IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells

Journal of Immunology

Volumn 190, Issue 4, 2013, Pages 1827-1836

  Ding, B Belinda ^a   Bi, Enguang ^a   Chen, Hongshan ^a   Yu, J Jessica ^a   Ye, B Hilda ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; CD40 LIGAND; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 4; JANUS KINASE; JANUS KINASE 3; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN BCL 6; SMALL INTERFERING RNA; STAT3 PROTEIN; TRANSCRIPTION FACTOR PAX5;

ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CD8+ T LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; DNA BASE COMPOSITION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GERMINAL CENTER; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MOLECULAR DYNAMICS; PHENOTYPE; PLASMA CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TONSIL CELL; WESTERN BLOTTING;

ADJUVANTS, IMMUNOLOGIC; B-LYMPHOCYTE SUBSETS; CD40 LIGAND; CELL DIFFERENTIATION; CELL LINE, TUMOR; HUMANS; INTERLEUKINS; JANUS KINASES; MOLECULAR SEQUENCE DATA; ORGAN CULTURE TECHNIQUES; PALATINE TONSIL; PLASMA CELLS; REPRESSOR PROTEINS; STAT3 TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84873536866     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201678     Document Type: Article

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