-
1
-
-
0030831130
-
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
-
Kondo, M., Weissman, I. L., & Akashi, K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91, 661-672 (1997).
-
(1997)
Cell
, vol.91
, pp. 661-672
-
-
Kondo, M.1
Weissman, I.L.2
Akashi, K.3
-
2
-
-
0034624828
-
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
-
Akashi, K., Traver, D., Miyamoto, T., & Weissman, I. L. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404, 193-197 (2000).
-
(2000)
Nature
, vol.404
, pp. 193-197
-
-
Akashi, K.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
-
3
-
-
39349096526
-
Hematopoiesis: An evolving paradigm for stem cell biology
-
Orkin, S. H., & Zon, L. I. Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132, 631-644 (2008).
-
(2008)
Cell
, vol.132
, pp. 631-644
-
-
Orkin, S.H.1
Zon, L.I.2
-
4
-
-
28544436371
-
Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates
-
Passegue, E., Wagers, A. J., Giuriato, S., Anderson, W. C., & Weissman, I. L. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J. Exp. Med. 202, 1599-1611 (2005).
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1599-1611
-
-
Passegue, E.1
Wagers, A.J.2
Giuriato, S.3
Anderson, W.C.4
Weissman, I.L.5
-
5
-
-
78651486442
-
Densely interconnected transcriptional circuits control cell states in human hematopoiesis
-
Novershtern, N. et al. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell 144, 296-309 (2011).
-
(2011)
Cell
, vol.144
, pp. 296-309
-
-
Novershtern, N.1
-
6
-
-
84866129506
-
Less is more: Unveiling the functional core of hematopoietic stem cells through knockout mice
-
Rossi, L. et al. Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. Cell Stem Cell 11, 302-317 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 302-317
-
-
Rossi, L.1
-
7
-
-
84879421185
-
The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment
-
Laurenti, E. et al. The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment. Nat. Immunol. 14, 756-763 (2013).
-
(2013)
Nat. Immunol.
, vol.14
, pp. 756-763
-
-
Laurenti, E.1
-
8
-
-
84922541996
-
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA Methylome analysis
-
Cabezas-Wallscheid, N. et al. Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA Methylome analysis. Cell Stem Cell 15, 507-522 (2014).
-
(2014)
Cell Stem Cell
, vol.15
, pp. 507-522
-
-
Cabezas-Wallscheid, N.1
-
9
-
-
0042383366
-
Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential
-
Martin, C. H. et al. Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential. Nat. Immunol. 4, 866-873 (2003).
-
(2003)
Nat. Immunol.
, vol.4
, pp. 866-873
-
-
Martin, C.H.1
-
10
-
-
33644641356
-
Determinants of lymphoid-myeloid lineage diversification
-
Laiosa, C. V., Stadtfeld, M., & Graf, T. Determinants of lymphoid-myeloid lineage diversification. Annu. Rev. Immunol. 24, 705-738 (2006).
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 705-738
-
-
Laiosa, C.V.1
Stadtfeld, M.2
Graf, T.3
-
11
-
-
0034699390
-
Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines
-
Kondo, M. et al. Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines. Nature 407, 383-386 (2000).
-
(2000)
Nature
, vol.407
, pp. 383-386
-
-
Kondo, M.1
-
12
-
-
20244387299
-
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
-
Adolfsson, J. et al. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 121, 295-306 (2005).
-
(2005)
Cell
, vol.121
, pp. 295-306
-
-
Adolfsson, J.1
-
13
-
-
84883428326
-
Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells
-
Yamamoto, R. et al. Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells. Cell 154, 1112-1126 (2013).
-
(2013)
Cell
, vol.154
, pp. 1112-1126
-
-
Yamamoto, R.1
-
14
-
-
77449093887
-
Hematopoietic stem cell heterogeneity: Subtypes, not unpredictable behavior
-
Schroeder, T. Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior. Cell Stem Cell 6, 203-207 (2010).
-
(2010)
Cell Stem Cell
, vol.6
, pp. 203-207
-
-
Schroeder, T.1
-
15
-
-
34848896359
-
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy
-
Pronk, C. J. et al. Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell 1, 428-442 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 428-442
-
-
Pronk, C.J.1
-
16
-
-
34948831114
-
Defining the pathways of early adult hematopoiesis
-
Murre, C. Defining the pathways of early adult hematopoiesis. Cell Stem Cell 1, 357-358 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 357-358
-
-
Murre, C.1
-
17
-
-
34848883146
-
Reciprocal activation of GATA 1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages
-
Arinobu, Y. et al. Reciprocal activation of GATA 1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages. Cell Stem Cell 1, 416-427 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 416-427
-
-
Arinobu, Y.1
-
18
-
-
84876297531
-
Diverse and heritable lineage imprinting of early haematopoietic progenitors
-
Naik, S. H. et al. Diverse and heritable lineage imprinting of early haematopoietic progenitors. Nature 496, 229-232 (2013).
-
(2013)
Nature
, vol.496
, pp. 229-232
-
-
Naik, S.H.1
-
19
-
-
71849114718
-
Balancing dormant and self-renewing hematopoietic stem cells
-
Wilson, A., Laurenti, E., & Trumpp, A. Balancing dormant and self-renewing hematopoietic stem cells. Curr. Opin. Genet. Dev. 19, 461-468 (2009).
-
(2009)
Curr. Opin. Genet. Dev.
, vol.19
, pp. 461-468
-
-
Wilson, A.1
Laurenti, E.2
Trumpp, A.3
-
20
-
-
56549128268
-
Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
-
Wilson, A. et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 135, 1118-1129 (2008).
-
(2008)
Cell
, vol.135
, pp. 1118-1129
-
-
Wilson, A.1
-
21
-
-
0028534860
-
The long-Term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
-
Morrison, S. J., & Weissman, I. L. The long-Term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1, 661-673 (1994).
-
(1994)
Immunity
, vol.1
, pp. 661-673
-
-
Morrison, S.J.1
Weissman, I.L.2
-
22
-
-
84937023176
-
Functionally distinct subsets of lineage-biased multipotent progenitors control blood production in normal and regenerative conditions
-
Pietras, E. M. et al. Functionally distinct subsets of lineage-biased multipotent progenitors control blood production in normal and regenerative conditions. Cell Stem Cell 17, 35-46 (2015).
-
(2015)
Cell Stem Cell
, vol.17
, pp. 35-46
-
-
Pietras, E.M.1
-
23
-
-
34247092922
-
Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors
-
Mansson, R. et al. Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors. Immunity 26, 407-419 (2007).
-
(2007)
Immunity
, vol.26
, pp. 407-419
-
-
Mansson, R.1
-
24
-
-
36749098400
-
Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood
-
Majeti, R., Park, C. Y., & Weissman, I. L. Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. Cell Stem Cell 1, 635-645 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 635-645
-
-
Majeti, R.1
Park, C.Y.2
Weissman, I.L.3
-
25
-
-
21244463426
-
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
-
Kiel, M. J. et al. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121, 1109-1121 (2005).
-
(2005)
Cell
, vol.121
, pp. 1109-1121
-
-
Kiel, M.J.1
-
26
-
-
80053133049
-
Inflammatory modulation of HSCs: Viewing the HSC as a foundation for the immune response
-
King, K. Y., & Goodell, M. A. Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nature reviews. Immunology 11, 685-692 (2011).
-
(2011)
Nature Reviews. Immunology
, vol.11
, pp. 685-692
-
-
King, K.Y.1
Goodell, M.A.2
-
27
-
-
79751536458
-
Inflammatory signals regulate hematopoietic stem cells
-
Baldridge, M. T., King, K. Y., & Goodell, M. A. Inflammatory signals regulate hematopoietic stem cells. Trends Immunol. 32, 57-65 (2011).
-
(2011)
Trends Immunol.
, vol.32
, pp. 57-65
-
-
Baldridge, M.T.1
King, K.Y.2
Goodell, M.A.3
-
28
-
-
77951926024
-
Cutting edge: Bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling
-
Scumpia, P. O. et al. Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling. J. Immunol. 184, 2247-2251 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 2247-2251
-
-
Scumpia, P.O.1
-
29
-
-
84902436102
-
Infection mobilizes hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signaling
-
Burberry, A. et al. Infection mobilizes hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signaling. Cell Host Microbe 15, 779-791 (2014).
-
(2014)
Cell Host Microbe
, vol.15
, pp. 779-791
-
-
Burberry, A.1
-
30
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
Tothova, Z. et al. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 128, 325-339 (2007).
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
-
31
-
-
79955530513
-
Chronic exposure to a TLR ligand injures hematopoietic stem cells
-
Esplin, B. L. et al. Chronic exposure to a TLR ligand injures hematopoietic stem cells. J. Immunol. 186, 5367-5375 (2011).
-
(2011)
J. Immunol.
, vol.186
, pp. 5367-5375
-
-
Esplin, B.L.1
-
32
-
-
77953462161
-
Quiescent haematopoietic stem cells are activated by IFN-? in response to chronic infection
-
Baldridge, M. T., King, K. Y., Boles, N. C., Weksberg, D. C., & Goodell, M. A. Quiescent haematopoietic stem cells are activated by IFN-? in response to chronic infection. Nature 465, 793-797 (2010).
-
(2010)
Nature
, vol.465
, pp. 793-797
-
-
Baldridge, M.T.1
King, K.Y.2
Boles, N.C.3
Weksberg, D.C.4
Goodell, M.A.5
-
33
-
-
84906254220
-
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
-
Flach, J. et al. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature 512, 198-202 (2014).
-
(2014)
Nature
, vol.512
, pp. 198-202
-
-
Flach, J.1
-
34
-
-
33847304124
-
CD34+ hematopoietic stem-progenitor cell microRNA expression and function: A circuit diagram of differentiation control
-
Georgantas, R. W., 3rd et al. CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control. Proc. Natl Acad. Sci. USA 104, 2750-2755 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 2750-2755
-
-
Georgantas, R.W.1
-
35
-
-
77956270732
-
MicroRNA miR 125a controls hematopoietic stem cell number
-
Guo, S. et al. MicroRNA miR 125a controls hematopoietic stem cell number. Proc. Natl Acad. Sci. USA 107, 14229-14234 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 14229-14234
-
-
Guo, S.1
-
36
-
-
84937597623
-
The microRNA 132 and microRNA 212 cluster regulates hematopoietic stem cell maintenance and survival with age by buffering FOXO3 expression
-
Mehta, A. et al. The microRNA 132 and microRNA 212 cluster regulates hematopoietic stem cell maintenance and survival with age by buffering FOXO3 expression. Immunity 42, 1021-1032 (2015).
