Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a

Journal of Experimental Medicine

Volumn 212, Issue 4, 2015, Pages 569-580

  Zhou, Yan ^a   Li, Yue Sheng ^a   Bandi, Srinivasa Rao ^a   Tang, Lingjuan ^a   Shinton, Susan A ^a   Hayakawa, Kyoko ^a   Hardy, Richard R ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ARID3A; UNCLASSIFIED DRUG; ARID3A PROTEIN, MOUSE; DNA BINDING PROTEIN; LIN28B PROTEIN, MOUSE; MICRORNA; MIRNLET7 MICRORNA, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FETUS; FETUS DEVELOPMENT; GENE EXPRESSION; LYMPHOPOIESIS; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROGENY; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; CYTOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; GENETICS; IMMUNOLOGY; SCID MOUSE;

ANIMALS; B-LYMPHOCYTE SUBSETS; DNA-BINDING PROTEINS; FEMALE; FETUS; GENE EXPRESSION REGULATION; LYMPHOPOIESIS; MICE; MICE, INBRED BALB C; MICE, SCID; MICRORNAS; PRECURSOR CELLS, B-LYMPHOID; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC;

EID: 84928239791     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20141510     Document Type: Article

References (34)

1. Carmack, C.E., S.A. Shinton, K. Hayakawa, and R.R. Hardy. 1990. Rearrangement and selection of VH11 in the Ly-1 B cell lineage. J. Exp. Med. 172:371-374. http://dx.doi.org/10.1084/jem.172.1.371
2. Dickins, R.A., M.T. Hemann, J.T. Zilfou, D.R. Simpson, I. Ibarra, G.J. Hannon, and S.W. Lowe. 2005. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat. Genet. 37:1289-1295. http://dx.doi.org//10.1038/ng1651
3. Dickins, R.A., K. McJunkin, E. Hernando, P.K. Premsrirut, V. Krizhanovsky, D.J. Burgess, S.Y. Kim, C. Cordon-Cardo, L. Zender, G.J. Hannon, and S.W. Lowe. 2007. Tissue-specific and reversible RNA interference in transgenic mice. Nat. Genet. 39:914-921. http://dx.doi.org/10.1038/ng2045
4. Förster, I., H. Gu, and K. Rajewsky. 1988. Germline antibody V regions as determinants of clonal persistence and malignant growth in the B cell compartment. EMBO J. 7:3693-3703.
5. Goebel, P., A. Montalbano, N. Ayers, E. Kompfner, L. Dickinson, C.F. Webb, and A.J. Feeney. 2002. High frequency of matrix attachment regions and cut-like protein x/CCAAT-displacement protein and B cell regulator of IgH transcription binding sites flanking Ig V region genes. J. Immunol. 169:2477-2487. http://dx.doi.org/10.4049/jimmunol.169.5.2477
6. Goodnow, C.C. 2007. Multistep pathogenesis of autoimmune disease. Cell. 130:25-35. http://dx.doi.org/10.1016/j.cell.2007.06.033
7. Groudine, M., T. Kohwi-Shigematsu, R. Gelinas, G. Stamatoyannopoulos, and T. Papayannopoulou. 1983. Human fetal to adult hemoglobin switching: changes in chromatin structure of the beta-globin gene locus. Proc. Natl. Acad. Sci. USA. 80:7551-7555. http://dx.doi.org/10.1073/pnas.80.24.7551
8. Hardy, R.R., and K. Hayakawa. 1991. A developmental switch in B lymphopoiesis. Proc. Natl. Acad. Sci. USA. 88:11550-11554. http://dx.doi.org/10.1073/pnas.88.24.11550
9. Hardy, R.R., and K. Hayakawa. 2001. B cell development pathways. Annu. Rev. Immunol. 19:595-621. http://dx.doi.org/10.1146/annurev.immunol.19.1.595
10. Hayakawa, K., R.R. Hardy, D.R. Parks, and L.A. Herzenberg. 1983. The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice. J. Exp. Med. 157:202-218. http://dx.doi.org/10.1084/jem.157.1.202
11. Hayakawa, K., R.R. Hardy, M. Honda, L.A. Herzenberg, A.D. Steinberg, and L.A. Herzenberg. 1984. Ly-1 B cells: functionally distinct lymphocytes that secrete IgM autoantibodies. Proc. Natl. Acad. Sci. USA. 81:2494-2498. http://dx.doi.org/10.1073/pnas.81.8.2494
12. Hayakawa, K., R.R. Hardy, L.A. Herzenberg, and L.A. Herzenberg. 1985. Progenitors for Ly-1 B cells are distinct from progenitors for other B cells. J. Exp. Med. 161:1554-1568. http://dx.doi.org/10.1084/jem.161.6.1554
13. Hayakawa, K., M. Asano, S.A. Shinton, M. Gui, D. Allman, C.L. Stewart, J. Silver, and R.R. Hardy. 1999. Positive selection of natural autoreactive B cells. Science. 285:113-116. http://dx.doi.org/10.1126/science.285.5424.113
14. Herrscher, R.F., M.H. Kaplan, D.L. Lelsz, C. Das, R. Scheuermann, and P.W. Tucker. 1995. The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family. Genes Dev. 9:3067-3082. http://dx.doi.org/10.1101/gad.9.24.3067
15. Inaoki, M., S. Sato, B.C. Weintraub, C.C. Goodnow, and T.F. Tedder. 1997. CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. J. Exp. Med. 186:1923-1931. http://dx.doi.org/10.1084/jem.186.11.1923
