Methoxy poly(ethylene glycol) and ε-caprolactone amphiphilic block copolymeric micelle containing indomethacin. II. Micelle formation and drug release behaviours

Journal of Controlled Release

Volumn 51, Issue 1, 1998, Pages 13-22

  Kim, So Yeon ^a   Shin, Il Gyun ^a   Lee, Young Moo ^a   Cho, Chong Su ^b   Sung, Yong Kiel ^c  

^a Hanyang University   (South Korea)

^b Chonnam National University   (South Korea)

^c Dongguk University   (South Korea)

Author keywords

Controlled release system; Indomethacin; Methoxypolyethylene caprolactone block copolymer; Micelle; Nanosphere

Indexed keywords

CAPROLACTONE; COPOLYMER; DRUG CARRIER; INDOMETACIN; MACROGOL; METHOXYPOLYETHYLENE GLYCOL; NANOPARTICLE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; MICELLE; MOLECULAR WEIGHT; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; INDOMETHACIN; MICELLES; MOLECULAR WEIGHT; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032559233     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(97)00124-7     Document Type: Article

References (40)

1. M.A. El-Nokaly, D.M. Piatt, B.A. Charpentier, Polymeric delivery systems, American chemical society, Washington, DC, 1993.
2. Kreuter J. Nanoparticle-based drug delivery systems. J. Control. Release. 16:1991;169-176.
3. Seijo B., Fattal E., Treupel L.R., Couvreur P. Design of nanoparticles of less than 50 nm diameter: preparation, characterization and loading. Int. J. Pharm. 62:1990;1-7.
4. Kossovsky N., Millet D., Gelman A., Sponsler E., Hnatyszyn H.J. Self-assembling nanostructures. Biol. Technolgy. 11:1993;1534-1536.
5. Whitesides G.M., Mathias J.P., Seto C.T. Molecular self-assembly and nanochemistry: a chemical strategy for the synthesis of nanostructures. Science. 254:1991;1312-1319.
6. Allemann E., Gurny R., Doelker E. Drug-laoded nanoparticles preparation methods and drug targeting issues. Eur. J. Pharm. Biopharm. 39:1993;173-191.
7. Peppas L.B. Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug delivery. Int. J. Pharm. 116:1995;1-9.
8. M.J. Alonso, Drug and the pharmaceutical sciences vol. 77: Microparticulate systems for the delivery of proteins and vaccines, Marcel Dekker, Inc., USA, 1996, pp. 203-242.
9. Guterres S.S., Fessi H., Barratt G., Devissaguet J.P., Puisieux F. Poly(DL-lactide) nanocapsules containing diclofenac: I. formulation and stability study. Int. J. Pharm. 113:1995;57-63.
10. Uchida T., Yoshida K., Ninomiya A., Goto S. Optimization of preparative conditions for polylactide (PLA) microspheres containing ovalbumin. Chem. Pharm. Bull. 43:1995;1569-1573.
11. Spenlehauer G., Vert M., Benoit J.P., Chabot F., Veillard M. Biodegradable cisplatin microspheres prepared by the solvent evaporation method: molphology and release characteristics. J. Control. Release. 7:1988;217-229.
12. Miyazaki S., Hashiguchi N., Hou W.M., Yokouchi C., Takada M. Preparation and evaluation in vitro and in vivo of fibrinogen microspheres containing adriamycin. Chem. Pharm. Bull. 34:1986;3384-3393.
13. Ohya Y., Takei T., Fukushima H., Ouchi T. Preparation of albumin microspheres grafted galactose residues through polyethylene-glycol spacers, release behavior of 5-fluorouracil from them, and their lectin-mediated aggregation. J. Macromol. Sci. 8:1991;743-760.
14. Verdun C., Couvreur P., Vranckx H., Lenaerts V., Roland M. Development of a nanoparticle controlled-release formation for human use. J. Control. Release. 3:1986;205-210.
15. Cavallaro G., Fresta M., Giammona G., Puglisi G., Villari A. Entrapment of β- lactams antibiotics in polyethylcyanoacrylate nanoparticles: studies on the possible in vivo application of this colloidal delivery system. Int. J. Pharm. 111:1994;31-41.
16. Jalil R., Nixon J.R. Biodegradable poly(lactic acid) and poly(lactide-co-glycolide) microcapsules: problems associated with preparative techniques and release properties. J. Microencapsulation. 7:1990;297-325.
17. Yokoyama M., Okano T., Sakurai Y., Ekimoto H., Shibazaki C., Kataoka K. Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood. Cancer Research. 51:1991;3229-3236.
