-
1
-
-
0017388651
-
Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase
-
Abchowski, A., McCoy, J.R., Palczuk, N.C., van Es, T. and Davis, F.F. (1977) Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase. J. Biol. Chem., 252, 3582-3586.
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 3582-3586
-
-
Abchowski, A.1
McCoy, J.R.2
Palczuk, N.C.3
Van Es, T.4
Davis, F.F.5
-
2
-
-
0022651231
-
Disposition kinetics of adriamycin, adriamycinol and their 7-deoxyglycones in AKR mice bearing a sub-cutaneously growing ridgway osteogenic sarcoma (ROS)
-
Cummings, J., Merry, S. and Willmott, N. (1986) Disposition kinetics of adriamycin, adriamycinol and their 7-deoxyglycones in AKR mice bearing a sub-cutaneously growing ridgway osteogenic sarcoma (ROS). Eur. J. Cancer Clin. Oncol., 22, 451-460.
-
(1986)
Eur. J. Cancer Clin. Oncol.
, vol.22
, pp. 451-460
-
-
Cummings, J.1
Merry, S.2
Willmott, N.3
-
3
-
-
0025305843
-
Sinusoidal endothelial cells of the liver: Fine structure and function in relation to age
-
De Leeuw, A.M., Brouwer, A. and Knook, D.L. (1990) Sinusoidal endothelial cells of the liver: Fine structure and function in relation to age. J. Electron Microscopy Technique, 14, 218-236.
-
(1990)
J. Electron Microscopy Technique
, vol.14
, pp. 218-236
-
-
De Leeuw, A.M.1
Brouwer, A.2
Knook, D.L.3
-
4
-
-
0029004025
-
Vascular permeability factor vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak, H.F., Brown, L.F., Detmar, M. and Dvorak, A.M. (1995) Vascular permeability factor vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am. J. Pathol., 146, 1029-1039.
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
Dvorak, A.M.4
-
5
-
-
0030484881
-
The role of polymer conjugates in the diagnosis and treatment of cancer
-
Duncan, R., Dimitrijevic, S. and Evagorou, E.G. (1996) The role of polymer conjugates in the diagnosis and treatment of cancer. S. T. P. Pharma. Sci., 6, 237-263.
-
(1996)
S. T. P. Pharma. Sci.
, vol.6
, pp. 237-263
-
-
Duncan, R.1
Dimitrijevic, S.2
Evagorou, E.G.3
-
6
-
-
0026718957
-
Selective in vivo localization of daunorubicin small unilamellar vesicles in solid tumors
-
Forssen, E.A., Coulter, D.M. and Proffitt, R.T. (1992) Selective in vivo localization of daunorubicin small unilamellar vesicles in solid tumors. Cancer Res., 52, 3255-3261.
-
(1992)
Cancer Res.
, vol.52
, pp. 3255-3261
-
-
Forssen, E.A.1
Coulter, D.M.2
Proffitt, R.T.3
-
7
-
-
0025162391
-
Effect of liposome composition and other factors on the targeting of liposomes to experimental tumors: Biodistribution and imaging studies
-
Gabizon, A., Price, D.C., Huberty, J., Bresalier, R.S. and Papahadjopoulos, D. (1990) Effect of liposome composition and other factors on the targeting of liposomes to experimental tumors: Biodistribution and imaging studies. Cancer Res., 50, 6371-6378.
-
(1990)
Cancer Res.
, vol.50
, pp. 6371-6378
-
-
Gabizon, A.1
Price, D.C.2
Huberty, J.3
Bresalier, R.S.4
Papahadjopoulos, D.5
-
8
-
-
0027050420
-
Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon tumor
-
Huang, S.K., Mayhew, E., Gilani, S., Lasic, D.D., Martin, F.J. and Papahadjopoulos, D. (1992) Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon tumor. Cancer Res., 52, 6774-6781.
-
(1992)
Cancer Res.