-
(2015)
Immunity
, vol.42
, pp. 1021-1032
-
-
Mehta, A.1
-
37
-
-
77956288810
-
MicroRNAs enriched in hematopoietic stem cells differentially regulate long-Term hematopoietic output
-
Oconnell, R. M. et al. MicroRNAs enriched in hematopoietic stem cells differentially regulate long-Term hematopoietic output. Proc. Natl Acad. Sci. USA 107, 14235-14240 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 14235-14240
-
-
Oconnell, R.M.1
-
38
-
-
3242669145
-
Tie2/angiopoietin 1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
-
Arai, F. et al. Tie2/angiopoietin 1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 118, 149-161 (2004).
-
(2004)
Cell
, vol.118
, pp. 149-161
-
-
Arai, F.1
-
39
-
-
84874192375
-
FOXO3A directs a protective autophagy program in haematopoietic stem cells
-
Warr, M. R. et al. FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature 494, 323-327 (2013).
-
(2013)
Nature
, vol.494
, pp. 323-327
-
-
Warr, M.R.1
-
40
-
-
33744978765
-
Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment
-
Nagai, Y. et al. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity 24, 801-812 (2006).
-
(2006)
Immunity
, vol.24
, pp. 801-812
-
-
Nagai, Y.1
-
41
-
-
84898012347
-
Conversion of danger signals into cytokine signals by hematopoietic stem and progenitor cells for regulation of stress-induced hematopoiesis
-
Zhao, J. L. et al. Conversion of danger signals into cytokine signals by hematopoietic stem and progenitor cells for regulation of stress-induced hematopoiesis. Cell Stem Cell 14, 445-459 (2014).
-
(2014)
Cell Stem Cell
, vol.14
, pp. 445-459
-
-
Zhao, J.L.1
-
42
-
-
77955902024
-
The widespread regulation of microRNA biogenesis, function and decay
-
Krol, J., Loedige, I., & Filipowicz, W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11, 597-610 (2010).
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 597-610
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
43
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel, D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004).
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
44
-
-
60949102130
-
Dicer is regulated by cellular stresses and interferons
-
Wiesen, J. L., & Tomasi, T. B. Dicer is regulated by cellular stresses and interferons. Mol. Immunol. 46, 1222-1228 (2009).
-
(2009)
Mol. Immunol.
, vol.46
, pp. 1222-1228
-
-
Wiesen, J.L.1
Tomasi, T.B.2
-
45
-
-
67749143728
-
Modulation of microRNA processing by p53
-
Suzuki, H. I. et al. Modulation of microRNA processing by p53. Nature 460, 529-533 (2009).
-
(2009)
Nature
, vol.460
, pp. 529-533
-
-
Suzuki, H.I.1
-
46
-
-
33845295461
-
Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules
-
Leung, A. K., Calabrese, J. M., & Sharp, P. A. Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc. Natl Acad. Sci. USA 103, 18125-18130 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 18125-18130
-
-
Leung, A.K.1
Calabrese, J.M.2
Sharp, P.A.3
-
47
-
-
84875778506
-
Regulation of miRNA biogenesis and turnover in the immune system
-
Bronevetsky, Y., & Ansel, K. M. Regulation of miRNA biogenesis and turnover in the immune system. Immunol. Rev. 253, 304-316 (2013).
-
(2013)
Immunol. Rev.
, vol.253
, pp. 304-316
-
-
Bronevetsky, Y.1
Ansel, K.M.2
-
48
-
-
84858379476
-
MicroRNAs in stress signaling and human disease
-
Mendell, J. T., & Olson, E. N. MicroRNAs in stress signaling and human disease. Cell 148, 1172-1187 (2012).
-
(2012)
Cell
, vol.148
, pp. 1172-1187
-
-
Mendell, J.T.1
Olson, E.N.2
-
49
-
-
78649378267
-
MicroRNA functions in stress responses
-
Leung, A. K., & Sharp, P. A. MicroRNA functions in stress responses. Mol. Cell 40, 205-215 (2010).
-
(2010)
Mol. Cell
, vol.40
, pp. 205-215
-
-
Leung, A.K.1
Sharp, P.A.2
-
50
-
-
67349273027
-
MicroRNA in autoimmunity and autoimmune diseases
-
Pauley, K. M., Cha, S., & Chan, E. K. MicroRNA in autoimmunity and autoimmune diseases. J. Autoimmun. 32, 189-194 (2009).
-
(2009)
J. Autoimmun.
, vol.32
, pp. 189-194
-
-
Pauley, K.M.1
Cha, S.2
Chan, E.K.3
-
51
-
-
77956339881
-
OncomiR addiction in an in vivo model of microRNA 21 induced pre B cell lymphoma
-
Medina, P. P., Nolde, M., & Slack, F. J. OncomiR addiction in an in vivo model of microRNA 21 induced pre B cell lymphoma. Nature 467, 86-90 (2010).
-
(2010)
Nature
, vol.467
, pp. 86-90
-
-
Medina, P.P.1
Nolde, M.2
Slack, F.J.3
-
52
-
-
33645294070
-
Oncomirs-microRNAs with a role in cancer
-
Esquela-Kerscher, A., & Slack, F. J. Oncomirs-microRNAs with a role in cancer. Nat. Rev. Cancer 6, 259-269 (2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
53
-
-
77953763449
-
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate
-
Lin, Y. C. et al. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat. Immunol. 11, 635-643 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 635-643
-
-
Lin, Y.C.1
-
54
-
-
84871390259
-
Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B cell fate
-
Mansson, R. et al. Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B cell fate. Proc. Natl Acad. Sci. USA 109, 21028-21033 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 21028-21033
-
-
Mansson, R.1
-
55
-
-
84866361701
-
Circuitry and dynamics of human transcription factor regulatory networks
-
Neph, S. et al. Circuitry and dynamics of human transcription factor regulatory networks. Cell 150, 1274-1286 (2012).
-
(2012)
Cell
, vol.150
, pp. 1274-1286
-
-
Neph, S.1
-
56
-
-
84860324470
-
Roles for microRNAs in conferring robustness to biological processes
-
Ebert, M. S., & Sharp, P. A. Roles for microRNAs in conferring robustness to biological processes. Cell 149, 515-524 (2012).
-
(2012)
Cell
, vol.149
, pp. 515-524
-
-
Ebert, M.S.1
Sharp, P.A.2
-
57
-
-
77957664647
-
MicroRNAs as regulators of differentiation and cell fate decisions
-
Ivey, K. N., & Srivastava, D. MicroRNAs as regulators of differentiation and cell fate decisions. Cell Stem Cell 7, 36-41 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 36-41
-
-
Ivey, K.N.1
Srivastava, D.2
-
58
-
-
84937706626
-
A Single miRNA-mRNA interaction affects the immune response in a context-And cell-Type-specific manner
-
Lu, L. F. et al. A Single miRNA-mRNA interaction affects the immune response in a context-And cell-Type-specific manner. Immunity 43, 52-64 (2015).
-
(2015)
Immunity
, vol.43
, pp. 52-64
-
-
Lu, L.F.1
-
59
-
-
84900873500
-
MicroRNA-based single-gene circuits buffer protein synthesis rates against perturbations
-
Strovas, T. J., Rosenberg, A. B., Kuypers, B. E., Muscat, R. A., & Seelig, G. MicroRNA-based single-gene circuits buffer protein synthesis rates against perturbations. ACS Synthet. Biol. 3, 324-331 (2014).
-
(2014)
ACS Synthet. Biol.
, vol.3
, pp. 324-331
-
-
Strovas, T.J.1
Rosenberg, A.B.2
Kuypers, B.E.3
Muscat, R.A.4
Seelig, G.5
-
61
-
-
84924420342
-
MicroRNAs regulate cell to cell variability of endogenous target gene expression in developing mouse thymocytes
-
Blevins, R. et al. microRNAs regulate cell to cell variability of endogenous target gene expression in developing mouse thymocytes. PLoS Genet. 11, e1005020 (2015).
-
(2015)
PLoS Genet.
, vol.11
, pp. e1005020
-
-
Blevins, R.1
-
62
-
-
84887120736
-
Dampening of expression oscillations by synchronous regulation of a microRNA and its target
-
Kim, D., Grun, D., & van Oudenaarden, A. Dampening of expression oscillations by synchronous regulation of a microRNA and its target. Nat. Genet. 45, 1337-1344 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 1337-1344
-
-
Kim, D.1
Grun, D.2
Van Oudenaarden, A.3
-
63
-
-
80052266532
-
MicroRNAs can generate thresholds in target gene expression
-
Mukherji, S. et al. MicroRNAs can generate thresholds in target gene expression. Nat. Genet. 43, 854-859 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 854-859
-
-
Mukherji, S.1
-
64
-
-
84907678240
-
Understanding cooperativity of microRNAs via microRNA association networks
-
Na, Y. J., & Kim, J. H. Understanding cooperativity of microRNAs via microRNA association networks. BMC genomics 14 (Suppl. 5), S17 (2013).
-
(2013)
BMC Genomics 14 (Suppl. 5)
, vol.17
-
-
Na, Y.J.1
Kim, J.H.2
-
65
-
-
34249079154
-
Network motifs: Theory and experimental approaches
-
Alon, U. Network motifs: theory and experimental approaches. Nat. Rev. Genet. 8, 450-461 (2007).
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 450-461
-
-
Alon, U.1
-
66
-
-
77954517267
-
MicroRNAs and gene regulatory networks: Managing the impact of noise in biological systems
-
Herranz, H., & Cohen, S. M. MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems. Genes Dev. 24, 1339-1344 (2010).
-
(2010)
Genes Dev.
, vol.24
, pp. 1339-1344
-
-
Herranz, H.1
Cohen, S.M.2
-
67
-
-
84892610064
-
The bone marrow niche for haematopoietic stem cells
-
Morrison, S. J., & Scadden, D. T. The bone marrow niche for haematopoietic stem cells. Nature 505, 327-334 (2014).
-
(2014)
Nature
, vol.505
, pp. 327-334
-
-
Morrison, S.J.1
Scadden, D.T.2
-
68
-
-
84943154962
-
Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal
-
Acar, M. et al. Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal. Nature 526, 126-130 (2015).
-
(2015)
Nature
, vol.526
, pp. 126-130
-
-
Acar, M.1
-
69
-
-
43949134440
-
MicroRNAs play a role in the development of human hematopoietic stem cells
-
Liao, R. et al. MicroRNAs play a role in the development of human hematopoietic stem cells. J. Cell. Biochem. 104, 805-817 (2008).
-
(2008)
J. Cell. Biochem.
, vol.104
, pp. 805-817
-
-
Liao, R.1
-
70
-
-
79955425509
-
Combined characterization of microRNA and mRNA profiles delineates early differentiation pathways of CD133+ and CD34+ hematopoietic stem and progenitor cells
-
Bissels, U. et al. Combined characterization of microRNA and mRNA profiles delineates early differentiation pathways of CD133+ and CD34+ hematopoietic stem and progenitor cells. Stem Cells 29, 847-857 (2011).
-
(2011)
Stem Cells
, vol.29
, pp. 847-857
-
-
Bissels, U.1
-
71
-
-
67650590937
-
Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation
-
Gruber, J. J. et al. Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell 138, 328-339 (2009).