18. Kataoka K., Kwon G.S., Yokoyama M., Okano T., Sakurai Y. Block copolymer micelles as vehicles for drug delivery. J. Control. Release. 24:1993;119-132.
19. Cho C.S., Na J.W., Jeong Y.I., Kim S.H., Lee Y.M., Sung Y.K. Micelle formation of the hexablock copolymer consisting of poly(γ-benzyl L-glutamate) as the hydrophobic part and poly(ethylene oxide) as the hydrophilic part. Polymer (Korea). 19:1995;926-931.
20. Gao Z., Varshney S.K., Wong S., Eisenberg A. Block copolymer "crew-cut" micelles in water. Macromolecules. 27:1994;7923-7927.
21. Huatan H., Collett J.H., Attwood D. The microencapsulation of protein using a novel ternary blend based on poly (ε-caprolactone). J. Microencapsulation. 12:1995;557-567.
22. Bazile D., Prud'homme C., Bassoullet M.T., Marlard M., Spenlehauer G., Villard M. Stealth Me.PEG-PLA nanoparticles avoid uptake by the mononuclear phagocytes system. J. Pharm. Sci. 84:1995;493-498.
23. Yokoyama M., Miyauchi M., Yamada N., Okano T., Sakurai Y., Kataoka K., Inoue S. Polymer micelles as novel drug carrier: adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. J. Control. Release. 11:1990;269-278.
24. Kwon G.S., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Biodistribution of micelle-forming polymer-drug conjugates. Pharm. Res. 10:1993;970-973.
25. R. Gref, Y. Minamitake, M.T. Peracchia, R. Langer, Microparticulate systems for the delivery of protein and vaccines, Marcel Dekker, Inc., USA, 1996, pp. 279-306.
26. Astafieva I., Zhong X.F., Eisenberg A. Critical micellization phennmena in block polyelectrolyte solutions. Macromolecules. 26:1993;7339-7352.
27. Gao Z., Eisenberg A. A model of micellization for block copolymers in solutions. Macromolecules. 26:1993;7353-7360.
28. Quintana J.R., Janez M.D., Katime I. Formation of block copolymer micelles in solution of linear homopolymer in a good solvent. Macromol. Rapid Commun. 16:1995;607-612.
29. Quintana J.R., Villacampa M., Munoz M., Andrio A., Katime A. Micellization of a polystyrene-block-poly(ethylene/propylene) copolymer in n-alkanes. 1: Thermodynamic study. Macromolecules. 25:1992;3125-3128.
30. Munk P., Qin A., Tian M., Ramireddy C., Webber S.E., Tuzar Z., Prochazka K. Characterization of block copolymer micelles in aqueous media. J. Appl. Polym. Sci. Appl. Polym. Symposium. 52:1993;45-54.
31. Hamad E., Qutubuddin S. Theory of micelle formation by amphiphilic side-chain polymers. Macromolecules. 23:1990;4185-4191.
32. Malmsten M., Lindman B. Self-assembly in aqueous block copolymer solutions. Macromolecules. 25:1992;5440-5445.
33. Price C., Stubbersfield R.B., Kafrawy S.E., Kendall K.D. Thermodynamics of micellization of polystyrene-block-poly(ethylene/propylene) copolymers in decane. Br. Polym. J. 21:1989;391-394.
34. Jones J.L., Marques C.M., Joanny J.F. Shear-induced micellization of diblock copolymers. Macromolecules. 28:1995;136-142.
35. I.G. Shin, S.Y. Kim, Y.M. Lee, C.S. Cho, Y.K. Sung, Methoxy Poly (ethylene Glycol)/ε-Caprolactone Amphiphilic Block Copolymeric Micelle Containing Indomethacin: I. Preparation and Characterization, J. Control. Release submitted.
36. Cerri P., Tricoli M., Lelli L., Guerra G.D., Guerra R.S., Cascone M.G., Giusti P. Block copolymers of L-lactide and poly(ethylene glycol) for biomedical applications. J. Mater. Sci.: Materials in Medicine. 5:1994;308-313.
37. F. Puisieux, G. Barratt, G. Couarraze, P. Couvreur, J.P. Devissaguet, C. Dubernet, E. Fattal, H. Fessi, C. Vauthier, Polymeric Biomaterials, Marcel Dekker, Inc., pp. 749-794.
38. Niwa T., Takeuchi H., Hino T., Kunou N., Kawashima Y. In vitro release behavior of D,L-lactide/glycolide copolymer (PLGA) nanospheres with nafarelin acetate prepared by a novel spontaneous emulsification solvent diffusion method. J. Pharm. Sci. 36:1988;1095-1103.
39. La S.B., Okano T., Kataoka K. Preparation and characterization of the micelle-forming polymeric drug indomethacin -incorporated poly (ethylene oxide)-poly(β-benzyl L-asparatate) block copolymer micelles. J. Pharm. Sci. 85:1996;85-90.
40. Provencher S.W., Hendrixs J. Direct determination of molecular weight distributions of polystyrene in cyclohexane with photon correlation. J. Chem. Phys. 69:1978;4273-4276.