-
1
-
-
0036720398
-
The roles of FLT3 in hematopoiesis and leukemia
-
Gilliland DG, Griffin JD. The roles of FLT3 in hematopoiesis and leukemia. Blood 2002; 100: 1532-1542.
-
(2002)
Blood
, vol.100
, pp. 1532-1542
-
-
Gilliland, D.G.1
Griffin, J.D.2
-
2
-
-
32144437947
-
Mutant FLT3 signaling contributes to a block in myeloid differentiation
-
Zheng R, Small D. Mutant FLT3 signaling contributes to a block in myeloid differentiation. Leuk Lymphoma 2005; 46: 1679-1687.
-
(2005)
Leuk Lymphoma
, vol.46
, pp. 1679-1687
-
-
Zheng, R.1
Small, D.2
-
3
-
-
14644438570
-
Risk assessment in patients with acute myeloid leukemia and a normal karyotype
-
Bienz M, Ludwig M, Leibundgut EO, Mueller BU, Ratschiller D, Solenthaler M et al. Risk assessment in patients with acute myeloid leukemia and a normal karyotype. Clin Cancer Res 2005; 11: 1416-1424.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1416-1424
-
-
Bienz, M.1
Ludwig, M.2
Leibundgut, E.O.3
Mueller, B.U.4
Ratschiller, D.5
Solenthaler, M.6
-
4
-
-
22044448746
-
AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations
-
Choudhary C, Schwable J, Brandts C, Tickenbrock L, Sargin B, Kindler T et al. AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations. Blood 2005; 106: 265-273.
-
(2005)
Blood
, vol.106
, pp. 265-273
-
-
Choudhary, C.1
Schwable, J.2
Brandts, C.3
Tickenbrock, L.4
Sargin, B.5
Kindler, T.6
-
5
-
-
34347401419
-
Activation mechanisms of STAT5 by oncogenic Flt3-ITD
-
Choudhary C, Brandts C, Schwable J, Tickenbrock L, Sargin B, Ueker A et al. Activation mechanisms of STAT5 by oncogenic Flt3-ITD. Blood 2007; 110: 370-374.
-
(2007)
Blood
, vol.110
, pp. 370-374
-
-
Choudhary, C.1
Brandts, C.2
Schwable, J.3
Tickenbrock, L.4
Sargin, B.5
Ueker, A.6
-
6
-
-
0037838661
-
Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells
-
Spiekermann K, Bagrintseva K, Schwab R, Schmieja K, Hiddemann W. Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells. Clin Cancer Res 2003; 9: 2140-2150.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2140-2150
-
-
Spiekermann, K.1
Bagrintseva, K.2
Schwab, R.3
Schmieja, K.4
Hiddemann, W.5
-
7
-
-
0034598830
-
Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines
-
Hayakawa F, Towatari M, Kiyoi H, Tanimoto M, Kitamura T, Saito H et al. Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines. Oncogene 2000; 19: 624-631.
-
(2000)
Oncogene
, vol.19
, pp. 624-631
-
-
Hayakawa, F.1
Towatari, M.2
Kiyoi, H.3
Tanimoto, M.4
Kitamura, T.5
Saito, H.6
-
8
-
-
0033820091
-
Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation
-
Tse KF, Mukherjee G, Small D. Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation. Leukemia 2000; 14: 1766-1776.
-
(2000)
Leukemia
, vol.14
, pp. 1766-1776
-
-
Tse, K.F.1
Mukherjee, G.2
Small, D.3
-
9
-
-
22544482989
-
Targeting mutated protein tyrosine kinases and their signaling pathways in hematologic malignancies
-
Chalandon Y, Schwaller J. Targeting mutated protein tyrosine kinases and their signaling pathways in hematologic malignancies. Haematologica 2005; 90: 949-968.
