메뉴 건너뛰기




Volumn 253, Issue 1, 2013, Pages 53-64

MicroRNA regulation of T-cell development

Author keywords

Cell differentiation; Dendritic cells; Gene regulation; T cells; Th1 Th2 Th17 cells; Thymus

Indexed keywords

ALPHA INTERFERON; DICER; MICRORNA; MICRORNA 128; MICRORNA 21; MICRORNA 27B; NOTCH RECEPTOR; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

EID: 84875769973     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12049     Document Type: Review
Times cited : (54)

References (105)
  • 2
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 2010;466:835-840.
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 4
    • 70349320089 scopus 로고    scopus 로고
    • MicroRNAs and metazoan macroevolution: insights into canalization, complexity, and the Cambrian explosion
    • Peterson KJ, Dietrich MR, McPeek MA. MicroRNAs and metazoan macroevolution: insights into canalization, complexity, and the Cambrian explosion. BioEssays 2009;31:736-747.
    • (2009) BioEssays , vol.31 , pp. 736-747
    • Peterson, K.J.1    Dietrich, M.R.2    McPeek, M.A.3
  • 5
    • 84859403817 scopus 로고    scopus 로고
    • Dynamic microRNA gene transcription and processing during T cell development
    • Kirigin FF, et al. Dynamic microRNA gene transcription and processing during T cell development. J Immunol 2012;188:3257-3267.
    • (2012) J Immunol , vol.188 , pp. 3257-3267
    • Kirigin, F.F.1
  • 6
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
    • Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB. Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites. Science 2008;320:1643-1647.
    • (2008) Science , vol.320 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 7
    • 41649089309 scopus 로고    scopus 로고
    • The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution
    • Okamura K, Phillips MD, Tyler DM, Duan H, Chou YT, Lai EC. The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution. Nat Struct Mol Biol 2008;15:354-363.
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 354-363
    • Okamura, K.1    Phillips, M.D.2    Tyler, D.M.3    Duan, H.4    Chou, Y.T.5    Lai, E.C.6
  • 8
    • 78650668809 scopus 로고    scopus 로고
    • miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells
    • Zhou H, et al. miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells. Blood 2010;116:5885-5894.
    • (2010) Blood , vol.116 , pp. 5885-5894
    • Zhou, H.1
  • 9
    • 79955967742 scopus 로고    scopus 로고
    • miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1
    • Lu C, et al. miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1. Blood 2011;117:4293-4303.
    • (2011) Blood , vol.117 , pp. 4293-4303
    • Lu, C.1
  • 10
    • 33947104955 scopus 로고    scopus 로고
    • Dynamic regulation of miRNA expression in ordered stages of cellular development
    • Neilson JR, Zheng GX, Burge CB, Sharp PA. Dynamic regulation of miRNA expression in ordered stages of cellular development. Genes Dev 2007;21:578-589.
    • (2007) Genes Dev , vol.21 , pp. 578-589
    • Neilson, J.R.1    Zheng, G.X.2    Burge, C.B.3    Sharp, P.A.4
  • 11
    • 20844432885 scopus 로고    scopus 로고
    • T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer
    • Cobb BS, et al. T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer. J Exp Med 2005;201:1367-1373.
    • (2005) J Exp Med , vol.201 , pp. 1367-1373
    • Cobb, B.S.1
  • 12
    • 46249103136 scopus 로고    scopus 로고
    • Unravelling the association of partial T-cell immunodeficiency and immune dysregulation
    • Liston A, Enders A, Siggs OM. Unravelling the association of partial T-cell immunodeficiency and immune dysregulation. Nat Rev Immunol 2008;8:545-558.
    • (2008) Nat Rev Immunol , vol.8 , pp. 545-558
    • Liston, A.1    Enders, A.2    Siggs, O.M.3
  • 15
    • 84866179216 scopus 로고    scopus 로고
    • Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1
    • Fragoso R, et al. Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1. PLoS Genet 2012;8:e1002855.
    • (2012) PLoS Genet , vol.8
    • Fragoso, R.1
  • 16
    • 33947721625 scopus 로고    scopus 로고
    • miR-181a is an intrinsic modulator of T cell sensitivity and selection
    • Li QJ, et al. miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 2007;129:147-161.
    • (2007) Cell , vol.129 , pp. 147-161
    • Li, Q.J.1
  • 17
    • 70350435670 scopus 로고    scopus 로고
    • An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a
    • Ebert PJ, Jiang S, Xie J, Li QJ, Davis MM. An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. Nat Immunol 2009;10:1162-1169.
