Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion

British Journal of Cancer

Volumn 85, Issue 12, 2001, Pages 1987-1997

  Batrakova, E V ^a   Li, S ^a   Elmquist, W F ^a   Miller, D W ^a   Alakhov, V Y ^b   Kabanov, A V ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b Supratek Pharma Inc   (Canada)

Author keywords

ATP; Doxorubicin; MDR; Pluronic; Sensitisation

Indexed keywords

ADENOSINE TRIPHOSPHATE; COPOLYMER; DOXORUBICIN; GLYCOPROTEIN P; PLURONIC P85; POLOXAMER; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL SPECIFICITY; CELL STRAIN CACO 2; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MICROVASCULATURE; MYOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIZATION; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT, ACTIVE; BRAIN; CAPILLARIES; CATTLE; CELL LINE; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENDOTHELIUM, VASCULAR; ENERGY METABOLISM; HUMANS; KB CELLS; KINETICS; NEOPLASM PROTEINS; NEOPLASMS; P-GLYCOPROTEIN; POLOXALENE; SWINE; TUMOR CELLS, CULTURED; TUMOR STEM CELLS; UMBILICAL VEINS;

EID: 0035556313     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2001.2165     Document Type: Article

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