메뉴 건너뛰기




Volumn 2013, Issue 2, 2013, Pages

MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD150 ANTIGEN; CD45 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MICRORNA; MICRORNA 146A; MICRORNA 146B; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; MIRN146 MICRORNA, HUMAN;

EID: 84879060116     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.00537     Document Type: Article
Times cited : (110)

References (45)
  • 1
    • 61749100610 scopus 로고    scopus 로고
    • Risks of myeloid malignancies in patients with autoimmune conditions
    • doi: 10.1038/sj.bjc.6604935
    • Anderson LA, Pfeiffer RM, Landgren O, Gadalla S, Berndt SI, Engels EA. 2009. Risks of myeloid malignancies in patients with autoimmune conditions. Br J Cancer 100:822-8. doi: 10.1038/sj.bjc.6604935.
    • (2009) Br J Cancer , vol.100 , pp. 822-828
    • Anderson, L.A.1    Pfeiffer, R.M.2    Landgren, O.3    Gadalla, S.4    Berndt, S.I.5    Engels, E.A.6
  • 2
    • 77953462161 scopus 로고    scopus 로고
    • Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection
    • doi: 10.1038/nature09135
    • Baldridge MT, King KY, Boles NC, Weksberg DC, Goodell MA. 2010. Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature 465:793-7. doi: 10.1038/nature09135.
    • (2010) Nature , vol.465 , pp. 793-797
    • Baldridge, M.T.1    King, K.Y.2    Boles, N.C.3    Weksberg, D.C.4    Goodell, M.A.5
  • 3
    • 80051959463 scopus 로고    scopus 로고
    • NF-kappaB is 25
    • doi: 10.1038/ni.2072
    • Baltimore D. 2011. NF-kappaB is 25. Nat Immunol 12:683-5. doi: 10.1038/ni.2072.
    • (2011) Nat Immunol , vol.12 , pp. 683-685
    • Baltimore, D.1
  • 4
    • 77955658323 scopus 로고    scopus 로고
    • Stem cells and the aging hematopoietic system
    • doi: 10.1016/j.coi.2010.06.007
    • Beerman I, Maloney WJ, Weissmann IL, Rossi DJ. 2010. Stem cells and the aging hematopoietic system. Curr Opin Immunol 22:500-6. doi: 10.1016/j.coi.2010.06.007.
    • (2010) Curr Opin Immunol , vol.22 , pp. 500-506
    • Beerman, I.1    Maloney, W.J.2    Weissmann, I.L.3    Rossi, D.J.4
  • 5
    • 84858722006 scopus 로고    scopus 로고
    • MicroRNAs, new effectors and regulators of NF-kappaB
    • doi: 10.1111/j.1600-065X.2011.01089.x
    • Boldin MP, Baltimore D. 2012. MicroRNAs, new effectors and regulators of NF-kappaB. Immunol Rev 246:205-20. doi: 10.1111/j.1600-065X.2011.01089.x.
    • (2012) Immunol Rev , vol.246 , pp. 205-220
    • Boldin, M.P.1    Baltimore, D.2
  • 6
    • 79958257077 scopus 로고    scopus 로고
    • miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
    • doi: 10.1084/jem.20101823
    • Boldin MP, Taganov KD, Rao DS, Yang L, Zhao JL, Kalwani M, et al. 2011. miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J Exp Med 208:1189-201. doi: 10.1084/jem.20101823.
    • (2011) J Exp Med , vol.208 , pp. 1189-1201
    • Boldin, M.P.1    Taganov, K.D.2    Rao, D.S.3    Yang, L.4    Zhao, J.L.5    Kalwani, M.6
  • 7
    • 0025183151 scopus 로고
    • Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice
    • doi: 10.1172/JCI114749
    • Brandt SJ, Bodine DM, Dunbar CE, Nienhuis AW. 1990. Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. J Clin Invest 86:592-9. doi: 10.1172/JCI114749.
    • (1990) J Clin Invest , vol.86 , pp. 592-599
    • Brandt, S.J.1    Bodine, D.M.2    Dunbar, C.E.3    Nienhuis, A.W.4
  • 8
    • 79955530513 scopus 로고    scopus 로고
    • Chronic exposure to a TLR ligand injures hematopoietic stem cells
    • doi: 10.4049/jimmunol.1003438
    • Esplin BL, Shimazu T, Welner RS, Garrett KP, Nie L, Zhang Q, et al. 2011. Chronic exposure to a TLR ligand injures hematopoietic stem cells. J Immunol 186:5367-75. doi: 10.4049/jimmunol.1003438.
