Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs

Bioconjugate Chemistry

Volumn 11, Issue 6, 2000, Pages 910-917

  Kojima, C ^a   Kono, K ^a   Maruyama, K ^b   Takagishi, T ^a  

^a Osaka Prefecture University   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCOMPATIBILITY; CHAINS; CHLORINE COMPOUNDS; CONTROLLED DRUG DELIVERY; DENDRIMERS; DRUG PRODUCTS; ETHYLENE GLYCOL; IONIC STRENGTH; MOLECULAR WEIGHT; MOLECULES; POLYOLS; TARGETED DRUG DELIVERY;

ADRIAMYCIN; ANTICANCER DRUG; AVERAGE MOLECULAR WEIGHT; BIOCOMPATIBLE SURFACES; CHAIN-ENDS; DRUG CARRIER; FOURTH GENERATION; MONOMETHYL ETHERS; POLYAMIDOAMINE DENDRIMERS; THIRD GENERATION;

POLYETHYLENE GLYCOLS;

EID: 0033657796     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0000583     Document Type: Article

References (37)

1. Starburst dendrimers: Molecular-level control of size, shape, surface chemistry, topology, and flexibility from atoms to macroscopic matter
2. Functional polymers and dendrimers: Reactivity, molecular architecture, and interfacial energy
3. Unusual macromolecular architectures: The convergent growth approach to dendritic polyesters and novel block copolymers
4. Encapsulation of guest molecules into a dendritic box
5. Unimolecular micelles
6. Poly(propylene imine) dendrimers as pH-sensitive controlled release systems
7. Designing dendrimers for drug delivery
8. In vitro release of 5-fluorouracil with cyclic core dendritic polymer
9. Design of dendritic macromolecules containing folate or methotrexate residues
10. Unimolecular micelles and globular amphiphiles: Dendritic macromolecules as novel recyclable solubilization agents
11. The synthesis of water soluble dendrimers, and their application as possible drug delivery systems
12. The dendritic box: Shape-selective liberation of encapsulated guests
13. Preliminary biological evaluation of polyamidoamine (PAM-AM) Starburst dendrimers
14. 125I-labeled polyamidoamine dendrimers in vivo
15. Alteration of immunological properties of bovine serum albumin by covalent attachment of poly(ethylene glycol)
16. Effect of covalent attachment of poly-(ethylene glycol) on immunogenicity and circulating life of bovine liver catalase
17. Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood
18. Amphipathic poly(ethylene glycol)s effectively prolong the circulation time of liposomes
19. Liposomes for the sustained drug release in vivo
20. Sterically stabilized liposomes
21. The stealth liposome: A prototypical biomaterial
22. Gadolinium (III) DO3A macrocycles and poly(ethylene glycol) coupled to dendrimers. Effect of molecular weight on physical and biological properties of macromolecular magnetic resonance imaging contrast agents
23. Water-soluble dendritic unimolecular micelles: Their potential as drug delivery agents
24. Water-soluble dendrimer-poly(ethylene glycol) starlike conjugates as potential drug carriers
25. Dendrimers with both hydrophilic and hydrophobic chains at every end
26. The localization of guests in water-soluble oligoethyleneoxy-modified poly(propylene imine) dendrimers
27. Preparation of polymers with controlled molecular architecture. A new convergent approach to dendritic macromolecules
28. A new universal GPC calibration method
29. Das problem der membran bei osmotischen messungen an hochpolymeren. III
30. Block copolymer micelles for drug delivery: Loading and release of doxorubicin
31. Extraction of daunorubicin and doxorubicin and their hydroxyl metabolites: Self-association in aqueous solution
32. The pharmacology of methotrexate
33. Starburst dendrimers. 5. Molecular shape control