, vol.52
, pp. 6774-6781
-
-
Huang, S.K.1
Mayhew, E.2
Gilani, S.3
Lasic, D.D.4
Martin, F.J.5
Papahadjopoulos, D.6
-
9
-
-
0026699057
-
A new class of drug carriers: Micelles of poly(oxyethylene)-poly(oxypropylene) block copolymers as microcontainers for drug targeting from blood in brain
-
Kabanov, A.V., Batrakova, E.V., Melik-Nubarov, Fedoseev, N.A., Dorodnich, T.Y., Alakhov, V.Y., Chekhonin, V.P., Nazarova, I.R. and Kabanov, V.A.A. (1992) A new class of drug carriers: Micelles of poly(oxyethylene)-poly(oxypropylene) block copolymers as microcontainers for drug targeting from blood in brain. J. Contr. Rel., 22, 141-158.
-
(1992)
J. Contr. Rel.
, vol.22
, pp. 141-158
-
-
Kabanov, A.V.1
Batrakova, E.V.2
Melik-Nubarov3
Fedoseev, N.A.4
Dorodnich, T.Y.5
Alakhov, V.Y.6
Chekhonin, V.P.7
Nazarova, I.R.8
Kabanov, V.A.A.9
-
10
-
-
0001365675
-
Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine meth A sarcoma model
-
Katre, N.V., Knauf, M.J. and Laird, W.J. (1987) Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model. Proc. Natl. Acad. Sci. (USA). 84, 1487-1491.
-
(1987)
Proc. Natl. Acad. Sci. (USA)
, vol.84
, pp. 1487-1491
-
-
Katre, N.V.1
Knauf, M.J.2
Laird, W.J.3
-
11
-
-
0026459937
-
Pathways of macromolecular tracer transport across venules and small veins: Structural basis for the hyperpermeability of tumor blood vessels
-
Kohn, S., Nagy, J.A., Dvorak, H.F. and Dvorak, A.M. (1992) Pathways of macromolecular tracer transport across venules and small veins: Structural basis for the hyperpermeability of tumor blood vessels. Lab. Invest., 67, 596-607.
-
(1992)
Lab. Invest.
, vol.67
, pp. 596-607
-
-
Kohn, S.1
Nagy, J.A.2
Dvorak, H.F.3
Dvorak, A.M.4
-
12
-
-
0001288057
-
Polymers containing enzymatically degradable bonds, I. Chymotrypsin catalysed hydrolysis of p-nitroanilides of phenylalanine and tyrosine attached to side-chains of copolymers of N-(2-hydroxypropyl)methacrylamide
-
Kopecek, J., Rejmanova, P. and Chytry, V. (1981) Polymers containing enzymatically degradable bonds, I. Chymotrypsin catalysed hydrolysis of p-nitroanilides of phenylalanine and tyrosine attached to side-chains of copolymers of N-(2-hydroxypropyl)methacrylamide. Makromol. Chem., 182, 799-801.
-
(1981)
Makromol. Chem.
, vol.182
, pp. 799-801
-
-
Kopecek, J.1
Rejmanova, P.2
Chytry, V.3
-
13
-
-
0027282319
-
Biodistribution of micelle-forming polymer drug conjugates
-
Kwon, G.S., Yokoyama, M., Okano, T., Sakurai, S. and Kataoka, K. (1993) Biodistribution of micelle-forming polymer drug conjugates. Pharm. Res., 10, 970-974.
-
(1993)
Pharm. Res.
, vol.10
, pp. 970-974
-
-
Kwon, G.S.1
Yokoyama, M.2
Okano, T.3
Sakurai, S.4
Kataoka, K.5
-
14
-
-
0028346185
-
Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer adriamycin conjugates
-
Kwon, G.S., Yokoyama, M., Okano, T., Sakurai, S. and Kataoka, K. (1994a) Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer adriamycin conjugates. J. Contr. Rel., 29, 17-23.
-
(1994)
J. Contr. Rel.
, vol.29
, pp. 17-23
-
-
Kwon, G.S.1
Yokoyama, M.2
Okano, T.3
Sakurai, S.4
Kataoka, K.5
-
15
-
-
0028769164
-
Block copolymer micelles as vehicles for hydrophobic drugs
-
Kwon, G.S., Naito, M., Kataoka, K., Yokoyama, M., Sakurai, Y. and Okano, T. (1994b) Block copolymer micelles as vehicles for hydrophobic drugs. Colloids and Surfaces B: Biointerfaces, 2, 429-434.