-
(2009)
Cell
, vol.138
, pp. 328-339
-
-
Gruber, J.J.1
-
72
-
-
84855824354
-
Genetic screen identifies microRNA cluster 99b/let 7e/125a as a regulator of primitive hematopoietic cells
-
Gerrits, A. et al. Genetic screen identifies microRNA cluster 99b/let 7e/125a as a regulator of primitive hematopoietic cells. Blood 119, 377-387 (2012).
-
(2012)
Blood
, vol.119
, pp. 377-387
-
-
Gerrits, A.1
-
73
-
-
84858257170
-
Oncomir miR 125b regulates hematopoiesis by targeting the gene Lin28A
-
Chaudhuri, A. A. et al. Oncomir miR 125b regulates hematopoiesis by targeting the gene Lin28A. Proc. Natl Acad. Sci. USA 109, 4233-4238 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 4233-4238
-
-
Chaudhuri, A.A.1
-
74
-
-
84961218873
-
The microRNA 212/132 cluster regulates B cell development by targeting Sox4
-
Mehta, A. et al. The microRNA 212/132 cluster regulates B cell development by targeting Sox4. J. Exp. Med. 212, 1679-1692 (2015).
-
(2015)
J. Exp. Med.
, vol.212
, pp. 1679-1692
-
-
Mehta, A.1
-
75
-
-
84880703930
-
Regulation of miR 17 92a cluster processing by the microRNA binding protein SND1
-
Heinrich, E. M. et al. Regulation of miR 17 92a cluster processing by the microRNA binding protein SND1. FEBS Lett. 587, 2405-2411 (2013).
-
(2013)
FEBS Lett.
, vol.587
, pp. 2405-2411
-
-
Heinrich, E.M.1
-
76
-
-
78650722292
-
MicroRNA 125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets
-
Ooi, A. G. et al. MicroRNA 125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets. Proc. Natl Acad. Sci. USA 107, 21505-21510 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 21505-21510
-
-
Ooi, A.G.1
-
77
-
-
84907330294
-
Dual mechanisms by which miR 125b represses IRF4 to induce myeloid and B cell leukemias
-
So, A. Y. et al. Dual mechanisms by which miR 125b represses IRF4 to induce myeloid and B cell leukemias. Blood 124, 1502-1512 (2014).
-
(2014)
Blood
, vol.124
, pp. 1502-1512
-
-
So, A.Y.1
-
78
-
-
84898887673
-
MiR 99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling
-
Emmrich, S. et al. miR 99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling. Genes Dev. 28, 858-874 (2014).
-
(2014)
Genes Dev.
, vol.28
, pp. 858-874
-
-
Emmrich, S.1
-
79
-
-
77449145533
-
Distinct hematopoietic stem cell subtypes are differentially regulated by TGF β1
-
Challen, G. A., Boles, N. C., Chambers, S. M., & Goodell, M. A. Distinct hematopoietic stem cell subtypes are differentially regulated by TGF β1. Cell Stem Cell 6, 265-278 (2010).
-
(2010)
Cell Stem Cell
, vol.6
, pp. 265-278
-
-
Challen, G.A.1
Boles, N.C.2
Chambers, S.M.3
Goodell, M.A.4
-
80
-
-
80053907201
-
Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion
-
Luis, T. C. et al. Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion. Cell Stem Cell 9, 345-356 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 345-356
-
-
Luis, T.C.1
-
81
-
-
77949518018
-
MicroRNA 29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia
-
Han, Y. C. et al. microRNA 29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. J. Exp. Med. 207, 475-489 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 475-489
-
-
Han, Y.C.1
-
82
-
-
84926674795
-
MiR 29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a
-
Hu, W. et al. miR 29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood 125, 2206-2216 (2015).
-
(2015)
Blood
, vol.125
, pp. 2206-2216
-
-
Hu, W.1
-
83
-
-
84880571480
-
The oncogenic microRNA miR 22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation
-
Song, S. J. et al. The oncogenic microRNA miR 22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation. Cell Stem Cell 13, 87-101 (2013).
-
(2013)
Cell Stem Cell
, vol.13
, pp. 87-101
-
-
Song, S.J.1
-
84
-
-
77953087435
-
Methylation and silencing of miRNA 124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome
-
Dickstein, J. et al. Methylation and silencing of miRNA 124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome. Proc. Natl Acad. Sci. USA 107, 9783-9788 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 9783-9788
-
-
Dickstein, J.1
-
85
-
-
78449270317
-
Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy
-
58ra84
-
Gentner, B. et al. Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy. Sci. Transl Med. 2, 58ra84 (2010).
-
(2010)
Sci. Transl Med.
, vol.2
-
-
Gentner, B.1
-
86
-
-
84870894496
-
Attenuation of miR 126 activity expands HSC in vivo without exhaustion
-
Lechman, E. R. et al. Attenuation of miR 126 activity expands HSC in vivo without exhaustion. Cell Stem Cell 11, 799-811 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 799-811
-
-
Lechman, E.R.1
-
87
-
-
84958635003
-
MiR 126 regulates distinct self-renewal outcomes in normal and malignant hematopoietic stem cells
-
Lechman, E. R. et al. miR 126 regulates distinct self-renewal outcomes in normal and malignant hematopoietic stem cells. Cancer Cell 29, 214-228 (2016).
-
(2016)
Cancer Cell
, vol.29
, pp. 214-228
-
-
Lechman, E.R.1
-
88
-
-
47049085267
-
MicroRNA 126 regulates HOXA9 by binding to the homeobox
-
Shen, W. F., Hu, Y. L., Uttarwar, L., Passegue, E., & Largman, C. MicroRNA 126 regulates HOXA9 by binding to the homeobox. Mol. Cell. Biol. 28, 4609-4619 (2008).
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4609-4619
-
-
Shen, W.F.1
Hu, Y.L.2
Uttarwar, L.3
Passegue, E.4
Largman, C.5
-
89
-
-
84881460310
-
The Lin28b let 7 Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells
-
Copley, M. R. et al. The Lin28b let 7 Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells. Nature Cell Biol. 15, 916-925 (2013).
-
(2013)
Nature Cell Biol.
, vol.15
, pp. 916-925
-
-
Copley, M.R.1
-
90
-
-
84862776981
-
Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis
-
Yuan, J., Nguyen, C. K., Liu, X., Kanellopoulou, C., & Muljo, S. A. Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis. Science 335, 1195-1200 (2012).
-
(2012)
Science
, vol.335
, pp. 1195-1200
-
-
Yuan, J.1
Nguyen, C.K.2
Liu, X.3
Kanellopoulou, C.4
Muljo, S.A.5
-
92
-
-
79952186298
-
MicroRNAs: The fine-Tuners of toll-like receptor signalling
-
Oneill, L. A., Sheedy, F. J., & McCoy, C. E. MicroRNAs: the fine-Tuners of Toll-like receptor signalling. Nat. Rev. Immunol. 11, 163-175 (2011).
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 163-175
-
-
Oneill, L.A.1
Sheedy, F.J.2
McCoy, C.E.3
-
93
-
-
33747608638
-
NF κb-dependent induction of microRNA miR 146, an inhibitor targeted to signaling proteins of innate immune responses
-
Taganov, K. D., Boldin, M. P., Chang, K. J., & Baltimore, D. NF κB-dependent induction of microRNA miR 146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl Acad. Sci. USA 103, 12481-12486 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 12481-12486
-
-
Taganov, K.D.1
Boldin, M.P.2
Chang, K.J.3
Baltimore, D.4
-
94
-
-
79959362128
-
NF κb dysregulation in microRNA 146a deficient mice drives the development of myeloid malignancies
-
Zhao, J. L. et al. NF κB dysregulation in microRNA 146a deficient mice drives the development of myeloid malignancies. Proc. Natl Acad. Sci. USA 108, 9184-9189 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 9184-9189
-
-
Zhao, J.L.1
-
95
-
-
84879060116
-
MicroRNA 146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice
-
Zhao, J. L., Rao, D. S., Oconnell, R. M., Garcia-Flores, Y., & Baltimore, D. MicroRNA 146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice. eLife 2, e00537 (2013).
-
(2013)
ELife
, vol.2
, pp. e00537
-
-
Zhao, J.L.1
Rao, D.S.2
Oconnell, R.M.3
Garcia-Flores, Y.4
Baltimore, D.5
-
96
-
-
77955736174
-
MiR 33 mediated downregulation of p53 controls hematopoietic stem cell self-renewal
-
Herrera-Merchan, A. et al. miR 33 mediated downregulation of p53 controls hematopoietic stem cell self-renewal. Cell Cycle) 9, 3277-3285 (2010).
-
(2010)
Cell Cycle)
, vol.9
, pp. 3277-3285
-
-
Herrera-Merchan, A.1
-
97
-
-
84948700160
-
STAT5 regulated microRNA 193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling
-
Haetscher, N. et al. STAT5 regulated microRNA 193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling. Nature Commun. 6, 8928 (2015).
-
(2015)
Nature Commun.
, vol.6
, pp. 8928
-
-
Haetscher, N.1
-
98
-
-
29144440077
-
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation
-
Felli, N. et al. MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc. Natl Acad. Sci. USA 102, 18081-18086 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 18081-18086
-
-
Felli, N.1
-
99
-
-
84859382730
-
MicroRNA regulation of inflammatory responses
-
Oconnell, R. M., Rao, D. S., & Baltimore, D. microRNA regulation of inflammatory responses. Annu. Rev. Immunol. 30, 295-312 (2012).
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 295-312
-
-
Oconnell, R.M.1
Rao, D.S.2
Baltimore, D.3
-
100
-
-
80052936529
-
MicroRNA function in myeloid biology
-
Oconnell, R. M., Zhao, J. L., & Rao, D. S. MicroRNA function in myeloid biology. Blood 118, 2960-2969 (2011).
-
(2011)
Blood
, vol.118
, pp. 2960-2969
-
-
Oconnell, R.M.1
Zhao, J.L.2
Rao, D.S.3
-
101
-
-
84931275600
-
Circadian control of innate immunity in macrophages by mir 155 targeting bmal1
-
Curtis, A. M.et al. Circadian control of innate immunity in macrophages by miR 155 targeting Bmal1. Proc. Natl Acad. Sci. USA 112, 7231-7236 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 7231-7236
-
-
Curtis, A.M.1
-
102
-
-
66349137358
-
Inositol phosphatase SHIP1 is a primary target of miR 155
-
Oconnell, R. M., Chaudhuri, A. A., Rao, D. S., & Baltimore, D. Inositol phosphatase SHIP1 is a primary target of miR 155. Proc. Natl Acad. Sci. USA 106, 7113-7118 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 7113-7118
-
-
Oconnell, R.M.1
Chaudhuri, A.A.2
Rao, D.S.3
Baltimore, D.4
-
103
-
-
33846845071
-
MicroRNA 155 is induced during the macrophage inflammatory response
-
Oconnell, R. M., Taganov, K. D., Boldin, M. P., Cheng, G., & Baltimore, D. MicroRNA 155 is induced during the macrophage inflammatory response. Proc. Natl Acad. Sci. USA 104, 1604-1609 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 1604-1609
-
-
Oconnell, R.M.1
Taganov, K.D.2
Boldin, M.P.3
Cheng, G.4
Baltimore, D.5
-
104
-
-
84903993535
-
Notch-dependent repression of miR 155 in the bone marrow niche regulates hematopoiesis in an NF κb-dependent manner
-
Wang, L. et al. Notch-dependent repression of miR 155 in the bone marrow niche regulates hematopoiesis in an NF κB-dependent manner. Cell Stem Cell 15, 51-65 (2014).
