpurgo, M.2
  • 62
    • 3843138529 scopus 로고    scopus 로고
    • Release from polymeric prodrugs: Linkages and their degradation
    • D’Souza AJ and Topp EM (2004) Release from polymeric prodrugs: Linkages and their degradation. J Pharm Sci 93:1962-1979.
    • (2004) J Pharm Sci , vol.93 , pp. 1962-1979
    • D’Souza, A.J.1    Topp, E.M.2
  • 63
    • 0142119372 scopus 로고    scopus 로고
    • Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: Polymeric micelles that are responsive to intracellular pH change
    • S4640/1-S4640/11
    • Bae Y, Fukushima S, Harada A and Kataoka K (2003) Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: Polymeric micelles that are responsive to intracellular pH change. Angewandte Chemie, Int Edn 42:4640-4643, S4640/1-S4640/11.
    • (2003) Angewandte Chemie, Int Edn , vol.42 , pp. 4640-4643
    • Bae, Y.1    Fukushima, S.2    Harada, A.3    Kataoka, K.4
  • 64
    • 12344269847 scopus 로고    scopus 로고
    • Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy
    • Bae Y, Nishiyama N, Fukushima S, Koyama H, Yasuhiro M and Kataoka K (2005) Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy. Bioconjug Chem 16:122-130.
    • (2005) Bioconjug Chem , vol.16 , pp. 122-130
    • Bae, Y.1    Nishiyama, N.2    Fukushima, S.3    Koyama, H.4    Yasuhiro, M.5    Kataoka, K.6
  • 65
    • 0026454169 scopus 로고
    • Block copolymers as drug carriers
    • Yokoyama M (1992) Block copolymers as drug carriers. Crit Rev Ther Drug Carr Syst 9:213-248.
    • (1992) Crit Rev Ther Drug Carr Syst , vol.9 , pp. 213-248
    • Yokoyama, M.1
  • 66
    • 0027263356 scopus 로고
    • Analysis of micelle formation of an adriamycin-conjugated polyethylene glycol-poly(aspartic acid) block copolymer by gel permeation chromatography
    • Yokoyama M, Sugiyama T, Okano T, Sakurai Y, Naito M and Kataoka K (1993) Analysis of micelle formation of an adriamycin-conjugated polyethylene glycol-poly(aspartic acid) block copolymer by gel permeation chromatography. Pharm Res 10:895-899.
    • (1993) Pharm Res , vol.10 , pp. 895-899
    • Yokoyama, M.1    Sugiyama, T.2    Okano, T.3    Sakurai, Y.4    Naito, M.5    Kataoka, K.6
  • 67
    • 0032472352 scopus 로고    scopus 로고
    • Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor
    • Yokoyama M, Fukushima S, Uehara R, Okamoto K, Kataoka K, Sakurai Y and Okano T (1998) Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor. J Control Rel 50:79-92.
    • (1998) J Control Rel , vol.50 , pp. 79-92
    • Yokoyama, M.1    Fukushima, S.2    Uehara, R.3    Okamoto, K.4    Kataoka, K.5    Sakurai, Y.6    Okano, T.7
  • 69
    • 0002960925 scopus 로고    scopus 로고
    • Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(beta-benzyl L-aspartate) block copolymer micelles
    • La SB, Okano T and Kataoka K (1996) Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(beta-benzyl L-aspartate) block copolymer micelles. J Pharm Sci 85:85-90.
    • (1996) J Pharm Sci , vol.85 , pp. 85-90
    • La, S.B.1    Okano, T.2    Kataoka, K.3
  • 70
    • 0031722638 scopus 로고    scopus 로고
    • Incorporation of water-insoluble anticancer drug into polymeric micelles and control of their particle size
    • Yokoyama M, Satoh A, Sakurai Y, Okano T, Matsumura Y, Kakizoe T and Kataoka K (1998) Incorporation of water-insoluble anticancer drug into polymeric micelles and control of their particle size. J Control Rel 55:219-229.
    • (1998) J Control Rel , vol.55 , pp. 219-229
    • Yokoyama, M.1    Satoh, A.2    Sakurai, Y.3    Okano, T.4    Matsumura, Y.5    Kakizoe, T.6    Kataoka, K.7
  • 71
    • 0032509929 scopus 로고    scopus 로고
    • An AB block copolymer of oligo(methyl methacrylate) and poly(acrylic acid) for micellar delivery of hydrophobic drugs
    • Inoue T, Chen G, Nakamae K and Hoffman AS (1998) An AB block copolymer of oligo(methyl methacrylate) and poly(acrylic acid) for micellar delivery of hydrophobic drugs. J Control Rel 51:221-229.
    • (1998) J Control Rel , vol.51 , pp. 221-229
    • Inoue, T.1    Chen, G.2    Nakamae, K.3    Hoffman, A.S.4
  • 72
    • 0033991545 scopus 로고    scopus 로고
    • Polycaprolactone-b-poly(ethylene oxide) copolymer micelles as a delivery vehicle for dihydrotestosterone
    • Allen C, Han J, Yu Y, Maysinger D and Eisenberg A (2000) Polycaprolactone-b-poly(ethylene oxide) copolymer micelles as a delivery vehicle for dihydrotestosterone. J Control Rel 63:275-286.
    • (2000) J Control Rel , vol.63 , pp. 275-286
    • Allen, C.1    Han, J.2    Yu, Y.3    Maysinger, D.4    Eisenberg, A.5
  • 74
    • 0032828963 scopus 로고    scopus 로고
    • Development of copolymers of poly(DL-lactide) and methoxypolyethylene glycol as micellar carriers of paclitaxel
    • Burt HM, Zhang X, Toleikis P, Embree L and Hunter WL (1999) Development of copolymers of poly(DL-lactide) and methoxypolyethylene glycol as micellar carriers of paclitaxel. Coll Surf, B: Biointerf 16:161-171.
    • (1999) Coll Surf, B: Biointerf , vol.16 , pp. 161-171
    • Burt, H.M.1    Zhang, X.2    Toleikis, P.3    Embree, L.4    Hunter, W.L.5
  • 75
    • 0035834246 scopus 로고    scopus 로고
    • Micelles self-assembled from poly(ethylene oxide)-block-poly(N-hexyl stearate L-aspartamide) by a solvent evaporation method: Effect on the solubilization and haemolytic activity of amphotericin B
    • Lavasanifar A, Samuel J and Kwon GS (2001) Micelles self-assembled from poly(ethylene oxide)-block-poly(N-hexyl stearate L-aspartamide) by a solvent evaporation method: Effect on the solubilization and haemolytic activity of amphotericin B. J Control Rel 77:155-160.
    • (2001) J Control Rel , vol.77 , pp. 155-160
    • Lavasanifar, A.1    Samuel, J.2    Kwon, G.S.3
  • 76
    • 0036114580 scopus 로고    scopus 로고
    • Block copolymer micelles for the encapsulation and delivery of amphotericin B
    • Lavasanifar A, Samuel J, Sattari S and Kwon GS (2002) Block copolymer micelles for the encapsulation and delivery of amphotericin B. Pharm Res 19:418-422.
    • (2002) Pharm Res , vol.19 , pp. 418-422
    • Lavasanifar, A.1    Samuel, J.2    Sattari, S.3    Kwon, G.S.4
  • 77
    • 0027683882 scopus 로고
    • Molecular modeling of micelle formation and solubilization in block copolymer micelles. 1. A self-consistent meanfield lattice theory
    • Hurter PN, Scheutjens JMHM and Hatton TA (1993) Molecular modeling of micelle formation and solubilization in block copolymer micelles. 1. A self-consistent meanfield lattice theory. Macromolecules 26:5592-5601.
