Fundamental relationships between the composition of pluronic block copolymers and their hypersensitization effect in MDR cancer cells

Pharmaceutical Research

Volumn 16, Issue 9, 1999, Pages 1373-1379

  Batrakova, Elena ^a   Lee, Shengmin ^b   Li, Shu ^a   Venne, Annie ^b   Alakhov, Valery ^b   Kabanov, Alexander ^a  

^a NEBRASKA MEDICAL CENTER   (United States)

^b INRS INSTITUT ARMAND FRAPPIER   (Canada)

Author keywords

Block copolymers; Doxorubicin; Hypersensitization; Multidrug resistance; Pluronic; Rhodamine

Indexed keywords

ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; COPOLYMER; DOXORUBICIN; ETHYLENE OXIDE; GLYCOPROTEIN P; POLOXAMER; PROPYLENE OXIDE; RHODAMINE 123;

ANIMAL CELL; ARTICLE; CANCER CELL; CHO CELL; CONCENTRATION RESPONSE; CYTOTOXICITY; HUMAN; HUMAN CELL; HYDROPHOBICITY; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION;

ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CARCINOMA, SQUAMOUS CELL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; EXCIPIENTS; FLUORESCENT DYES; HUMANS; MOLECULAR WEIGHT; P-GLYCOPROTEIN; POLOXAMER; RHODAMINE 123; TUMOR CELLS, CULTURED; WATER;

EID: 0032862767     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018942823676     Document Type: Article

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