-
1
-
-
0034879612
-
Identification of very early lymphoid precursors in bone marrow and their regulation by estrogen
-
Medina, K. L. et al. Identification of very early lymphoid precursors in bone marrow and their regulation by estrogen. Nature Immunol. 2, 718-724 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 718-724
-
-
Medina, K.L.1
-
2
-
-
0036669273
-
Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow
-
Igarashi, H., Gregory, S. C., Yokota, T., Sakaguchi, N. & Kincade, P. W. Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity 17, 117-130 (2002).
-
(2002)
Immunity
, vol.17
, pp. 117-130
-
-
Igarashi, H.1
Gregory, S.C.2
Yokota, T.3
Sakaguchi, N.4
Kincade, P.W.5
-
3
-
-
0037320932
-
Thymopoiesis independent of common lymphoid progenitors
-
Allman, D. et al. Thymopoiesis independent of common lymphoid progenitors. Nature Immunol. 4, 168-174 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 168-174
-
-
Allman, D.1
-
4
-
-
0042383366
-
Efficient thymic immigration of B220-lymphoid-restricted bone marrow cells with T precursor potential
-
Martin, C. H. et al. Efficient thymic immigration of B220-lymphoid- restricted bone marrow cells with T precursor potential. Nature Immunol. 4, 866-873 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 866-873
-
-
Martin, C.H.1
-
5
-
-
0029886467
-
Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development
-
Loffert, D., Ehlich, A., Muller, W. & Rajewsky, K. Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development. Immunity 4, 133-144 (1996).
-
(1996)
Immunity
, vol.4
, pp. 133-144
-
-
Loffert, D.1
Ehlich, A.2
Muller, W.3
Rajewsky, K.4
-
6
-
-
0037097681
-
L VpreB1/VpreB2/λ5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus
-
Shimizu, T., Mundt, C., Licence, S., Melchers, F. & Martensson, I. L VpreB1/VpreB2/λ5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus. J. Immunol. 168, 286-6293 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 286-6293
-
-
Shimizu, T.1
Mundt, C.2
Licence, S.3
Melchers, F.4
Martensson, I.5
-
7
-
-
0034608364
-
Revising B cell receptors
-
Nemazee, D. & Weigert, M. Revising B cell receptors. J. Exp. Med 191, 1813-1817 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1813-1817
-
-
Nemazee, D.1
Weigert, M.2
-
8
-
-
0033526816
-
B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals
-
Loder, F. et al. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J. Exp. Med. 190, 75-89 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 75-89
-
-
Loder, F.1
-
9
-
-
0035230221
-
Bipotential B-macrophage progenitors are present in adult bone marrow
-
Montecino-Rodriguez, E., Leathers, H. & Dorshkind, K. Bipotential B-macrophage progenitors are present in adult bone marrow. Nature Immunol. 2, 83-88 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 83-88
-
-
Montecino-Rodriguez, E.1
Leathers, H.2
Dorshkind, K.3
-
10
-
-
0242549003
-
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
-
McKercher, S. R. et al. Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J. 15, 5647-5658 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 5647-5658
-
-
McKercher, S.R.1
-
11
-
-
0028136726
-
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
-
Scott, E. W., Simon, M. C., Anastasi, J. & Singh, H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265, 1573-1577 (1994). This was the first study to show that PU.1 is required for the earliest stages of lymphocyte development
-
(1994)
Science
, vol.265
, pp. 1573-1577
-
-
Scott, E.W.1
Simon, M.C.2
Anastasi, J.3
Singh, H.4
-
12
-
-
0030611964
-
PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors
-
Scott, E. W. et al. PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity 6, 437-447 (1997).
-
(1997)
Immunity
, vol.6
, pp. 437-447
-
-
Scott, E.W.1
-
13
-
-
0032479989
-
PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors
-
DeKoter, R. P., Walsh, J. C. & Singh, H. PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors. EMBO J. 17, 4456-4468 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 4456-4468
-
-
DeKoter, R.P.1
Walsh, J.C.2
Singh, H.3
-
14
-
-
0036199657
-
PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors
-
DeKoter, R. P., Lee, H. J. & Singh, H. PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity 16, 297-309 (2002).
