Pluronic P85 increases permeability of a broad spectrum of drugs in polarized BBMEC and Caco-2 cell monolayers

Pharmaceutical Research

Volumn 16, Issue 9, 1999, Pages 1366-1372

  Batrakova, Elena V ^a   Li, Shu ^a   Miller, Donald W ^a   Kabanov, Alexander V ^a  

^a NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Blood brain barrier; Intestinal barrier; MRP; P gp; Pluronic block copolymer

Indexed keywords

COPOLYMER; DOXORUBICIN; ETOPOSIDE; FLUORESCEIN; GLYCOPROTEIN P; LOPERAMIDE; MANNITOL; MULTIDRUG RESISTANCE PROTEIN; PACLITAXEL; POLOXAMER; RHODAMINE 123; VALPROIC ACID; ZIDOVUDINE;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; CATTLE; CELL STRAIN CACO 2; DRUG PENETRATION; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ANIMALS; ANTIDIARRHEALS; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BLOOD-BRAIN BARRIER; CACO-2 CELLS; CATTLE; CONTRAST MEDIA; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; ETOPOSIDE; EXCIPIENTS; FLUORESCEIN; HUMANS; INTESTINAL ABSORPTION; LOPERAMIDE; MICELLES; MICROCIRCULATION; P-GLYCOPROTEIN; PACLITAXEL; POLOXAMER; TRITIUM; VALPROIC ACID; ZIDOVUDINE;

EID: 0032883658     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018990706838     Document Type: Article

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