    • (1993) Macromolecules , vol.26 , pp. 5592-5601
    • Hurter, P.N.1    Scheutjens, J.M.H.M.2    Hatton, T.A.3
  • 78
    • 0030602289 scopus 로고    scopus 로고
    • Comparison of solubilization of hydrocarbons in (PEO-PPO) diblock versus (PEO-PPO-PEO) triblock copolymer micelles
    • Nagarajan R and Ganesh K (1996) Comparison of solubilization of hydrocarbons in (PEO-PPO) diblock versus (PEO-PPO-PEO) triblock copolymer micelles. J Coll Interf Sci 184:489-499.
    • (1996) J Coll Interf Sci , vol.184 , pp. 489-499
    • Nagarajan, R.1    Ganesh, K.2
  • 79
    • 0031097303 scopus 로고    scopus 로고
    • Strong solubilization of small molecules by triblockcopolymer micelles in selective solvents
    • Xing L and Mattice WL (1997) Strong solubilization of small molecules by triblockcopolymer micelles in selective solvents. Macromolecules 30:1711-1717.
    • (1997) Macromolecules , vol.30 , pp. 1711-1717
    • Xing, L.1    Mattice, W.L.2
  • 80
    • 0029634549 scopus 로고
    • Solubilization of aromatic solutes in block copolymers
    • Gadelle F, Koros WJ and Schechter RS (1995) Solubilization of aromatic solutes in block copolymers. Macromolecules 28:4883-4892.
    • (1995) Macromolecules , vol.28 , pp. 4883-4892
    • Gadelle, F.1    Koros, W.J.2    Schechter, R.S.3
  • 81
    • 0022675348 scopus 로고
    • Unusual selectivity in solubilization by block copolymer micelles
    • Nagarajan R, Barry M and Ruckenstein E (1986) Unusual selectivity in solubilization by block copolymer micelles. Langmuir 2:210-215.
    • (1986) Langmuir , vol.2 , pp. 210-215
    • Nagarajan, R.1    Barry, M.2    Ruckenstein, E.3
  • 82
    • 0346494420 scopus 로고    scopus 로고
    • Polymer-drug compatibility: A guide to the development of delivery systems for the anticancer agent, ellipticine
    • Liu J, Xiao Y and Allen C (2004) Polymer-drug compatibility: A guide to the development of delivery systems for the anticancer agent, ellipticine. J Pharm Sci 93:132-143.
    • (2004) J Pharm Sci , vol.93 , pp. 132-143
    • Liu, J.1    Xiao, Y.2    Allen, C.3
  • 83
    • 0024768776 scopus 로고
    • Block copolymer self-assembly in selective solvents: Theory of solubilization in spherical micelles
    • Nagarajan R and Ganesh K (1989) Block copolymer self-assembly in selective solvents: Theory of solubilization in spherical micelles. Macromolecules 22:4312-4325.
    • (1989) Macromolecules , vol.22 , pp. 4312-4325
    • Nagarajan, R.1    Ganesh, K.2
  • 84
    • 0026865920 scopus 로고
    • Solubilization of polycyclic aromatic hydrocarbons by poly(ethylene oxide-propylene oxide) block copolymer micelles: Effects of polymer structure
    • Hurter PN and Hatton TA (1992) Solubilization of polycyclic aromatic hydrocarbons by poly(ethylene oxide-propylene oxide) block copolymer micelles: Effects of polymer structure. Langmuir 8:1291-1299.
    • (1992) Langmuir , vol.8 , pp. 1291-1299
    • Hurter, P.N.1    Hatton, T.A.2
  • 85
    • 0033743807 scopus 로고    scopus 로고
    • Relationship between pluronic block copolymer structure, critical micellization concentration and partitioning coefficients of low molecular mass solutes
    • Kozlov MY, Melik-Nubarov NS, Batrakova EV and Kabanov AV (2000) Relationship between pluronic block copolymer structure, critical micellization concentration and partitioning coefficients of low molecular mass solutes. Macromolecules 33: 3305-3313.
    • (2000) Macromolecules , vol.33 , pp. 3305-3313
    • Kozlov, M.Y.1    Melik-Nubarov, N.S.2    Batrakova, E.V.3    Kabanov, A.V.4
  • 86
    • 0027663118 scopus 로고
    • Molecular modeling of micelle formation and solubilization in block copolymer micelles. 2. Lattice theory for monomers with internal degrees of freedom
    • Hurter PN, Scheutjens JMHM and Hatton TA (1993) Molecular modeling of micelle formation and solubilization in block copolymer micelles. 2. Lattice theory for monomers with internal degrees of freedom. Macromolecules 26:5030-5040.
    • (1993) Macromolecules , vol.26 , pp. 5030-5040
    • Hurter, P.N.1    Scheutjens, J.M.H.M.2    Hatton, T.A.3
  • 87
    • 0032474323 scopus 로고    scopus 로고
    • Release kinetics studies of aromatic molecules into water from block polymer micelles
    • Teng Y, Morrison ME, Munk P, Webber SE and Prochazka K (1998) Release kinetics studies of aromatic molecules into water from block polymer micelles. Macromolecules 31:3578-3587.
    • (1998) Macromolecules , vol.31 , pp. 3578-3587
    • Teng, Y.1    Morrison, M.E.2    Munk, P.3    Webber, S.E.4    Prochazka, K.5
  • 88
    • 0141732214 scopus 로고    scopus 로고
    • Interfacial solubilization of model amphiphilic molecules in block copolymer micelles
    • Choucair A and Eisenberg A (2003) Interfacial solubilization of model amphiphilic molecules in block copolymer micelles. J Am Chem Soc 125:11993-12000.
    • (2003) J Am Chem Soc , vol.125 , pp. 11993-12000
    • Choucair, A.1    Eisenberg, A.2
  • 89
    • 0032559233 scopus 로고    scopus 로고
    • Methoxy poly(ethylene glycol) and epsilon-caprolactone amphiphilic block copolymeric micelle containing indomethacin. II. Micelle formation and drug release behaviours
    • Kim SY, Shin IG, Lee YM, Cho CS and Sung YK (1998) Methoxy poly(ethylene glycol) and epsilon-caprolactone amphiphilic block copolymeric micelle containing indomethacin. II. Micelle formation and drug release behaviours. J Control Rel 51:13-22.
    • (1998) J Control Rel , vol.51 , pp. 13-22
    • Kim, S.Y.1    Shin, I.G.2    Lee, Y.M.3    Cho, C.S.4    Sung, Y.K.5
  • 91
    • 0029344655 scopus 로고
    • Formation of polyion complex micelles in an aqueous milieu from a pair of oppositely-charged block copolymers with poly(ethylene glycol) segments
    • Harada A and Kataoka K (1995) Formation of polyion complex micelles in an aqueous milieu from a pair of oppositely-charged block copolymers with poly(ethylene glycol) segments. Macromolecules 28:5294-5299.
    • (1995) Macromolecules , vol.28 , pp. 5294-5299
    • Harada, A.1    Kataoka, K.2
  • 92
    • 0032473546 scopus 로고    scopus 로고
    • Interpolyelectrolyte and block ionomer complexes for gene delivery: Physico-chemical aspects
    • Kabanov VA and Kabanov AV (1998) Interpolyelectrolyte and block ionomer complexes for gene delivery: Physico-chemical aspects. Adv Drug Del Rev 30:49-60.
    • (1998) Adv Drug Del Rev , vol.30 , pp. 49-60
    • Kabanov, V.A.1    Kabanov, A.V.2
  • 94
    • 0141620174 scopus 로고    scopus 로고
    • Environmentally responsive nanoparticles from block ionomer complexes: Effects of pH and ionic strength
    • Solomatin SV, Bronich TK, Eisenberg A, Kabanov VA and Kabanov AV (2003) Environmentally responsive nanoparticles from block ionomer complexes: Effects of pH and ionic strength. Langmuir 19:8069-8076.