-
(2002)
Immunity
, vol.16
, pp. 297-309
-
-
DeKoter, R.P.1
Lee, H.J.2
Singh, H.3
-
15
-
-
0346103726
-
Analysis of gene expression and Ig transcription in PU.1/Spi-B-deficient progenitor B cell lines
-
Schweitzer, B. L. & DeKoter, R. P. Analysis of gene expression and Ig transcription in PU.1/Spi-B-deficient progenitor B cell lines. J. Immunol. 172, 144-154 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 144-154
-
-
Schweitzer, B.L.1
DeKoter, R.P.2
-
16
-
-
0030683640
-
Defective B cell receptor-mediated responses in mice lacking the EtS protein, Spi-B
-
Su, G. H. et al. Defective B cell receptor-mediated responses in mice lacking the EtS protein, Spi-B. EMBO J. 16, 7118-7129 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 7118-7129
-
-
Su, G.H.1
-
17
-
-
0036566050
-
Spi-B can functionally replace PU.1 in myeloid but not lymphoid development
-
Dahl, R., Ramirez-Bergeron, D. L., Rao, S. & Simon, M. C. Spi-B can functionally replace PU.1 in myeloid but not lymphoid development. EMBO J. 21, 2220-2230 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 2220-2230
-
-
Dahl, R.1
Ramirez-Bergeron, D.L.2
Rao, S.3
Simon, M.C.4
-
18
-
-
0034717335
-
Regulation of B lymphocyte and macrophage development by graded expression of PU.1
-
DeKoter, R. P. & Singh, H. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288, 1439-1441 (2000).
-
(2000)
Science
, vol.288
, pp. 1439-1441
-
-
DeKoter, R.P.1
Singh, H.2
-
19
-
-
2642519463
-
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1
-
Rosenbauer, F. et al. Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1. Nature Genet. 36, 624-630 (2004).
-
(2004)
Nature Genet.
, vol.36
, pp. 624-630
-
-
Rosenbauer, F.1
-
20
-
-
0030933151
-
The role of the Ikaros gene in lymphocyte development and homeostasis
-
Georgopoulos, K., Winandy S. & Avitahl, N. The role of the Ikaros gene in lymphocyte development and homeostasis. Annu. Rev. Immunol. 15, 155-176 (1997).
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 155-176
-
-
Georgopoulos, K.1
Winandy, S.2
Avitahl, N.3
-
21
-
-
0032560018
-
Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors
-
Kelley, C. M. et al. Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr. Biol. 8, 508-515 (1998).
-
(1998)
Curr. Biol.
, vol.8
, pp. 508-515
-
-
Kelley, C.M.1
-
22
-
-
0030972497
-
Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation
-
Morgan, B. et al. Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation. EMBO J. 16, 2004-2013 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 2004-2013
-
-
Morgan, B.1
-
23
-
-
0033152491
-
Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes
-
Koipally, J., Renold, A., Kim, J. & Georgopoulos, K. Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes. EMBO J. 18, 3090-3100 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 3090-3100
-
-
Koipally, J.1
Renold, A.2
Kim, J.3
Georgopoulos, K.4
-
24
-
-
0033103374
-
Ikaros DMA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes
-
Kim, J. et al. Ikaros DMA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 10, 345-355 (1999).
-
(1999)
Immunity
, vol.10
, pp. 345-355
-
-
Kim, J.1
-
25
-
-
0028001362
-
The Ikaros gene is required for the development of all lymphoid lineages
-
Georgopoulos, K. et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell 79, 143-156 (1994). This work showed the crucial role of Ikaros for the generation of all lymphocytic lineages.
-
(1994)
Cell
, vol.79
, pp. 143-156
-
-
Georgopoulos, K.1
-
26
-
-
0030498975
-
Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
-
Wang, J. H. et al. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 5, 537-549 (1996).
-
(1996)
Immunity
, vol.5
, pp. 537-549
-
-
Wang, J.H.1
-
27
-
-
0033231420
-
Defects in hemopoietic stem cell activity in Ikaros mutant mice
-
Nichogiannopoulou, A., Trevisan, M., Neben, S., Friedrich, C. & Georgopoulos, K. Defects in hemopoietic stem cell activity in Ikaros mutant mice. J. Exp. Med. 190, 1201-1214 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1201-1214
-
-
Nichogiannopoulou, A.1
Trevisan, M.2
Neben, S.3
Friedrich, C.4
Georgopoulos, K.5
-
28
-
-
0036201410
-
Ikaros is critical for B cell differentiation and function
-
Kirstetter, P., Thomas, M., Dierich, A., Kastner, P. & Chan, S. Ikaros is critical for B cell differentiation and function. Eur. J. Immunol. 32, 720-730 (2002).
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 720-730
-
-
Kirstetter, P.1
Thomas, M.2
Dierich, A.3
Kastner, P.4
Chan, S.5
-
29
-
-
0038106526
-
Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor
-
Papathanasiou, P. et al. Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity 19, 131-144 (2003). This Interesting paper showed that an Ikaros gene with a point mutation In the region encoding the DNA-binding domain has a stronger phenotype in mice than a null mutant, presumably because it inactivates several Ikaros-containing complexes.