-
(2005)
Haematologica
, vol.90
, pp. 949-968
-
-
Chalandon, Y.1
Schwaller, J.2
-
10
-
-
0037944120
-
Suppression of myeloid transcription factors and induction of STAT response genes by AML-speci fic Flt3 mutations
-
Mizuki M, Schwable J, Steur C, Choudhary C, Agrawal S, Sargin B et al. Suppression of myeloid transcription factors and induction of STAT response genes by AML-speci fic Flt3 mutations. Blood 2003; 101: 3164-3173.
-
(2003)
Blood
, vol.101
, pp. 3164-3173
-
-
Mizuki, M.1
Schwable, J.2
Steur, C.3
Choudhary, C.4
Agrawal, S.5
Sargin, B.6
-
11
-
-
33344455424
-
Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations
-
Radomska HS, Basseres DS, Zheng R, Zhang P, Dayaram T, Yamamoto Y et al. Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations. J Exp Med 2006; 203: 371-381.
-
(2006)
J Exp Med
, vol.203
, pp. 371-381
-
-
Radomska, H.S.1
Basseres, D.S.2
Zheng, R.3
Zhang, P.4
Dayaram, T.5
Yamamoto, Y.6
-
12
-
-
0034554796
-
Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways
-
Mizuki M, Fenski R, Halfter H, Matsumura I, Schmidt R, Muller C et al. Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways. Blood 2000; 96: 3907-3914.
-
(2000)
Blood
, vol.96
, pp. 3907-3914
-
-
Mizuki, M.1
Fenski, R.2
Halfter, H.3
Matsumura, I.4
Schmidt, R.5
Muller, C.6
-
13
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
23
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004 23; 116: 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
14
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros V. The functions of animal microRNAs. Nature 2004; 431: 350-355.
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
15
-
-
77950354353
-
Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia
-
Pulikkan JA, Dengler V, Peramangalam PS, Peer Zada AA, Muller-Tidow C, Bohlander SK et al. Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia. Blood 2010; 115: 1768-1778.
-
(2010)
Blood
, vol.115
, pp. 1768-1778
-
-
Pulikkan, J.A.1
Dengler, V.2
Peramangalam, P.S.3
Peer Zada, A.A.4
Muller-Tidow, C.5
Bohlander, S.K.6
-
16
-
-
84887776468
-
Transcription factor C/EBPalpha-induced microRNA-30c inactivates Notch1 during granulopoiesis and is downregulated in acute myeloid leukemia
-
Katzerke C, Madan V, Gerloff D, Brauer-Hartmann D, Hartmann JU, Wurm AA et al. Transcription factor C/EBPalpha-induced microRNA-30c inactivates Notch1 during granulopoiesis and is downregulated in acute myeloid leukemia. Blood 2013; 122: 2433-2442.
-
(2013)
Blood
, vol.122
, pp. 2433-2442
-
-
Katzerke, C.1
Madan, V.2
Gerloff, D.3
Brauer-Hartmann, D.4
Hartmann, J.U.5
Wurm, A.A.6
-
17
-
-
78650459322
-
C/EBPalpha regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations
-
Pulikkan JA, Peramangalam PS, Dengler V, Ho PA, Preudhomme C, Meshinchi S et al. C/EBPalpha regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations. Blood 2010; 116: 5638-5649.
-
(2010)
Blood
, vol.116
, pp. 5638-5649
-
-
Pulikkan, J.A.1
Peramangalam, P.S.2
Dengler, V.3
Ho, P.A.4
Preudhomme, C.5
Meshinchi, S.6
-
18
-
-
84856758666
-
MicroRNAs in acute leukemia: From biological players to clinical contributors
-
Schotte D, Pieters R, Den Boer ML. MicroRNAs in acute leukemia: from biological players to clinical contributors. Leukemia 2012; 26: 1-12.
-
(2012)
Leukemia
, vol.26
, pp. 1-12
-
-
Schotte, D.1
Pieters, R.2
Den Boer, M.L.3
-
19
-
-
41649119008
-
Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin
-
Garzon R, Garofalo M, Martelli MP, Briesewitz R, Wang L, Fernandez-Cymering C et al. Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin. Proc Natl Acad Sci USA 2008; 105: 3945-3950.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3945-3950
-
-
Garzon, R.1
Garofalo, M.2
Martelli, M.P.3
Briesewitz, R.4
Wang, L.5
Fernandez-Cymering, C.6
-
20
-
-
42449141513
-
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia
-
Garzon R, Volinia S, Liu CG, Fernandez-Cymering C, Palumbo T, Pichiorri F et al. MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia. Blood 2008; 111: 3183-3189.