    • (2003) Langmuir , vol.19 , pp. 8069-8076
    • Solomatin, S.V.1    Bronich, T.K.2    Eisenberg, A.3    Kabanov, V.A.4    Kabanov, A.V.5
  • 95
    • 0242494163 scopus 로고    scopus 로고
    • Polyion complex micelles entrapping cationic dendrimer porphyrin: Effective photosensitizer for photodynamic therapy of cancer
    • Zhang G-D, Harada A, Nishiyama N, Jiang D-L, Koyama H, Aida T and Kataoka K (2003) Polyion complex micelles entrapping cationic dendrimer porphyrin: Effective photosensitizer for photodynamic therapy of cancer. J Control Rel 93:141-150.
    • (2003) J Control Rel , vol.93 , pp. 141-150
    • Zhang, G.-D.1    Harada, A.2    Nishiyama, N.3    Jiang, D.-L.4    Koyama, H.5    Aida, T.6    Kataoka, K.7
  • 96
    • 6444243630 scopus 로고    scopus 로고
    • Supramolecular Nanocarrier of siRNA from PEG-Based Block Catiomer Carrying Diamine Side Chain with Distinctive pKa Directed To Enhance Intracellular Gene Silencing
    • Itaka K, Kanayama N, Nishiyama N, Jang W-D, Yamasaki Y, Nakamura K, Kawaguchi H and Kataoka K (2004) Supramolecular Nanocarrier of siRNA from PEG-Based Block Catiomer Carrying Diamine Side Chain with Distinctive pKa Directed To Enhance Intracellular Gene Silencing. J Am Chem Soc 126:13612-13613.
    • (2004) J Am Chem Soc , vol.126 , pp. 13612-13613
    • Itaka, K.1    Kanayama, N.2    Nishiyama, N.3    Jang, W.-D.4    Yamasaki, Y.5    Nakamura, K.6    Kawaguchi, H.7    Kataoka, K.8
  • 97
    • 0037548005 scopus 로고    scopus 로고
    • Structure, dispersion stability and dynamics of DNA and polycation complexes
    • Kim SW and Mahato R (eds.). Taylor & Francis; London, New York
    • Kabanov AV and Bronich TK (2002) Structure, dispersion stability and dynamics of DNA and polycation complexes, in Kim SW and Mahato R (eds.) Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics. Taylor & Francis; London, New York, pp. 164-189.
    • (2002) Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics , pp. 164-189
    • Kabanov, A.V.1    Bronich, T.K.2
  • 99
    • 0032803387 scopus 로고    scopus 로고
    • Preparation and characterization of self-assembled polymer-metal complex micelle from cis-dichlorodiammineplatinum(II) and poly(ethylene glycol)-poly(alpha.,.beta.-aspartic acid) block copolymer in an aqueous medium
    • Nishiyama N, Yokoyama M, Aoyagi T, Okano T, Sakurai Y and Kataoka K (1999) Preparation and characterization of self-assembled polymer-metal complex micelle from cis-dichlorodiammineplatinum(II) and poly(ethylene glycol)-poly(alpha.,.beta.-aspartic acid) block copolymer in an aqueous medium. Langmuir 15:377-383.
    • (1999) Langmuir , vol.15 , pp. 377-383
    • Nishiyama, N.1    Yokoyama, M.2    Aoyagi, T.3    Okano, T.4    Sakurai, Y.5    Kataoka, K.6
  • 101
    • 33845282754 scopus 로고
    • Structural aspects of platinum anticancer drug interactions with DNA
    • Sherman SE and Lippard SJ (1987) Structural aspects of platinum anticancer drug interactions with DNA. Chem Rev 87:1153-1181.
    • (1987) Chem Rev , vol.87 , pp. 1153-1181
    • Sherman, S.E.1    Lippard, S.J.2
  • 102
    • 0035816193 scopus 로고    scopus 로고
    • Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiammineplatinum(II) in the core
    • Nishiyama N and Kataoka K (2001) Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiammineplatinum(II) in the core. J Control Rel 74:83-94.
    • (2001) J Control Rel , vol.74 , pp. 83-94
    • Nishiyama, N.1    Kataoka, K.2
  • 105
    • 0034300888 scopus 로고    scopus 로고
    • Polyion complex micelles encapsulating light-harvesting ionic dendrimer zinc porphyrins
    • Stapert HR, Nishiyama N, Jiang D-L, Aida T and Kataoka K (2000) Polyion complex micelles encapsulating light-harvesting ionic dendrimer zinc porphyrins. Langmuir 16:8182-8188.
    • (2000) Langmuir , vol.16 , pp. 8182-8188
    • Stapert, H.R.1    Nishiyama, N.2    Jiang, D.-L.3    Aida, T.4    Kataoka, K.5
  • 106
    • 0031646316 scopus 로고    scopus 로고
    • Novel polyion complex micelles entrapping enzyme molecules in the core: Preparation of narrowly-distributed micelles from lysozyme and poly(ethylene glycol)-poly(aspartic acid) block copolymer in aqueous medium
    • Harada A and Kataoka K (1998) Novel polyion complex micelles entrapping enzyme molecules in the core: Preparation of narrowly-distributed micelles from lysozyme and poly(ethylene glycol)-poly(aspartic acid) block copolymer in aqueous medium. Macromolecules 31:288-294.
    • (1998) Macromolecules , vol.31 , pp. 288-294
    • Harada, A.1    Kataoka, K.2
  • 107
    • 16344368266 scopus 로고    scopus 로고
    • Acceleration of enzymatic reaction of trypsin through the formation of water-soluble complexes with poly(ethylene glycol)-block-poly(a,b-aspartic acid)
    • Kawamura A, Yoshioka Y, Harada A and Kono K (2005) Acceleration of enzymatic reaction of trypsin through the formation of water-soluble complexes with poly(ethylene glycol)-block-poly(a,b-aspartic acid). Biomacromolecules 6:627-631.
    • (2005) Biomacromolecules , vol.6 , pp. 627-631
    • Kawamura, A.1    Yoshioka, Y.2    Harada, A.3    Kono, K.4
  • 108
    • 0348110661 scopus 로고    scopus 로고
    • Switching by pulse electric field of the elevated enzymatic reaction in the core of polyion complex micelles
    • Harada A and Kataoka K (2003) Switching by pulse electric field of the elevated enzymatic reaction in the core of polyion complex micelles. J Am Chem Soc 125:15306-15307.
    • (2003) J Am Chem Soc , vol.125 , pp. 15306-15307
    • Harada, A.1    Kataoka, K.2
  • 109
    • 0031164083 scopus 로고    scopus 로고
    • Soluble complexes from poly(ethylene oxide)-block-polymethacrylate anions and N-alkylpyridinium cations
    • Bronich TK, Kabanov AV, Kabanov VA, Yu K and Eisenberg A (1997) Soluble complexes from poly(ethylene oxide)-block-polymethacrylate anions and N-alkylpyridinium cations. Macromolecules 30:3519-3525.
    • (1997) Macromolecules , vol.30 , pp. 3519-3525
    • Bronich, T.K.1    Kabanov, A.V.2    Kabanov, V.A.3    Yu, K.4    Eisenberg, A.5
  • 110
  • 111
    • 0032581954 scopus 로고    scopus 로고
    • Spontaneous formation of vesicles from complexes of block ionomers and surfactants
    • Kabanov AV, Bronich TK, Kabanov VA, Yu K and Eisenberg A (1998) Spontaneous formation of vesicles from complexes of block ionomers and surfactants. J Am Chem Soc 120:9941-9942.
    • (1998) J Am Chem Soc , vol.120 , pp. 9941-9942
    • Kabanov, A.V.1    Bronich, T.K.2    Kabanov, V.A.3    Yu, K.4    Eisenberg, A.5
  • 112
    • 0033639541 scopus 로고    scopus 로고
    • Effects of block length and structure of surfactant on self-assembly and solution behavior of block ionomer complexes
    • Bronich TK, Popov AM, Eisenberg A, Kabanov VA and Kabanov AV (2000) Effects of block length and structure of surfactant on self-assembly and solution behavior of block ionomer complexes. Langmuir 16:481-489.
