메뉴 건너뛰기




Volumn 8, Issue 5, 1997, Pages 649-657

Interactions of pluronic block copolymers with brain microvessel endothelial cells: Evidence of two potential pathways for drug absorption

Author keywords

[No Author keywords available]

Indexed keywords

BLOCK COPOLYMERS; BLOOD VESSELS; CONTROLLED DRUG DELIVERY; CRITICAL MICELLE CONCENTRATION; CYTOLOGY; DRUG INTERACTIONS; GLYCOPROTEINS; MICELLES; TARGETED DRUG DELIVERY;

EID: 0031239096     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc970118d     Document Type: Article
Times cited : (160)

References (28)
  • 3
    • 0025343062 scopus 로고
    • Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
    • Yokoyama, M., Miyauchi, M., Yamada, N., Okano, T., Sakurai, Y., Kataoka, K., and Inoue, S. (1990) Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. Cancer Res. 50, 1693-1700.
    • (1990) Cancer Res. , vol.50 , pp. 1693-1700
    • Yokoyama, M.1    Miyauchi, M.2    Yamada, N.3    Okano, T.4    Sakurai, Y.5    Kataoka, K.6    Inoue, S.7
  • 5
    • 0000952093 scopus 로고    scopus 로고
    • Polylactide-poly(ethylene glycol) copolymers as drug delivery systems. 1. Characterization of water dispersible micelle-forming systems
    • Hagan, S. A., Coombes, G. A., Garnett, M. C., Dunn, S. E., Davies, M. C., Illum, L., Davis, S. S., Harding, S. E., Purkiss, S., and Gellert, P. R. (1996) Polylactide-poly(ethylene glycol) copolymers as drug delivery systems. 1. Characterization of water dispersible micelle-forming systems. Langmuir 12, 2153-2161.
    • (1996) Langmuir , vol.12 , pp. 2153-2161
    • Hagan, S.A.1    Coombes, G.A.2    Garnett, M.C.3    Dunn, S.E.4    Davies, M.C.5    Illum, L.6    Davis, S.S.7    Harding, S.E.8    Purkiss, S.9    Gellert, P.R.10
  • 6
    • 0002960925 scopus 로고    scopus 로고
    • Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poy(ethylene oxide)-poly(β-benzyl L-aspartate) block copolymer micelles
    • La, S. B., Okano, T., and Kataoka, K. (1996) Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poy(ethylene oxide)-poly(β-benzyl L-aspartate) block copolymer micelles. J. Pharm. Sci. 85, 91-95.
    • (1996) J. Pharm. Sci. , vol.85 , pp. 91-95
    • La, S.B.1    Okano, T.2    Kataoka, K.3
  • 8
    • 0026554050 scopus 로고
    • Pluronic micelles as a tool for low-molecular compound vector delivery into a cell: Effect of Staphylococcus aureus enterotoxin B on cell loading with micelle incorporated fluorescent dye
    • Kabanov, A. V., Slepnev, V. I., Kuznetsova, L. E., Batrakova, E. V., Alakhov, V. Yu., Melik-Nubarov, N. S., Sveshnikov, P. G., and Kabanov, V. A. (1992) Pluronic micelles as a tool for low-molecular compound vector delivery into a cell: effect of Staphylococcus aureus enterotoxin B on cell loading with micelle incorporated fluorescent dye. Biochem. Int. 26, 1035-1042.
    • (1992) Biochem. Int. , vol.26 , pp. 1035-1042
    • Kabanov, A.V.1    Slepnev, V.I.2    Kuznetsova, L.E.3    Batrakova, E.V.4    Alakhov, V.Yu.5    Melik-Nubarov, N.S.6    Sveshnikov, P.G.7    Kabanov, V.A.8
  • 9
    • 0030111359 scopus 로고    scopus 로고
    • Hypersensitization of multidrug resistant human ovarian carcinoma cells by Pluronic P85 block copolymer
    • Alakhov, V. Y., Moskaleva, E. Yu., Batrakova, E. V., and Kabanov, A. V. (1996) Hypersensitization of multidrug resistant human ovarian carcinoma cells by Pluronic P85 block copolymer. Bioconjugate Chem. 7, 209-216.
    • (1996) Bioconjugate Chem. , vol.7 , pp. 209-216
    • Alakhov, V.Y.1    Moskaleva, E.Yu.2    Batrakova, E.V.3    Kabanov, A.V.4
  • 10