-
(2014)
Cell Stem Cell
, vol.15
, pp. 51-65
-
-
Wang, L.1
-
105
-
-
80054739828
-
MicroRNAs regulate dendritic cell differentiation and function
-
Turner, M. L., Schnorfeil, F. M., & Brocker, T. MicroRNAs regulate dendritic cell differentiation and function. J. Immunol. 187, 3911-3917 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 3911-3917
-
-
Turner, M.L.1
Schnorfeil, F.M.2
Brocker, T.3
-
106
-
-
77957664009
-
MiRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate
-
Mann, M. Barad, O., Agami, R., Geiger, B., & Hornstein, E. miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate. Proc. Natl Acad. Sci. USA 107, 15804-15809 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15804-15809
-
-
Mann Barad M, O.1
Agami, R.2
Geiger, B.3
Hornstein, E.4
-
107
-
-
68649091506
-
The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs
-
Androulidaki, A. et al. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity 31, 220-231 (2009).
-
(2009)
Immunity
, vol.31
, pp. 220-231
-
-
Androulidaki, A.1
-
108
-
-
77954223697
-
IL 10 inhibits miR 155 induction by toll-like receptors
-
McCoy, C. E. et al. IL 10 inhibits miR 155 induction by toll-like receptors. J. Biol. Chem. 285, 20492-20498 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 20492-20498
-
-
McCoy, C.E.1
-
109
-
-
41149130219
-
Sustained expression of microRNA 155 in hematopoietic stem cells causes a myeloproliferative disorder
-
Oconnell, R. M. et al. Sustained expression of microRNA 155 in hematopoietic stem cells causes a myeloproliferative disorder. J. Exp. Med. 205, 585-594 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 585-594
-
-
Oconnell, R.M.1
-
110
-
-
28344438648
-
A minicircuitry comprised of microRNA 223 and transcription factors NFI A and C/EBPα regulates human granulopoiesis
-
Fazi, F. et al. A minicircuitry comprised of microRNA 223 and transcription factors NFI A and C/EBPα regulates human granulopoiesis. Cell 123, 819-831 (2005).
-
(2005)
Cell
, vol.123
, pp. 819-831
-
-
Fazi, F.1
-
111
-
-
77950354353
-
Cell-cycle regulator E2F1 and microRNA 223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia
-
Pulikkan, J. A. et al. Cell-cycle regulator E2F1 and microRNA 223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia. Blood 115, 1768-1778 (2010).
-
(2010)
Blood
, vol.115
, pp. 1768-1778
-
-
Pulikkan, J.A.1
-
112
-
-
39849096995
-
Regulation of progenitor cell proliferation and granulocyte function by microRNA 223
-
Johnnidis, J. B. et al. Regulation of progenitor cell proliferation and granulocyte function by microRNA 223. Nature 451, 1125-1129 (2008).
-
(2008)
Nature
, vol.451
, pp. 1125-1129
-
-
Johnnidis, J.B.1
-
113
-
-
34247483919
-
An evolutionarily conserved mechanism for microRNA 223 expression revealed by microRNA gene profiling
-
Fukao, T. et al. An evolutionarily conserved mechanism for microRNA 223 expression revealed by microRNA gene profiling. Cell 129, 617-631 (2007).
-
(2007)
Cell
, vol.129
, pp. 617-631
-
-
Fukao, T.1
-
114
-
-
84892442548
-
Transcriptional fine-Tuning of microRNA 223 levels directs lineage choice of human hematopoietic progenitors
-
Vian, L. et al. Transcriptional fine-Tuning of microRNA 223 levels directs lineage choice of human hematopoietic progenitors. Cell Death Differ. 21, 290-301 (2014).
-
(2014)
Cell Death Differ.
, vol.21
, pp. 290-301
-
-
Vian, L.1
-
115
-
-
0037244284
-
Intrinsic requirement for zinc finger transcription factor Gfi 1 in neutrophil differentiation
-
Hock, H. et al. Intrinsic requirement for zinc finger transcription factor Gfi 1 in neutrophil differentiation. Immunity 18, 109-120 (2003).
-
(2003)
Immunity
, vol.18
, pp. 109-120
-
-
Hock, H.1
-
116
-
-
66549105485
-
Gfi1 regulates miR 21 and miR 196b to control myelopoiesis
-
Velu, C. S., Baktula, A. M., & Grimes, H. L. Gfi1 regulates miR 21 and miR 196b to control myelopoiesis. Blood 113, 4720-4728 (2009).
-
(2009)
Blood
, vol.113
, pp. 4720-4728
-
-
Velu, C.S.1
Baktula, A.M.2
Grimes, H.L.3
-
117
-
-
84055218897
-
MicroRNA 130a mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF β1 stimulation in granulocytic precursors
-
Hager, M. et al. MicroRNA 130a mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF β1 stimulation in granulocytic precursors. Blood 118, 6649-6659 (2011).
-
(2011)
Blood
, vol.118
, pp. 6649-6659
-
-
Hager, M.1
-
118
-
-
84928588556
-
Let 7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function
-
Pobezinsky, L. A. et al. Let 7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function. Blood 16, 517-524 (2015).
-
(2015)
Blood
, vol.16
, pp. 517-524
-
-
Pobezinsky, L.A.1
-
119
-
-
83755173483
-
Cutting edge: MicroRNA 181 promotes human NK cell development by regulating Notch signaling
-
Cichocki, F. et al. Cutting edge: microRNA 181 promotes human NK cell development by regulating Notch signaling. J. Immunol. 187, 6171-6175 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 6171-6175
-
-
Cichocki, F.1
-
120
-
-
84855501133
-
L miR 150 regulates the development of NK and iNKT cells
-
Bezman, N. A., Chakraborty, T., Bender, T., & Lanier, L. L. miR 150 regulates the development of NK and iNKT cells. J. Exp. Med. 208, 2717-2731 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2717-2731
-
-
Bezman, N.A.1
Chakraborty, T.2
Bender, T.3
Lanier, L.4
-
121
-
-
84875792300
-
MicroRNA function in NK cell biology
-
Beaulieu, A. M. et al. MicroRNA function in NK cell biology. Immunol. Rev. 253, 40-52 (2013).
-
(2013)
Immunol. Rev.
, vol.253
, pp. 40-52
-
-
Beaulieu, A.M.1
-
122
-
-
84868582519
-
Systematic analysis of microRNA fingerprints in thrombocythemic platelets using integrated platforms
-
Xu, X. et al. Systematic analysis of microRNA fingerprints in thrombocythemic platelets using integrated platforms. Blood 120, 3575-3585 (2012).
-
(2012)
Blood
, vol.120
, pp. 3575-3585
-
-
Xu, X.1
-
123
-
-
44449108570
-
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors
-
Lu, J. et al. MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors. Dev. Cell 14, 843-853 (2008).
-
(2008)
Dev. Cell
, vol.14
, pp. 843-853
-
-
Lu, J.1
-
124
-
-
33645525964
-
MicroRNA fingerprints during human megakaryocytopoiesis
-
Garzon, R. et al. MicroRNA fingerprints during human megakaryocytopoiesis. Proc. Natl Acad. Sci. USA 103, 5078-5083 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 5078-5083
-
-
Garzon, R.1
-
125
-
-
77954408884
-
The miR 144/451 locus is required for erythroid homeostasis
-
Rasmussen, K. D. et al. The miR 144/451 locus is required for erythroid homeostasis. J. Exp. Med. 207, 1351-1358 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1351-1358
-
-
Rasmussen, K.D.1
-
126
-
-
84873564061
-
MiR 223 deficiency increases eosinophil progenitor proliferation
-
Lu, T. X. et al. MiR 223 deficiency increases eosinophil progenitor proliferation. J. Immunol. 190, 1576-1582 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 1576-1582
-
-
Lu, T.X.1
-
127
-
-
59849122726
-
MicroRNA 221 222 regulate the cell cycle in mast cells
-
Mayoral, R. J. et al. MicroRNA 221 222 regulate the cell cycle in mast cells. J. Immunol. 182, 433-445 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 433-445
-
-
Mayoral, R.J.1
-
128
-
-
84921334044
-
MicroRNAs in B cells: From normal differentiation to treatment of malignancies
-
Marques, S. C. et al. MicroRNAs in B cells: from normal differentiation to treatment of malignancies. Oncotarget 6, 7-25 (2015).
-
(2015)
Oncotarget
, vol.6
, pp. 7-25
-
-
Marques, S.C.1
-
129
-
-
84884175591
-
MicroRNA regulation of T lymphocyte immunity: Modulation of molecular networks responsible for T cell activation, differentiation, and development
-
Podshivalova, K., & Salomon, D. R. MicroRNA regulation of T lymphocyte immunity: modulation of molecular networks responsible for T cell activation, differentiation, and development. Crit. Rev. Immunol. 33, 435-476 (2013).
-
(2013)
Crit. Rev. Immunol.
, vol.33
, pp. 435-476
-
-
Podshivalova, K.1
Salomon, D.R.2
-
130
-
-
84875769973
-
MicroRNA regulation of T cell development
-
Dooley, J., Linterman, M. A., & Liston, A. MicroRNA regulation of T cell development. Immunol. Rev. 253, 53-64 (2013).
-
(2013)
Immunol. Rev.
, vol.253
, pp. 53-64
-
-
Dooley, J.1
Linterman, M.A.2
Liston, A.3
-
131
-
-
84875760707
-
Regulation of B cell development and function by microRNAs
-
de Yebenes, V. G., Bartolome-Izquierdo, N., & Ramiro, A. R. Regulation of B cell development and function by microRNAs. Immunol. Rev. 253, 25-39 (2013).
-
(2013)
Immunol. Rev.
, vol.253
, pp. 25-39
-
-
De Yebenes, V.G.1
Bartolome-Izquierdo, N.2
Ramiro, A.R.3
-
132
-
-
84874605454
-
The role of microRNAs in B cell development and function
-
Li, J., Wan, Y., Ji, Q., Fang, Y., & Wu, Y. The role of microRNAs in B cell development and function. Cell. Mol. Immunol. 10, 107-112 (2013).
-
(2013)
Cell. Mol. Immunol.
