Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor

Journal of Controlled Release

Volumn 50, Issue 1-3, 1998, Pages 79-92

  Yokoyama, Masayuki ^a,d   Fukushima, Shigeto ^b   Uehara, Ryuji ^b   Okamoto, Kazuya ^b   Kataoka, Kazunori ^c,d   Sakurai, Yasuhisa ^a,d   Okano, Teruo ^a,d  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b NIPPON KAYAKU CO LTD   (Japan)

^c National Institute of Advanced Industrial Science and Technology   (Japan)

^d TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Adriamycin; Anticancer drug; Dimer; Polymeric micelles; Stability

Indexed keywords

COPOLYMER; DIMER; DOXORUBICIN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; COLON ADENOCARCINOMA; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG IDENTIFICATION; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOLID TUMOR;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; DOXORUBICIN; DRUG DELIVERY SYSTEMS; FEMALE; LEUKEMIA P388; MICE; MICELLES; NEOPLASMS, EXPERIMENTAL;

EID: 0032472352     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(97)00115-6     Document Type: Article

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