16. Khan, W.N., F.W. Alt, R.M. Gerstein, B.A. Malynn, I. Larsson, G. Rathbun, L. Davidson, S. Müller, A.B. Kantor, L.A. Herzenberg, et al. 1995. Defective B cell development and function in Btk-deficient mice. Immunity. 3:283-299. http://dx.doi.org/10.1016/1074-7613(95)90114-0
17. Kim, D., and P.W. Tucker. 2006. A regulated nucleocytoplasmic shuttle contributes to Bright's function as a transcriptional activator of immunoglobulin genes. Mol. Cell. Biol. 26:2187-2201. http://dx.doi.org/10.1128/MCB.26.6.2187-2201.2006
18. Li, Y.S., K. Hayakawa, and R.R. Hardy. 1993. The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver. J. Exp. Med. 178:951-960. http://dx.doi.org/10.1084/jem.178.3.951
19. Mayr, F., A. Schütz, N. Döge, and U. Heinemann. 2012. The Lin28 cold-shock domain remodels pre-let-7 microRNA. Nucleic Acids Res. 40:7492-7506. http://dx.doi.org/10.1093/nar/gks355
20. Nemazee, D. 2006. Receptor editing in lymphocyte development and central tolerance. Nat. Rev. Immunol. 6:728-740. http://dx.doi.org/10.1038/nri1939
21. Nixon, J.C., S. Ferrell, C. Miner, A.L. Oldham, U. Hochgeschwender, and C.F. Webb. 2008. Transgenic mice expressing dominant-negative bright exhibit defects in B1 B cells. J. Immunol. 181:6913-6922. http://dx.doi.org/10.4049/jimmunol.181.10.6913
22. Oldham, A.L., C.A. Miner, H.C. Wang, and C.F. Webb. 2011. The transcription factor Bright plays a role in marginal zone B lymphocyte development and autoantibody production. Mol. Immunol. 49:367-379. http://dx.doi.org/10.1016/j.molimm.2011.09.008
23. Pennell, C.A., T.J. Mercolino, T.A. Grdina, L.W. Arnold, G. Haughton, and S.H. Clarke. 1989. Biased immunoglobulin variable region gene expression by Ly-1 B cells due to clonal selection. Eur. J. Immunol. 19:1289-1295. http://dx.doi.org/10.1002/eji.1830190721
24. Puissegur, M.P., R. Eichner, C. Quelen, E. Coyaud, B. Mari, K. Lebrigand, C. Broccardo, F. Nguyen-Khac, M. Bousquet, and P. Brousset. 2012. B-cell regulator of immunoglobulin heavy-chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells. Leukemia. 26:2224-2232. http://dx.doi.org/10.1038/leu.2012.95
25. Rajaiya, J., M. Hatfield, J.C. Nixon, D.J. Rawlings, and C.F. Webb. 2005. Bruton's tyrosine kinase regulates immunoglobulin promoter activation in association with the transcription factor Bright. Mol. Cell. Biol. 25:2073-2084. http://dx.doi.org/10.1128/MCB.25.6.2073-2084.2005
26. Rawlings, D.J., D.C. Saffran, S. Tsukada, D.A. Largaespada, J.C. Grimaldi, L. Cohen, R.N. Mohr, J.F. Bazan, M. Howard, N.G. Copeland, et al. 1993. Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science. 261:358-361. http://dx.doi.org/10.1126/science.8332901
27. Rumfelt, L.L., Y. Zhou, B.M. Rowley, S.A. Shinton, and R.R. Hardy. 2006. Lineage specification and plasticity in CD19-early B cell precursors. J. Exp. Med. 203:675-687. http://dx.doi.org/10.1084/jem.20052444
28. Schmidt, C., D. Kim, G.C. Ippolito, H.R. Naqvi, L. Probst, S. Mathur, G. Rosas-Acosta, V.G. Wilson, A.L. Oldham, M. Poenie, et al. 2009. Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright. EMBO J. 28:711-724. http://dx.doi.org/10.1038/emboj.2009.20
29. Suzuki, H., Y. Terauchi, M. Fujiwara, S. Aizawa, Y. Yazaki, T. Kadowaki, and S. Koyasu. 1999. Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase. Science. 283:390-392. http://dx.doi.org/10.1126/science.283.5400.390
30. Tarakhovsky, A., M. Turner, S. Schaal, P.J. Mee, L.P. Duddy, K. Rajewsky, and V.L. Tybulewicz. 1995. Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav. Nature. 374:467-470. http://dx.doi.org/10.1038/374467a0
31. Webb, C.F., E.A. Smith, K.L. Medina, K.L. Buchanan, G. Smithson, and S. Dou. 1998. Expression of bright at two distinct stages of B lymphocyte development. J. Immunol. 160:4747-4754.
32. Webb, C.F., Y. Yamashita, N. Ayers, S. Evetts, Y. Paulin, M.E. Conley, and E.A. Smith. 2000. The transcription factor Bright associates with Bruton's tyrosine kinase, the defective protein in immunodeficiency disease. J. Immunol. 165:6956-6965. http://dx.doi.org/10.4049/jimmunol.165.12.6956
33. Webb, C.F., J. Bryant, M. Popowski, L. Allred, D. Kim, J. Harriss, C. Schmidt, C.A. Miner, K. Rose, H.L. Cheng, et al. 2011. The ARID family transcription factor bright is required for both hematopoietic stem cell and B lineage development. Mol. Cell. Biol. 31:1041-1053. http://dx.doi.org/10.1128/MCB.01448-10
34. Yuan, J., C.K. Nguyen, X. Liu, C. Kanellopoulou, and S.A. Muljo. 2012. Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis. Science. 335:1195-1200. http://dx.doi.org/10.1126/science.1216557