-
(2008)
Blood
, vol.111
, pp. 3183-3189
-
-
Garzon, R.1
Volinia, S.2
Liu, C.G.3
Fernandez-Cymering, C.4
Palumbo, T.5
Pichiorri, F.6
-
21
-
-
46749108531
-
MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia
-
Jongen-Lavrencic M, Sun SM, Dijkstra MK, Valk PJ, Lowenberg B. MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia. Blood 2008; 111: 5078-5085.
-
(2008)
Blood
, vol.111
, pp. 5078-5085
-
-
Jongen-Lavrencic, M.1
Sun, S.M.2
Dijkstra, M.K.3
Valk, P.J.4
Lowenberg, B.5
-
22
-
-
77951540421
-
Differential expression of specific microRNA and their targets in acute myeloid leukemia
-
Cammarata G, Augugliaro L, Salemi D, Agueli C, La Rosa M, Dagnino L et al. Differential expression of specific microRNA and their targets in acute myeloid leukemia. Am J Hematol 2010; 85: 331-339.
-
(2010)
Am J Hematol
, vol.85
, pp. 331-339
-
-
Cammarata, G.1
Augugliaro, L.2
Salemi, D.3
Agueli, C.4
La Rosa, M.5
Dagnino, L.6
-
23
-
-
56649123539
-
Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-kappaB pathway
-
Gatto G, Rossi A, Rossi D, Kroening S, Bonatti S, Mallardo M. Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-kappaB pathway. Nucleic Acids Res 2008; 36: 6608-6619.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 6608-6619
-
-
Gatto, G.1
Rossi, A.2
Rossi, D.3
Kroening, S.4
Bonatti, S.5
Mallardo, M.6
-
24
-
-
55249124589
-
Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence
-
Lu F, Weidmer A, Liu CG, Volinia S, Croce CM, Lieberman PM. Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence. J Virol 2008; 82: 10436-10443.
-
(2008)
J Virol
, vol.82
, pp. 10436-10443
-
-
Lu, F.1
Weidmer, A.2
Liu, C.G.3
Volinia, S.4
Croce, C.M.5
Lieberman, P.M.6
-
25
-
-
34247584465
-
Requirement of bic/microRNA-155 for normal immune function
-
Rodriguez A, Vigorito E, Clare S, Warren MV, Couttet P, Soond DR et al. Requirement of bic/microRNA-155 for normal immune function. Science 2007; 316: 608-611.
-
(2007)
Science
, vol.316
, pp. 608-611
-
-
Rodriguez, A.1
Vigorito, E.2
Clare, S.3
Warren, M.V.4
Couttet, P.5
Soond, D.R.6
-
26
-
-
14844354250
-
Accumulation of miR-155 and BIC RNA in human B cell lymphomas
-
Eis PS, Tam W, Sun L, Chadburn A, Li Z, Gomez MF et al. Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci USA 2005; 102: 3627-3632.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3627-3632
-
-
Eis, P.S.1
Tam, W.2
Sun, L.3
Chadburn, A.4
Li, Z.5
Gomez, M.F.6
-
27
-
-
26044481464
-
BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas
-
Kluiver J, Poppema S, de Jong D, Blokzijl T, Harms G, Jacobs S et al. BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas. J Pathol 2005; 207: 243-249.
-
(2005)
J Pathol
, vol.207
, pp. 243-249
-
-
Kluiver, J.1
Poppema, S.2
De Jong, D.3
Blokzijl, T.4
Harms, G.5
Jacobs, S.6
-
28
-
-
49749107841
-
Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth
-
Wang X, Tang S, Le SY, Lu R, Rader JS, Meyers C et al. Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth. PLoS One 2008; 3: e2557.