    • 0029765581 scopus 로고    scopus 로고
    • Hypersensitizing effects of Pluronic L61 on cytotoxic activity, transport, and subcellular distribution of doxorubicin in multiple drug-resistant cells
    • Venne, A., Li, S., Mandeville, R., Kabanov, A. V., and Alakhov, V. Yu. (1996) Hypersensitizing effects of Pluronic L61 on cytotoxic activity, transport, and subcellular distribution of doxorubicin in multiple drug-resistant cells. Cancer Res. 56, 3626-3629.
    • (1996) Cancer Res. , vol.56 , pp. 3626-3629
    • Venne, A.1    Li, S.2    Mandeville, R.3    Kabanov, A.V.4    Alakhov, V.Yu.5
  • 12
    • 0027092617 scopus 로고
    • Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells
    • Hegmann, E. J., Bauer, H. C., and Kerbel, B. S. (1992) Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells. Cancer Res. 52, 6969-6975.
    • (1992) Cancer Res. , vol.52 , pp. 6969-6975
    • Hegmann, E.J.1    Bauer, H.C.2    Kerbel, B.S.3
  • 13
    • 0030604062 scopus 로고    scopus 로고
    • Use of rhodamine 123 to examine the functional activity of P-glycoprotein in primary cultured brain microvessel endothelial cell monolayers
    • Fontaine, M., Elmquist, W. F., and Miller, D. W. (1996) Use of rhodamine 123 to examine the functional activity of P-glycoprotein in primary cultured brain microvessel endothelial cell monolayers. Life Sci. 59, 1521-1531.
    • (1996) Life Sci. , vol.59 , pp. 1521-1531
    • Fontaine, M.1    Elmquist, W.F.2    Miller, D.W.3
  • 14
    • 0000953843 scopus 로고
    • Application of cultured bovine brain endothelial cells of the brain microvasiculature in the study of the blood-brain barrier
    • Miller, D. W., Audus, K. L., and Borchardt, R. T. (1992) Application of cultured bovine brain endothelial cells of the brain microvasiculature in the study of the blood-brain barrier. J. Tissue Cult. Methods 14, 217-224.
    • (1992) J. Tissue Cult. Methods , vol.14 , pp. 217-224
    • Miller, D.W.1    Audus, K.L.2    Borchardt, R.T.3
  • 15
    • 0029565014 scopus 로고
    • An in vitro model for endothelial cell permeability and assessment of monolayer multiplicity
    • Kazakoff, P. W., McGuire, T. R., Hoie, E. B., Cano, M., and Iversen, P. L. (1995) An in vitro model for endothelial cell permeability and assessment of monolayer multiplicity. In Vitro Cell. Dev. Biol. 31, 846-852.
    • (1995) In Vitro Cell. Dev. Biol. , vol.31 , pp. 846-852
    • Kazakoff, P.W.1    McGuire, T.R.2    Hoie, E.B.3    Cano, M.4    Iversen, P.L.5
  • 16
    • 0026425695 scopus 로고
    • Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug-resistant cell lines using laser-assisted confocal microscopy
    • Gervasoni, J. E., Fields, S. Z., Krishna, S., Baker, M. A., Rosado, M., Thuraisamy, K., Hindenburg, A. A., and Taub, R. N. (1991) Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug-resistant cell lines using laser-assisted confocal microscopy. Cancer Res. 51, 4955-4964.
    • (1991) Cancer Res. , vol.51 , pp. 4955-4964
    • Gervasoni, J.E.1    Fields, S.Z.2    Krishna, S.3    Baker, M.A.4    Rosado, M.5    Thuraisamy, K.6    Hindenburg, A.A.7    Taub, R.N.8
  • 17
    • 0025157023 scopus 로고
    • Fluid-phase endocytosis by primary cultures of bovine brain microvessel endothelial cell monolayers
    • Guillot, F. L., Audus, K. L., and Raub, T. J. (1990) Fluid-phase endocytosis by primary cultures of bovine brain microvessel endothelial cell monolayers. Microvascular Res. 39, 1-14.
    • (1990) Microvascular Res. , vol.39 , pp. 1-14
    • Guillot, F.L.1    Audus, K.L.2    Raub, T.J.3
  • 21