    • (2000) Langmuir , vol.16 , pp. 481-489
    • Bronich, T.K.1    Popov, A.M.2    Eisenberg, A.3    Kabanov, V.A.4    Kabanov, A.V.5
  • 114
    • 0032863454 scopus 로고    scopus 로고
    • Novel drug delivery systems based on the complexes of block ionomers and surfactants of opposite charge
    • Bronich TK, Nehls A, Eisenberg A, Kabanov VA and Kabanov AV (1999) Novel drug delivery systems based on the complexes of block ionomers and surfactants of opposite charge. Col Surf B 16:243-251.
    • (1999) Col Surf B , vol.16 , pp. 243-251
    • Bronich, T.K.1    Nehls, A.2    Eisenberg, A.3    Kabanov, V.A.4    Kabanov, A.V.5
  • 115
    • 1842478176 scopus 로고    scopus 로고
    • Colloidal stability of aqueous dispersions of block ionomer complexes: Effects of temperature and salt
    • Solomatin SV, Bronich TK, Eisenberg A, Kabanov VA and Kabanov AV (2004) Colloidal stability of aqueous dispersions of block ionomer complexes: Effects of temperature and salt. Langmuir 20: 2066-2068.
    • (2004) Langmuir , vol.20 , pp. 2066-2068
    • Solomatin, S.V.1    Bronich, T.K.2    Eisenberg, A.3    Kabanov, V.A.4    Kabanov, A.V.5
  • 117
    • 0033932346 scopus 로고    scopus 로고
    • Cardiac peroxynitrite formation and left ventricular dysfunction following doxorubicin treatment in mice
    • Weinstein DM, Mihm MJ and Bauer JA (2000) Cardiac peroxynitrite formation and left ventricular dysfunction following doxorubicin treatment in mice. J Pharmacol Exp Ther 294:396-401.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 396-401
    • Weinstein, D.M.1    Mihm, M.J.2    Bauer, J.A.3
  • 118
    • 0029360757 scopus 로고
    • Block copolymer micelles as long-circulating drug vehicles
    • Kwon GS and Kataoka K (1995) Block copolymer micelles as long-circulating drug vehicles. Adv Drug Del Rev 16:295-309.
    • (1995) Adv Drug Del Rev , vol.16 , pp. 295-309
    • Kwon, G.S.1    Kataoka, K.2
  • 120
    • 0019813898 scopus 로고
    • Plasma clearance, tissue distribution and metabolism of hyaluronic acid injected intravenously in the rabbit
    • Fraser JR, Laurent TC, Pertoft H and Baxter E (1981) Plasma clearance, tissue distribution and metabolism of hyaluronic acid injected intravenously in the rabbit. Biochem J 200:415-424.
    • (1981) Biochem J , vol.200 , pp. 415-424
    • Fraser, J.R.1    Laurent, T.C.2    Pertoft, H.3    Baxter, E.4
  • 121
    • 0034989921 scopus 로고    scopus 로고
    • Synthetic macromolecular drug carriers: Biodistribution of poly[(N-2-hydroxypropyl)methacrylamide] copolymers and their accumulation in solid rat tumors
    • Kissel M, Peschke P, Subr V, Ulbrich K, Schuhmacher J, Debus J and Friedrich E (2001) Synthetic macromolecular drug carriers: Biodistribution of poly[(N-2-hydroxypropyl)methacrylamide] copolymers and their accumulation in solid rat tumors. PDA J Pharm Sci Technol 55:191-201.
    • (2001) PDA J Pharm Sci Technol , vol.55 , pp. 191-201
    • Kissel, M.1    Peschke, P.2    Subr, V.3    Ulbrich, K.4    Schuhmacher, J.5    Debus, J.6    Friedrich, E.7
  • 122
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y and Maeda H (1986) A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 46:6387-6392.
    • (1986) Cancer Res , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 123
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
    • Maeda H (2001) The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting. Adv Enzyme Regul 41:189-207.
    • (2001) Adv Enzyme Regul , vol.41 , pp. 189-207
    • Maeda, H.1
  • 124
    • 16244378596 scopus 로고    scopus 로고
    • Radiometallation of receptor-specific peptides for diagnosis and treatment of human cancer
    • Giblin MF, Veerendra B and Smith CJ (2005) Radiometallation of receptor-specific peptides for diagnosis and treatment of human cancer. In Vivo 19:9-29.
    • (2005) In Vivo , vol.19 , pp. 9-29
    • Giblin, M.F.1    Veerendra, B.2    Smith, C.J.3
  • 125
    • 16244379522 scopus 로고    scopus 로고
    • VEGF-targeted therapy in metastatic renal cell carcinoma
    • Rini BI (2005) VEGF-targeted therapy in metastatic renal cell carcinoma. Oncologist 10:191-197.
    • (2005) Oncologist , vol.10 , pp. 191-197
    • Rini, B.I.1
  • 126
    • 11344291754 scopus 로고    scopus 로고
    • The evolution of antibodies into versatile tumor-targeting agents
    • Lin MZ, Teitell MA and Schiller GJ (2005) The evolution of antibodies into versatile tumor-targeting agents. Clin Cancer Res 11:129-138.
    • (2005) Clin Cancer Res , vol.11 , pp. 129-138
    • Lin, M.Z.1    Teitell, M.A.2    Schiller, G.J.3
  • 127
    • 0019951301 scopus 로고
    • Lethal nephrotoxicity and hematologic toxicity of cis-diamminedichloroplatinum ameliorated by optimal circadian timing and hydration
    • Levi FA, Hrashesky WJ, Halberg F, Langevin TR, Haus E and Kennedy BJ (1982) Lethal nephrotoxicity and hematologic toxicity of cis-diamminedichloroplatinum ameliorated by optimal circadian timing and hydration. Eur J Cancer Clin Oncol 18:471-477.
    • (1982) Eur J Cancer Clin Oncol , vol.18 , pp. 471-477
    • Levi, F.A.1    Hrashesky, W.J.2    Halberg, F.3    Langevin, T.R.4    Haus, E.5    Kennedy, B.J.6
  • 128
    • 2942583635 scopus 로고    scopus 로고
    • SMA-doxorubicin, a new polymeric micellar drug for effective targeting to solid tumours
    • Greish K, Sawa T, Fang J, Akaike T and Maeda H (2004) SMA-doxorubicin, a new polymeric micellar drug for effective targeting to solid tumours. J Control Rel 97: 219-230.
    • (2004) J Control Rel , vol.97 , pp. 219-230
    • Greish, K.1    Sawa, T.2    Fang, J.3    Akaike, T.4    Maeda, H.5
  • 129
    • 14844303778 scopus 로고    scopus 로고
    • Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor
    • Lee ES, Na K and Bae YH (2005) Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor. J Control Rel 103:405-418.
    • (2005) J Control Rel , vol.103 , pp. 405-418
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 131
    • 0035858296 scopus 로고    scopus 로고
    • In vivo evaluation of polymeric micellar paclitaxel formulation: Toxicity and efficacy
    • Kim SC, Kim DW, Shim YH, Bang JS, Oh HS, Wan Kim S and Seo MH (2001) In vivo evaluation of polymeric micellar paclitaxel formulation: Toxicity and efficacy. J Control Rel 72:191-202.
    • (2001) J Control Rel , vol.72 , pp. 191-202
    • Kim, S.C.1    Kim, D.W.2    Shim, Y.H.3    Bang, J.S.4    Oh, H.S.5    Wan Kim, S.6    Seo, M.H.7
  • 133
    • 0035134917 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of pH-responsive polymeric micelles in a photodynamic cancer therapy model
    • Taillefer J, Brasseur N, van Lier JE, Lenaerts V, Le Garrec D and Leroux JC (2001) In vitro and in vivo evaluation of pH-responsive polymeric micelles in a photodynamic cancer therapy model. J Pharm Pharmacol 53:155-166.
