Synthetic macromolecular drug carriers: Biodistribution of poly[(N-2-hydroxypropyl)methacrylamide] Copolymers and their accumulation in solid rat tumors

PDA Journal of Pharmaceutical Science and Technology

Volumn 55, Issue 3, 2001, Pages 191-201

  Kissel, M ^a   Peschke, P ^a   Subr, V ^a   Ulbrich, K ^a   Schuhmacher, J ^a   Debus, J ^a   Friedrich, E ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Drug targeting; EPR effect; Gamma camera imaging; HPMA; Poly (N (2 hydroxypropyl)methacrylamide ; Tumor uptake

Indexed keywords

COPOLYMER; DRUG CARRIER; POLY[(N 2 HYDROXYPROPYL)METHACRYLAMIDE] COPOLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG PENETRATION; DRUG RETENTION; DRUG TUMOR LEVEL; ISOTOPE LABELING; MOLECULAR WEIGHT; NONHUMAN; PROSTATE CARCINOMA; RAT; SCINTIGRAPHY; SOLID TUMOR; TUMOR MODEL;

ADENOCARCINOMA; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CARRIERS; FLUORESCEIN-5-ISOTHIOCYANATE; MALE; METABOLIC CLEARANCE RATE; METHACRYLATES; NEOPLASMS, EXPERIMENTAL; PROSTATIC NEOPLASMS; RATS; TISSUE DISTRIBUTION;

EID: 0034989921     PISSN: 10797440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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