, vol.10
, pp. 107-112
-
-
Li, J.1
Wan, Y.2
Ji, Q.3
Fang, Y.4
Wu, Y.5
-
133
-
-
84875777840
-
MicroRNA regulation of T cell differentiation and function
-
Jeker, L. T., & Bluestone, J. A. MicroRNA regulation of T cell differentiation and function. Immunol. Rev. 253, 65-81 (2013).
-
(2013)
Immunol. Rev.
, vol.253
, pp. 65-81
-
-
Jeker, L.T.1
Bluestone, J.A.2
-
134
-
-
84883162180
-
MicroRNA-mediated regulation of T helper cell differentiation and plasticity
-
Baumjohann, D., & Ansel, K. M. MicroRNA-mediated regulation of T helper cell differentiation and plasticity. Nat. Rev. Immunology 13, 666-678 (2013).
-
(2013)
Nat. Rev. Immunology
, vol.13
, pp. 666-678
-
-
Baumjohann, D.1
Ansel, K.M.2
-
135
-
-
34250212629
-
The transcriptional regulation of B cell lineage commitment
-
Nutt, S. L., & Kee, B. L. The transcriptional regulation of B cell lineage commitment. Immunity 26, 715-725 (2007).
-
(2007)
Immunity
, vol.26
, pp. 715-725
-
-
Nutt, S.L.1
Kee, B.L.2
-
136
-
-
20644461729
-
Transcriptional networks in developing and mature B cells
-
Matthias, P., & Rolink, A. G. Transcriptional networks in developing and mature B cells. Nat. Rev. Immunol. 5, 497-508 (2005).
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 497-508
-
-
Matthias, P.1
Rolink, A.G.2
-
137
-
-
0036669273
-
Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow
-
Igarashi, H., Gregory, S. C., Yokota, T., Sakaguchi, N., & Kincade, P. W. Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity 17, 117-130 (2002).
-
(2002)
Immunity
, vol.17
, pp. 117-130
-
-
Igarashi, H.1
Gregory, S.C.2
Yokota, T.3
Sakaguchi, N.4
Kincade, P.W.5
-
138
-
-
0033166301
-
Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A
-
O?Riordan, M., & Grosschedl, R. Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A. Immunity 11, 21-31 (1999).
-
(1999)
Immunity
, vol.11
, pp. 21-31
-
-
Oriordan, M.1
Grosschedl, R.2
-
139
-
-
34247188078
-
Pax5: The guardian of B cell identity and function
-
Cobaleda, C., Schebesta, A., Delogu, A., & Busslinger, M. Pax5: the guardian of B cell identity and function. Nat. Immunol. 8, 463-470 (2007).
-
(2007)
Nat. Immunol.
, vol.8
, pp. 463-470
-
-
Cobaleda, C.1
Schebesta, A.2
Delogu, A.3
Busslinger, M.4
-
140
-
-
0036906546
-
Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1
-
Souabni, A., Cobaleda, C., Schebesta, M., & Busslinger, M. Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1. Immunity 17, 781-793 (2002).
-
(2002)
Immunity
, vol.17
, pp. 781-793
-
-
Souabni, A.1
Cobaleda, C.2
Schebesta, M.3
Busslinger, M.4
-
141
-
-
84874283550
-
Sox4 is required for the survival of pro B cells
-
Sun, B. et al. Sox4 is required for the survival of pro B cells. J. Immunol. 190, 2080-2089 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 2080-2089
-
-
Sun, B.1
-
142
-
-
84903639223
-
Integrated genetic approaches identify the molecular mechanisms of Sox4 in early B cell development: Intricate roles for RAG1/2 and CK1?
-
Mallampati, S. et al. Integrated genetic approaches identify the molecular mechanisms of Sox4 in early B cell development: intricate roles for RAG1/2 and CK1?. Blood 123, 4064-4076 (2014).
-
(2014)
Blood
, vol.123
, pp. 4064-4076
-
-
Mallampati, S.1
-
143
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen, C. Z., Li, L., Lodish, H. F., & Bartel, D. P. MicroRNAs modulate hematopoietic lineage differentiation. Science 303, 83-86 (2004).
-
(2004)
Science
, vol.303
, pp. 83-86
-
-
Chen, C.Z.1
Li, L.2
Lodish, H.F.3
Bartel, D.P.4
-
144
-
-
65549101556
-
Identification of the human mature B cell miRNome
-
Basso, K. et al. Identification of the human mature B cell miRNome. Immunity 30, 744-752 (2009).
-
(2009)
Immunity
, vol.30
, pp. 744-752
-
-
Basso, K.1
-
145
-
-
66549119328
-
MiRNA profiling of B cell subsets: Specific miRNA profile for germinal center B cells with variation between centroblasts and centrocytes
-
Tan, L. P. et al. miRNA profiling of B cell subsets: specific miRNA profile for germinal center B cells with variation between centroblasts and centrocytes. Lab. Invest. 89, 708-716 (2009).
-
(2009)
Lab. Invest.
, vol.89
, pp. 708-716
-
-
Tan, L.P.1
-
146
-
-
66549101276
-
Patterns of microRNA expression characterize stages of human B cell differentiation
-
Zhang, J. et al. Patterns of microRNA expression characterize stages of human B cell differentiation. Blood 113, 4586-4594 (2009).
-
(2009)
Blood
, vol.113
, pp. 4586-4594
-
-
Zhang, J.1
-
147
-
-
39749101294
-
Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage
-
Koralov, S. B. et al. Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell 132, 860-874 (2008).
-
(2008)
Cell
, vol.132
, pp. 860-874
-
-
Koralov, S.B.1
-
148
-
-
34249851499
-
F miR 150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely
-
Zhou, B., Wang, S., Mayr, C., Bartel, D. P., & Lodish, H. F. miR 150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely. Proc. Natl Acad. Sci. USA 104, 7080-7085 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 7080-7085
-
-
Zhou, B.1
Wang, S.2
Mayr, C.3
Bartel, D.P.4
Lodish, H.5
-
149
-
-
34547941361
-
MiR 150 controls B cell differentiation by targeting the transcription factor c Myb
-
Xiao, C. et al. MiR 150 controls B cell differentiation by targeting the transcription factor c Myb. Cell 131, 146-159 (2007).
-
(2007)
Cell
, vol.131
, pp. 146-159
-
-
Xiao, C.1
-
150
-
-
0022618283
-
Expression of the c myb proto-oncogene during cellular proliferation
-
Thompson, C. B., Challoner, P. B., Neiman, P. E., & Groudine, M. Expression of the c myb proto-oncogene during cellular proliferation. Nature 319, 374-380 (1986).
-
(1986)
Nature
, vol.319
, pp. 374-380
-
-
Thompson, C.B.1
Challoner, P.B.2
Neiman, P.E.3
Groudine, M.4
-
151
-
-
34247641748
-
Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia
-
Lahortiga, I. et al. Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia. Nat. Genet. 39, 593-595 (2007).
-
(2007)
Nat. Genet.
, vol.39
, pp. 593-595
-
-
Lahortiga, I.1
-
152
-
-
77954958215
-
MicroRNA 34a perturbs B lymphocyte development by repressing the forkhead box transcription factor Foxp1
-
Rao, D. S. et al. MicroRNA 34a perturbs B lymphocyte development by repressing the forkhead box transcription factor Foxp1. Immunity 33, 48-59 (2010).
-
(2010)
Immunity
, vol.33
, pp. 48-59
-
-
Rao, D.S.1
-
153
-
-
39749143354
-
Targeted deletion reveals essential and overlapping functions of the miR 17 through 92 family of miRNA clusters
-
Ventura, A. et al. Targeted deletion reveals essential and overlapping functions of the miR 17 through 92 family of miRNA clusters. Cell 132, 875-886 (2008).
-
(2008)
Cell
, vol.132
, pp. 875-886
-
-
Ventura, A.1
-
154
-
-
84555173651
-
Molecular programming of B cell memory
-
McHeyzer-Williams, M., Okitsu, S., Wang, N., & McHeyzer-Williams, L. Molecular programming of B cell memory. Nat. Rev. Immunol. 12, 24-34 (2012).
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 24-34
-
-
McHeyzer-Williams, M.1
Okitsu, S.2
Wang, N.3
McHeyzer-Williams, L.4
-
155
-
-
84873536866
-
IL 21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp 1 in human B cells
-
Ding, B. B., Bi, E., Chen, H., Yu, J. J., & Ye, B. H. IL 21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp 1 in human B cells. J. Immunol. 190, 1827-1836 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 1827-1836
-
-
Ding, B.B.1
Bi, E.2
Chen, H.3
Yu, J.J.4
Ye, B.H.5
-
156
-
-
84923829724
-
The generation of antibody-secreting plasma cells
-
Nutt, S. L., Hodgkin, P. D., Tarlinton, D. M., & Corcoran, L. M. The generation of antibody-secreting plasma cells. Nat. Rev. Immunol. 15, 160-171 (2015).
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 160-171
-
-
Nutt, S.L.1
Hodgkin, P.D.2
Tarlinton, D.M.3
Corcoran, L.M.4
-
157
-
-
84862889421
-
BLIMP 1 and STAT3 counterregulate microRNA 21 during plasma cell differentiation
-
Barnes, N. A., Stephenson, S., Cocco, M., Tooze, R. M., & Doody, G. M. BLIMP 1 and STAT3 counterregulate microRNA 21 during plasma cell differentiation. J. Immunol. 189, 253-260 (2012).
-
(2012)
J. Immunol.
, vol.189
, pp. 253-260
-
-
Barnes, N.A.1
Stephenson, S.2
Cocco, M.3
Tooze, R.M.4
Doody, G.M.5
-
158
-
-
84908252748
-
The miR 155 PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation
-
Lu, D. et al. The miR 155 PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation. J. Exp. Med. 211, 2183-2198 (2014).
-
(2014)
J. Exp. Med.
, vol.211
, pp. 2183-2198
-
-
Lu, D.1
-
159
-
-
84927041623
-
MiR 148a promotes plasma cell differentiation and targets the germinal center transcription factors Mitf and Bach2
-
Porstner, M. et al. miR 148a promotes plasma cell differentiation and targets the germinal center transcription factors Mitf and Bach2. Eur. J. Immunol. 45, 1206-1215 (2015).
-
(2015)
Eur. J. Immunol.
, vol.45
, pp. 1206-1215
-
-
Porstner, M.1
-
160
-
-
41449093809
-
B cell receptor activation induces BIC/miR 155 expression through a conserved AP 1 element
-
Yin, Q., Wang, X., McBride, J., Fewell, C., & Flemington, E. B cell receptor activation induces BIC/miR 155 expression through a conserved AP 1 element. J. Biol. Chem. 283, 2654-2662 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 2654-2662
-
-
Yin, Q.1
Wang, X.2
McBride, J.3
Fewell, C.4
Flemington, E.5
-
161
-
-
84924551273
-
NF κb/STAT5/miR 155 network targets PU.1 in FLT3 ITD-driven acute myeloid leukemia
-
Gerloff, D. et al. NF κB/STAT5/miR 155 network targets PU.1 in FLT3 ITD-driven acute myeloid leukemia. Leukemia 29, 535-547 (2015).