    • (2001) J Pharm Pharmacol , vol.53 , pp. 155-166
    • Taillefer, J.1    Brasseur, N.2    Van Lier, J.E.3    Lenaerts, V.4    Le Garrec, D.5    Leroux, J.C.6
  • 134
    • 0035994313 scopus 로고    scopus 로고
    • Optimizing pH-responsive polymeric micelles for drug delivery in a cancer photodynamic therapy model
    • Le Garrec D, Taillefer J, Van Lier JE, Lenaerts V and Leroux JC (2002) Optimizing pH-responsive polymeric micelles for drug delivery in a cancer photodynamic therapy model. J Drug Targ 10:429-437.
    • (2002) J Drug Targ , vol.10 , pp. 429-437
    • Le Garrec, D.1    Taillefer, J.2    Van Lier, J.E.3    Lenaerts, V.4    Leroux, J.C.5
  • 135
    • 0033233187 scopus 로고    scopus 로고
    • Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system
    • Yokoyama M, Okano T, Sakurai Y, Fukushima S, Okamoto K and Kataoka K (1999) Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system. J Drug Targ 7:171-186.
    • (1999) J Drug Targ , vol.7 , pp. 171-186
    • Yokoyama, M.1    Okano, T.2    Sakurai, Y.3    Fukushima, S.4    Okamoto, K.5    Kataoka, K.6
  • 136
    • 12344272662 scopus 로고    scopus 로고
    • Copoly(styrene-maleic acid)-pirarubicin micelles: High tumor-targeting efficiency with little toxicity
    • Greish K, Nagamitsu A, Fang J and Maeda H (2005) Copoly(styrene-maleic acid)-pirarubicin micelles: High tumor-targeting efficiency with little toxicity. Bioconjug Chem 16:230-236.
    • (2005) Bioconjug Chem , vol.16 , pp. 230-236
    • Greish, K.1    Nagamitsu, A.2    Fang, J.3    Maeda, H.4
  • 138
    • 1942503257 scopus 로고    scopus 로고
    • Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis
    • Paulos CM, Turk MJ, Breur GJ and Low PS (2004) Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis. Adv Drug Del Rev 56:1205-1217.
    • (2004) Adv Drug Del Rev , vol.56 , pp. 1205-1217
    • Paulos, C.M.1    Turk, M.J.2    Breur, G.J.3    Low, P.S.4
  • 139
    • 1842638560 scopus 로고    scopus 로고
    • Folate receptor targeted biodegradable polymeric doxorubicin micelles
    • Yoo HS and Park TG (2004) Folate receptor targeted biodegradable polymeric doxorubicin micelles. J Control Rel 96:273-283.
    • (2004) J Control Rel , vol.96 , pp. 273-283
    • Yoo, H.S.1    Park, T.G.2
  • 140
    • 0036781811 scopus 로고    scopus 로고
    • Ligand-targeted therapeutics in anticancer therapy
    • Allen TM (2002) Ligand-targeted therapeutics in anticancer therapy. Nat Rev Cancer 2:750-763.
    • (2002) Nat Rev Cancer , vol.2 , pp. 750-763
    • Allen, T.M.1
  • 141
    • 0038268753 scopus 로고    scopus 로고
    • PEG-PE/phosphatidylcholine mixed immunomicelles specifically deliver encapsulated taxol to tumor cells of different origin and promote their efficient killing
    • Gao Z, Lukyanov AN, Chakilam AR and Torchilin VP (2003) PEG-PE/phosphatidylcholine mixed immunomicelles specifically deliver encapsulated taxol to tumor cells of different origin and promote their efficient killing. J Drug Targ 11:87-92.
    • (2003) J Drug Targ , vol.11 , pp. 87-92
    • Gao, Z.1    Lukyanov, A.N.2    Chakilam, A.R.3    Torchilin, V.P.4
  • 142
    • 0024379967 scopus 로고
    • Acid pH in tumors and its potential for therapeutic exploitation
    • Tannock IF and Rotin D (1989) Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res 49:4373-4384.
    • (1989) Cancer Res , vol.49 , pp. 4373-4384
    • Tannock, I.F.1    Rotin, D.2
  • 143
    • 0033980297 scopus 로고    scopus 로고
    • Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-L-aspartate) copolymer micelles: Their pharmaceutical characteristics and biological significance
    • Kataoka K, Matsumoto T, Yokoyama M, Okano T, Sakurai Y, Fukushima S, Okamoto K and Kwon GS (2000) Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-L-aspartate) copolymer micelles: Their pharmaceutical characteristics and biological significance. J Control Rel 64:143-153.
    • (2000) J Control Rel , vol.64 , pp. 143-153
    • Kataoka, K.1    Matsumoto, T.2    Yokoyama, M.3    Okano, T.4    Sakurai, Y.5    Fukushima, S.6    Okamoto, K.7    Kwon, G.S.8
  • 144
    • 0037130252 scopus 로고    scopus 로고
    • Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages
    • Yoo HS, Lee EA and Park TG (2002) Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages. J Control Rel 82:17-27.
    • (2002) J Control Rel , vol.82 , pp. 17-27
    • Yoo, H.S.1    Lee, E.A.2    Park, T.G.3
  • 145
    • 13844269029 scopus 로고    scopus 로고
    • Polymeric micellar pH-sensitive drug delivery system for doxorubicin
    • Hruby M, Konak C and Ulbrich K (2005) Polymeric micellar pH-sensitive drug delivery system for doxorubicin. J Control Rel 103:137-148.
    • (2005) J Control Rel , vol.103 , pp. 137-148
    • Hruby, M.1    Konak, C.2    Ulbrich, K.3
  • 146
    • 0030573881 scopus 로고    scopus 로고
    • Soluble stoichiometric complexes from poly(N-ethyl-4-vinylpyridinium) cations and poly(ethylene oxide)-block-polymethacrylate anions
    • Kabanov AV, Bronich TK, Kabanov VA, Yu K and Eisenberg A (1996) Soluble stoichiometric complexes from poly(N-ethyl-4-vinylpyridinium) cations and poly(ethylene oxide)-block-polymethacrylate anions. Macromolecules 29:6797-6802.
    • (1996) Macromolecules , vol.29 , pp. 6797-6802
    • Kabanov, A.V.1    Bronich, T.K.2    Kabanov, V.A.3    Yu, K.4    Eisenberg, A.5
  • 147
    • 0038106270 scopus 로고    scopus 로고
    • Poly(L-histidine)-PEG block copolymer micelles and pH-induced destabilization
    • Lee ES, Shin HJ, Na K and Bae YH (2003) Poly(L-histidine)-PEG block copolymer micelles and pH-induced destabilization. J Control Rel 90:363-374.
    • (2003) J Control Rel , vol.90 , pp. 363-374
    • Lee, E.S.1    Shin, H.J.2    Na, K.3    Bae, Y.H.4
  • 148
    • 0030111359 scopus 로고    scopus 로고
    • Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer
    • Alakhov VY, Moskaleva EY, Batrakova EV and Kabanov AV (1996) Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer. Bioconjug Chem 7:209-216.
    • (1996) Bioconjug Chem , vol.7 , pp. 209-216
    • Alakhov, V.Y.1    Moskaleva, E.Y.2    Batrakova, E.V.3    Kabanov, A.V.4
  • 149
    • 0029765581 scopus 로고    scopus 로고
    • Hypersensitizing effect of pluronic L61 on cytotoxic activity, transport, and subcellular distribution of doxorubicin in multiple drug-resistant cells
    • Venne A, Li S, Mandeville R, Kabanov A and Alakhov V (1996) Hypersensitizing effect of pluronic L61 on cytotoxic activity, transport, and subcellular distribution of doxorubicin in multiple drug-resistant cells. Cancer Res 56:3626-3629.
