MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis

Journal of Clinical Investigation

Volumn 125, Issue 3, 2015, Pages 1069-1080

  Murugaiyan, Gopal ^a   Da Cunha, Andre Pires ^a   Ajay, Amrendra K ^a   Joller, Nicole ^a,b   Garo, Lucien P ^a   Kumaradevan, Sowmiya ^a   Yosef, Nir ^c   Vaidya, Vishal S ^a   Weiner, Howard L ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR6; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 22; MICRORNA 21; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; SMALL NUCLEAR RNA; TRANSFORMING GROWTH FACTOR BETA; MICRORNA; MIRN21 MICRORNA, MOUSE; SMAD7 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; TH2 CELL; ANIMAL; BINDING SITE; C57BL MOUSE; CELL CULTURE; FEMALE; GENE EXPRESSION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHYSIOLOGY; RNA INTERFERENCE;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL DIFFERENTIATION; CELLS, CULTURED; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE EXPRESSION; INTERLEUKIN-17; MICE, INBRED C57BL; MICRORNAS; RNA INTERFERENCE; SMAD7 PROTEIN; TH17 CELLS;

EID: 84924028501     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI74347     Document Type: Article

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