Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing

Journal of the American Chemical Society

Volumn 126, Issue 42, 2004, Pages 13612-13613

  Itaka, Keiji ^a,b   Kanayama, Naoki ^a   Nishiyama, Nobuhiro ^a   Jang, Woo Dong ^a   Yamasaki, Yuichi ^a   Nakamura, Kozo ^b   Kawaguchi, Hiroshi ^b   Kataoka, Kazunori ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CATION; DIAMINE; DRUG CARRIER; MACROGOL; NANOPARTICLE; SMALL INTERFERING RNA;

ARTICLE; COMPLEX FORMATION; DNA SEQUENCE; DRUG DESIGN; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; INCUBATION TIME; ISOMER; KNOCKOUT GENE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERIZATION; POTASSIUM CELL LEVEL; PROTEIN LOCALIZATION; PROTON TRANSPORT; STOICHIOMETRY;

CATIONS; DIAMINES; DNA; GENE SILENCING; HUMANS; KINETICS; NANOSTRUCTURES; PEPTIDES; POLYETHYLENE GLYCOLS; RNA, SMALL INTERFERING;

EID: 6444243630     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja047174r     Document Type: Article

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