-
(2008)
PLoS One
, vol.3
, pp. e2557
-
-
Wang, X.1
Tang, S.2
Le, S.Y.3
Lu, R.4
Rader, J.S.5
Meyers, C.6
-
29
-
-
33846813656
-
Expression profiling identifies microRNA signature in pancreatic cancer
-
Lee EJ, Gusev Y, Jiang J, Nuovo GJ, Lerner MR, Frankel WL et al. Expression profiling identifies microRNA signature in pancreatic cancer. Int J Cancer 2007; 120: 1046-1054.
-
(2007)
Int J Cancer
, vol.120
, pp. 1046-1054
-
-
Lee, E.J.1
Gusev, Y.2
Jiang, J.3
Nuovo, G.J.4
Lerner, M.R.5
Frankel, W.L.6
-
30
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006; 103: 2257-2261.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
Petrocca, F.6
-
31
-
-
23844555119
-
MicroRNA gene expression deregulation in human breast cancer
-
Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005; 65: 7065-7070.
-
(2005)
Cancer Res
, vol.65
, pp. 7065-7070
-
-
Iorio, M.V.1
Ferracin, M.2
Liu, C.G.3
Veronese, A.4
Spizzo, R.5
Sabbioni, S.6
-
32
-
-
41149130219
-
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder
-
O'Connell RM, Rao DS, Chaudhuri AA, Boldin MP, Taganov KD, Nicoll J et al. Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med 2008; 205: 585-594.
-
(2008)
J Exp Med
, vol.205
, pp. 585-594
-
-
O'Connell, R.M.1
Rao, D.S.2
Chaudhuri, A.A.3
Boldin, M.P.4
Taganov, K.D.5
Nicoll, J.6
-
33
-
-
84885424565
-
Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: MiR-155 upregulation independently identifies high-risk patients
-
Marcucci G, Maharry KS, Metzeler KH, Volinia S, Wu YZ, Mrozek K et al. Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients. J Clin Oncol 2013; 31: 2086-2093.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2086-2093
-
-
Marcucci, G.1
Maharry, K.S.2
Metzeler, K.H.3
Volinia, S.4
Wu, Y.Z.5
Mrozek, K.6
-
34
-
-
0035478329
-
STAT5 induces macrophage differentiation of M1 leukemia cells through activation of IL-6 production mediated by NF-kappaB p65
-
Kawashima T, Murata K, Akira S, Tonozuka Y, Minoshima Y, Feng S et al. STAT5 induces macrophage differentiation of M1 leukemia cells through activation of IL-6 production mediated by NF-kappaB p65. J Immunol 2001; 167: 3652-3660.
-
(2001)
J Immunol
, vol.167
, pp. 3652-3660
-
-
Kawashima, T.1
Murata, K.2
Akira, S.3
Tonozuka, Y.4
Minoshima, Y.5
Feng, S.6
-
35
-
-
4444268818
-
Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation
-
Cui Y, Riedlinger G, Miyoshi K, Tang W, Li C, Deng CX et al. Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation. Mol Cell Biol 2004; 24: 8037-8047.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8037-8047
-
-
Cui, Y.1
Riedlinger, G.2
Miyoshi, K.3
Tang, W.4
Li, C.5
Deng, C.X.6
-
36
-
-
0036595143
-
Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412
-
Weisberg E, Boulton C, Kelly LM, Manley P, Fabbro D, Meyer T et al. Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412. Cancer Cell 2002; 1: 433-443.
-
(2002)
Cancer Cell
, vol.1
, pp. 433-443
-
-
Weisberg, E.1
Boulton, C.2
Kelly, L.M.3
Manley, P.4
Fabbro, D.5
Meyer, T.6
-
37
-
-
0037108298
-
SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase
-
Yee KW, O'Farrell AM, Smolich BD, Cherrington JM, McMahon G, Wait CL et al. SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase. Blood 2002; 100: 2941-2949.