-
(1994)
Colloids and Surfaces B: Biointerfaces
, vol.2
, pp. 429-434
-
-
Kwon, G.S.1
Naito, M.2
Kataoka, K.3
Yokoyama, M.4
Sakurai, Y.5
Okano, T.6
-
16
-
-
0028897485
-
Physical entrapment of doxorubicin in AB block copolymer micelles
-
Kwon, G.S., Naito, M., Kataoka, K., Yokoyama, M., Okano, T. and Sakurai, Y. (1995) Physical entrapment of doxorubicin in AB block copolymer micelles. Pharm. Res., 12, 192-195.
-
(1995)
Pharm. Res.
, vol.12
, pp. 192-195
-
-
Kwon, G.S.1
Naito, M.2
Kataoka, K.3
Yokoyama, M.4
Okano, T.5
Sakurai, Y.6
-
17
-
-
0030801878
-
Block copolymer micelles for drug delivery: Loading and release of doxorubicin
-
Kwon, G.S., Naito, M., Yokoyama, M., Okano, T., Sakurai, Y. and Kataoka, K. (1997) Block copolymer micelles for drug delivery: Loading and release of doxorubicin. J. Contr. Rel., 48, 195-201.
-
(1997)
J. Contr. Rel.
, vol.48
, pp. 195-201
-
-
Kwon, G.S.1
Naito, M.2
Yokoyama, M.3
Okano, T.4
Sakurai, Y.5
Kataoka, K.6
-
18
-
-
0025934604
-
Sterically stabilized liposomes: A hypothesis on the molecular origin of the extended circulation times
-
Lasic, D.D., Martin, F.J., Gabizon, A., Huang, S.K. and Papahadjopoulos, D. (1991) Sterically stabilized liposomes: A hypothesis on the molecular origin of the extended circulation times. Biochim. Biophys. Acta, 1070, 187-192.
-
(1991)
Biochim. Biophys. Acta
, vol.1070
, pp. 187-192
-
-
Lasic, D.D.1
Martin, F.J.2
Gabizon, A.3
Huang, S.K.4
Papahadjopoulos, D.5
-
19
-
-
0028055226
-
Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes
-
Litzinger, D.C., Buiting, A.M.J., van Roojen, N. and Huang, L. (1994) Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes. Biochim. Biophys. Acta, 1190, 99-107.
-
(1994)
Biochim. Biophys. Acta
, vol.1190
, pp. 99-107
-
-
Litzinger, D.C.1
Buiting, A.M.J.2
Van Roojen, N.3
Huang, L.4
-
20
-
-
0026926609
-
Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo
-
Maeda, H., Seymour, L.W. and Miyamoto, Y. (1992) Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo. Bioconjugate Chem., 3, 351-362.
-
(1992)
Bioconjugate Chem.
, vol.3
, pp. 351-362
-
-
Maeda, H.1
Seymour, L.W.2
Miyamoto, Y.3
-
21
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Matsumura, Y. and Maeda, H. (1986) A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res., 46, 6387-6392.
-
(1986)
Cancer Res.
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
22
-
-
0024505811
-
Lack of comparability between binding of monoclonal antibodies to melanoma cells in vitro and localization in vivo
-
McCready, D.R., Balch, C.M., Fidler, I.J. and Murray, J.L. (1989) Lack of comparability between binding of monoclonal antibodies to melanoma cells in vitro and localization in vivo. J. Natl. Cancer. Inst., 81, 682-687.
-
(1989)
J. Natl. Cancer. Inst.
, vol.81
, pp. 682-687
-
-
McCready, D.R.1
Balch, C.M.2
Fidler, I.J.3
Murray, J.L.4
-
23
-
-
0029925934
-
Treatment of advanced tumors with immunotoxin LMB-1: An antibody linked pseudomonas exotoxin
-
Pai, L.H., Wittes, R., Setser, A., Willingham, M.C. and Pastan, I. (1996) Treatment of advanced tumors with immunotoxin LMB-1: An antibody linked Pseudomonas exotoxin. Nature Medicine, 2, 350-353.
-
(1996)
Nature Medicine
, vol.2
, pp. 350-353
-
-
Pai, L.H.1
Wittes, R.2
Setser, A.3
Willingham, M.C.4
Pastan, I.5
-
24
-
-
0346551010
-
Polymer conjugates with anticancer activity
-
Putnam, D. and Kopecek, J. (1995) Polymer conjugates with anticancer activity. Adv. Polym. Sci., 122, 55-123.
