An essential relationship between ATP depletion and chemosensitizing activity of Pluronic® block copolymers

Journal of Controlled Release

Volumn 91, Issue 1-2, 2003, Pages 75-83

  Kabanov, Alexander V ^a   Batrakova, Elena V ^a   Alakhov, Valery Yu ^b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b Supratek Pharma Inc   (Canada)

Author keywords

Anthracycline antibiotics; Block copolymer; Cancer; Multidrug resistant protein; Multiple drug resistance; P glycoprotein; Poloxamer

Indexed keywords

CELLS; CHEMOTHERAPY; COPOLYMERS; DRUG PRODUCTS; TUMORS;

MULTI-DRUG RESISTANCE (MDR);

SENSITIVITY ANALYSIS;

ADENOSINE TRIPHOSPHATE; ANTHRACYCLINE ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; CARRIER PROTEIN; DOXORUBICIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; POLOXAMER; PROTEIN P85; SP 1049 C;

BREAST CANCER; CANCER; CANCER CELL; CANCER RESISTANCE; CLINICAL TRIAL; CONFERENCE PAPER; CORRELATION ANALYSIS; DRUG FORMULATION; DRUG MECHANISM; HUMAN; LUNG CANCER; MULTIDRUG RESISTANCE; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; ANIMAL; DRUG RESISTANCE; ENERGY METABOLISM; GENETICS; METABOLISM; NEOPLASM; PHYSIOLOGY; REVIEW;

ADENOSINE TRIPHOSPHATE; ANIMALS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENERGY METABOLISM; HUMANS; NEOPLASMS; P-GLYCOPROTEIN; POLOXAMER;

EID: 0141955916     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(03)00211-6     Document Type: Conference Paper

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