    • (2011) J Immunol , vol.186 , pp. 5367-5375
    • Esplin, B.L.1    Shimazu, T.2    Welner, R.S.3    Garrett, K.P.4    Nie, L.5    Zhang, Q.6
  • 9
    • 66149115277 scopus 로고    scopus 로고
    • IFNalpha activates dormant haematopoietic stem cells in vivo
    • doi: 10.1038/nature07815
    • Essers MA, Offner S, Blanco-Bose WE, Waibler Z, Kalinke U, Duchosal MA, et al. 2009. IFNalpha activates dormant haematopoietic stem cells in vivo. Nature 458:904-8. doi: 10.1038/nature07815.
    • (2009) Nature , vol.458 , pp. 904-908
    • Essers, M.A.1    Offner, S.2    Blanco-Bose, W.E.3    Waibler, Z.4    Kalinke, U.5    Duchosal, M.A.6
  • 10
    • 84861148197 scopus 로고    scopus 로고
    • Regulation of monocyte functional heterogeneity by miR-146a and Relb
    • doi: 10.1016/j.celrep.2012.02.009
    • Etzrodt M, Cortez-Retamozo V, Newton A, Zhao J, Ng A, Wildgruber M, et al. 2012. Regulation of monocyte functional heterogeneity by miR-146a and Relb. Cell Rep 1:317-24. doi: 10.1016/j.celrep.2012.02.009.
    • (2012) Cell Rep , vol.1 , pp. 317-324
    • Etzrodt, M.1    Cortez-Retamozo, V.2    Newton, A.3    Zhao, J.4    Ng, A.5    Wildgruber, M.6
  • 12
    • 33750467991 scopus 로고    scopus 로고
    • Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models
    • doi: 10.1038/sj.onc.1209944
    • Gerondakis S, Grumont R, Gugasyan R, Wong L, Isomura I, Ho W, et al. 2006. Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models. Oncogene 25:6781-99. doi: 10.1038/sj.onc.1209944.
    • (2006) Oncogene , vol.25 , pp. 6781-6799
    • Gerondakis, S.1    Grumont, R.2    Gugasyan, R.3    Wong, L.4    Isomura, I.5    Ho, W.6
  • 13
    • 58649108302 scopus 로고    scopus 로고
    • IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
    • doi: 10.1016/j.ccr.2009.01.001
    • Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S, et al. 2009. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 15:103-13. doi: 10.1016/j.ccr.2009.01.001.
    • (2009) Cancer Cell , vol.15 , pp. 103-113
    • Grivennikov, S.1    Karin, E.2    Terzic, J.3    Mucida, D.4    Yu, G.Y.5    Vallabhapurapu, S.6
  • 14
    • 77956270732 scopus 로고    scopus 로고
    • MicroRNA miR-125a controls hematopoietic stem cell number
    • doi: 10.1073/pnas.0913574107
    • Guo S, Lu J, Schlanger R, Zhang H, Wang JY, Fox MC, et al. 2010. MicroRNA miR-125a controls hematopoietic stem cell number. Proc Natl Acad Sci USA 107:14229-34. doi: 10.1073/pnas.0913574107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14229-14234
    • Guo, S.1    Lu, J.2    Schlanger, R.3    Zhang, H.4    Wang, J.Y.5    Fox, M.C.6
  • 15
    • 84859584516 scopus 로고    scopus 로고
    • Perspectives on chronic inflammation in essential thrombocythemia, polycythemia vera, and myelofibrosis: Is chronic inflammation a trigger and driver of clonal evolution and development of accelerated atherosclerosis and second cancer?
    • doi: 10.1182/blood-2011-11-394775
    • Hasselbalch HC. 2012. Perspectives on chronic inflammation in essential thrombocythemia, polycythemia vera, and myelofibrosis: is chronic inflammation a trigger and driver of clonal evolution and development of accelerated atherosclerosis and second cancer? Blood 119:3219-25. doi: 10.1182/blood-2011-11-394775.