-
(2003)
Immunity
, vol.19
, pp. 131-144
-
-
Papathanasiou, P.1
-
30
-
-
0035878121
-
+ thymocytes by Ikaros proteins in direct competition with an EtS activator
-
+ thymocytes by Ikaros proteins in direct competition with an EtS activator. Genes Dev. 15, 1817-1832 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 1817-1832
-
-
Trinh, L.A.1
-
31
-
-
0035355509
-
Binding of Ikaros to the λ5 promoter silences transcription through a mechanism that does not require heterochromatin formation
-
Sabbattini, P. et al. Binding of Ikaros to the λ5 promoter silences transcription through a mechanism that does not require heterochromatin formation. EMBO J. 20, 2812-2822 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 2812-2822
-
-
Sabbattini, P.1
-
32
-
-
0036886895
-
The CD8α gene locus is regulated by the Ikaros family of proteins
-
Harker, N. et al. The CD8α gene locus is regulated by the Ikaros family of proteins, Mol. Cell 10, 1403-1415 (2002).
-
(2002)
Mol. Cell
, vol.10
, pp. 1403-1415
-
-
Harker, N.1
-
33
-
-
0027992622
-
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
-
Bain, G. et al. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell 79, 885-892 (1994). This paper, together with references 37 and 41, was the first to identify the crucial role of E2A proteins in the earliest stages of B-cell development.
-
(1994)
Cell
, vol.79
, pp. 885-892
-
-
Bain, G.1
-
34
-
-
0033946934
-
E2A proteins: Essential regulators at multiple stages of B-cell development
-
Kee, B. L., Quong, M. W. & Murre, C. E2A proteins: essential regulators at multiple stages of B-cell development. Immunol. Rev. 175, 138-149 (2000).
-
(2000)
Immunol. Rev.
, vol.175
, pp. 138-149
-
-
Kee, B.L.1
Quong, M.W.2
Murre, C.3
-
35
-
-
0030752361
-
E2A deficiency leads to abnormalities in αβ T-cell development and to rapid development of T-cell lymphomas
-
Bain, G. et al. E2A deficiency leads to abnormalities in αβ T-cell development and to rapid development of T-cell lymphomas. Mol. Cell. Biol. 17, 4782-4791 (1997).
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4782-4791
-
-
Bain, G.1
-
36
-
-
1142285361
-
Regulation of E2A gene expression in B-lymphocyte development
-
Zhuang, Y., Jackson, A., Pan, L., Shen, K. & Dai, M. Regulation of E2A gene expression in B-lymphocyte development. Mol. Immunol. 40, 1165-1177 (2004).
-
(2004)
Mol. Immunol.
, vol.40
, pp. 1165-1177
-
-
Zhuang, Y.1
Jackson, A.2
Pan, L.3
Shen, K.4
Dai, M.5
-
37
-
-
0028148938
-
The helix-loop-helix gene F24 is required for B cell formation
-
Zhuang, Y., Soriano, P. & Weintraub, H. The helix-loop-helix gene F24 is required for B cell formation. Cell 79, 875-884 (1994).
-
(1994)
Cell
, vol.79
, pp. 875-884
-
-
Zhuang, Y.1
Soriano, P.2
Weintraub, H.3
-
38
-
-
0033166656
-
A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex
-
Massari, M. E. et al. A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex. Mol. Cell 4, 63-73 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 63-73
-
-
Massari, M.E.1
-
39
-
-
0029896451
-
B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB
-
Zhuang, Y., Cheng, P. & Weintraub, H. B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB. Mol. Cell. Biol. 16, 2898-2905 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2898-2905
-
-
Zhuang, Y.1
Cheng, P.2
Weintraub, H.3
-
40
-
-
0031867289
-
Functional replacement of the mouse E2A gene with a human HEB cDNA
-
Zhuang, Y., Barndt, R. J., Pan, L., Kelley, R. & Dai, M. Functional replacement of the mouse E2A gene with a human HEB cDNA. Mol. Cell. Biol. 18, 3340-3349 (1998).
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3340-3349
-
-
Zhuang, Y.1
Barndt, R.J.2
Pan, L.3
Kelley, R.4
Dai, M.5
-
41
-
-
0028088556
-
Constitutive expression of the Id1 gene impairs mouse B cell development
-
Sun, X. H. Constitutive expression of the Id1 gene impairs mouse B cell development. Cell 79, 893-900 (1994).
-
(1994)
Cell
, vol.79
, pp. 893-900
-
-
Sun, X.H.1
-
42
-
-
0029076534
-
EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains
-
Hagman, J., Gutch, M. J., Lin, H. & Grosschedl, R. EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains. EMBO J. 14, 2907-2916 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 2907-2916
-
-
Hagman, J.1
Gutch, M.J.2
Lin, H.3
Grosschedl, R.4
-
43
-
-
0029045161
-
Failure of B-cell differentiation in mice lacking the transcription factor EBF
-
Lin, H. & Grosschedl, R. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature 376, 263-267 (1995). The was the first report to identify the crucial role of EBF at the pro-B-cell stage of development.