    • (2009) Nat Immunol , vol.10 , pp. 1162-1169
    • Ebert, P.J.1    Jiang, S.2    Xie, J.3    Li, Q.J.4    Davis, M.M.5
  • 18
    • 61749100637 scopus 로고    scopus 로고
    • Sant'angelo D, Sadelain M. Harnessing endogenous miR-181a to segregate transgenic antigen receptor expression in developing versus post-thymic T cells in murine hematopoietic chimeras
    • Papapetrou EP, Kovalovsky D, Beloeil L. Sant'angelo D, Sadelain M. Harnessing endogenous miR-181a to segregate transgenic antigen receptor expression in developing versus post-thymic T cells in murine hematopoietic chimeras. J Clin Invest 2009;119:157-168.
    • (2009) J Clin Invest , vol.119 , pp. 157-168
    • Papapetrou, E.P.1    Kovalovsky, D.2    Beloeil, L.3
  • 19
    • 84862776981 scopus 로고    scopus 로고
    • Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis
    • Yuan J, Nguyen CK, Liu X, Kanellopoulou C, Muljo SA. Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis. Science 2012;335:1195-1200.
    • (2012) Science , vol.335 , pp. 1195-1200
    • Yuan, J.1    Nguyen, C.K.2    Liu, X.3    Kanellopoulou, C.4    Muljo, S.A.5
  • 20
    • 0028233225 scopus 로고
    • Steroid production in the thymus: implications for thymocyte selection
    • Vacchio MS, Papadopoulos V, Ashwell JD. Steroid production in the thymus: implications for thymocyte selection. J Exp Med 1994;179:1835-1846.
    • (1994) J Exp Med , vol.179 , pp. 1835-1846
    • Vacchio, M.S.1    Papadopoulos, V.2    Ashwell, J.D.3
  • 21
    • 0034049874 scopus 로고    scopus 로고
    • Glucocorticoids in T cell development and function
    • Ashwell JD, Lu FW, Vacchio MS. Glucocorticoids in T cell development and function. Annu Rev Immunol 2000;18:309-345.
    • (2000) Annu Rev Immunol , vol.18 , pp. 309-345
    • Ashwell, J.D.1    Lu, F.W.2    Vacchio, M.S.3
  • 22
    • 78449239272 scopus 로고    scopus 로고
    • Glucocorticoids modulate microRNA expression and processing during lymphocyte apoptosis
    • Smith LK, Shah RR, Cidlowski JA. Glucocorticoids modulate microRNA expression and processing during lymphocyte apoptosis. J Biol Chem 2010;285:36698-36708.
    • (2010) J Biol Chem , vol.285 , pp. 36698-36708
    • Smith, L.K.1    Shah, R.R.2    Cidlowski, J.A.3
  • 23
    • 84861656218 scopus 로고    scopus 로고
    • Thymic epithelial cells: working class heroes for T cell development and repertoire selection
    • Anderson G, Takahama Y. Thymic epithelial cells: working class heroes for T cell development and repertoire selection. Trends Immunol 2012;33:256-263.
    • (2012) Trends Immunol , vol.33 , pp. 256-263
    • Anderson, G.1    Takahama, Y.2
  • 24
    • 84855931651 scopus 로고    scopus 로고
    • The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-alpha receptor
    • Papadopoulou AS, et al. The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-alpha receptor. Nat Immunol 2012;13:181-187.
    • (2012) Nat Immunol , vol.13 , pp. 181-187
    • Papadopoulou, A.S.1
  • 25
    • 84867287351 scopus 로고    scopus 로고
    • MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection
    • Zuklys S, et al. MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection. J Immunol 2012;189:3894-3904.
    • (2012) J Immunol , vol.189 , pp. 3894-3904
    • Zuklys, S.1
  • 26
    • 77952336147 scopus 로고    scopus 로고
    • Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus
    • Anz D, et al. Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus. J Immunol 2009;182:6044-6050.
    • (2009) J Immunol , vol.182 , pp. 6044-6050
    • Anz, D.1
  • 27
    • 80051890269 scopus 로고    scopus 로고
    • MicroRNA-29 regulates T-box transcription factors and interferon-gamma production in helper T cells
    • Steiner DF, et al. MicroRNA-29 regulates T-box transcription factors and interferon-gamma production in helper T cells. Immunity 2011;35:169-181.
    • (2011) Immunity , vol.35 , pp. 169-181
    • Steiner, D.F.1
  • 28
    • 39749163245 scopus 로고    scopus 로고
    • Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes
    • Xiao C, et al. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol 2008;9:405-414.
    • (2008) Nat Immunol , vol.9 , pp. 405-414
    • Xiao, C.1
  • 29
    • 75649108622 scopus 로고    scopus 로고
    • An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes
    • Curtale G, et al. An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes. Blood 2010;115:265-273.
