miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 36, 2010, Pages 15804-15809

  Mann, Mati ^a   Barad, Omer ^a   Agami, Reuven ^b   Geiger, Benjamin ^a   Hornstein, Eran ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Differentiation; Macrophage; microRNA; miR 155; Osteoclast

Indexed keywords

MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MICRORNA; OSTEOCLAST DIFFERENTIATION FACTOR; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TNFRSF11A PROTEIN, MOUSE; TNFSF11 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CONTROLLED STUDY; GENE EXPRESSION; MACROPHAGE; MONOCYTE; MULTIPOTENT STEM CELL; NONHUMAN; OSTEOCLASTOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CELL LINE; CELL LINEAGE; CYTOLOGY; METABOLISM; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; CELL LINE; CELL LINEAGE; MICE; MICRORNAS; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 77957664009     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0915022107     Document Type: Article

References (41)

1. Kawai T, Akira S (2007) TLR signaling. Semin Immunol 19:24-32.
2. Lacey DL, et al. (1998) Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93:165-176.
3. Yasuda H, et al. (1998) Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 95:3597-3602.
4. Boyle WJ, Simonet WS, Lacey DL (2003) Osteoclast differentiation and activation. Nature 423:337-342.
5. Cavaillon JM, Haeffner-Cavaillon N (1990) Signals involved in interleukin 1 synthesis and release by lipopolysaccharide-stimulated monocytes/macrophages. Cytokine 2:313-329.
6. Godambe SA, Chaplin DD, Bellone CJ (1993) Regulation of IL-1 gene expression: Differential responsiveness of murine macrophage lines. Cytokine 5:327-335.
7. Bogdan C (2001) Nitric oxide and the immune response. Nat Immunol 2:907-916.
8. Stark A, Brennecke J, Bushati N, Russell RB, Cohen SM (2005) Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3′UTR evolution. Cell 123:1133-1146.
9. Farh KK, et al. (2005) The widespread impact of mammalian MicroRNAs on mRNA repression and evolution. Science 310:1817-1821.
10. Yi R, Poy MN, Stoffel M, Fuchs E (2008) A skin microRNA promotes differentiation by repressing 'stemness'. Nature 452:225-229.
11. Giraldez AJ, et al. (2005) MicroRNAs regulate brain morphogenesis in zebrafish. Science 308:833-838.
12. Hornstein E, Shomron N (2006) Canalization of development by microRNAs. Nat Genet 38 (Suppl):S20-S24.
13. Sugatani T, Hruska KA (2009) Impaired micro-RNA pathways diminish osteoclast differentiation and function. J Biol Chem 284:4667-4678.
14. Tam W (2001) Identification and characterization of human BIC, a gene on chromosome 21 that encodes a noncoding RNA. Gene 274:157-167.
15. Teng G, Papavasiliou FN (2009) Shhh! Silencing by microRNA-155. Philos Trans R Soc Lond B Biol Sci 364:631-637.
16. O'Connell RM, Taganov KD, Boldin MP, Cheng G, Baltimore D (2007) MicroRNA-155 is induced during the macrophage inflammatory response. Proc Natl Acad Sci USA 104:1604-1609. (Pubitemid 46214637)
17. Tili E, et al. (2007) Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol 179:5082-5089.
18. O'Connell RM, et al. (2008) Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med 205:585-594.
19. Ruggiero T, et al. (2009) LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J 23:2898-2908.
20. Rodriguez A, et al. (2007) Requirement of bic/microRNA-155 for normal immune function. Science 316:608-611.
21. O'Connell RM, Chaudhuri AA, Rao DS, Baltimore D (2009) Inositol phosphatase SHIP1 is a primary target of miR-155. Proc Natl Acad Sci USA 106:7113-7118.
22. Raschke WC, Baird S, Ralph P, Nakoinz I (1978) Functional macrophage cell lines transformed by Abelson leukemia virus. Cell 15:261-267.
23. Hsu H, et al. (1999) Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci USA 96:3540-3545.
24. Krek A, et al. (2005) Combinatorial microRNA target predictions. Nat Genet 37:495-500.
25. Betel D, Wilson M, Gabow A, Marks DS, Sander C (2008) The microRNA.org resource: Targets and expression. Nucleic Acids Res 36 (Database issue):D149-D153.
26. Lewis BP, Burge CB, Bartel DP (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120:15-20.
27. Taganov KD, Boldin MP, Chang KJ, Baltimore D (2006) NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 103:12481-12486.
28. Sheng MH, Wergedal JE, Mohan S, Lau KH (2008) Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity. FEBS Lett 582:1451-1458.
29. Ripoll VM, et al. (2008) Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB. Gene 413:32-41.
30. Weilbaecher KN, et al. (2001) Linkage of M-CSF signaling to Mitf, TFE3, and the osteoclast defect in Mitf(mi/mi) mice. Mol Cell 8:749-758.
31. Meadows NA, et al. (2007) The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor. J Biol Chem 282:1891-1904.
32. Sharma SM, et al. (2007) MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation. J Biol Chem 282:15921-15929.
33. Gatto G, et al. (2008) Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-kappaB pathway. Nucleic Acids Res 36:6608-6619.
34. Ishii J, et al. (2008) Lipopolysaccharide suppresses RANK gene expression in macrophages by down-regulating PU.1 and MITF. J Cell Biochem 105:896-904.
35. Luchin A, et al. (2001) Genetic and physical interactions between Microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation. J Biol Chem 276:36703-36710. (Pubitemid 37384284)
36. Martinez-Nunez RT, Louafi F, Friedmann PS, Sanchez-Elsner T (2009) MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN). J Biol Chem 284:16334-16342.
37. Vigorito E, et al. (2007) microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity 27:847-859. (Pubitemid 350258623)
38. Hornstein E, et al. (2005) The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature 438:671-674.
39. Bartel DP (2009) MicroRNAs: Target recognition and regulatory functions. Cell 136:215-233.
40. Lu J, et al. (2008) MicroRNA-mediated control of cell fate in megakaryocyteerythrocyte progenitors. Dev Cell 14:843-853.
41. Stanczyk J, et al. (2008) Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum 58:1001-1009. (Pubitemid 351564001)