    • (1996) Cancer Res , vol.56 , pp. 3626-3629
    • Venne, A.1    Li, S.2    Mandeville, R.3    Kabanov, A.4    Alakhov, V.5
  • 151
    • 0037072478 scopus 로고    scopus 로고
    • Pluronic block copolymers for overcoming drug resistance in cancer
    • Kabanov AV, Batrakova EV and Alakhov VY (2002) Pluronic block copolymers for overcoming drug resistance in cancer. Adv Drug Deliv Rev 54:759-779.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 759-779
    • Kabanov, A.V.1    Batrakova, E.V.2    Alakhov, V.Y.3
  • 152
    • 0032862767 scopus 로고    scopus 로고
    • Fundamental relationships between the composition of pluronic block copolymers and their hypersensitization effect in MDR cancer cells
    • Batrakova EV, Lee S, Li S, Venne A, Alakhov V and Kabanov A (1999) Fundamental relationships between the composition of pluronic block copolymers and their hypersensitization effect in MDR cancer cells. Pharm Res 16:1373-1379.
    • (1999) Pharm Res , vol.16 , pp. 1373-1379
    • Batrakova, E.V.1    Lee, S.2    Li, S.3    Venne, A.4    Alakhov, V.5    Kabanov, A.6
  • 153
    • 0032929216 scopus 로고    scopus 로고
    • Inhibition of multidrug resistance-associated protein (MRP) functional activity with pluronic block copolymers
    • Miller DW, Batrakova EV and Kabanov AV (1999) Inhibition of multidrug resistance-associated protein (MRP) functional activity with pluronic block copolymers. Pharm Res 16:396-401.
    • (1999) Pharm Res , vol.16 , pp. 396-401
    • Miller, D.W.1    Batrakova, E.V.2    Kabanov, A.V.3
  • 155
    • 21744444124 scopus 로고    scopus 로고
    • Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells
    • Minko T, Batrakova E, Li S, Li Y, Pakunlu R, Alakhov V and Kabanov A (2005) Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells. J Control Rel.
    • (2005) J Control Rel
    • Minko, T.1    Batrakova, E.2    Li, S.3    Li, Y.4    Pakunlu, R.5    Alakhov, V.6    Kabanov, A.7
  • 156
    • 0031665981 scopus 로고    scopus 로고
    • Effects of pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells
    • Batrakova EV, Han HY, Miller DW and Kabanov AV (1998) Effects of pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells. Pharm Res 15:1525-1532.
    • (1998) Pharm Res , vol.15 , pp. 1525-1532
    • Batrakova, E.V.1    Han, H.Y.2    Miller, D.W.3    Kabanov, A.V.4
  • 157
    • 0033922511 scopus 로고    scopus 로고
    • Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1-and MRP2-mediated transport
    • Evers R, Kool M, Smith AJ, van Deemter L, de Haas M and Borst P (2000) Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1-and MRP2-mediated transport. Br J Cancer 83:366-374.
    • (2000) Br J Cancer , vol.83 , pp. 366-374
    • Evers, R.1    Kool, M.2    Smith, A.J.3    Van Deemter, L.4    De Haas, M.5    Borst, P.6
  • 159
    • 0031239096 scopus 로고    scopus 로고
    • Interactions of pluronic block copolymers with brain microvessel endothelial cells: Evidence of two potential pathways for drug absorption
    • Miller DW, Batrakova EV, Waltner TO, Alakhov V and Kabanov AV (1997) Interactions of pluronic block copolymers with brain microvessel endothelial cells: Evidence of two potential pathways for drug absorption. Bioconjug Chem 8:649-657.
    • (1997) Bioconjug Chem , vol.8 , pp. 649-657
    • Miller, D.W.1    Batrakova, E.V.2    Waltner, T.O.3    Alakhov, V.4    Kabanov, A.V.5
  • 160
    • 0035556313 scopus 로고    scopus 로고
    • Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion
    • Batrakova EV, Li S, Elmquist WF, Miller DW, Alakhov VY and Kabanov AV (2001) Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion. Br J Cancer 85:1987-1997.
    • (2001) Br J Cancer , vol.85 , pp. 1987-1997
    • Batrakova, E.V.1    Li, S.2    Elmquist, W.F.3    Miller, D.W.4    Alakhov, V.Y.5    Kabanov, A.V.6
  • 161
    • 0034757615 scopus 로고    scopus 로고
    • Mechanism of pluronic effect on P-glycoprotein efflux system in blood-brain barrier: Contributions of energy depletion and membrane fluidization
    • Batrakova EV, Li S, Vinogradov SV, Alakhov VY, Miller DW and Kabanov AV (2001) Mechanism of pluronic effect on P-glycoprotein efflux system in blood-brain barrier: Contributions of energy depletion and membrane fluidization. J Pharmacol Exp Ther 299:483-493.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 483-493
    • Batrakova, E.V.1    Li, S.2    Vinogradov, S.V.3    Alakhov, V.Y.4    Miller, D.W.5    Kabanov, A.V.6
  • 162
    • 0037309349 scopus 로고    scopus 로고
    • Optimal structure requirements for Pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells
    • Batrakova EV, Li S, Alakhov VY, Miller DW and Kabanov AV (2003) Optimal structure requirements for Pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells. J Pharmacol Exp Ther 304:845-854.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 845-854
    • Batrakova, E.V.1    Li, S.2    Alakhov, V.Y.3    Miller, D.W.4    Kabanov, A.V.5
  • 163
    • 0034544430 scopus 로고    scopus 로고
    • Effect of a polymeric surfactant on electron transport in HL-60 cells
    • Rapoport N, Marin AP and Timoshin AA (2000) Effect of a polymeric surfactant on electron transport in HL-60 cells. Arch Biochem Biophys 384:100-108.
    • (2000) Arch Biochem Biophys , vol.384 , pp. 100-108
    • Rapoport, N.1    Marin, A.P.2    Timoshin, A.A.3
  • 164
    • 0141955916 scopus 로고    scopus 로고
    • An essential relationship between ATP depletion and chemosensitizing activity of Pluronic block copolymers
    • Kabanov AV, Batrakova EV and Alakhov VY (2003) An essential relationship between ATP depletion and chemosensitizing activity of Pluronic block copolymers. J Control Rel 91:75-83.
    • (2003) J Control Rel , vol.91 , pp. 75-83
    • Kabanov, A.V.1    Batrakova, E.V.2    Alakhov, V.Y.3
  • 165
    • 0032883658 scopus 로고    scopus 로고
    • Pluronic P85 increases permeability of a broad spectrum of drugs in polarized BBMEC and Caco-2 cell monolayers
    • Batrakova EV, Li S, Miller DW and Kabanov AV (1999) Pluronic P85 increases permeability of a broad spectrum of drugs in polarized BBMEC and Caco-2 cell monolayers. Pharm Res 16:1366-1372.
    • (1999) Pharm Res , vol.16 , pp. 1366-1372
    • Batrakova, E.V.1    Li, S.2    Miller, D.W.3    Kabanov, A.V.4
  • 167
    • 0037457792 scopus 로고    scopus 로고
    • Pluronic((R)) block copolymers as modulators of drug efflux transporter activity in the blood-brain barrier
    • Kabanov AV, Batrakova EV and Miller DW (2003) Pluronic((R)) block copolymers as modulators of drug efflux transporter activity in the blood-brain barrier. Adv Drug Del Rev 55:151-164.
    • (2003) Adv Drug Del Rev , vol.55 , pp. 151-164
    • Kabanov, A.V.1    Batrakova, E.V.2    Miller, D.W.3
  • 168
    • 2342424322 scopus 로고    scopus 로고
    • New technologies for drug delivery across the blood brain barrier
    • Kabanov AV and Batrakova EV (2004) New technologies for drug delivery across the blood brain barrier. Curr Pharm Des 10:1355-1363.