    • (2010) Blood , vol.115 , pp. 265-273
    • Curtale, G.1
  • 30
    • 84856630441 scopus 로고    scopus 로고
    • Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice
    • Tian L, et al. Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice. J Autoimmun 2012;38:39-48.
    • (2012) J Autoimmun , vol.38 , pp. 39-48
    • Tian, L.1
  • 31
    • 84870293512 scopus 로고    scopus 로고
    • Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
    • Li G, et al. Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. Nat Med 2012;18:1518-1524.
    • (2012) Nat Med , vol.18 , pp. 1518-1524
    • Li, G.1
  • 32
    • 77955508072 scopus 로고    scopus 로고
    • Costimulation-dependent expression of microRNA-214 increases the ability of T cells to proliferate by targeting Pten
    • Jindra PT, Bagley J, Godwin JG, Iacomini J. Costimulation-dependent expression of microRNA-214 increases the ability of T cells to proliferate by targeting Pten. J Immunol 2010;185:990-997.
    • (2010) J Immunol , vol.185 , pp. 990-997
    • Jindra, P.T.1    Bagley, J.2    Godwin, J.G.3    Iacomini, J.4
  • 33
    • 84864754110 scopus 로고    scopus 로고
    • miR-9 enhances IL-2 production in activated human CD4(+) T cells by repressing Blimp-1
    • Thiele S, Wittmann J, Jack HM, Pahl A. miR-9 enhances IL-2 production in activated human CD4(+) T cells by repressing Blimp-1. Eur J Immunol 2012;42:2100-2108.
    • (2012) Eur J Immunol , vol.42 , pp. 2100-2108
    • Thiele, S.1    Wittmann, J.2    Jack, H.M.3    Pahl, A.4
  • 34
    • 77958149675 scopus 로고    scopus 로고
    • The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes
    • Stittrich AB, et al. The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes. Nat Immunol 2010;11:1057-1062.
    • (2010) Nat Immunol , vol.11 , pp. 1057-1062
    • Stittrich, A.B.1
  • 35
    • 79959784552 scopus 로고    scopus 로고
    • Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression
    • Stagakis E, et al. Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression. Ann Rheum Dis 2011;70:1496-1506.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1496-1506
    • Stagakis, E.1
  • 36
    • 80052659396 scopus 로고    scopus 로고
    • MicroRNA regulation of molecular networks mapped by global microRNA, mRNA, and protein expression in activated T lymphocytes
    • Grigoryev YA, et al. MicroRNA regulation of molecular networks mapped by global microRNA, mRNA, and protein expression in activated T lymphocytes. J Immunol 2011;187:2233-2243.
    • (2011) J Immunol , vol.187 , pp. 2233-2243
    • Grigoryev, Y.A.1
  • 37
    • 77957888270 scopus 로고    scopus 로고
    • MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood
    • Cox MB, et al. MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood. PLoS ONE 2010;5:e12132.
    • (2010) PLoS ONE , vol.5
    • Cox, M.B.1
  • 38
    • 78650619708 scopus 로고    scopus 로고
    • Human activated CD4(+) T lymphocytes increase IL-2 expression by downregulating microRNA-181c
    • Xue Q, et al. Human activated CD4(+) T lymphocytes increase IL-2 expression by downregulating microRNA-181c. Mol Immunol 2010;48:592-599.
    • (2010) Mol Immunol , vol.48 , pp. 592-599
    • Xue, Q.1
  • 39
    • 84866354593 scopus 로고    scopus 로고
    • miR-146a controls the resolution of T cell responses in mice
    • Yang L, et al. miR-146a controls the resolution of T cell responses in mice. J Exp Med 2012;209:1655-1670.
    • (2012) J Exp Med , vol.209 , pp. 1655-1670
    • Yang, L.1
  • 40
    • 80052035077 scopus 로고    scopus 로고
    • Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4 + T cells by the microRNA miR-125b
    • Rossi RL, et al. Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4 + T cells by the microRNA miR-125b. Nat Immunol 2011;12:796-803.
    • (2011) Nat Immunol , vol.12 , pp. 796-803
    • Rossi, R.L.1
  • 41
    • 69249208597 scopus 로고    scopus 로고
    • microRNA 184 regulates expression of NFAT1 in umbilical cord blood CD4 + T cells
    • Weitzel RP, et al. microRNA 184 regulates expression of NFAT1 in umbilical cord blood CD4 + T cells. Blood 2009;113:6648-6657.