    • (2012) Blood , vol.119 , pp. 3219-3225
    • Hasselbalch, H.C.1
  • 16
    • 0026672334 scopus 로고
    • Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus
    • doi: 10.1084/jem.176.4.1149
    • Hawley RG, Fong AZ, Burns BF, Hawley TS. 1992. Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus. J Exp Med 176:1149-63. doi: 10.1084/jem.176.4.1149.
    • (1992) J Exp Med , vol.176 , pp. 1149-1163
    • Hawley, R.G.1    Fong, A.Z.2    Burns, B.F.3    Hawley, T.S.4
  • 17
    • 70350778443 scopus 로고    scopus 로고
    • An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
    • doi: 10.1016/j.cell.2009.10.014
    • Iliopoulos D, Hirsch HA, Struhl K. 2009. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 139:693-706. doi: 10.1016/j.cell.2009.10.014.
    • (2009) Cell , vol.139 , pp. 693-706
    • Iliopoulos, D.1    Hirsch, H.A.2    Struhl, K.3
  • 18
    • 80053133049 scopus 로고    scopus 로고
    • Inflammatory modulation of HSCs: Viewing the HSC as a foundation for the immune response
    • doi: 10.1038/nri3062
    • King KY, Goodell MA. 2011. Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nat Rev Immunol 11:685-92. doi: 10.1038/nri3062.
    • (2011) Nat Rev Immunol , vol.11 , pp. 685-692
    • King, K.Y.1    Goodell, M.A.2
  • 19
    • 79960709287 scopus 로고    scopus 로고
    • Chronic immune stimulation might act as a trigger for the development of acute myeloid leukemia or myelodysplastic syndromes
    • doi: 10.1200/JCO.2011.34.8540
    • Kristinsson SY, Bjorkholm M, Hultcrantz M, Derolf AR, Landgren O, Goldin LR. 2011. Chronic immune stimulation might act as a trigger for the development of acute myeloid leukemia or myelodysplastic syndromes. J Clin Oncol 29:2897-903. doi: 10.1200/JCO.2011.34.8540.
    • (2011) J Clin Oncol , vol.29 , pp. 2897-2903
    • Kristinsson, S.Y.1    Bjorkholm, M.2    Hultcrantz, M.3    Derolf, A.R.4    Landgren, O.5    Goldin, L.R.6
  • 20
    • 0034730713 scopus 로고    scopus 로고
    • Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
    • doi: 10.1126/science.289.5488.2350
    • Lee EG, Boone DL, Chai S, Libby SL, Chien M, Lodolce JP, et al. 2000. Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice. Science 289:2350-4. doi: 10.1126/science.289.5488.2350.
    • (2000) Science , vol.289 , pp. 2350-2354
    • Lee, E.G.1    Boone, D.L.2    Chai, S.3    Libby, S.L.4    Chien, M.5    Lodolce, J.P.6
  • 21
    • 20644450804 scopus 로고    scopus 로고
    • Negative regulation of toll-like receptor-mediated immune responses
    • doi: 10.1038/nri1630
    • Liew FY, Xu D, Brint EK, O'Neill LA. 2005. Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol 5:446-58. doi: 10.1038/nri1630.
    • (2005) Nat Rev Immunol , vol.5 , pp. 446-458
    • Liew, F.Y.1    Xu, D.2    Brint, E.K.3    O'Neill, L.A.4
  • 22
    • 70449379193 scopus 로고    scopus 로고
    • Gnotobiotic IL-10; NF-kappaB mice develop rapid and severe colitis following Campylobacter jejuni infection
    • doi: 10.1371/journal.pone.0007413
    • Lippert E, Karrasch T, Sun X, Allard B, Herfarth HH, Threadgill D, et al. 2009. Gnotobiotic IL-10; NF-kappaB mice develop rapid and severe colitis following Campylobacter jejuni infection. PLoS One 4:e7413. doi: 10.1371/journal.pone.0007413.
    • (2009) PLoS One , vol.4
    • Lippert, E.1    Karrasch, T.2    Sun, X.3    Allard, B.4    Herfarth, H.H.5    Threadgill, D.6
  • 23
    • 77956632634 scopus 로고    scopus 로고
    • Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses
    • doi: 10.1016/j.cell.2010.08.012
    • Lu LF, Boldin MP, Chaudhry A, Lin LL, Taganov KD, Hanada T, et al. 2010. Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses. Cell 142:914-29. doi: 10.1016/j.cell.2010.08.012.