    • 0027936743 scopus 로고
    • Epoxide metabolite of quinine and inhibition of the multidrug resistance pump in human leukemic lymphoblasts
    • Wigler, P. W., Lyon, K. L., Patterson, F. K., Laloggia, A. J., Dia-Arauzo, H., Reddy, M. S., and Cook, J. M. (1994) Epoxide metabolite of quinine and inhibition of the multidrug resistance pump in human leukemic lymphoblasts. Mol. Pharmacol. 46, 563-567.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 563-567
    • Wigler, P.W.1    Lyon, K.L.2    Patterson, F.K.3    Laloggia, A.J.4    Dia-Arauzo, H.5    Reddy, M.S.6    Cook, J.M.7
  • 22
    • 0027508834 scopus 로고
    • Estradiol induction of rhodamine 123 efflux and multidrug resistance pump in rat pituitary tumor cells
    • Jancis, E. M., Carbone, R., Loechner, K. J., and Dannies, P. S. (1993) Estradiol induction of rhodamine 123 efflux and multidrug resistance pump in rat pituitary tumor cells. Mol. Pharmacol. 43, 51-56.
    • (1993) Mol. Pharmacol. , vol.43 , pp. 51-56
    • Jancis, E.M.1    Carbone, R.2    Loechner, K.J.3    Dannies, P.S.4
  • 23
    • 0029875543 scopus 로고    scopus 로고
    • The use of surfactants to enhance the permeability of peptides through Caco-2 cells by inhibition of an apically polarized efflux system
    • Nerurkar, M. M., Burton, P. S., and Borchardt, R. T. (1996) The use of surfactants to enhance the permeability of peptides through Caco-2 cells by inhibition of an apically polarized efflux system. Pharm. Res. 13, 528-534.
    • (1996) Pharm. Res. , vol.13 , pp. 528-534
    • Nerurkar, M.M.1    Burton, P.S.2    Borchardt, R.T.3
  • 24
    • 0029079452 scopus 로고
    • Reversal of multidrug resistance phenotype by surfactants : Relationship to membrane lipid fluidity
    • Dudeja, P. K., Anderson, K. M., Harris, J. S., Buckingham, L., and Coon, J. S. (1995) Reversal of multidrug resistance phenotype by surfactants : relationship to membrane lipid fluidity. Arch. Biochem. Biophys. 319, 309-315.
    • (1995) Arch. Biochem. Biophys. , vol.319 , pp. 309-315
    • Dudeja, P.K.1    Anderson, K.M.2    Harris, J.S.3    Buckingham, L.4    Coon, J.S.5
  • 25
    • 0027136158 scopus 로고
    • Effects of nonionic detergents on P-glycoprotein drug binding and reversal of multidrug resistance
    • Zordan-Nudo, T., Ling, V., Liu, Z., and Georges, E. (1993) Effects of nonionic detergents on P-glycoprotein drug binding and reversal of multidrug resistance. Cancer Res. 53, 5994-6000.
    • (1993) Cancer Res. , vol.53 , pp. 5994-6000
    • Zordan-Nudo, T.1    Ling, V.2    Liu, Z.3    Georges, E.4
  • 26
    • 0027683882 scopus 로고
    • Molecular modeling of micelle formation and solubilization in block copolymer micelles. 1. A self-consistent meanfield lattice theory
    • Hunter, P. N., Scheutjens, J. M. H. M., and Hatton, T. A. (1993) Molecular modeling of micelle formation and solubilization in block copolymer micelles. 1. A self-consistent meanfield lattice theory. Macromolecules 26, 5592-5601.
    • (1993) Macromolecules , vol.26 , pp. 5592-5601
    • Hunter, P.N.1    Scheutjens, J.M.H.M.2    Hatton, T.A.3
  • 28
    • 0029892497 scopus 로고    scopus 로고
    • P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
    • Schinkel, A. H., Wagenaar, E., Mol, C. A. A. M., and van Deemter, L. (1996) P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J. Clin. Invest. 97, 2517-2524.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2517-2524
    • Schinkel, A.H.1    Wagenaar, E.2    Mol, C.A.A.M.3    Van Deemter, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.