    • (2009) Blood , vol.113 , pp. 6648-6657
    • Weitzel, R.P.1
  • 42
    • 78650754295 scopus 로고    scopus 로고
    • Dicer controls CD8 + T-cell activation, migration, and survival
    • Zhang N, Bevan MJ. Dicer controls CD8 + T-cell activation, migration, and survival. Proc Natl Acad Sci USA 2010;107:21629-21634.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 21629-21634
    • Zhang, N.1    Bevan, M.J.2
  • 43
    • 84862533928 scopus 로고    scopus 로고
    • Temporal expression of microRNA cluster miR-17-92 regulates effector and memory CD8 + T-cell differentiation
    • Wu T, et al. Temporal expression of microRNA cluster miR-17-92 regulates effector and memory CD8 + T-cell differentiation. Proc Natl Acad Sci USA 2012;109:9965-9970.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 9965-9970
    • Wu, T.1
  • 44
    • 84859389554 scopus 로고    scopus 로고
    • Downregulation of inflammatory microRNAs by Ig-like transcript 3 is essential for the differentiation of human CD8(+) T suppressor cells
    • Chang CC, Zhang QY, Liu Z, Clynes RA, Suciu-Foca N, Vlad G. Downregulation of inflammatory microRNAs by Ig-like transcript 3 is essential for the differentiation of human CD8(+) T suppressor cells. J Immunol 2012;188:3042-3052.
    • (2012) J Immunol , vol.188 , pp. 3042-3052
    • Chang, C.C.1    Zhang, Q.Y.2    Liu, Z.3    Clynes, R.A.4    Suciu-Foca, N.5    Vlad, G.6
  • 45
    • 33750499991 scopus 로고    scopus 로고
    • A role for Dicer in immune regulation
    • Cobb BS, et al. A role for Dicer in immune regulation. J Exp Med 2006;203:2519-2527.
    • (2006) J Exp Med , vol.203 , pp. 2519-2527
    • Cobb, B.S.1
  • 46
    • 80052033649 scopus 로고    scopus 로고
    • The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma
    • Ma F, et al. The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma. Nat Immunol 2011;12:861-869.
    • (2011) Nat Immunol , vol.12 , pp. 861-869
    • Ma, F.1
  • 47
    • 84864812650 scopus 로고    scopus 로고
    • miR-29ab1 deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis
    • Smith KM, et al. miR-29ab1 deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis. J Immunol 2012;189:1567-1576.
    • (2012) J Immunol , vol.189 , pp. 1567-1576
    • Smith, K.M.1
  • 49
    • 70549095099 scopus 로고    scopus 로고
    • Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease
    • Mattes J, Collison A, Plank M, Phipps S, Foster PS. Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease. Proc Natl Acad Sci USA 2009;106:18704-18709.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 18704-18709
    • Mattes, J.1    Collison, A.2    Plank, M.3    Phipps, S.4    Foster, P.S.5
  • 50
    • 34247584465 scopus 로고    scopus 로고
    • Requirement of bic/microRNA-155 for normal immune function
    • Rodriguez A, et al. Requirement of bic/microRNA-155 for normal immune function. Science 2007;316:608-611.
    • (2007) Science , vol.316 , pp. 608-611
    • Rodriguez, A.1
  • 51
    • 84872488543 scopus 로고    scopus 로고
    • MicroRNA let-7e is associated with the pathogenesis of experimental autoimmune encephalomyelitis
    • Guan H, et al. MicroRNA let-7e is associated with the pathogenesis of experimental autoimmune encephalomyelitis. Eur J Immunol 2013;43:104-114.
    • (2013) Eur J Immunol , vol.43 , pp. 104-114
    • Guan, H.1
  • 52
    • 83755186512 scopus 로고    scopus 로고
    • Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity
    • Guerau-de-Arellano M, et al. Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity. Brain 2011;134:3578-3589.
    • (2011) Brain , vol.134 , pp. 3578-3589
    • Guerau-de-Arellano, M.1
  • 53
    • 70449716915 scopus 로고    scopus 로고
    • MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis
    • Du C, et al. MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol 2009;10:1252-1259.
    • (2009) Nat Immunol , vol.10 , pp. 1252-1259
    • Du, C.1
  • 55
    • 84867584246 scopus 로고    scopus 로고
    • MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1
    • Yao R, et al. MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1. PLoS ONE 2012;7:e46082.
    • (2012) PLoS ONE , vol.7
    • Yao, R.1
  • 56
    • 80053505393 scopus 로고    scopus 로고
    • MicroRNA-155 is essential for the T cell-mediated control of Helicobacter pylori infection and for the induction of chronic Gastritis and Colitis
    • Oertli M, Engler DB, Kohler E, Koch M, Meyer TF, Muller A. MicroRNA-155 is essential for the T cell-mediated control of Helicobacter pylori infection and for the induction of chronic Gastritis and Colitis. J Immunol 2011;187:3578-3586.