-
(1995)
Nature
, vol.376
, pp. 263-267
-
-
Lin, H.1
Grosschedl, R.2
-
44
-
-
3042693975
-
Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A
-
Seet, C. S., Brumbaugh, R. L. & Kee, B. L. Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A. J. Exp. Med. 199, 1689-1700 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1689-1700
-
-
Seet, C.S.1
Brumbaugh, R.L.2
Kee, B.L.3
-
45
-
-
0036644320
-
Cloning and characterization of a promoter flanking the early B cell factor (EBF) gene indicates roles for E-proteins and autoregulation in the control of EBF expression
-
Smith, E. M., Gisler, R. & Sigvardsson, M. Cloning and characterization of a promoter flanking the early B cell factor (EBF) gene indicates roles for E-proteins and autoregulation in the control of EBF expression. J. Immunol. 169, 261-270 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 261-270
-
-
Smith, E.M.1
Gisler, R.2
Sigvardsson, M.3
-
46
-
-
0033166301
-
Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A
-
O'Riordan, M. & Grosschedl, R. Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A. Immunity 11, 21-31 (1999).
-
(1999)
Immunity
, vol.11
, pp. 21-31
-
-
O'Riordan, M.1
Grosschedl, R.2
-
47
-
-
0030790713
-
EBF and 47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes
-
Sigvardsson, M., O'Riordan, M. & Grosschedl, R. EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes. Immunity 7, 25-36 (1997).
-
(1997)
Immunity
, vol.7
, pp. 25-36
-
-
Sigvardsson, M.1
O'Riordan, M.2
Grosschedl, R.3
-
48
-
-
0033871151
-
E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells
-
Romanow, W. J. et al. E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells. Mol. Cell 5, 343-353 (2000).
-
(2000)
Mol Cell
, vol.5
, pp. 343-353
-
-
Romanow, W.J.1
-
49
-
-
5044249424
-
Assembling a gene regulatory network for specification of the B cell fate
-
Medina, K. L. et al. Assembling a gene regulatory network for specification of the B cell fate. Dev. Cell 7, 607-617 (2004).
-
(2004)
Dev. Cell
, vol.7
, pp. 607-617
-
-
Medina, K.L.1
-
50
-
-
18744388827
-
Early B-cell factor, E2A, and Pax-5 cooperate to activate the early B cell-specific mb-1 promoter
-
Sigvardsson, M. et al. Early B-cell factor, E2A, and Pax-5 cooperate to activate the early B cell-specific mb-1 promoter. Mol. Cell. Biol. 22, 8539-8551 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 8539-8551
-
-
Sigvardsson, M.1
-
51
-
-
5444222634
-
Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mob-1 transcription
-
Maier, H. et al. Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mob-1 transcription. Nature Immunol. 5, 1069-1077 (2004). This interesting paper describes the hierarchical involvement of RUNX1 and EBF in activation of the Mb-1 promoter, allowing PAX5, in turn, to activate the Mb-1 gene. The data presented agree with the model proposed in reference 49, which describes the genetic control of pre-B-cell specification.
-
(2004)
Nature Immunol.
, vol.5
, pp. 1069-1077
-
-
Maier, H.1
-
52
-
-
0032522538
-
Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments
-
Nutt, S. L., Morrison, A. M., Dorter, P., Rolink, A. & Busslinger, M. Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments. EMBO J. 17, 2319-2333 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 2319-2333
-
-
Nutt, S.L.1
Morrison, A.M.2
Dorter, P.3
Rolink, A.4
Busslinger, M.5
-
53
-
-
0027997502
-
Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
-
Urbanek, P., Wang, Z. Q., Fetka, I., Wagner, E. F. & Busslinger, M. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 79, 901-912 (1994).
-
(1994)
Cell
, vol.79
, pp. 901-912
-
-
Urbanek, P.1
Wang, Z.Q.2
Fetka, I.3
Wagner, E.F.4
Busslinger, M.5
-
54
-
-
0037023361
-
Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development
-
Kosak, S. T. et al. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 296, 158-162 (2002).
-
(2002)
Science
, vol.296
, pp. 158-162
-
-
Kosak, S.T.1
-
55
-
-
1542343974
-
Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene
-
Fuxa, M. et al. Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene. Genes Dev. 18, 411-422 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 411-422
-
-
Fuxa, M.1
-
56
-
-
0033533891
-
Commitment to the B-lymphoid lineage depends on the transcription factor Pax5
-
Nutt, S. L., Heavey, B., Rolink, A. G. & Busslinger, M. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 401, 556-562 (1999).
-
(1999)
Nature
, vol.401
, pp. 556-562
-
-
Nutt, S.L.1
Heavey, B.2
Rolink, A.G.3
Busslinger, M.4
-
57
-
-
0033533822
-
Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors
-
-/- B cells can have alternative cell fates, such as development into T cells or macrophages.
-
(1999)
Nature
, vol.401
, pp. 603-606
-
-
Rolink, A.G.1
Nutt, S.L.2
Melchers, F.3
Busslinger, M.4
-
58
-
-
0037079696
-
Multiple hematopoietic cell lineages develop in vivo from transplanted Rax5-deficient pre-BI-cell clones
-
Schaniel, C., Bruno, L., Melchers, F. & Rolink, A. G. Multiple hematopoietic cell lineages develop in vivo from transplanted Rax5-deficient pre-BI-cell clones. Blood 99, 472-478 (2002).