-
(2002)
Blood
, vol.100
, pp. 2941-2949
-
-
Yee, K.W.1
O'Farrell, A.M.2
Smolich, B.D.3
Cherrington, J.M.4
McMahon, G.5
Wait, C.L.6
-
38
-
-
0037441745
-
The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3
-
Spiekermann K, Dirschinger RJ, Schwab R, Bagrintseva K, Faber F, Buske C et al. The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3. Blood 2003; 101: 1494-1504.
-
(2003)
Blood
, vol.101
, pp. 1494-1504
-
-
Spiekermann, K.1
Dirschinger, R.J.2
Schwab, R.3
Bagrintseva, K.4
Faber, F.5
Buske, C.6
-
39
-
-
0036624916
-
A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo
-
Levis M, Allebach J, Tse KF, Zheng R, Baldwin BR, Smith BD et al. A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo. Blood 2002; 99: 3885-3891.
-
(2002)
Blood
, vol.99
, pp. 3885-3891
-
-
Levis, M.1
Allebach, J.2
Tse, K.F.3
Zheng, R.4
Baldwin, B.R.5
Smith, B.D.6
-
40
-
-
20444402664
-
FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model
-
Grundler R, Miething C, Thiede C, Peschel C, Duyster J. FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model. Blood 2005; 105: 4792-4799.
-
(2005)
Blood
, vol.105
, pp. 4792-4799
-
-
Grundler, R.1
Miething, C.2
Thiede, C.3
Peschel, C.4
Duyster, J.5
-
41
-
-
78751533109
-
NF-kappaB downregulates expression of the B-lymphoma marker CD10 through a miR-155/PU.1 pathway
-
Thompson RC, Herscovitch M, Zhao I, Ford TJ, Gilmore TD. NF-kappaB downregulates expression of the B-lymphoma marker CD10 through a miR-155/PU.1 pathway. J Biol Chem 2011; 286: 1675-1682.
-
(2011)
J Biol Chem
, vol.286
, pp. 1675-1682
-
-
Thompson, R.C.1
Herscovitch, M.2
Zhao, I.3
Ford, T.J.4
Gilmore, T.D.5
-
42
-
-
20544467182
-
Overexpression of Flt3 induces NF-kappaB pathway and increases the expression of IL-6
-
Takahashi S, Harigae H, Ishii KK, Inomata M, Fujiwara T, Yokoyama H et al. Overexpression of Flt3 induces NF-kappaB pathway and increases the expression of IL-6. Leuk Res 2005; 29: 893-899.
-
(2005)
Leuk Res
, vol.29
, pp. 893-899
-
-
Takahashi, S.1
Harigae, H.2
Ishii, K.K.3
Inomata, M.4
Fujiwara, T.5
Yokoyama, H.6
-
43
-
-
0035886024
-
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
-
Guzman ML, Neering SJ, Upchurch D, Grimes B, Howard DS, Rizzieri DA et al. Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 2001; 98: 2301-2307.
-
(2001)
Blood
, vol.98
, pp. 2301-2307
-
-
Guzman, M.L.1
Neering, S.J.2
Upchurch, D.3
Grimes, B.4
Howard, D.S.5
Rizzieri, D.A.6
-
44
-
-
10744224210
-
Expression of constitutively active nuclear-kappa B RelA transcription factor in blasts of acute myeloid leukemia
-
Bueso-Ramos CE, Rocha FC, Shishodia S, Medeiros LJ, Kantarjian HM, Vadhan-Raj S et al. Expression of constitutively active nuclear-kappa B RelA transcription factor in blasts of acute myeloid leukemia. Hum Pathol 2004; 35: 246-253.
-
(2004)
Hum Pathol
, vol.35
, pp. 246-253
-
-
Bueso-Ramos, C.E.1
Rocha, F.C.2
Shishodia, S.3
Medeiros, L.J.4
Kantarjian, H.M.5
Vadhan-Raj, S.6
-
45
-
-
17144387901
-
PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways
-
Grandage VL, Gale RE, Linch DC, Khwaja A. PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways. Leukemia 2005; 19: 586-594.
