Reduction of fibronectin expression by intravitreal administration of antisense oligonucleotides

Nature Biotechnology

Volumn 17, Issue 5, 1999, Pages 476-479

  Roy, Sayon ^a   Zhang, Kathy ^a   Roth, Timothy ^b   Vinogradov, Sergei ^c   Kao, Richard S ^a   Kabanov, Alexander ^c  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Antisense oligonucleotides; Basement membrane; Block copolymer; Gene therapy

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; FIBRONECTIN; PHOSPHOROTHIOIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIABETIC RETINOPATHY; FLUORESCENCE ANALYSIS; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE THERAPY; IMMUNOPRECIPITATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; RAT; RETINA; TISSUE DISTRIBUTION; VITREOUS BODY;

ANIMALS; DOWN-REGULATION; DRUG DELIVERY SYSTEMS; FIBRONECTINS; MICROCIRCULATION; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; OLIGONUCLEOTIDES, ANTISENSE; POLYETHYLENE GLYCOLS; POLYMERS; RATS; RETINA; RETINAL VESSELS; SPERMINE; THIONUCLEOTIDES; VITREOUS BODY;

ANIMALIA;

EID: 0032937539     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/8654     Document Type: Article

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