    • (2004) Curr Pharm Des , vol.10 , pp. 1355-1363
    • Kabanov, A.V.1    Batrakova, E.V.2
  • 169
    • 1642541103 scopus 로고    scopus 로고
    • Polymeric micelles for delivery of poorly water-soluble compounds
    • Kwon GS (2003) Polymeric micelles for delivery of poorly water-soluble compounds. Crit Rev Ther Drug Carr Syst 20:357-403.
    • (2003) Crit Rev Ther Drug Carr Syst , vol.20 , pp. 357-403
    • Kwon, G.S.1
  • 170
    • 0037458831 scopus 로고    scopus 로고
    • Relative aggregation state and hemolytic activity of amphotericin B encapsulated by poly(ethylene oxide)-block-poly(N-hexyl-L-aspartamide)-acyl conjugate micelles: Effects of acyl chain length
    • Adams ML and Kwon GS (2003) Relative aggregation state and hemolytic activity of amphotericin B encapsulated by poly(ethylene oxide)-block-poly(N-hexyl-L-aspartamide)-acyl conjugate micelles: Effects of acyl chain length. J Control Rel 87:23-32.
    • (2003) J Control Rel , vol.87 , pp. 23-32
    • Adams, M.L.1    Kwon, G.S.2
  • 171
    • 0037502795 scopus 로고    scopus 로고
    • Amphotericin B encapsulated in micelles based on poly(ethylene oxide)-block-poly(L-amino acid) derivatives exerts reduced in vitro hemolysis but maintains potent in vivo antifungal activity
    • Adams ML, Andes DR and Kwon GS (2003) Amphotericin B encapsulated in micelles based on poly(ethylene oxide)-block-poly(L-amino acid) derivatives exerts reduced in vitro hemolysis but maintains potent in vivo antifungal activity. Biomacromolecules 4:750-757.
    • (2003) Biomacromolecules , vol.4 , pp. 750-757
    • Adams, M.L.1    Andes, D.R.2    Kwon, G.S.3
  • 172
    • 1242271298 scopus 로고    scopus 로고
    • The effects of Pluronic block copolymers on the aggregation state of nystatin
    • Croy SR and Kwon GS (2004) The effects of Pluronic block copolymers on the aggregation state of nystatin. J Control Rel 95:161-171.
    • (2004) J Control Rel , vol.95 , pp. 161-171
    • Croy, S.R.1    Kwon, G.S.2
  • 173
    • 0034691583 scopus 로고    scopus 로고
    • Effect of poloxamer CRL-1072 on drug uptake and nitric-oxide-mediated killing of Mycobacterium avium by macrophages
    • Jagannath C, Sepulveda E, Actor JK, Luxem F, Emanuele MR and Hunter RL (2000) Effect of poloxamer CRL-1072 on drug uptake and nitric-oxide-mediated killing of Mycobacterium avium by macrophages. Immunopharmacology 48: 185-197.
    • (2000) Immunopharmacology , vol.48 , pp. 185-197
    • Jagannath, C.1    Sepulveda, E.2    Actor, J.K.3    Luxem, F.4    Emanuele, M.R.5    Hunter, R.L.6
  • 174
    • 0034091268 scopus 로고    scopus 로고
    • Activity of poloxamer CRL-1072 against drug-sensitive and resistant strains of Mycobacterium tuberculosis in macrophages and in mice
    • Jagannath C, Emanuele MR and Hunter RL (2000) Activity of poloxamer CRL-1072 against drug-sensitive and resistant strains of Mycobacterium tuberculosis in macrophages and in mice. Int J Antimicrob Agents 15:55-63.
    • (2000) Int J Antimicrob Agents , vol.15 , pp. 55-63
    • Jagannath, C.1    Emanuele, M.R.2    Hunter, R.L.3
  • 175
    • 0032795716 scopus 로고    scopus 로고
    • Activities of poloxamer CRL-1072 against Mycobacterium avium in macrophage culture and in mice
    • Jagannath C, Emanuele MR and Hunter RL (1999) Activities of poloxamer CRL-1072 against Mycobacterium avium in macrophage culture and in mice. Antimicrob Agents Chemother 43:2898-2903.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 2898-2903
    • Jagannath, C.1    Emanuele, M.R.2    Hunter, R.L.3
  • 177
    • 0037148667 scopus 로고    scopus 로고
    • PEG-based micelles as carriers of contrast agents for different imaging modalities
    • Torchilin VP (2002) PEG-based micelles as carriers of contrast agents for different imaging modalities. Adv Drug Del Rev 54:235-252.
    • (2002) Adv Drug Del Rev , vol.54 , pp. 235-252
    • Torchilin, V.P.1
  • 178
    • 0030095150 scopus 로고    scopus 로고
    • Stable polymeric micelles: Lymphangiographic contrast media for gamma scintigraphy and magnetic resonance imaging
    • Trubetskoy VS, Frank-Kamenetsky MD, Whiteman KR, Wolf GL and Torchilin VP (1996) Stable polymeric micelles: Lymphangiographic contrast media for gamma scintigraphy and magnetic resonance imaging. Acad Radiol 3:232-238.
    • (1996) Acad Radiol , vol.3 , pp. 232-238
    • Trubetskoy, V.S.1    Frank-Kamenetsky, M.D.2    Whiteman, K.R.3    Wolf, G.L.4    Torchilin, V.P.5
  • 179
    • 8544254690 scopus 로고    scopus 로고
    • Block-copolymer of polyethylene glycol and polylysine as a carrier of organic iodine: Design of long-circulating particulate contrast medium for X-ray computed tomography
    • Trubetskoy VS, Gazelle GS, Wolf GL and Torchilin VP (1997) Block-copolymer of polyethylene glycol and polylysine as a carrier of organic iodine: Design of long-circulating particulate contrast medium for X-ray computed tomography. J Drug Targ 4:381-388.
    • (1997) J Drug Targ , vol.4 , pp. 381-388
    • Trubetskoy, V.S.1    Gazelle, G.S.2    Wolf, G.L.3    Torchilin, V.P.4
  • 180
    • 0031665983 scopus 로고    scopus 로고
    • Accumulation of protein-loaded long-circulating micelles and liposomes in subcutaneous Lewis lung carcinoma in mice
    • Weissig V, Whiteman KR and Torchilin VP (1998) Accumulation of protein-loaded long-circulating micelles and liposomes in subcutaneous Lewis lung carcinoma in mice. Pharm Res 15:1552-1556.
    • (1998) Pharm Res , vol.15 , pp. 1552-1556
    • Weissig, V.1    Whiteman, K.R.2    Torchilin, V.P.3
  • 181
    • 0031239718 scopus 로고    scopus 로고
    • Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer
    • Katayose S and Kataoka K (1997) Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer. Bioconj Chem 8:702-707.
    • (1997) Bioconj Chem , vol.8 , pp. 702-707
    • Katayose, S.1    Kataoka, K.2
  • 182
    • 0029801424 scopus 로고    scopus 로고
    • Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers
    • Wolfert MA, Schacht EH, Toncheva V, Ulbrich K, Nazarova O and Seymour LW (1996) Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers. Hum Gene Ther 7:2123-2133.
    • (1996) Hum Gene Ther , vol.7 , pp. 2123-2133
    • Wolfert, M.A.1    Schacht, E.H.2    Toncheva, V.3    Ulbrich, K.4    Nazarova, O.5    Seymour, L.W.6
  • 183
    • 0032213191 scopus 로고    scopus 로고
    • Self-assembly of polyamine-poly(ethylene glycol) copolymers with phosphorothioate oligonucleotides
    • Vinogradov SV, Bronich TK and Kabanov AV (1998) Self-assembly of polyamine-poly(ethylene glycol) copolymers with phosphorothioate oligonucleotides. Bioconjug Chem 9:805-812.