-
(2005)
Leukemia
, vol.19
, pp. 586-594
-
-
Grandage, V.L.1
Gale, R.E.2
Linch, D.C.3
Khwaja, A.4
-
46
-
-
27544450742
-
Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation
-
Brandts CH, Sargin B, Rode M, Biermann C, Lindtner B, Schwable J et al. Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation. Cancer Res 2005; 65: 9643-9650.
-
(2005)
Cancer Res
, vol.65
, pp. 9643-9650
-
-
Brandts, C.H.1
Sargin, B.2
Rode, M.3
Biermann, C.4
Lindtner, B.5
Schwable, J.6
-
47
-
-
49349094497
-
Flt3 receptor inhibition reduces constitutive NFkappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia
-
Grosjean-Raillard J, Ades L, Boehrer S, Tailler M, Fabre C, Braun T et al. Flt3 receptor inhibition reduces constitutive NFkappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia. Apoptosis 2008; 13: 1148-1161.
-
(2008)
Apoptosis
, vol.13
, pp. 1148-1161
-
-
Grosjean-Raillard, J.1
Ades, L.2
Boehrer, S.3
Tailler, M.4
Fabre, C.5
Braun, T.6
-
48
-
-
33847304124
-
CD34+ hematopoietic stem-progenitor cell microRNA expression and function: A circuit diagram of differentiation control
-
Georgantas III RW, Hildreth R, Morisot S, Alder J, Liu CG, Heimfeld S et al. CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control. Proc Natl Acad Sci USA 2007; 104: 2750-2755.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2750-2755
-
-
Georgantas, R.W.1
Hildreth, R.2
Morisot, S.3
Alder, J.4
Liu, C.G.5
Heimfeld, S.6
-
49
-
-
0031907329
-
Role of PU.1 in hematopoiesis
-
Fisher RC, Scott EW. Role of PU.1 in hematopoiesis. Stem Cells 1998; 16: 25-37.
-
(1998)
Stem Cells
, vol.16
, pp. 25-37
-
-
Fisher, R.C.1
Scott, E.W.2
-
50
-
-
0036771841
-
Increased IkappaB kinase activity is associated with activated NF-kappaB in acute myeloid blasts
-
Baumgartner B, Weber M, Quirling M, Fischer C, Page S, Adam M et al. Increased IkappaB kinase activity is associated with activated NF-kappaB in acute myeloid blasts. Leukemia 2002; 16: 2062-2071.
-
(2002)
Leukemia
, vol.16
, pp. 2062-2071
-
-
Baumgartner, B.1
Weber, M.2
Quirling, M.3
Fischer, C.4
Page, S.5
Adam, M.6
-
51
-
-
84879398642
-
STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma
-
Kopp KL, Ralfkiaer U, Gjerdrum LM, Helvad R, Pedersen IH, Litman T et al. STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma. Cell Cycle 2013; 12: 1939-1947.
-
(2013)
Cell Cycle
, vol.12
, pp. 1939-1947
-
-
Kopp, K.L.1
Ralfkiaer, U.2
Gjerdrum, L.M.3
Helvad, R.4
Pedersen, I.H.5
Litman, T.6
-
52
-
-
0037155133
-
Cytokine receptor common beta subunit-mediated STAT5 activation confers NF-kappa B activation in murine proB cell line Ba/F3 cells
-
Nakamura T, Ouchida R, Kodama T, Kawashima T, Makino Y, Yoshikawa N et al. Cytokine receptor common beta subunit-mediated STAT5 activation confers NF-kappa B activation in murine proB cell line Ba/F3 cells. J Biol Chem 2002; 277: 6254-6265.
-
(2002)
J Biol Chem
, vol.277
, pp. 6254-6265
-
-
Nakamura, T.1
Ouchida, R.2
Kodama, T.3
Kawashima, T.4
Makino, Y.5
Yoshikawa, N.6
-
53
-
-
70350087559
-
STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells
-
Nagy ZS, LeBaron MJ, Ross JA, Mitra A, Rui H, Kirken RA. STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells. Mol Cancer 2009; 8: 67.
