Doxorubicin-loaded poly(ethylene glycol)-poly(β-benzyl-L-aspartate) copolymer micelles: Their pharmaceutical characteristics and biological significance

Journal of Controlled Release

Volumn 64, Issue 1-3, 2000, Pages 143-153

  Kataoka, Kazunori ^a   Matsumoto, Tsuyoshi ^b   Yokoyama, Masayuki ^c   Okano, Teruo ^c   Sakurai, Yasuhisa ^c   Fukushima, Shigeto ^d   Okamoto, Kazuya ^d   Kwon, Glen S ^e  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^d NIPPON KAYAKU CO LTD   (Japan)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Doxorubicin; Drug carrier; Long circulation; Poly(ethylene glycol) poly( benzyl L aspartate) block copolymer; Polymer micelle

Indexed keywords

CARBON 14; COPOLYMER; DIMER; DOXORUBICIN; DRUG CARRIER; MACROGOL; POLY(BETA BENZYL LEVO ASPARTATE); UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; CANCER GRAFT; COLON ADENOCARCINOMA; CONFERENCE PAPER; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG RELEASE; DRUG SOLUBILITY; EMULSION; FEMALE; MALE; MICELLE; MOUSE; NONHUMAN; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RETICULOENDOTHELIAL SYSTEM;

ADENOSARCOMA; ANIMALS; ANTINEOPLASTIC AGENTS; COLONIC NEOPLASMS; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EMULSIONS; HYDROGEN-ION CONCENTRATION; MALE; MICE; MICELLES; PARTICLE SIZE; PEPTIDES; POLYETHYLENE GLYCOLS; RETICULOENDOTHELIAL SYSTEM; SOLUBILITY; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0033980297     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(99)00133-9     Document Type: Conference Paper

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