Attenuation of miR-126 activity expands HSC in vivo without exhaustion

Cell Stem Cell

Volumn 11, Issue 6, 2012, Pages 799-811

  Lechman, Eric R ^a,b   Gentner, Bernhard ^c,d   Van Galen, Peter ^a,b   Giustacchini, Alice ^c,d   Saini, Massimo ^c,d   Boccalatte, Francesco E ^c,d   Hiramatsu, Hidefumi ^f   Restuccia, Umberto ^e   Bachi, Angela ^e   Voisin, Veronique ^b   Bader, Gary D ^b   Dick, John E ^a,b   Naldini, Luigi ^c,d  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^d VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^e SAN RAFFAELE HOSPITAL   (Italy)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; LENTIVIRUS VECTOR; MICRORNA 126; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL CYCLE PROGRESSION; CELL EXPANSION; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; GENE POOL; GENE SILENCING; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CELL PROLIFERATION; GENE KNOCKDOWN TECHNIQUES; GLYCOGEN SYNTHASE KINASE 3; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; MICRORNAS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 84870894496     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2012.09.001     Document Type: Article

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