-
(2015)
Leukemia
, vol.29
, pp. 535-547
-
-
Gerloff, D.1
-
162
-
-
84959076294
-
The microRNA miR 148a functions as a critical regulator of B cell tolerance and autoimmunity
-
Gonzalez-Martin, A. et al. The microRNA miR 148a functions as a critical regulator of B cell tolerance and autoimmunity. Nat. Immunol. http://dx.doi.org/ 10.1038/ni.3385 (2016).
-
(2016)
Nat. Immunol.
-
-
Gonzalez-Martin, A.1
-
163
-
-
77954263256
-
MicroRNA 125b inhibition of B cell differentiation in germinal centers
-
Gururajan, M. et al. MicroRNA 125b inhibition of B cell differentiation in germinal centers. Int. Immunol. 22, 583-592 (2010).
-
(2010)
Int. Immunol.
, vol.22
, pp. 583-592
-
-
Gururajan, M.1
-
164
-
-
84856254706
-
B-1 B cell development in the fetus and adult
-
Montecino-Rodriguez, E., & Dorshkind, K. B-1 B cell development in the fetus and adult. Immunity 36, 13-21 (2012).
-
(2012)
Immunity
, vol.36
, pp. 13-21
-
-
Montecino-Rodriguez, E.1
Dorshkind, K.2
-
165
-
-
84928239791
-
Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a
-
Zhou, Y. et al. Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a. J. Exp. Med. 212, 569-580 (2015).
-
(2015)
J. Exp. Med.
, vol.212
, pp. 569-580
-
-
Zhou, Y.1
-
166
-
-
84931281751
-
Altered lymphopoiesis and immunodeficiency in miR 142 null mice
-
Palsson-McDermott, E. M. et al. Altered lymphopoiesis and immunodeficiency in miR 142 null mice. Proc. Natl Acad. Sci. USA 125, 3720-3730 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.125
, pp. 3720-3730
-
-
Palsson-McDermott, E.M.1
-
167
-
-
79958257077
-
MiR 146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
-
Boldin, M. P. et al. miR 146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J. Exp. Med. 208, 1189-1201 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1189-1201
-
-
Boldin, M.P.1
-
168
-
-
34247584465
-
Requirement of bic/microRNA 155 for normal immune function
-
Rodriguez, A. et al. Requirement of bic/microRNA 155 for normal immune function. Science 316, 608-611 (2007).
-
(2007)
Science
, vol.316
, pp. 608-611
-
-
Rodriguez, A.1
-
169
-
-
84875788209
-
MiR 155: An ancient regulator of the immune system
-
Vigorito, E. Kohlhaas, S., Lu, D., & Leyland, R. miR 155: an ancient regulator of the immune system. Immunol. Rev. 253, 146-157 (2013).
-
(2013)
Immunol. Rev.
, vol.253
, pp. 146-157
-
-
Vigorito Kohlhaas E, S.1
Lu, D.2
Leyland, R.3
-
170
-
-
37049002638
-
MicroRNA 155 regulates the generation of immunoglobulin class-switched plasma cells
-
Vigorito, E. et al. microRNA 155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity 27, 847-859 (2007).
-
(2007)
Immunity
, vol.27
, pp. 847-859
-
-
Vigorito, E.1
-
171
-
-
84862865669
-
Immunoglobulin class-switch DNA recombination: Induction, targeting and beyond
-
Xu, Z., Zan, H., Pone, E. J., Mai, T., & Casali, P. Immunoglobulin class-switch DNA recombination: induction, targeting and beyond. Nat. Rev. Immunol. 12, 517-531 (2012).
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 517-531
-
-
Xu, Z.1
Zan, H.2
Pone, E.J.3
Mai, T.4
Casali, P.5
-
172
-
-
43049178852
-
MicroRNA 155 is a negative regulator of activation-induced cytidine deaminase
-
Teng, G. et al. MicroRNA 155 is a negative regulator of activation-induced cytidine deaminase. Immunity 28, 621-629 (2008).
-
(2008)
Immunity
, vol.28
, pp. 621-629
-
-
Teng, G.1
-
173
-
-
0037881911
-
Constitutive expression of AID leads to tumorigenesis
-
Okazaki, I. M. et al. Constitutive expression of AID leads to tumorigenesis. J. Exp. Med. 197, 1173-1181 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1173-1181
-
-
Okazaki, I.M.1
-
174
-
-
53349129731
-
MiR 181b negatively regulates activation-induced cytidine deaminase in B cells
-
de Yebenes, V. G. et al. miR 181b negatively regulates activation-induced cytidine deaminase in B cells. J. Exp. Med. 205, 2199-2206 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2199-2206
-
-
De Yebenes, V.G.1
-
175
-
-
84884262682
-
MiR 210 is induced by Oct 2, regulates B cells, and inhibits autoantibody production
-
Mok, Y. et al. MiR 210 is induced by Oct 2, regulates B cells, and inhibits autoantibody production. J. Immunol. 191, 3037-3048 (2013).
-
(2013)
J. Immunol.
, vol.191
, pp. 3037-3048
-
-
Mok, Y.1
-
176
-
-
84904114788
-
MiR 217 is an oncogene that enhances the germinal center reaction
-
de Yebenes, V. G. et al. miR 217 is an oncogene that enhances the germinal center reaction. Blood 124, 229-239 (2014).
-
(2014)
Blood
, vol.124
, pp. 229-239
-
-
De Yebenes, V.G.1
-
177
-
-
0036582215
-
T cell development and the CD4 CD8 lineage decision
-
Germain, R. N. T cell development and the CD4 CD8 lineage decision. Nat. Rev. Immunol. 2, 309-322 (2002).
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 309-322
-
-
Germain, R.N.1
-
178
-
-
84904966072
-
Developmental gene networks: A triathlon on the course to T cell identity
-
Yui, M. A., & Rothenberg, E. V. Developmental gene networks: a triathlon on the course to T cell identity. Nat. Rev. Immunol. 14, 529-545 (2014).
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 529-545
-
-
Yui, M.A.1
Rothenberg, E.V.2
-
179
-
-
24644489402
-
MicroRNA profiling of the murine hematopoietic system
-
Monticelli, S. et al. MicroRNA profiling of the murine hematopoietic system. Genome Biol. 6, R71 (2005).
-
(2005)
Genome Biol.
, vol.6
, pp. R71
-
-
Monticelli, S.1
-
180
-
-
38349016948
-
MiRNA profiling of naive, effector and memory CD8 T cells
-
Wu, H. et al. miRNA profiling of naive, effector and memory CD8 T cells. PLoS ONE 2, e1020 (2007).
-
(2007)
PLoS ONE
, vol.2
, pp. e1020
-
-
Wu, H.1
-
181
-
-
20844432885
-
T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer
-
Cobb, B. S. et al. T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer. J. Exp. Med. 201, 1367-1373 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1367-1373
-
-
Cobb, B.S.1
-
182
-
-
22944433872
-
Aberrant T cell differentiation in the absence of Dicer
-
Muljo, S. A. et al. Aberrant T cell differentiation in the absence of Dicer. J. Exp. Med. 202, 261-269 (2005).
-
(2005)
J. Exp. Med.
, vol.202
, pp. 261-269
-
-
Muljo, S.A.1
-
183
-
-
79959842615
-
Modulation of microRNA expression in human T cell development: Targeting of NOTCH3 by miR 150
-
Ghisi, M. et al. Modulation of microRNA expression in human T cell development: targeting of NOTCH3 by miR 150. Blood 117, 7053-7062 (2011).
-
(2011)
Blood
, vol.117
, pp. 7053-7062
-
-
Ghisi, M.1
-
184
-
-
33947721625
-
MiR 181a is an intrinsic modulator of T cell sensitivity and selection
-
Li, Q. J. et al. miR 181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129, 147-161 (2007).
-
(2007)
Cell
, vol.129
, pp. 147-161
-
-
Li, Q.J.1
-
185
-
-
41549134361
-
Th17 cell differentiation: The long and winding road
-
McGeachy, M. J., & Cua, D. J. Th17 cell differentiation: the long and winding road. Immunity 28, 445-453 (2008).
-
(2008)
Immunity
, vol.28
, pp. 445-453
-
-
McGeachy, M.J.1
Cua, D.J.2
-
186
-
-
84879123259
-
MicroRNA 155 confers encephalogenic potential to Th17 cells by promoting effector gene expression
-
Hu, R. et al. MicroRNA 155 confers encephalogenic potential to Th17 cells by promoting effector gene expression. J. Immunol. 190, 5972-5980 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 5972-5980
-
-
Hu, R.1
-
187
-
-
84867584246
-
MicroRNA 155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1
-
Yao, R. et al. MicroRNA 155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1. PLoS ONE 7, e46082 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e46082
-
-
Yao, R.1
-
188
-
-
84924028501
-
MicroRNA 21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis
-
Murugaiyan, G. et al. MicroRNA 21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis. J. Clin. Invest. 125, 1069-1080 (2015).
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 1069-1080
-
-
Murugaiyan, G.1
-
189
-
-
84861207616
-
MicroRNA 301a regulation of a T helper 17 immune response controls autoimmune demyelination
-
Mycko, M. P. et al. MicroRNA 301a regulation of a T helper 17 immune response controls autoimmune demyelination. Proc. Natl Acad. Sci. USA 109, E1248-E1257 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. E1248-E1257
-
-
Mycko, M.P.1
-
190
-
-
70449716915
-
MicroRNA miR 326 regulates TH 17 differentiation and is associated with the pathogenesis of multiple sclerosis
-
Du, C. et al. MicroRNA miR 326 regulates TH 17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat. Immunol. 10, 1252-1259 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1252-1259
-
-
Du, C.1
-
191
-
-
84902193953
-
MiR 20b suppresses Th17 differentiation and the pathogenesis of experimental autoimmune encephalomyelitis by targeting ROR?t and STAT3
-
Zhu, E. et al. miR 20b suppresses Th17 differentiation and the pathogenesis of experimental autoimmune encephalomyelitis by targeting ROR?t and STAT3. J. Immunol. 192, 5599-5609 (2014).
-
(2014)
J. Immunol.
, vol.192
, pp. 5599-5609
-
-
Zhu, E.1
-
192
-
-
84880352166
-
Aryl hydrocarbon receptor-mediated induction of the microRNA 132/212 cluster promotes interleukin 17 producing T helper cell differentiation
-
Nakahama, T. et al. Aryl hydrocarbon receptor-mediated induction of the microRNA 132/212 cluster promotes interleukin 17 producing T helper cell differentiation. Proc. Natl Acad. Sci. USA 110, 11964-11969 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 11964-11969
-
-
Nakahama, T.1
-
193
-
-
84933277411
-
An allelic series of miR 17 approximately 92 mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron
-
Han, Y. C., & Vidigal, J. A. An allelic series of miR 17 approximately 92 mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron. Nat. Genet. 47, 766-775 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 766-775
-
-
Han, Y.C.1
Vidigal, J.A.2
-
194
-
-
81555196345
-
Molecular dissection of the miR 17 92 cluster?s critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation
-
Jiang, S. et al. Molecular dissection of the miR 17 92 cluster?s critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation. Blood 118, 5487-5497 (2011).