    • (2011) J Immunol , vol.187 , pp. 3578-3586
    • Oertli, M.1    Engler, D.B.2    Kohler, E.3    Koch, M.4    Meyer, T.F.5    Muller, A.6
  • 57
    • 80052661268 scopus 로고    scopus 로고
    • Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis
    • Murugaiyan G, Beynon V, Mittal A, Joller N, Weiner HL. Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis. J Immunol 2011;187:2213-2221.
    • (2011) J Immunol , vol.187 , pp. 2213-2221
    • Murugaiyan, G.1    Beynon, V.2    Mittal, A.3    Joller, N.4    Weiner, H.L.5
  • 58
    • 34548036949 scopus 로고    scopus 로고
    • Germinal-center organization and cellular dynamics
    • Allen CD, Okada T, Cyster JG. Germinal-center organization and cellular dynamics. Immunity 2007;27:190-202.
    • (2007) Immunity , vol.27 , pp. 190-202
    • Allen, C.D.1    Okada, T.2    Cyster, J.G.3
  • 59
    • 79958255209 scopus 로고    scopus 로고
    • A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center
    • Schwickert TA, et al. A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center. J Exp Med 2011;208:1243-1252.
    • (2011) J Exp Med , vol.208 , pp. 1243-1252
    • Schwickert, T.A.1
  • 60
    • 84859720726 scopus 로고    scopus 로고
    • T-follicular helper cell differentiation and the co-option of this pathway by non-helper cells
    • Linterman MA, Liston A, Vinuesa CG. T-follicular helper cell differentiation and the co-option of this pathway by non-helper cells. Immunol Rev 2012;247:143-159.
    • (2012) Immunol Rev , vol.247 , pp. 143-159
    • Linterman, M.A.1    Liston, A.2    Vinuesa, C.G.3
  • 61
    • 84864865405 scopus 로고    scopus 로고
    • Decreased microRNA-142-3p/5p expression causes CD4 + T cell activation and B cell hyperstimulation in systemic lupus erythematosus
    • Ding S, et al. Decreased microRNA-142-3p/5p expression causes CD4 + T cell activation and B cell hyperstimulation in systemic lupus erythematosus. Arthritis Rheum 2012;64:2953-2963.
    • (2012) Arthritis Rheum , vol.64 , pp. 2953-2963
    • Ding, S.1
  • 62
    • 36048946330 scopus 로고    scopus 로고
    • Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA
    • Yu D, et al. Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA. Nature 2007;450:299-303.
    • (2007) Nature , vol.450 , pp. 299-303
    • Yu, D.1
  • 63
    • 70449490395 scopus 로고    scopus 로고
    • Lineage specification and heterogeneity of T follicular helper cells
    • Yu D, Batten M, Mackay CR, King C. Lineage specification and heterogeneity of T follicular helper cells. Curr Opin Immunol 2009;21:619-625.
    • (2009) Curr Opin Immunol , vol.21 , pp. 619-625
    • Yu, D.1    Batten, M.2    Mackay, C.R.3    King, C.4
  • 64
    • 84858986644 scopus 로고    scopus 로고
    • MicroRNA profile of circulating CD4-positive regulatory T cells in human adults and impact of differentially expressed microRNAs on expression of two genes essential to their function
    • Fayyad-Kazan H, et al. MicroRNA profile of circulating CD4-positive regulatory T cells in human adults and impact of differentially expressed microRNAs on expression of two genes essential to their function. J Biol Chem 2012;287:9910-9922.
    • (2012) J Biol Chem , vol.287 , pp. 9910-9922
    • Fayyad-Kazan, H.1
  • 65
    • 67649528173 scopus 로고    scopus 로고
    • Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression
    • Rouas R, et al. Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression. Eur J Immunol 2009;39:1608-1618.
    • (2009) Eur J Immunol , vol.39 , pp. 1608-1618
    • Rouas, R.1
  • 66
    • 51049110261 scopus 로고    scopus 로고
    • Dicer-dependent microRNA pathway safeguards regulatory T cell function
    • Liston A, Lu LF, O'Carroll D, Tarakhovsky A, Rudensky AY. Dicer-dependent microRNA pathway safeguards regulatory T cell function. J Exp Med 2008;205:1993-2004.
    • (2008) J Exp Med , vol.205 , pp. 1993-2004
    • Liston, A.1    Lu, L.F.2    O'Carroll, D.3    Tarakhovsky, A.4    Rudensky, A.Y.5
  • 67
    • 84862106790 scopus 로고    scopus 로고
    • MicroRNA 10a marks regulatory T cells
    • Jeker LT, et al. MicroRNA 10a marks regulatory T cells. PLoS ONE 2012;7:e36684.
    • (2012) PLoS ONE , vol.7
    • Jeker, L.T.1
  • 68
    • 84861230795 scopus 로고    scopus 로고
    • TGF-beta and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells
    • Takahashi H, et al. TGF-beta and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells. Nat Immunol 2012;13:587-595.