-
(1995)
Adv. Polym. Sci.
, vol.122
, pp. 55-123
-
-
Putnam, D.1
Kopecek, J.2
-
25
-
-
0027112202
-
New macromolecular carriers for drugs. I. Preparation and characterization of poly(oxyethylene-b-isoprene-b-oxyethylene) block copolymer aggregates
-
Rolland, A., O'mullane, J., Goddard, P., Brookman, L. and Petrak, K. (1992) New macromolecular carriers for drugs. I. Preparation and characterization of poly(oxyethylene-b-isoprene-b-oxyethylene) block copolymer aggregates. J. Appl. Polym. Sci., 44, 1195-1203.
-
(1992)
J. Appl. Polym. Sci.
, vol.44
, pp. 1195-1203
-
-
Rolland, A.1
O'mullane, J.2
Goddard, P.3
Brookman, L.4
Petrak, K.5
-
26
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
Senger, D.R., Galli, S.J., Dvorak, A.M., Perruzzi, C.A., Harvey, V.S. and Dvorak, H.F. (1983) Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science, 219, 983-985.
-
(1983)
Science
, vol.219
, pp. 983-985
-
-
Senger, D.R.1
Galli, S.J.2
Dvorak, A.M.3
Perruzzi, C.A.4
Harvey, V.S.5
Dvorak, H.F.6
-
27
-
-
0029039418
-
Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier
-
Seymour, L.W., Miyamoto, Y., Maeda, H., Brereton, M., Strohalm, J., Ulbrich, K. and Duncan, R. (1995) Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier. Eur. J. Cancer, 31A, 766-770.
-
(1995)
Eur. J. Cancer
, vol.31 A
, pp. 766-770
-
-
Seymour, L.W.1
Miyamoto, Y.2
Maeda, H.3
Brereton, M.4
Strohalm, J.5
Ulbrich, K.6
Duncan, R.7
-
28
-
-
0029838250
-
Review: Liposomal doxorubicin
-
Tardi, P.G., Boman, N.L. and Cullis, P.R. (1996) Review: Liposomal doxorubicin. J. Drug Targeting, 4, 129-140.
-
(1996)
J. Drug Targeting
, vol.4
, pp. 129-140
-
-
Tardi, P.G.1
Boman, N.L.2
Cullis, P.R.3
-
29
-
-
0343718389
-
(Paso)physiology and the temporal and spatial aspects of drug delivery
-
Tomlinson, E. and Davis, S.S. (Eds.) Wiley & Sons Ltd.
-
Tomlinson, E. (1986) (Paso)physiology and the temporal and spatial aspects of drug delivery. In Tomlinson, E. and Davis, S.S. (Eds.) Site-Specific Drug Delivery (Wiley & Sons Ltd.), pp. 1-26.
-
(1986)
Site-specific Drug Delivery
, pp. 1-26
-
-
Tomlinson, E.1
-
30
-
-
0027218284
-
Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates
-
Trail, P.A., Wilner, D., Lasch, S.J., Henderson, A.J., Hofstead, H., Casazza, A.M., Firestone, R.A., Hellström, I. and Hellström, K.E. (1993) Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates. Science, 261, 212-215.
-
(1993)
Science
, vol.261
, pp. 212-215
-
-
Trail, P.A.1
Wilner, D.2
Lasch, S.J.3
Henderson, A.J.4
Hofstead, H.5
Casazza, A.M.6
Firestone, R.A.7
Hellström, I.8
Hellström, K.E.9
-
31
-
-
0000583632
-
Direct determinations of plasma, cell, and organ-blood volumes in normal and hypervolemic mice
-
Wish, L., Furth, J. and Storey, R.H. (1950) Direct determinations of plasma, cell, and organ-blood volumes in normal and hypervolemic mice. Proc. Soc. Exp. Biol. And Med., 74, 644-648.
-
(1950)
Proc. Soc. Exp. Biol. And Med.
, vol.74
, pp. 644-648
-
-
Wish, L.1
Furth, J.2
Storey, R.H.3
-
33
-
-
0015348503
-
Comparative pharamacokinetics of daunomycin and adriamycin in several animal species
-
Yesair, D.W., Schwartzbach, E., Shunk, D., Denine, E.P. and Asbell, M.A. (1972) Comparative pharamacokinetics of daunomycin and adriamycin in several animal species. Cancer Res., 32, 1177-1183.