-
(2002)
Blood
, vol.99
, pp. 472-478
-
-
Schaniel, C.1
Bruno, L.2
Melchers, F.3
Rolink, A.G.4
-
59
-
-
0037025198
-
Reversion of B cell commitment upon loss of Pax5 expression
-
Mikkola, I., Heavey, B., Horcher, M. & Busslinger, M. Reversion of B cell commitment upon loss of Pax5 expression. Science 297, 110-113 (2002). This paper elegantly showed that ablation of PAX5 in already committed pro-B cells allows these cells to regain plasticity and differentiate into diverse cell types, such as T cells or macrophages.
-
(2002)
Science
, vol.297
, pp. 110-113
-
-
Mikkola, I.1
Heavey, B.2
Horcher, M.3
Busslinger, M.4
-
60
-
-
0034959755
-
Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis
-
Horcher, M., Souabni, A. & Busslinger, M. Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis. Immunity 14, 779-790 (2001).
-
(2001)
Immunity
, vol.14
, pp. 779-790
-
-
Horcher, M.1
Souabni, A.2
Busslinger, M.3
-
61
-
-
0036906546
-
Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1
-
Souabni, A., Cobaleda, C., Schebesta, M. & Busslinger, M. Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1. Immunity 17, 781-793 (2002).
-
(2002)
Immunity
, vol.17
, pp. 781-793
-
-
Souabni, A.1
Cobaleda, C.2
Schebesta, M.3
Busslinger, M.4
-
62
-
-
0343183096
-
Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family
-
Eberhard, D., Jimenez, G., Heavey, B. & Busslinger, M. Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family. EMBO J. 19, 2292-2303 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 2292-2303
-
-
Eberhard, D.1
Jimenez, G.2
Heavey, B.3
Busslinger, M.4
-
63
-
-
16544393313
-
Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes
-
Linderson, Y. et al. Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes. EMBO Rep. 5, 291-296 (2004).
-
(2004)
EMBO Rep.
, vol.5
, pp. 291-296
-
-
Linderson, Y.1
-
64
-
-
1542317449
-
Notch regulation of lymphocyte development and function
-
Radtke, F., Wilson, A., Mancini, S. J. & MacDonald, H. R. Notch regulation of lymphocyte development and function. Nature Immunol. 5, 247-253 (2004).
-
(2004)
Nature Immunol.
, vol.5
, pp. 247-253
-
-
Radtke, F.1
Wilson, A.2
Mancini, S.J.3
MacDonald, H.R.4
-
65
-
-
4644265888
-
Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors
-
Hoflinger, S. et al. Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. J. Immunol. 173, 3935-3944 (2004).
-
(2004)
J. Immunol.
, vol.173
, pp. 3935-3944
-
-
Hoflinger, S.1
-
66
-
-
2542455620
-
Stepwise reprogramming of B cells into macrophages
-
Xie, H., Ye, M., Feng, R. & Graf, T. Stepwise reprogramming of B cells into macrophages. Cell 117, 663-676 (2004).
-
(2004)
Cell
, vol.117
, pp. 663-676
-
-
Xie, H.1
Ye, M.2
Feng, R.3
Graf, T.4
-
67
-
-
15844362094
-
Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4
-
Schilham, M. W. et al. Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4. Nature 380, 711-714 (1996).
-
(1996)
Nature
, vol.380
, pp. 711-714
-
-
Schilham, M.W.1
-
68
-
-
0032052978
-
HMG box containing transcription factors in lymphocyte differentiation
-
Schilham, M. W. & Clevers, H. HMG box containing transcription factors in lymphocyte differentiation. Semin. Immunol. 10, 127-132 (1998).
-
(1998)
Semin. Immunol.
, vol.10
, pp. 127-132
-
-
Schilham, M.W.1
Clevers, H.2
-
69
-
-
11244305618
-
WNT signalling and haematopoiesis: A WNT-WNT situation
-
Staal, F. J. & Clevers, H. C. WNT signalling and haematopoiesis: a WNT-WNT situation. Nature Rev. Immunol. 5, 21-30 (2005).
-
(2005)
Nature Rev. Immunol.
, vol.5
, pp. 21-30
-
-
Staal, F.J.1
Clevers, H.C.2
-
70
-
-
0033711624
-
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism
-
Reya, T. et al. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity 13, 15-24 (2000).
-
(2000)
Immunity
, vol.13
, pp. 15-24
-
-
Reya, T.1
-
71
-
-
0035061538
-
IRF family of transcription factors as regulators of host defense
-
Taniguchi, T., Ogasawara, K., Takaoka, A. & Tanaka, N. IRF family of transcription factors as regulators of host defense. Annu. Rev. Immunol. 19, 623-655 (2001).