    • (2012) Nat Immunol , vol.13 , pp. 587-595
    • Takahashi, H.1
  • 69
    • 37049019860 scopus 로고    scopus 로고
    • Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions
    • Siggs OM, et al. Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions. Immunity 2007;27:912-926.
    • (2007) Immunity , vol.27 , pp. 912-926
    • Siggs, O.M.1
  • 70
    • 64849100152 scopus 로고    scopus 로고
    • Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells
    • Kohlhaas S, Garden OA, Scudamore C, Turner M, Okkenhaug K, Vigorito E. Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells. J Immunol 2009;182:2578-2582.
    • (2009) J Immunol , vol.182 , pp. 2578-2582
    • Kohlhaas, S.1    Garden, O.A.2    Scudamore, C.3    Turner, M.4    Okkenhaug, K.5    Vigorito, E.6
  • 71
    • 58149268107 scopus 로고    scopus 로고
    • Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein
    • Lu LF, et al. Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein. Immunity 2009;30:80-91.
    • (2009) Immunity , vol.30 , pp. 80-91
    • Lu, L.F.1
  • 72
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol 2005;6:1142-1151.
    • (2005) Nat Immunol , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 73
    • 34249933446 scopus 로고    scopus 로고
    • Tracing the action of IL-2 in tolerance to islet-specific antigen
    • Liston A, Siggs OM, Goodnow CC. Tracing the action of IL-2 in tolerance to islet-specific antigen. Immunol Cell Biol 2007;85:338-342.
    • (2007) Immunol Cell Biol , vol.85 , pp. 338-342
    • Liston, A.1    Siggs, O.M.2    Goodnow, C.C.3
  • 74
    • 27544446622 scopus 로고    scopus 로고
    • Development and function of agonist-induced CD25 + Foxp3 + regulatory T cells in the absence of interleukin 2 signaling
    • D'Cruz LM, Klein L. Development and function of agonist-induced CD25 + Foxp3 + regulatory T cells in the absence of interleukin 2 signaling. Nat Immunol 2005;6:1152-1159.
    • (2005) Nat Immunol , vol.6 , pp. 1152-1159
    • D'Cruz, L.M.1    Klein, L.2
  • 75
    • 51049089025 scopus 로고    scopus 로고
    • The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease
    • Chong MM, Rasmussen JP, Rudensky AY, Littman DR. The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease. J Exp Med 2008;205:2005-2017.
    • (2008) J Exp Med , vol.205 , pp. 2005-2017
    • Chong, M.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3    Littman, D.R.4
  • 76
    • 51049120236 scopus 로고    scopus 로고
    • Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity
    • Zhou X, et al. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J Exp Med 2008;205:1983-1991.
    • (2008) J Exp Med , vol.205 , pp. 1983-1991
    • Zhou, X.1
  • 77
    • 79251576804 scopus 로고    scopus 로고
    • Dicer insufficiency and microRNA-155 overexpression in lupus regulatory T cells: an apparent paradox in the setting of an inflammatory milieu
    • Divekar AA, Dubey S, Gangalum PR, Singh RR. Dicer insufficiency and microRNA-155 overexpression in lupus regulatory T cells: an apparent paradox in the setting of an inflammatory milieu. J Immunol 2010;186:924-930.
    • (2010) J Immunol , vol.186 , pp. 924-930
    • Divekar, A.A.1    Dubey, S.2    Gangalum, P.R.3    Singh, R.R.4
  • 78
    • 0034161939 scopus 로고    scopus 로고
    • The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development
    • Alvarez JD, Yasui DH, Niida H, Joh T, Loh DY, Kohwi-Shigematsu T. The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development. Genes Dev 2000;14:521-535.
    • (2000) Genes Dev , vol.14 , pp. 521-535
    • Alvarez, J.D.1    Yasui, D.H.2    Niida, H.3    Joh, T.4    Loh, D.Y.5    Kohwi-Shigematsu, T.6
  • 79
    • 33750465872 scopus 로고    scopus 로고
    • SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes
    • Cai S, Lee CC, Kohwi-Shigematsu T. SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. Nat Genet 2006;38:1278-1288.
    • (2006) Nat Genet , vol.38 , pp. 1278-1288
    • Cai, S.1    Lee, C.C.2    Kohwi-Shigematsu, T.3
  • 80
    • 84866533054 scopus 로고    scopus 로고
    • A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells
    • Fu W, et al. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol 2012;13:972-980.
    • (2012) Nat Immunol , vol.13 , pp. 972-980
    • Fu, W.1
  • 81
    • 80052023563 scopus 로고    scopus 로고
    • Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation
    • Beyer M, et al. Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol 2011;12:898-907.