    • (2010) Cell , vol.142 , pp. 914-929
    • Lu, L.F.1    Boldin, M.P.2    Chaudhry, A.3    Lin, L.L.4    Taganov, K.D.5    Hanada, T.6
  • 24
    • 3242768987 scopus 로고    scopus 로고
    • In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse
    • Magness ST, Jijon H, Van Houten Fisher N, Sharpless NE, Brenner DA, Jobin C. 2004. In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse. J Immunol 173:1561-70.
    • (2004) J Immunol , vol.173 , pp. 1561-1570
    • Magness, S.T.1    Jijon, H.2    van Houten Fisher, N.3    Sharpless, N.E.4    Brenner, D.A.5    Jobin, C.6
  • 25
    • 84871647883 scopus 로고    scopus 로고
    • Flow cytometry analysis of murine hematopoietic stem cells
    • doi: 10.1002/cyto.a.22093
    • Mayle A, Luo M, Jeong M, Goodell MA. (2013). Flow cytometry analysis of murine hematopoietic stem cells. Cytometry A 83:27-37. doi: 10.1002/cyto.a.22093.
    • (2013) Cytometry A , vol.83 , pp. 27-37
    • Mayle, A.1    Luo, M.2    Jeong, M.3    Goodell, M.A.4
  • 26
    • 33744978765 scopus 로고    scopus 로고
    • Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment
    • doi: 10.1016/j.immuni.2006.04.008
    • Nagai Y, Garrett KP, Ohta S, Bahrun U, Kouro T, Akira S, et al. 2006. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity 24:801-12. doi: 10.1016/j.immuni.2006.04.008.
    • (2006) Immunity , vol.24 , pp. 801-812
    • Nagai, Y.1    Garrett, K.P.2    Ohta, S.3    Bahrun, U.4    Kouro, T.5    Akira, S.6
  • 27
    • 80052446462 scopus 로고    scopus 로고
    • MicroRNA in TLR signaling and endotoxin tolerance
    • doi: 10.1038/cmi.2011.26
    • Nahid MA, Satoh M, Chan EK. 2011. MicroRNA in TLR signaling and endotoxin tolerance. Cell Mol Immunol 8:388-403. doi: 10.1038/cmi.2011.26.
    • (2011) Cell Mol Immunol , vol.8 , pp. 388-403
    • Nahid, M.A.1    Satoh, M.2    Chan, E.K.3
  • 28
    • 40649109728 scopus 로고    scopus 로고
    • The wolf in sheep's clothing: The role of interleukin-6 in immunity, inflammation and cancer
    • doi: 10.1016/j.molmed.2007.12.007
    • Naugler WE, Karin M. 2008. The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer. Trends Mol Med 14:109-19. doi: 10.1016/j.molmed.2007.12.007.
    • (2008) Trends Mol Med , vol.14 , pp. 109-119
    • Naugler, W.E.1    Karin, M.2
  • 29
    • 67651171730 scopus 로고    scopus 로고
    • MDS: A stem cell disorder-but what exactly is wrong with the primitive hematopoietic cells in this disease?
    • doi: 10.1182/asheducation-2008.1.43
    • Nimer SD. 2008a. MDS: a stem cell disorder-but what exactly is wrong with the primitive hematopoietic cells in this disease?. Hematology Am Soc Hematol Educ Program 43-51. doi: 10.1182/asheducation-2008.1.43.
    • (2008) Hematology Am Soc Hematol Educ Program , pp. 43-51
    • Nimer, S.D.1
  • 30
    • 46749151451 scopus 로고    scopus 로고
    • Myelodysplastic syndromes
    • doi: 10.1182/blood-2007-08-078139
    • Nimer SD. 2008b. Myelodysplastic syndromes. Blood 111:4841-51. doi: 10.1182/blood-2007-08-078139.
