An allelic series of miR-171/492-mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron

Nature Genetics

Volumn 47, Issue 7, 2015, Pages 766-775

  Han, Yoon Chi ^a,b   Vidigal, Joana A ^a   Mu, Ping ^a,c   Yao, Evelyn ^a   Singh, Irtisha ^a   González, Alvaro J ^a,c   Concepcion, Carla P ^a   Bonetti, Ciro ^a   Ogrodowski, Paul ^a   Carver, Brett ^a   Selleri, Licia ^d   Betel, Doron ^d   Leslie, Christina ^a   Ventura, Andrea ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b PFIZER INC   (United States)

^c Weill Cornell Medical Center   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 17 92; UNCLASSIFIED DRUG; MIRN17-92 MICRORNA, MOUSE;

ALLELE; ARTICLE; BIOLOGICAL FUNCTIONS; CARCINOGENESIS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEART DEVELOPMENT; HOMOLOGOUS RECOMBINATION; IN VIVO STUDY; LUNG HYPOPLASIA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION; RNA SEQUENCE; SEQUENCE HOMOLOGY; SPECIALIZATION; VERTEBRATE; 129 MOUSE; ABNORMALITIES; ANIMAL; APOPTOSIS; B LYMPHOCYTE; C57BL MOUSE; CELL CULTURE; EYELID; GENE FREQUENCY; GENETICS; GENOME-WIDE ASSOCIATION STUDY; INTELLECTUAL IMPAIRMENT; LETHAL GENE; LIMB MALFORMATION; MALE; MICROCEPHALY; MULTIGENE FAMILY; MUTATION; PHYSIOLOGY; TRACHEOESOPHAGEAL FISTULA; TRANSGENIC MOUSE;

MUS; VERTEBRATA;

ANIMALS; APOPTOSIS; B-LYMPHOCYTES; CARCINOGENESIS; CELLS, CULTURED; EYELIDS; GENE FREQUENCY; GENES, LETHAL; GENOME-WIDE ASSOCIATION STUDY; INTELLECTUAL DISABILITY; LIMB DEFORMITIES, CONGENITAL; MALE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROCEPHALY; MICRORNAS; MULTIGENE FAMILY; MUTATION; TRACHEOESOPHAGEAL FISTULA;

EID: 84933277411     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3321     Document Type: Article

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