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 623-655
-
-
Taniguchi, T.1
Ogasawara, K.2
Takaoka, A.3
Tanaka, N.4
-
72
-
-
15444346834
-
Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function
-
Mittrucker, H. W. et al. Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science 275, 540-543 (1997).
-
(1997)
Science
, vol.275
, pp. 540-543
-
-
Mittrucker, H.W.1
-
73
-
-
16044369709
-
Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene
-
Holtschke, T. et al. Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell 87, 307-317 (1996).
-
(1996)
Cell
, vol.87
, pp. 307-317
-
-
Holtschke, T.1
-
74
-
-
0038506030
-
IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development
-
Lu, R., Medina, K. L., Lancki, D. W. & Singh, H. IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev. 17, 1703-1708 (2003).
-
(2003)
Genes Dev.
, vol.17
, pp. 1703-1708
-
-
Lu, R.1
Medina, K.L.2
Lancki, D.W.3
Singh, H.4
-
75
-
-
0037442214
-
Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice
-
Sun, J., Matthias, G., Mihatsch, M. J., Georgopoulos, K. & Matthias, P. Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice. J. Immunol. 170, 1699-1706 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 1699-1706
-
-
Sun, J.1
Matthias, G.2
Mihatsch, M.J.3
Georgopoulos, K.4
Matthias, P.5
-
77
-
-
0035421173
-
Regulation of BOB.1/OBF.1 stability by SIAH
-
Boehm, J., He, Y., Greiner, A., Staudt, L. & Wirth, T. Regulation of BOB.1/OBF.1 stability by SIAH. EMBO J. 20, 4153-4162 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 4153-4162
-
-
Boehm, J.1
He, Y.2
Greiner, A.3
Staudt, L.4
Wirth, T.5
-
78
-
-
0035421257
-
The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1
-
Tiedt, R., Bartholdy, B. A., Matthias, G., Newell, J. W. & Matthias, P. The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1. EMBO J. 20, 4143-4152 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 4143-4152
-
-
Tiedt, R.1
Bartholdy, B.A.2
Matthias, G.3
Newell, J.W.4
Matthias, P.5
-
79
-
-
0035099080
-
Identification and characterization of a novel OCA-B isoform: Implications for a role in B cell signaling pathways
-
Yu, X., Wang, L., Luo, Y. & Roeder, R. G. Identification and characterization of a novel OCA-B isoform: implications for a role in B cell signaling pathways. Immunity 14, 157-167 (2001).
-
(2001)
Immunity
, vol.14
, pp. 157-167
-
-
Yu, X.1
Wang, L.2
Luo, Y.3
Roeder, R.G.4
-
80
-
-
0027262608
-
Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival
-
Corcoran, L. M. et al. Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival. Genes Dev. 7, 570-582 (1993).
-
(1993)
Genes Dev.
, vol.7
, pp. 570-582
-
-
Corcoran, L.M.1
-
81
-
-
0029917392
-
The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes
-
Kim, U. et al. The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes. Nature 383, 542-547 (1996).
-
(1996)
Nature
, vol.383
, pp. 542-547
-
-
Kim, U.1
-
82
-
-
10544228521
-
B lymphocytes are impaired in mice lacking the transcriptional co-activator Bob1/OCA-B/OBF1
-
Nielsen, P. J., Georgiev, O., Lorenz, B. & Schaffner, W. B lymphocytes are impaired in mice lacking the transcriptional co-activator Bob1/OCA-B/OBF1. Eur. J. Immunol. 26, 3214-3218 (1996).
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 3214-3218
-
-
Nielsen, P.J.1
Georgiev, O.2
Lorenz, B.3
Schaffner, W.4
-
83
-
-
0029967024
-
B-cell-specific coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation
-
Schubart, D. B., Rolink, A., Kosco-Vilbois, M. H., Botteri, F. & Matthias, P. B-cell-specific coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation. Nature 383, 538-542 (1996). References 81-83 showed that the co-activator OBF1 is not essential for immunoglobulin gene transcription but rather for robust humoral immune responses and germinal-centre formation. In addition, reference 85 showed that immunoglobulin gene transcription is normal even when OBF1 and OCT2 are both absent.
-
(1996)
Nature
, vol.383
, pp. 538-542
-
-
Schubart, D.B.1
Rolink, A.2
Kosco-Vilbois, M.H.3
Botteri, F.4
Matthias, P.5
-
84
-
-
0032052935
-
Lymphoid-specific transcription mediated by the conserved octamer site: Who is doing what?
-
Matthias, P. Lymphoid-specific transcription mediated by the conserved octamer site: who is doing what? Semin. Immunol. 10, 155-163 (1998).
-
(1998)
Semin. Immunol.