    • (2008) Blood , vol.111 , pp. 4841-4851
    • Nimer, S.D.1
  • 31
    • 66349137358 scopus 로고    scopus 로고
    • Inositol phosphatase SHIP1 is a primary target of miR-155
    • doi: 10.1073/pnas.0902636106
    • O'Connell RM, Chaudhuri AA, Rao DS, Baltimore D. 2009. Inositol phosphatase SHIP1 is a primary target of miR-155. Proc Natl Acad Sci USA 106:7113-8. doi: 10.1073/pnas.0902636106.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7113-7118
    • O'Connell, R.M.1    Chaudhuri, A.A.2    Rao, D.S.3    Baltimore, D.4
  • 32
    • 77956288810 scopus 로고    scopus 로고
    • MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output
    • doi: 10.1073/pnas.1009798107
    • O'Connell RM, Chaudhuri AA, Rao DS, Gibson WS, Balazs AB, Baltimore D. 2010. MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output. Proc Natl Acad Sci USA 107:14235-40. doi: 10.1073/pnas.1009798107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14235-14240
    • O'Connell, R.M.1    Chaudhuri, A.A.2    Rao, D.S.3    Gibson, W.S.4    Balazs, A.B.5    Baltimore, D.6
  • 33
    • 57849159061 scopus 로고    scopus 로고
    • Toll-like receptors and cancer
    • doi: 10.1038/nrc2541
    • Rakoff-Nahoum S, Medzhitov R. 2009. Toll-like receptors and cancer. Nat Rev Cancer 9:57-63. doi: 10.1038/nrc2541.
    • (2009) Nat Rev Cancer , vol.9 , pp. 57-63
    • Rakoff-Nahoum, S.1    Medzhitov, R.2
  • 34
    • 81255189474 scopus 로고    scopus 로고
    • IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development
    • doi: 10.1016/j.ccr.2011.10.012
    • Reynaud D, Pietras E, Barry-Holson K, Mir A, Binnewies M, Jeanne M, et al. 2011. IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development. Cancer Cell 20:661-73. doi: 10.1016/j.ccr.2011.10.012.
    • (2011) Cancer Cell , vol.20 , pp. 661-673
    • Reynaud, D.1    Pietras, E.2    Barry-Holson, K.3    Mir, A.4    Binnewies, M.5    Jeanne, M.6
  • 35
    • 84856709581 scopus 로고    scopus 로고
    • Deregulation of microRNAs in myelodysplastic syndrome
    • doi: 10.1038/leu.2011.221
    • Rhyasen GW, Starczynowski DT. 2012. Deregulation of microRNAs in myelodysplastic syndrome. Leukemia 26:13-22. doi: 10.1038/leu.2011.221.
    • (2012) Leukemia , vol.26 , pp. 13-22
    • Rhyasen, G.W.1    Starczynowski, D.T.2
  • 36
    • 80051982064 scopus 로고    scopus 로고
    • Return to homeostasis: Downregulation of NF-kappaB responses
    • doi: 10.1038/ni.2055
    • Ruland J. 2011. Return to homeostasis: downregulation of NF-kappaB responses. Nat Immunol 12:709-14. doi: 10.1038/ni.2055.
    • (2011) Nat Immunol , vol.12 , pp. 709-714
    • Ruland, J.1
  • 37
    • 40949123149 scopus 로고    scopus 로고
    • Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
    • doi: 10.1016/j.arr.2007.09.002
    • Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T. 2008. Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res Rev 7:83-105. doi: 10.1016/j.arr.2007.09.002.
    • (2008) Ageing Res Rev , vol.7 , pp. 83-105
    • Salminen, A.1    Huuskonen, J.2    Ojala, J.3    Kauppinen, A.4    Kaarniranta, K.5    Suuronen, T.6
  • 38
    • 78751582939 scopus 로고    scopus 로고
    • Hematopoietic stem cell: Self-renewal versus differentiation
    • doi: 10.1002/wsbm.86
    • Seita J, Weissman IL. 2010. Hematopoietic stem cell: self-renewal versus differentiation. Wiley Interdiscip Rev Syst Biol Med 2:640-53. doi: 10.1002/wsbm.86.
