In vivo evaluation of polymeric micellar paclitaxel formulation: Toxicity and efficacy

Journal of Controlled Release

Volumn 72, Issue 1-3, 2001, Pages 191-202

  Kim, Sung Chul ^a   Kim, Dong Wook ^a   Shim, Yong Ho ^a   Bang, Joon Seok ^a   Oh, Hun Seung ^a   Kim, Sung Wan ^b   Seo, Min Hyo ^a  

^a Samyang Corporation   (South Korea)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

Antitumor efficacy; Biodistribution; Micellar paclitaxel; mPEG PDLLA; Paclitaxel (Taxol )

Indexed keywords

AMPHOPHILE; COPOLYMER; GENEXOL PM; MONOMETHOXY MACROGOL POLYLACTIDE COPOLYMER; PACLITAXEL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BIODEGRADATION; BREAST CARCINOMA; CANCER TRANSPLANTATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; DRUG TISSUE LEVEL; FEMALE; IN VIVO STUDY; LETHAL DOSE; MALE; MAXIMUM TOLERATED DOSE; MELANOMA; MICELLE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUDE MOUSE; OVARY CARCINOMA; PRIORITY JOURNAL; RAT; STRAIN DIFFERENCE; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DRUG CARRIERS; DRUG COMPOUNDING; FEMALE; HUMANS; LACTIC ACID; LETHAL DOSE 50; MALE; MICE; MICE, NUDE; MICELLES; PACLITAXEL; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED;

EID: 0035858296     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00275-9     Document Type: Article

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