, vol.10
, pp. 155-163
-
-
Matthias, P.1
-
85
-
-
0035229734
-
B cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1
-
Schubart, K. et al. B cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1. Nature Immunol. 2, 69-74 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 69-74
-
-
Schubart, K.1
-
86
-
-
0037031604
-
OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin κ genes
-
Casellas, R. et al. OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin κ genes. Cell 110, 575-585 (2002).
-
(2002)
Cell
, vol.110
, pp. 575-585
-
-
Casellas, R.1
-
87
-
-
0032191170
-
Aiolos regulates B cell activation and maturation to effector state
-
Wang, J. H. et al. Aiolos regulates B cell activation and maturation to effector state. Immunity 9, 543-553 (1998).
-
(1998)
Immunity
, vol.9
, pp. 543-553
-
-
Wang, J.H.1
-
88
-
-
0035131690
-
The B lymphocyte-specific coactivator BOB.1/OBF.1 is required at multiple stages of B-cell development
-
Hess, J., Nielsen, P. J., Fischer, K. D., Bujard, H. & Wirth, T. The B lymphocyte-specific coactivator BOB.1/OBF.1 is required at multiple stages of B-cell development. Mol. Cell. Biol. 21, 1531-1539 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1531-1539
-
-
Hess, J.1
Nielsen, P.J.2
Fischer, K.D.3
Bujard, H.4
Wirth, T.5
-
89
-
-
0033957422
-
Lack of peripheral B cells and severe agammaglobulinemia in mice simultaneously lacking Burton's tyrosine kinase and the B cell-specific transcriptional coactivator OBF-1
-
Schubart, D. B., Rolink, A., Schubart, K. & Matthias, P. Lack of peripheral B cells and severe agammaglobulinemia in mice simultaneously lacking Burton's tyrosine kinase and the B cell-specific transcriptional coactivator OBF-1. J. Immunol. 164, 18-22 (2000).
-
(2000)
J. Immunol.
, vol.164
, pp. 18-22
-
-
Schubart, D.B.1
Rolink, A.2
Schubart, K.3
Matthias, P.4
-
90
-
-
0036889190
-
BOB.1/OBF.1 deficiency affects marginal-zone B-cell compartment
-
Samardzic, T., Marinkovic, D., Nielsen, P. J., Nitschke, L. & Wirth, T. BOB.1/OBF.1 deficiency affects marginal-zone B-cell compartment. Mol. Cell. Biol. 22, 8320-8331 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 8320-8331
-
-
Samardzic, T.1
Marinkovic, D.2
Nielsen, P.J.3
Nitschke, L.4
Wirth, T.5
-
91
-
-
0028535406
-
Oct-2 is required early in T cell-independent B cell activation for G1 progression and for proliferation
-
Corcoran, L. M. & Karvelas, M. Oct-2 is required early in T cell-independent B cell activation for G1 progression and for proliferation. Immunity 1, 635-645 (1994).
-
(1994)
Immunity
, vol.1
, pp. 635-645
-
-
Corcoran, L.M.1
Karvelas, M.2
-
92
-
-
0031296659
-
Oct-2 gene disruption eliminates the peritoneal B-1 lymphocyte lineage and attenuates B-2 cell maturation and function
-
Humbert, P. O. & Corcoran, L. M. Oct-2 gene disruption eliminates the peritoneal B-1 lymphocyte lineage and attenuates B-2 cell maturation and function. J. Immunol. 159, 5273-5284 (1997).
-
(1997)
J. Immunol.
, vol.159
, pp. 5273-5284
-
-
Humbert, P.O.1
Corcoran, L.M.2
-
93
-
-
1242319300
-
B cell development and immunoglobulin transcription in Oct-1-deficient mice
-
Wang, V. E., Tantin, D., Chen, J. & Sharp, P. A. B cell development and immunoglobulin transcription in Oct-1-deficient mice. Proc. Natl Acad. Sci. USA 101, 2005-2010 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2005-2010
-
-
Wang, V.E.1
Tantin, D.2
Chen, J.3
Sharp, P.A.4
-
94
-
-
0031897632
-
NF-κB Rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh, S., May, M. J. & Kopp, E. B. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16, 225-260 (1998).
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
95
-
-
0036234459
-
Missing pieces in the NF-κB puzzle
-
Ghosh, S. & Karin, M. Missing pieces in the NF-κB puzzle. Cell 109, S81-S96 (2002).
-
(2002)
Cell
, vol.109
-
-
Ghosh, S.1
Karin, M.2
-
96
-
-
4444376712
-
Signaling to NF-κB
-
Hayden, M. S. & Ghosh, S. Signaling to NF-κB. Genes Dev. 18, 2195-2224 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
97
-
-
0028804551
-
Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses
-
Sha, W. C., Liou, H. C., Tuomanen, E. I. & Baltimore, D. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell 80, 321-330 (1995). This was the first study to identify the multiple in vivo roles of NF-κB. This paper also revealed that NF-κB is not required for Igκ light-chain rearrangement and transcription.