    • (2010) Wiley Interdiscip Rev Syst Biol Med , vol.2 , pp. 640-653
    • Seita, J.1    Weissman, I.L.2
  • 39
    • 55749114037 scopus 로고    scopus 로고
    • Characteristics of US patients with myelodysplastic syndromes: Results of six cross-sectional physician surveys
    • doi: 10.1093/jnci/djn349
    • Sekeres MA, Schoonen WM, Kantarjian H, List A, Fryzek J, Paquette R, et al. 2008. Characteristics of US patients with myelodysplastic syndromes: results of six cross-sectional physician surveys. J Natl Cancer Inst 100:1542-51. doi: 10.1093/jnci/djn349.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1542-1551
    • Sekeres, M.A.1    Schoonen, W.M.2    Kantarjian, H.3    List, A.4    Fryzek, J.5    Paquette, R.6
  • 40
    • 73849121794 scopus 로고    scopus 로고
    • Identification of miR-145 and miR-146a as mediators of the 5q-syndrome phenotype
    • doi: 10.1038/nm.2054
    • Starczynowski DT, Kuchenbauer F, Argiropoulos B, Sung S, Morin R, Muranyi A, et al. 2010. Identification of miR-145 and miR-146a as mediators of the 5q-syndrome phenotype. Nat Med 16:49-58. doi: 10.1038/nm.2054.
    • (2010) Nat Med , vol.16 , pp. 49-58
    • Starczynowski, D.T.1    Kuchenbauer, F.2    Argiropoulos, B.3    Sung, S.4    Morin, R.5    Muranyi, A.6
  • 41
    • 84866354593 scopus 로고    scopus 로고
    • miR-146a controls the resolution of T cell responses in mice
    • doi: 10.1084/jem.20112218
    • Yang L, Boldin MP, Yu Y, Liu CS, Ea CK, Ramakrishnan P, et al. 2012. miR-146a controls the resolution of T cell responses in mice. J Exp Med 209:1655-70. doi: 10.1084/jem.20112218.
    • (2012) J Exp Med , vol.209 , pp. 1655-1670
    • Yang, L.1    Boldin, M.P.2    Yu, Y.3    Liu, C.S.4    Ea, C.K.5    Ramakrishnan, P.6
  • 42
    • 77957725130 scopus 로고    scopus 로고
    • STAT3 controls myeloid progenitor growth during emergency granulopoiesis
    • doi: 10.1182/blood-2009-12-259630
    • Zhang H, Nguyen-Jackson H, Panopoulos AD, Li HS, Murray PJ, Watowich SS. 2010. STAT3 controls myeloid progenitor growth during emergency granulopoiesis. Blood 116:2462-71. doi: 10.1182/blood-2009-12-259630.
    • (2010) Blood , vol.116 , pp. 2462-2471
    • Zhang, H.1    Nguyen-Jackson, H.2    Panopoulos, A.D.3    Li, H.S.4    Murray, P.J.5    Watowich, S.S.6
  • 43
    • 0032555932 scopus 로고    scopus 로고
    • Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein alpha (C/EBP alpha) is critical for granulopoiesis
    • doi: 10.1073/pnas.88.23.10638
    • Zhang P, Iwama A, Datta MW, Darlington GJ, Link DC, Tenen DG. 1998. Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein alpha (C/EBP alpha) is critical for granulopoiesis. J Exp Med 188:1173-84. doi: 10.1073/pnas.88.23.10638.
    • (1998) J Exp Med , vol.188 , pp. 1173-1184
    • Zhang, P.1    Iwama, A.2    Datta, M.W.3    Darlington, G.J.4    Link, D.C.5    Tenen, D.G.6
  • 44
    • 84859503920 scopus 로고    scopus 로고
    • Noncanonical NF-kappaB signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions
    • doi: 10.1002/stem.1050
    • Zhao C, Xiu Y, Ashton J, Xing L, Morita Y, Jordan CT, et al. 2012. Noncanonical NF-kappaB signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions. Stem Cells 30:709-18. doi: 10.1002/stem.1050.
    • (2012) Stem Cells , vol.30 , pp. 709-718
    • Zhao, C.1    Xiu, Y.2    Ashton, J.3    Xing, L.4    Morita, Y.5    Jordan, C.T.6
  • 45
    • 79959362128 scopus 로고    scopus 로고
    • NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies
    • doi: 10.1073/pnas.1105398108
    • Zhao JL, Rao DS, Boldin MP, Taganov KD, O'Connell RM, Baltimore D. 2011. NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies. Proc Natl Acad Sci USA 108:9184-9. doi: 10.1073/pnas.1105398108.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 9184-9189
    • Zhao, J.L.1    Rao, D.S.2    Boldin, M.P.3    Taganov, K.D.4    O'Connell, R.M.5    Baltimore, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.