-
(2011)
Blood
, vol.118
, pp. 5487-5497
-
-
Jiang, S.1
-
195
-
-
77958149675
-
The microRNA miR 182 is induced by IL 2 and promotes clonal expansion of activated helper T lymphocytes
-
Stittrich, A. B. et al. The microRNA miR 182 is induced by IL 2 and promotes clonal expansion of activated helper T lymphocytes. Nat. Immunol. 11, 1057-1062 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 1057-1062
-
-
Stittrich, A.B.1
-
196
-
-
77955508072
-
Costimulation-dependent expression of microRNA 214 increases the ability of T cells to proliferate by targeting Pten
-
Jindra, P. T., Bagley, J., Godwin, J. G., & Iacomini, J. Costimulation-dependent expression of microRNA 214 increases the ability of T cells to proliferate by targeting Pten. J. Immunol. 185, 990-997 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 990-997
-
-
Jindra, P.T.1
Bagley, J.2
Godwin, J.G.3
Iacomini, J.4
-
197
-
-
84960335745
-
MiR 23 approximately 27 approximately 24 clusters control effector T cell differentiation and function
-
Cho, S. et al. miR 23 approximately 27 approximately 24 clusters control effector T cell differentiation and function. J. Exp. Med. 213, 235-249 (2016).
-
(2016)
J. Exp. Med.
, vol.213
, pp. 235-249
-
-
Cho, S.1
-
198
-
-
84956608529
-
MicroRNAs 24 and 27 suppress allergic inflammation and target a network of regulators of T helper 2 cell-Associated cytokine production. Immunity
-
Pua, H. H. et al. MicroRNAs 24 and 27 suppress allergic inflammation and target a network of regulators of T helper 2 cell-Associated cytokine production. Immunity http://dx.doi.org/10.1016/ j.immuni.2016.01.003 (2016).
-
(2016)
J.immuni.
-
-
Pua, H.H.1
-
199
-
-
84908146717
-
MiR 155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation
-
Hu, R. et al. miR 155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation. Immunity 41, 605-619 (2014).
-
(2014)
Immunity
, vol.41
, pp. 605-619
-
-
Hu, R.1
-
200
-
-
84871694595
-
Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity
-
Huffaker, T. B. et al. Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity. Cell Rep. 2, 1697-1709 (2012).
-
(2012)
Cell Rep.
, vol.2
, pp. 1697-1709
-
-
Huffaker, T.B.1
-
201
-
-
84866354593
-
MiR 146a controls the resolution of T cell responses in mice
-
Yang, L. et al. miR 146a controls the resolution of T cell responses in mice. J. Exp. Med. 209, 1655-1670 (2012).
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1655-1670
-
-
Yang, L.1
-
202
-
-
77956632634
-
Function of miR 146a in controlling Treg cell-mediated regulation of Th1 responses
-
Lu, L. F. et al. Function of miR 146a in controlling Treg cell-mediated regulation of Th1 responses. Cell 142, 914-929 (2010).
-
(2010)
Cell
, vol.142
, pp. 914-929
-
-
Lu, L.F.1
-
203
-
-
84880767787
-
MicroRNAs of the miR 17 approximately 92 family are critical regulators of TFH differentiation
-
Kang, S. G. et al. MicroRNAs of the miR 17 approximately 92 family are critical regulators of TFH differentiation. Nat. Immunol. 14, 849-857 (2013).
-
(2013)
Nat. Immunol.
, vol.14
, pp. 849-857
-
-
Kang, S.G.1
-
204
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin, G. A., & Croce, C. M. MicroRNA signatures in human cancers. Nature reviews. Cancer 6, 857-866 (2006).
-
(2006)
Nature Reviews. Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
205
-
-
4143142117
-
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
-
Calin, G. A. et al. MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc. Natl Acad. Sci. USA 101, 11755-11760 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 11755-11760
-
-
Calin, G.A.1
-
206
-
-
84877094834
-
MicroRNA profiling can classify acute leukemias of ambiguous lineage as either acute myeloid leukemia or acute lymphoid leukemia
-
de Leeuw, D. C. et al. MicroRNA profiling can classify acute leukemias of ambiguous lineage as either acute myeloid leukemia or acute lymphoid leukemia. Clin. Cancer Res. 19, 2187-2196 (2013).
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 2187-2196
-
-
De Leeuw, D.C.1
-
207
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu, J. et al. MicroRNA expression profiles classify human cancers. Nature 435, 834-838 (2005).
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
-
208
-
-
84856758666
-
MicroRNAs in acute leukemia: From biological players to clinical contributors
-
Schotte, D., Pieters, R., & Den Boer, M. L. MicroRNAs in acute leukemia: from biological players to clinical contributors. Leukemia 26, 1-12 (2012).
-
(2012)
Leukemia
, vol.26
, pp. 1-12
-
-
Schotte, D.1
Pieters, R.2
Den Boer, M.L.3
-
209
-
-
42449141513
-
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia
-
Garzon, R. et al. MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia. Blood 111, 3183-3189 (2008).
-
(2008)
Blood
, vol.111
, pp. 3183-3189
-
-
Garzon, R.1
-
210
-
-
84930396449
-
MicroRNA regulation of lymphocyte tolerance and autoimmunity
-
Simpson, L. J., & Ansel, K. M. MicroRNA regulation of lymphocyte tolerance and autoimmunity. J. Clin. Invest. 125, 2242-2249 (2015).
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 2242-2249
-
-
Simpson, L.J.1
Ansel, K.M.2
-
211
-
-
84884702252
-
The role of miRNA in inflammation and autoimmunity
-
Singh, R. P. et al. The role of miRNA in inflammation and autoimmunity. Autoimmun. Rev. 12, 1160-1165 (2013).
-
(2013)
Autoimmun. Rev.
, vol.12
, pp. 1160-1165
-
-
Singh, R.P.1
-
212
-
-
78650736233
-
MicroRNA miR 125b causes leukemia
-
Bousquet, M., Harris, M. H., Zhou, B., & Lodish, H. F. MicroRNA miR 125b causes leukemia. Proc. Natl Acad. Sci. USA 107, 21558-21563 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 21558-21563
-
-
Bousquet, M.1
Harris, M.H.2
Zhou, B.3
Lodish, H.F.4
-
213
-
-
83555166166
-
Emu/miR 125b transgenic mice develop lethal B cell malignancies
-
Enomoto, Y. et al. Emu/miR 125b transgenic mice develop lethal B cell malignancies. Leukemia 25, 1849-1856 (2011).
-
(2011)
Leukemia
, vol.25
, pp. 1849-1856
-
-
Enomoto, Y.1
-
214
-
-
84901828594
-
MicroRNA 28 controls cell proliferation and is down-regulated in B cell lymphomas
-
Schneider, C. et al. MicroRNA 28 controls cell proliferation and is down-regulated in B cell lymphomas. Proc. Natl Acad. Sci. USA 111, 8185-8190 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 8185-8190
-
-
Schneider, C.1
-
215
-
-
84887310173
-
B cell malignancies in microRNA Emu-miR 17~92 transgenic mice
-
Sandhu, S. K. et al. B cell malignancies in microRNA Emu-miR 17~92 transgenic mice. Proc. Natl Acad. Sci. USA 110, 18208-18213 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 18208-18213
-
-
Sandhu, S.K.1
-
216
-
-
77951757309
-
The miR 17 92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression
-
Wong, P. et al. The miR 17 92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression. Cancer Res. 70, 3833-3842 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 3833-3842
-
-
Wong, P.1
-
217
-
-
20444467290
-
A microRNA polycistron as a potential human oncogene
-
He, L. et al. A microRNA polycistron as a potential human oncogene. Nature 435, 828-833 (2005).
-
(2005)
Nature
, vol.435
, pp. 828-833
-
-
He, L.1
-
218
-
-
39749163245
-
Lymphoproliferative disease and autoimmunity in mice with increased miR 17 92 expression in lymphocytes
-
Xiao, C. et al. Lymphoproliferative disease and autoimmunity in mice with increased miR 17 92 expression in lymphocytes. Nat. Immunol. 9, 405-414 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 405-414
-
-
Xiao, C.1
-
219
-
-
84884263191
-
The TAL1 complex targets the FBXW7 tumor suppressor by activating miR 223 in human T cell acute lymphoblastic leukemia
-
Mansour, M. R. et al. The TAL1 complex targets the FBXW7 tumor suppressor by activating miR 223 in human T cell acute lymphoblastic leukemia. J. Exp. Med. 210, 1545-1557 (2013).
-
(2013)
J. Exp. Med.
, vol.210
, pp. 1545-1557
-
-
Mansour, M.R.1
-
220
-
-
70350778443
-
An epigenetic switch involving NF κb, Lin28, Let 7 MicroRNA, and IL6 links inflammation to cell transformation
-
Iliopoulos, D., Hirsch, H. A., & Struhl, K. An epigenetic switch involving NF κB, Lin28, Let 7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 139, 693-706 (2009).
-
(2009)
Cell
, vol.139
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
221
-
-
84894495362
-
STAT3 induction of miR 146b forms a feedback loop to inhibit the NF κb to IL 6 signaling axis and STAT3 driven cancer phenotypes
-
ra11
-
Xiang, M. et al. STAT3 induction of miR 146b forms a feedback loop to inhibit the NF κB to IL 6 signaling axis and STAT3 driven cancer phenotypes. Sci. Signal. 7, ra11 (2014).
-
(2014)
Sci. Signal.
, vol.7
-
-
Xiang, M.1
-
222
-
-
77958495102
-
MicroRNA 155 promotes autoimmune inflammation by enhancing inflammatory T cell development
-
Oconnell, R. M. et al. MicroRNA 155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity 33, 607-619 (2010).
-
(2010)
Immunity
, vol.33
, pp. 607-619
-
-
Oconnell, R.M.1
-
223
-
-
79960595150
-
MicroRNA 155 as a proinflammatory regulator in clinical and experimental arthritis
-
Kurowska-Stolarska, M. et al. MicroRNA 155 as a proinflammatory regulator in clinical and experimental arthritis. Proc. Natl Acad. Sci. USA 108, 11193-11198 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 11193-11198
-
-
Kurowska-Stolarska, M.1
-
224
-
-
84907906605
-
Quantitative and stoichiometric analysis of the microRNA content of exosomes
-
Chevillet, J. R. et al. Quantitative and stoichiometric analysis of the microRNA content of exosomes. Proc. Natl Acad. Sci. USA 111, 14888-14893 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 14888-14893
-
-
Chevillet, J.R.1
-
225
-
-
84922273505
-
In vivo delivery of miRNAs for cancer therapy: Challenges and strategies
-
Chen, Y., Gao, D. Y., & Huang, L. In vivo delivery of miRNAs for cancer therapy: challenges and strategies. Adv. Drug Delivery Rev. 81, 128-141 (2015).