-
(2009)
Mol Cancer
, vol.8
, pp. 67
-
-
Nagy, Z.S.1
LeBaron, M.J.2
Ross, J.A.3
Mitra, A.4
Rui, H.5
Kirken, R.A.6
-
54
-
-
67650227725
-
MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by downregulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN)
-
Martinez-Nunez RT, Louafi F, Friedmann PS, Sanchez-Elsner T. MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by downregulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN). J Biol Chem 2009; 284: 16334-16342.
-
(2009)
J Biol Chem
, vol.284
, pp. 16334-16342
-
-
Martinez-Nunez, R.T.1
Louafi, F.2
Friedmann, P.S.3
Sanchez-Elsner, T.4
-
55
-
-
37049002638
-
microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells
-
Vigorito E, Perks KL, Abreu-Goodger C, Bunting S, Xiang Z, Kohlhaas S et al. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity 2007; 27: 847-859.
-
(2007)
Immunity
, vol.27
, pp. 847-859
-
-
Vigorito, E.1
Perks, K.L.2
Abreu-Goodger, C.3
Bunting, S.4
Xiang, Z.5
Kohlhaas, S.6
-
56
-
-
31944450531
-
Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia
-
Metcalf D, Dakic A, Mifsud S, Di Rago L, Wu L, Nutt S. Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia. Proc Natl Acad Sci USA 2006; 103: 1486-1491.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1486-1491
-
-
Metcalf, D.1
Dakic, A.2
Mifsud, S.3
Di Rago, L.4
Wu, L.5
Nutt, S.6
-
57
-
-
2642519463
-
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1
-
Rosenbauer F, Wagner K, Kutok JL, Iwasaki H, Le Beau MM, Okuno Y et al. Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1. Nat Genet 2004; 36: 624-630.
-
(2004)
Nat Genet
, vol.36
, pp. 624-630
-
-
Rosenbauer, F.1
Wagner, K.2
Kutok, J.L.3
Iwasaki, H.4
Le Beau, M.M.5
Okuno, Y.6
-
58
-
-
0028021829
-
Inhibition of hematopoiesis by competitive binding of transcription factor PU.1
-
Voso MT, Burn TC, Wulf G, Lim B, Leone G, Tenen DG. Inhibition of hematopoiesis by competitive binding of transcription factor PU.1. Proc Natl Acad Sci USA 1994; 91: 7932-7936.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7932-7936
-
-
Voso, M.T.1
Burn, T.C.2
Wulf, G.3
Lim, B.4
Leone, G.5
Tenen, D.G.6
-
59
-
-
84862993281
-
Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma
-
Babar IA, Cheng CJ, Booth CJ, Liang X, Weidhaas JB, Saltzman WM et al. Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma. Proc Natl Acad Sci USA 2012; 109: E1695-E1704.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. E1695-E1704
-
-
Babar, I.A.1
Cheng, C.J.2
Booth, C.J.3
Liang, X.4
Weidhaas, J.B.5
Saltzman, W.M.6
-
60
-
-
70450267416
-
PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL
-
Ueno S, Tatetsu H, Hata H, Iino T, Niiro H, Akashi K et al. PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL. Oncogene 2009; 28: 4116-4125.
-
(2009)
Oncogene
, vol.28
, pp. 4116-4125
-
-
Ueno, S.1
Tatetsu, H.2
Hata, H.3
Iino, T.4
Niiro, H.5
Akashi, K.6
-
61
-
-
84865403336
-
LNA-mediated anti-miR-155 silencing in low-grade B-cell lymphomas
-
Zhang Y, Roccaro AM, Rombaoa C, Flores L, Obad S, Fernandes SM et al. LNA-mediated anti-miR-155 silencing in low-grade B-cell lymphomas. Blood 2012; 120: 1678-1686.
-
(2012)
Blood
, vol.120
, pp. 1678-1686
-
-
Zhang, Y.1
Roccaro, A.M.2
Rombaoa, C.3
Flores, L.4
Obad, S.5
Fernandes, S.M.6
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