-
(1972)
Cancer Res.
, vol.32
, pp. 1177-1183
-
-
Yesair, D.W.1
Schwartzbach, E.2
Shunk, D.3
Denine, E.P.4
Asbell, M.A.5
-
34
-
-
0025343062
-
Characterization and anticancer activity of the micelle-forming polymeric anticancer drug doxorubicin-conjugated poly(ethylene glycol)-poly (aspartic acid) block copolymer
-
Yokoyama, M., Miyauchi, M., Yamada, N., Okano, T., Sakurai, Y., Kataoka, K. and Inoue, S. (1990) Characterization and anticancer activity of the micelle-forming polymeric anticancer drug doxorubicin-conjugated poly(ethylene glycol)-poly (aspartic acid) block copolymer. Cancer Res., 50, 1693-1700.
-
(1990)
Cancer Res.
, vol.50
, pp. 1693-1700
-
-
Yokoyama, M.1
Miyauchi, M.2
Yamada, N.3
Okano, T.4
Sakurai, Y.5
Kataoka, K.6
Inoue, S.7
-
35
-
-
0025874282
-
Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood
-
Yokoyama, M., Okano, T., Sakurai, Y., Ekimoto, H., Shibazaki, C. and Kataoka, K. (1991) Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood. Cancer Res., 51, 3229-3236.
-
(1991)
Cancer Res.
, vol.51
, pp. 3229-3236
-
-
Yokoyama, M.1
Okano, T.2
Sakurai, Y.3
Ekimoto, H.4
Shibazaki, C.5
Kataoka, K.6
-
36
-
-
0002596448
-
Composition-dependent in vivo antitumor activity of doxorubicin-conjugated polymeric micelle against murine colon adenocarcinoma 26
-
Yokoyama, M., Kwon, G.S., Okano, T., Sakurai, Y., Ekimoto, H., Okamoto, K., Mashiba, H., Seto, T. and Kataoka, K. (1993) Composition-dependent in vivo antitumor activity of doxorubicin-conjugated polymeric micelle against murine colon adenocarcinoma 26. Drug Delivery, 1, 11-19.
-
(1993)
Drug Delivery
, vol.1
, pp. 11-19
-
-
Yokoyama, M.1
Kwon, G.S.2
Okano, T.3
Sakurai, Y.4
Ekimoto, H.5
Okamoto, K.6
Mashiba, H.7
Seto, T.8
Kataoka, K.9
-
37
-
-
0028135121
-
Improved synthesis of doxorubicin-conjugated poly(ethylene oxide)-poly(aspartic acid) block copolymer and formation of unimodal micellar structure with controlled amount of physically entrapped doxorubicin
-
Yokoyama, M., Okano, T., Sakurai, Y. and Kataoka, K. (1994) Improved synthesis of doxorubicin-conjugated poly(ethylene oxide)-poly(aspartic acid) block copolymer and formation of unimodal micellar structure with controlled amount of physically entrapped doxorubicin. J. Contr. Rel., 32, 269-277.
-
(1994)
J. Contr. Rel.
, vol.32
, pp. 269-277
-
-
Yokoyama, M.1
Okano, T.2
Sakurai, Y.3
Kataoka, K.4
-
38
-
-
0030234981
-
Targetable drug carriers: Present status and a future perspective
-
Yokoyama, M. and Okano, T. (1997) Targetable drug carriers: Present status and a future perspective. Adv. Drug Delivery Rev., 21, 77-80.
-
(1997)
Adv. Drug Delivery Rev.
, vol.21
, pp. 77-80
-
-
Yokoyama, M.1
Okano, T.2
-
39
-
-
0032472352
-
Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and thier design for in vivo delivery to a solid tumor
-
Yokoyama, M., Fukushima, S., Vehara, R., Okamoto, K., Kataoka, K., Sakurai, Y. and Okano, T. (1998) Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and thier design for in vivo delivery to a solid tumor. J. Contr. Rel., 50, 79-92.
-
(1998)
J. Contr. Rel.
, vol.50
, pp. 79-92
-
-
Yokoyama, M.1
Fukushima, S.2
Vehara, R.3
Okamoto, K.4
Kataoka, K.5
Sakurai, Y.6
Okano, T.7
|