    • (2011) Nat Immunol , vol.12 , pp. 898-907
    • Beyer, M.1
  • 82
    • 77956632634 scopus 로고    scopus 로고
    • Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses
    • Lu LF, et al. Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses. Cell 2010;142:914-929.
    • (2010) Cell , vol.142 , pp. 914-929
    • Lu, L.F.1
  • 83
    • 59649119933 scopus 로고    scopus 로고
    • miR-142-3p restricts cAMP production in CD4 + CD25- T cells and CD4 + CD25 + TREG cells by targeting AC9 mRNA
    • Huang B, et al. miR-142-3p restricts cAMP production in CD4 + CD25- T cells and CD4 + CD25 + TREG cells by targeting AC9 mRNA. EMBO Rep 2009;10:180-185.
    • (2009) EMBO Rep , vol.10 , pp. 180-185
    • Huang, B.1
  • 84
    • 77956198304 scopus 로고    scopus 로고
    • Dicer-dependent microRNAs control maturation, function, and maintenance of Langerhans cells in vivo
    • Kuipers H, Schnorfeil FM, Fehling HJ, Bartels H, Brocker T. Dicer-dependent microRNAs control maturation, function, and maintenance of Langerhans cells in vivo. J Immunol 2010;185:400-409.
    • (2010) J Immunol , vol.185 , pp. 400-409
    • Kuipers, H.1    Schnorfeil, F.M.2    Fehling, H.J.3    Bartels, H.4    Brocker, T.5
  • 85
    • 79955967932 scopus 로고    scopus 로고
    • Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function
    • Dunand-Sauthier I, et al. Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function. Blood 2011;117:4490-4500.
    • (2011) Blood , vol.117 , pp. 4490-4500
    • Dunand-Sauthier, I.1
  • 86
    • 80051925149 scopus 로고    scopus 로고
    • Inhibition of microRNA let-7i depresses maturation and functional state of dendritic cells in response to lipopolysaccharide stimulation via targeting suppressor of cytokine signaling 1
    • Zhang M, et al. Inhibition of microRNA let-7i depresses maturation and functional state of dendritic cells in response to lipopolysaccharide stimulation via targeting suppressor of cytokine signaling 1. J Immunol 2011;187:1674-1683.
    • (2011) J Immunol , vol.187 , pp. 1674-1683
    • Zhang, M.1
  • 87
    • 84861210976 scopus 로고    scopus 로고
    • Dicer1 deletion in myeloid-committed progenitors causes neutrophil dysplasia and blocks macrophage/dendritic cell development in mice
    • Alemdehy MF, et al. Dicer1 deletion in myeloid-committed progenitors causes neutrophil dysplasia and blocks macrophage/dendritic cell development in mice. Blood 2012;119:4723-4730.
    • (2012) Blood , vol.119 , pp. 4723-4730
    • Alemdehy, M.F.1
  • 88
    • 84862908547 scopus 로고    scopus 로고
    • Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
    • Montecalvo A, et al. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood 2011;119:756-766.
    • (2011) Blood , vol.119 , pp. 756-766
    • Montecalvo, A.1
  • 89
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang KJ, Baltimore D. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 2006;103:12481-12486.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 90
    • 79251592866 scopus 로고    scopus 로고
    • Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling
    • Nahid MA, Satoh M, Chan EK. Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling. J Immunol 2010;186:1723-1734.
    • (2010) J Immunol , vol.186 , pp. 1723-1734
    • Nahid, M.A.1    Satoh, M.2    Chan, E.K.3
  • 91
    • 70349439320 scopus 로고    scopus 로고
    • miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses
    • Liu G, Friggeri A, Yang Y, Park YJ, Tsuruta Y, Abraham E. miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses. Proc Natl Acad Sci USA 2009;106:15819-15824.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 15819-15824
    • Liu, G.1    Friggeri, A.2    Yang, Y.3    Park, Y.J.4    Tsuruta, Y.5    Abraham, E.6
  • 92
    • 75649113377 scopus 로고    scopus 로고
    • Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
    • Sheedy FJ, et al. Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol 2010;11:141-147.
    • (2010) Nat Immunol , vol.11 , pp. 141-147
    • Sheedy, F.J.1
  • 93
    • 68649091506 scopus 로고    scopus 로고
    • The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs
    • Androulidaki A, et al. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity 2009;31:220-231.
    • (2009) Immunity , vol.31 , pp. 220-231
    • Androulidaki, A.1
  • 94
    • 78650645817 scopus 로고    scopus 로고
    • MicroRNA-148/152 impair innate response and antigen presentation of TLR-triggered dendritic cells by targeting CaMKIIalpha
    • Liu X, et al. MicroRNA-148/152 impair innate response and antigen presentation of TLR-triggered dendritic cells by targeting CaMKIIalpha. J Immunol 2010;185:7244-7251.