-
(2015)
Adv. Drug Delivery Rev.
, vol.81
, pp. 128-141
-
-
Chen, Y.1
Gao, D.Y.2
Huang, L.3
-
226
-
-
84877258007
-
Treatment of HCV infection by targeting microRNA
-
Janssen, H. L. et al. Treatment of HCV infection by targeting microRNA. New Engl. J. Med. 368, 1685-1694 (2013).
-
(2013)
New Engl. J. Med.
, vol.368
, pp. 1685-1694
-
-
Janssen, H.L.1
-
227
-
-
84905503012
-
Therapeutic targeting of microRNAs: Current status and future challenges
-
Li, Z., & Rana, T. M. Therapeutic targeting of microRNAs: current status and future challenges. Nat. Rev. Drug Discov. 13, 622-638 (2014).
-
(2014)
Nat. Rev. Drug Discov.
, vol.13
, pp. 622-638
-
-
Li, Z.1
Rana, T.M.2
-
228
-
-
84887101163
-
Micrornas and other non-coding rnas as targets for anticancer drug development
-
Ling, H., Fabbri, M., & Calin, G. A. MicroRNAs and other non-coding RNAs as targets for anticancer drug development. Nat. Rev. Drug Discov. 12, 847-865 (2013).
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 847-865
-
-
Ling, H.1
Fabbri, M.2
Calin, G.A.3
-
229
-
-
84890212376
-
TALEN-based knockout library for human microRNAs
-
Kim, Y. K. et al. TALEN-based knockout library for human microRNAs. Nat. Struct. Mol. Biol. 20, 1458-1464 (2013).
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1458-1464
-
-
Kim, Y.K.1
-
230
-
-
84901418880
-
A TALEN-based strategy for efficient bi allelic miRNA ablation in human cells
-
Uhde-Stone, C. et al. A TALEN-based strategy for efficient bi allelic miRNA ablation in human cells. RNA 20, 948-955 (2014).
-
(2014)
RNA
, vol.20
, pp. 948-955
-
-
Uhde-Stone, C.1
-
231
-
-
84877105430
-
Targeting human microRNA genes using engineered Tal-effector nucleases (TALENs)
-
Hu, R., Wallace, J., Dahlem, T. J., Grunwald, D. J., & Oconnell, R. M. Targeting human microRNA genes using engineered Tal-effector nucleases (TALENs). PLoS ONE 8, e63074 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e63074
-
-
Hu, R.1
Wallace, J.2
Dahlem, T.J.3
Grunwald, D.J.4
Oconnell, R.M.5
-
232
-
-
84936077333
-
Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines
-
Ho, T. T. et al. Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines. Nucleic Acids Res. 43, e17 (2015).
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. e17
-
-
Ho, T.T.1
-
233
-
-
84893819419
-
Sequence-specific inhibition of microRNA via CRISPR/CRISPRi system
-
Zhao, Y. et al. Sequence-specific inhibition of microRNA via CRISPR/CRISPRi system. Scientif. Rep. 4, 3943 (2014).
-
(2014)
Scientif. Rep.
, vol.4
, pp. 3943
-
-
Zhao, Y.1
-
234
-
-
67749132423
-
Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
-
Chi, S. W., Zang, J. B., Mele, A., & Darnell, R. B. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460, 479-486 (2009).
-
(2009)
Nature
, vol.460
, pp. 479-486
-
-
Chi, S.W.1
Zang, J.B.2
Mele, A.3
Darnell, R.B.4
-
235
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
Friedman, R. C., Farh, K. K., Burge, C. B., & Bartel, D. P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 19, 92-105 (2009).
-
(2009)
Genome Res.
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
Bartel, D.P.4
-
236
-
-
77955644289
-
Mammalian microRNAs predominantly act to decrease target mRNA levels
-
Guo, H., Ingolia, N. T., Weissman, J. S., & Bartel, D. P. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466, 835-840 (2010).
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
237
-
-
84904985459
-
Regulation of microRNA biogenesis
-
Ha, M., & Kim, V. N. Regulation of microRNA biogenesis. Nat. Rev. Mol. Cell Biol. 15, 509-524 (2014).
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 509-524
-
-
Ha, M.1
Kim, V.N.2
-
238
-
-
3042767202
-
MicroRNAs: Small RNAs with a big role in gene regulation
-
He, L., & Hannon, G. J. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 5, 522-531 (2004).
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
239
-
-
84940502214
-
Predicting effective microRNA target sites in mammalian mRNAs
-
Agarwal, V., Bell, G. W., Nam, J. W., & Bartel, D. P. Predicting effective microRNA target sites in mammalian mRNAs. eLife 4, http://dx.doi.org/ 10.7554/eLife.05005 (2015).
-
(2015)
ELife
, vol.4
-
-
Agarwal, V.1
Bell, G.W.2
Nam, J.W.3
Bartel, D.P.4
-
240
-
-
70349439320
-
MiR 147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses
-
Liu, G. et al. miR 147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses. Proc. Natl Acad. Sci. USA 106, 15819-15824 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 15819-15824
-
-
Liu, G.1
-
241
-
-
84872722692
-
Regulation of TLR2 mediated tolerance and cross-Tolerance through IRAK4 modulation by miR 132 and miR 212
-
Nahid, M. A. et al. Regulation of TLR2 mediated tolerance and cross-Tolerance through IRAK4 modulation by miR 132 and miR 212. J. Immunol. 190, 1250-1263 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 1250-1263
-
-
Nahid, M.A.1
-
242
-
-
46449128469
-
SMAD proteins control DROSHA-mediated microRNA maturation
-
Davis, B. N., Hilyard, A. C., Lagna, G., & Hata, A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 454, 56-61 (2008).
-
(2008)
Nature
, vol.454
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
243
-
-
67649277689
-
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs
-
Trabucchi, M. et al. The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature 459, 1010-1014 (2009).
-
(2009)
Nature
, vol.459
, pp. 1010-1014
-
-
Trabucchi, M.1
-
244
-
-
68749102148
-
TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation
-
Heo, I. et al. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell 138, 696-708 (2009).
-
(2009)
Cell
, vol.138
, pp. 696-708
-
-
Heo, I.1
-
245
-
-
34547955952
-
A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway
-
O?Carroll, D. et al. A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway. Genes Dev. 21, 1999-2004 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 1999-2004
-
-
Ocarroll, D.1
-
246
-
-
43449090367
-
MicroRNA 10a binds the 5?UTR of ribosomal protein mRNAs and enhances their translation
-
Orom, U. A., Nielsen, F. C., & Lund, A. H. MicroRNA 10a binds the 5?UTR of ribosomal protein mRNAs and enhances their translation. Mol. Cell 30, 460-471 (2008).
-
(2008)
Mol. Cell
, vol.30
, pp. 460-471
-
-
Orom, U.A.1
Nielsen, F.C.2
Lund, A.H.3
-
247
-
-
40349094597
-
MicroRNA 373 induces expression of genes with complementary promoter sequences
-
Place, R. F., Li, L. C., Pookot, D., Noonan, E. J., & Dahiya, R. MicroRNA 373 induces expression of genes with complementary promoter sequences. Proc. Natl Acad. Sci. USA 105, 1608-1613 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 1608-1613
-
-
Place, R.F.1
Li, L.C.2
Pookot, D.3
Noonan, E.J.4
Dahiya, R.5
-
248
-
-
36749026906
-
Switching from repression to activation: MicroRNAs can up regulate translation
-
Vasudevan, S., Tong, Y., & Steitz, J. A. Switching from repression to activation: microRNAs can up regulate translation. Science 318, 1931-1934 (2007).
-
(2007)
Science
, vol.318
, pp. 1931-1934
-
-
Vasudevan, S.1
Tong, Y.2
Steitz, J.A.3
-
249
-
-
84940234906
-
MicroRNAs and RNA-binding proteins: A complex network of interactions and reciprocal regulations in cancer
-
Ciafre, S. A., & Galardi, S. microRNAs and RNA-binding proteins: a complex network of interactions and reciprocal regulations in cancer. RNA Biol. 10, 935-942 (2013).
-
(2013)
RNA Biol.
, vol.10
, pp. 935-942
-
-
Ciafre, S.A.1
Galardi, S.2
-
250
-
-
84868153864
-
Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let 7 microRNAs
-
Heo, I. et al. Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let 7 microRNAs. Cell 151, 521-532 (2012).
-
(2012)
Cell
, vol.151
, pp. 521-532
-
-
Heo, I.1
-
251
-
-
81855228621
-
Molecular basis for interaction of let 7 microRNAs with Lin28
-
Nam, Y., Chen, C., Gregory, R. I., Chou, J. J., & Sliz, P. Molecular basis for interaction of let 7 microRNAs with Lin28. Cell 147, 1080-1091 (2011).
-
(2011)
Cell
, vol.147
, pp. 1080-1091
-
-
Nam, Y.1
Chen, C.2
Gregory, R.I.3
Chou, J.J.4
Sliz, P.5
-
252
-
-
80052041185
-
MicroRNA regulation by RNA-binding proteins and its implications for cancer
-
van Kouwenhove, M., Kedde, M., & Agami, R. MicroRNA regulation by RNA-binding proteins and its implications for cancer. Nat. Rev. Cancer 11, 644-656 (2011).
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 644-656
-
-
Van Kouwenhove, M.1
Kedde, M.2
Agami, R.3
-
253
-
-
84858446579
-
MicroRNAs and their targets: Recognition, regulation and an emerging reciprocal relationship
-
Pasquinelli, A. E. MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat. Rev. Genet. 13, 271-282 (2012).
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 271-282
-
-
Pasquinelli, A.E.1
-
254
-
-
79961170994
-
A ceRNA hypo thesis: The Rosetta Stone of a hidden RNA language?
-
Salmena, L., Poliseno, L., Tay, Y., Kats, L., & Pandolfi, P. P. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?. Cell 146, 353-358 (2011).
-
(2011)
Cell
, vol.146
, pp. 353-358
-
-
Salmena, L.1
Poliseno, L.2
Tay, Y.3
Kats, L.4
Pandolfi, P.P.5
-
255
-
-
84892573723
-
The multilayered complexity of ceRNA crosstalk and competition
-
Tay, Y., Rinn, J., & Pandolfi, P. P. The multilayered complexity of ceRNA crosstalk and competition. Nature 505, 344-352 (2014).
-
(2014)
Nature
, vol.505
, pp. 344-352
-
-
Tay, Y.1
Rinn, J.2
Pandolfi, P.P.3
|