-
(1995)
Cell
, vol.80
, pp. 321-330
-
-
Sha, W.C.1
Liou, H.C.2
Tuomanen, E.I.3
Baltimore, D.4
-
98
-
-
0034676014
-
Nuclear factor κB is required for the development of marginal zone B lymphocytes
-
Cariappa, A., Liou, H. C., Horwitz, B. H. & Pillai, S. Nuclear factor κB is required for the development of marginal zone B lymphocytes. J. Exp. Med. 192, 1175-1182 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1175-1182
-
-
Cariappa, A.1
Liou, H.C.2
Horwitz, B.H.3
Pillai, S.4
-
100
-
-
0037097665
-
BLyS enables survival of transitional and mature B cells through distinct mediators
-
Hsu, B. L., Harless, S. M., Lindsley, R. C., Hilbert, D. M. & Cancro, M. P. BLyS enables survival of transitional and mature B cells through distinct mediators. J. Immunol. 168, 5993-5996 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 5993-5996
-
-
Hsu, B.L.1
Harless, S.M.2
Lindsley, R.C.3
Hilbert, D.M.4
Cancro, M.P.5
-
101
-
-
0035881959
-
Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines
-
Weih, D. S., Yilmaz, Z. B. & Weih, F. Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines. J. Immunol. 167, 1909-1919 (2001).
-
(2001)
J. Immunol.
, vol.167
, pp. 1909-1919
-
-
Weih, D.S.1
Yilmaz, Z.B.2
Weih, F.3
-
102
-
-
15444357762
-
Requirement for NF-κB in osteoclast and B-cell development
-
Franzoso, G. et al. Requirement for NF-κB in osteoclast and B-cell development. Genes Dev. 11, 3482-3496 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 3482-3496
-
-
Franzoso, G.1
-
103
-
-
0034423508
-
The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression
-
Grossmann, M. et al. The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression. EMBO J. 19, 6351-6360 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 6351-6360
-
-
Grossmann, M.1
-
104
-
-
0034995180
-
The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21
-
Cariappa, A. et al. The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21. Immunity 14, 603-615 (2001). This paper proposed a model in which the level of BCR signalling is a key determinant of differentiation into marginal-zone B cells, and it identified Aiolos as one of the essential factors in this process.
-
(2001)
Immunity
, vol.14
, pp. 603-615
-
-
Cariappa, A.1
-
105
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke, R et al. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10, 547-558 (1999).
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, R.1
-
106
-
-
0036094254
-
Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells
-
Tanigaki, K. et al. Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells. Nature Immunol. 3, 443-450 (2002).
-
(2002)
Nature Immunol.
, vol.3
, pp. 443-450
-
-
Tanigaki, K.1
-
107
-
-
0037332254
-
Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway
-
Kuroda, K. et al. Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway. Immunity 18, 301-312 (2003).
-
(2003)
Immunity
, vol.18
, pp. 301-312
-
-
Kuroda, K.1
-
108
-
-
0038742790
-
Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development
-
Saito, T. et al. Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development. Immunity 18, 675-685 (2003).
-
(2003)
Immunity
, vol.18
, pp. 675-685
-
-
Saito, T.1
-
109
-
-
0033118724
-
PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction
-
Garrett-Sinha, L. A. et al. PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction. Immunity 10, 399-408 (1999).
-
(1999)
Immunity
, vol.10
, pp. 399-408
-
-
Garrett-Sinha, L.A.1
-
110
-
-
0034748923
-
PU.1/Spi-B regulation of c-rel is essential for mature B cell survival
-
Hu, C. J. et al. PU.1/Spi-B regulation of c-rel is essential for mature B cell survival. Immunity 15, 545-555 (2001).
-
(2001)
Immunity
, vol.15
, pp. 545-555
-
-
Hu, C.J.1
-
111
-
-
5044220453
-
A stepwise epigenetic process controls immunoglobulin allelic exclusion
-
Bergman, Y. & Cedar, H. A stepwise epigenetic process controls immunoglobulin allelic exclusion. Nature Rev. Immunol. 4, 753-761 (2004).
-
(2004)
Nature Rev. Immunol.
, vol.4
, pp. 753-761
-
-
Bergman, Y.1
Cedar, H.2
-
112
-
-
4644329449
-
Circulating hematopoietic progenitors with T lineage potential
-
Schwarz, B. A. & Bhandoola, A. Circulating hematopoietic progenitors with T lineage potential. Nature Immunol. 5, 953-960 (2004).
-
(2004)
Nature Immunol.
, vol.5
, pp. 953-960
-
-
Schwarz, B.A.1
Bhandoola, A.2
-
114
-
-
0037232245
-
Essential role of Id2 in negative regulation of IgE class switching
-
Sugai, M. et al. Essential role of Id2 in negative regulation of IgE class switching. Nature Immunol. 4, 25-30 (2002).
-
(2002)
Nature Immunol.
, vol.4
, pp. 25-30
-
-
Sugai, M.1
|