    • (2010) J Immunol , vol.185 , pp. 7244-7251
    • Liu, X.1
  • 95
    • 77954488963 scopus 로고    scopus 로고
    • miR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation
    • Jurkin J, et al. miR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation. J Immunol 2010;184:4955-4965.
    • (2010) J Immunol , vol.184 , pp. 4955-4965
    • Jurkin, J.1
  • 96
    • 38049030287 scopus 로고    scopus 로고
    • Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
    • Tili E, et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol 2007;179:5082-5089.
    • (2007) J Immunol , vol.179 , pp. 5082-5089
    • Tili, E.1
  • 97
    • 84862107170 scopus 로고    scopus 로고
    • Integrin CD11b negatively regulates TLR9-triggered dendritic cell cross-priming by upregulating microRNA-146a
    • Bai Y, et al. Integrin CD11b negatively regulates TLR9-triggered dendritic cell cross-priming by upregulating microRNA-146a. J Immunol 2012;188:5293-5302.
    • (2012) J Immunol , vol.188 , pp. 5293-5302
    • Bai, Y.1
  • 98
    • 84984765621 scopus 로고    scopus 로고
    • Canalization of development by microRNAs
    • Hornstein E, Shomron N. Canalization of development by microRNAs. Nat Genet 2006;38(Suppl):S20-S24.
    • (2006) Nat Genet , vol.38 , Issue.SUPPL.
    • Hornstein, E.1    Shomron, N.2
  • 99
    • 84867380174 scopus 로고    scopus 로고
    • microRNA-181a represses ox-LDL-stimulated inflammatory response in dendritic cell by targeting c-Fos
    • Wu C, et al. microRNA-181a represses ox-LDL-stimulated inflammatory response in dendritic cell by targeting c-Fos. J Lipid Res 2012;53:2355-2363.
    • (2012) J Lipid Res , vol.53 , pp. 2355-2363
    • Wu, C.1
  • 100
    • 84864279381 scopus 로고    scopus 로고
    • Inductive microRNA-21 impairs anti-mycobacterial responses by targeting IL-12 and Bcl-2
    • Wu Z, Lu H, Sheng J, Li L. Inductive microRNA-21 impairs anti-mycobacterial responses by targeting IL-12 and Bcl-2. FEBS Lett 2012;586:2459-2467.
    • (2012) FEBS Lett , vol.586 , pp. 2459-2467
    • Wu, Z.1    Lu, H.2    Sheng, J.3    Li, L.4
  • 101
    • 82755162151 scopus 로고    scopus 로고
    • Microbiota downregulates dendritic cell expression of miR-10a, which targets IL-12/IL-23p40
    • Xue X, et al. Microbiota downregulates dendritic cell expression of miR-10a, which targets IL-12/IL-23p40. J Immunol 2011;187:5879-5886.
    • (2011) J Immunol , vol.187 , pp. 5879-5886
    • Xue, X.1
  • 102
    • 79551475486 scopus 로고    scopus 로고
    • MicroRNA-146a regulates the maturation process and pro-inflammatory cytokine secretion by targeting CD40L in oxLDL-stimulated dendritic cells
    • Chen T, et al. MicroRNA-146a regulates the maturation process and pro-inflammatory cytokine secretion by targeting CD40L in oxLDL-stimulated dendritic cells. FEBS Lett 2011;585:567-573.
    • (2011) FEBS Lett , vol.585 , pp. 567-573
    • Chen, T.1
  • 103
    • 79951579619 scopus 로고    scopus 로고
    • MicroRNA-29a regulates pro-inflammatory cytokine secretion and scavenger receptor expression by targeting LPL in oxLDL-stimulated dendritic cells
    • Chen T, et al. MicroRNA-29a regulates pro-inflammatory cytokine secretion and scavenger receptor expression by targeting LPL in oxLDL-stimulated dendritic cells. FEBS Lett 2011;585:657-663.
    • (2011) FEBS Lett , vol.585 , pp. 657-663
    • Chen, T.1
  • 104
    • 77953411618 scopus 로고    scopus 로고
    • MicroRNA-466 l upregulates IL-10 expression in TLR-triggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation
    • Ma F, et al. MicroRNA-466 l upregulates IL-10 expression in TLR-triggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation. J Immunol 2010;184:6053-6059.
    • (2010) J Immunol , vol.184 , pp. 6053-6059
    • Ma, F.1
  • 105
    • 79951598704 scopus 로고    scopus 로고
    • Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk
    • Biton M, et al. Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk. Nat Immunol 2011;12:239-246.
    • (2011) Nat Immunol , vol.12 , pp. 239-246
    • Biton, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.