    • (1998) Bioconjug Chem , vol.9 , pp. 805-812
    • Vinogradov, S.V.1    Bronich, T.K.2    Kabanov, A.V.3
  • 184
    • 0036057165 scopus 로고    scopus 로고
    • Evaluation by fluorescence resonance energy transfer of the stability of nonviral gene delivery vectors under physiological conditions
    • Itaka K, Harada A, Nakamura K, Kawaguchi H and Kataoka K (2002) Evaluation by fluorescence resonance energy transfer of the stability of nonviral gene delivery vectors under physiological conditions. Biomacromolecules 3:841-845.
    • (2002) Biomacromolecules , vol.3 , pp. 841-845
    • Itaka, K.1    Harada, A.2    Nakamura, K.3    Kawaguchi, H.4    Kataoka, K.5
  • 185
    • 0032937539 scopus 로고    scopus 로고
    • Reduction of fibronectin expression by intravitreal administration of antisense oligonucleotides
    • Roy S, Zhang K, Roth T, Vinogradov S, Kao RS and Kabanov A (1999) Reduction of fibronectin expression by intravitreal administration of antisense oligonucleotides. Nat Biotechnol 17:476-479.
    • (1999) Nat Biotechnol , vol.17 , pp. 476-479
    • Roy, S.1    Zhang, K.2    Roth, T.3    Vinogradov, S.4    Kao, R.S.5    Kabanov, A.6
  • 186
    • 0031788165 scopus 로고    scopus 로고
    • The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
    • Ogris M, Steinlein P, Kursa M, Mechtler K, Kircheis R and Wagner E (1998) The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther 5:1425-1433.
    • (1998) Gene Ther , vol.5 , pp. 1425-1433
    • Ogris, M.1    Steinlein, P.2    Kursa, M.3    Mechtler, K.4    Kircheis, R.5    Wagner, E.6
  • 187
    • 0036225362 scopus 로고    scopus 로고
    • Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation
    • Oupicky D, Ogris M, Howard KA, Dash PR, Ulbrich K and Seymour LW (2002) Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation. Mol Ther 5:463-472.
    • (2002) Mol Ther , vol.5 , pp. 463-472
    • Oupicky, D.1    Ogris, M.2    Howard, K.A.3    Dash, P.R.4    Ulbrich, K.5    Seymour, L.W.6
  • 188
    • 85047695467 scopus 로고    scopus 로고
    • Polyion complex micelles as vectors in gene therapy-pharmacokinetics and in vivo gene transfer
    • Harada-Shiba M, Yamauchi K, Harada A, Takamisawa I, Shimokado K and Kataoka K (2002) Polyion complex micelles as vectors in gene therapy-pharmacokinetics and in vivo gene transfer. Gene Ther 9:407-414.
    • (2002) Gene Ther , vol.9 , pp. 407-414
    • Harada-Shiba, M.1    Yamauchi, K.2    Harada, A.3    Takamisawa, I.4    Shimokado, K.5    Kataoka, K.6
  • 189
    • 0001121655 scopus 로고    scopus 로고
    • Lactose-poly(ethylene glycol)-grafted poly-L-lysine as hepatoma cell-tapgeted gene carrier
    • Choi YH, Liu F, Park JS and Kim SW (1998) Lactose-poly(ethylene glycol)-grafted poly-L-lysine as hepatoma cell-tapgeted gene carrier. Bioconjug Chem 9:708-718.
    • (1998) Bioconjug Chem , vol.9 , pp. 708-718
    • Choi, Y.H.1    Liu, F.2    Park, J.S.3    Kim, S.W.4
  • 190
    • 0033199351 scopus 로고    scopus 로고
    • Polyion complex micelles with protein-modified corona for receptor-mediated delivery of oligonucleotides into cells
    • Vinogradov S, Batrakova E, Li S and Kabanov A (1999) Polyion complex micelles with protein-modified corona for receptor-mediated delivery of oligonucleotides into cells. Bioconjug Chem 10:851-860.
    • (1999) Bioconjug Chem , vol.10 , pp. 851-860
    • Vinogradov, S.1    Batrakova, E.2    Li, S.3    Kabanov, A.4
  • 191
    • 0036730299 scopus 로고    scopus 로고
    • Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo
    • Ward CM, Pechar M, Oupicky D, Ulbrich K and Seymour LW (2002) Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo. J Gene Med 4:536-547.
    • (2002) J Gene Med , vol.4 , pp. 536-547
    • Ward, C.M.1    Pechar, M.2    Oupicky, D.3    Ulbrich, K.4    Seymour, L.W.5
  • 194
    • 8844236162 scopus 로고    scopus 로고
    • Polyethyleneimine grafted with pluronic P85 enhances Ku86 antisense delivery and the ionizing radiation treatment efficacy in vivo
    • Belenkov AI, Alakhov VY, Kabanov AV, Vinogradov SV, Panasci LC, Monia BP and Chow TY (2004) Polyethyleneimine grafted with pluronic P85 enhances Ku86 antisense delivery and the ionizing radiation treatment efficacy in vivo. Gene Ther 11:1665-1672.
    • (2004) Gene Ther , vol.11 , pp. 1665-1672
    • Belenkov, A.I.1    Alakhov, V.Y.2    Kabanov, A.V.3    Vinogradov, S.V.4    Panasci, L.C.5    Monia, B.P.6    Chow, T.Y.7
  • 195
    • 0025343062 scopus 로고
    • Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
    • Yokoyama M, Miyauchi M, Yamada N, Okano T, Sakurai Y, Kataoka K and Inoue S (1990) Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. Cancer Res 50:1693-1700.
    • (1990) Cancer Res , vol.50 , pp. 1693-1700
    • Yokoyama, M.1    Miyauchi, M.2    Yamada, N.3    Okano, T.4    Sakurai, Y.5    Kataoka, K.6    Inoue, S.7
  • 197
    • 1942470679 scopus 로고    scopus 로고
    • Phase I dose escalation and pharmacokinetic study of pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer
    • Danson S, Ferry D, Alakhov V, Margison J, Kerr D, Jowle D, Brampton M, Halbert G and Ranson M (2004) Phase I dose escalation and pharmacokinetic study of pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer. Br J Cancer 90:2085-2091.
    • (2004) Br J Cancer , vol.90 , pp. 2085-2091
    • Danson, S.1    Ferry, D.2    Alakhov, V.3    Margison, J.4    Kerr, D.5    Jowle, D.6    Brampton, M.7    Halbert, G.8    Ranson, M.9
  • 198
    • 21744448393 scopus 로고    scopus 로고
    • A phase II, window study of SP1049C as first-line therapy in inoperable metastatic adenocarcinoma of the oesophagus
    • Vol. Abstract No: 4195
    • Valle JW, Lawrance J, Brewer J, Clayton A, Corrie P, Alakhov V and Ranson M (2004) A phase II, window study of SP1049C as first-line therapy in inoperable metastatic adenocarcinoma of the oesophagus. 2004 ASCO Annual Meeting Vol. Abstract No: 4195.
    • (2004) 2004 ASCO Annual Meeting
    • Valle, J.W.1    Lawrance, J.2    Brewer, J.3    Clayton, A.4    Corrie, P.5    Alakhov, V.6    Ranson, M.7
  • 199
    • 2542559832 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies
    • Kim TY, Kim DW, Chung JY, Shin SG, Kim SC, Heo DS, Kim NK and Bang YJ (2004) Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies. Clin Cancer Res 10:3708-3716.
    • (2004) Clin Cancer Res , vol.10 , pp. 3708-3716
    • Kim, T.Y.1    Kim, D.W.2    Chung, J.Y.3    Shin, S.G.4    Kim, S.C.5    Heo, D.S.6    Kim, N.K.7    Bang, Y.J.8


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