-
1
-
-
0031020884
-
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
-
H. Tian, S. L. McKnight, and D. W. Russell, "Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells," Genes&Development, vol. 11, no. 1, pp. 72-82, 1997
-
(1997)
Genes&Development
, vol.11
, Issue.1
, pp. 72-82
-
-
Tian, H.1
McKnight, S.L.2
Russell, D.W.3
-
2
-
-
0031000736
-
A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1 regulates the VEGF expression and is potentially involved in lung and vascular development
-
M. Ema, S. Taya, N. Yokotani, K. Sogawa, Y. Matsuda, and Y. Fujii-Kuriyama, "A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1 regulates the VEGF expression and is potentially involved in lung and vascular development," Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 9, pp. 4273-4278, 1997
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.9
, pp. 4273-4278
-
-
Ema, M.1
Taya, S.2
Yokotani, N.3
Sogawa, K.4
Matsuda, Y.5
Fujii-Kuriyama, Y.6
-
3
-
-
0031733828
-
Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha
-
Y. Z. Gu, S. M. Moran, J. B. Hogenesch, L. Wartman, and C. A. Bradfield, "Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha," Gene Expression, vol. 7, no. 3, pp. 205-213, 1998
-
(1998)
Gene Expression
, vol.7
, Issue.3
, pp. 205-213
-
-
Gu, Y.Z.1
Moran, S.M.2
Hogenesch, J.B.3
Wartman, L.4
Bradfield, C.A.5
-
4
-
-
0033233243
-
Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
-
G. L. Semenza, "Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1," Annual Review of Cell and Developmental Biology, vol. 15, pp. 551-578, 1999
-
(1999)
Annual Review of Cell and Developmental Biology
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
5
-
-
0036828845
-
Leu-574 of HIF-1 is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway
-
L. E. Eric Huang, E. A. Pete, M. Schau, J. Milligan, and J. Gu, "Leu-574 of HIF-1 is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway," The Journal of Biological Chemistry, vol. 277, no. 44, pp. 41750-41755, 2002
-
(2002)
The Journal of Biological Chemistry
, vol.277
, Issue.44
, pp. 41750-41755
-
-
Eric Huang, L.E.1
Pete, E.A.2
Schau, M.3
Milligan, J.4
Gu, J.5
-
6
-
-
4043086934
-
Leu-574 of human HIF-1 is a molecular determinant of prolyl hydroxylation
-
Y. Kageyama,M. Koshiji,K. K. W. To, Y.-M. Tian, P. J. Ratcliffe, and L. E. Huang, "Leu-574 of human HIF-1 is a molecular determinant of prolyl hydroxylation," The FASEB Journal, vol. 18, no. 9, pp. 1028-1030, 2004
-
(2004)
The FASEB Journal
, vol.18
, Issue.9
, pp. 1028-1030
-
-
Kageyama, Y.1
Koshiji, M.2
To, K.K.W.3
Tian, Y.-M.4
Ratcliffe, P.J.5
Huang, L.E.6
-
7
-
-
0035903468
-
Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
-
N. Masson, C. Willam, P. H. Maxwell, C. W. Pugh, and P. J. Ratcliffe, "Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation," The EMBO Journal, vol. 20, no. 18, pp. 5197-5206, 2001
-
(2001)
The EMBO Journal
, vol.20
, Issue.18
, pp. 5197-5206
-
-
Masson, N.1
Willam, C.2
Maxwell, P.H.3
Pugh, C.W.4
Ratcliffe, P.J.5
-
8
-
-
41149115123
-
The role of oxygen availability in embryonic development and stem cell function
-
M. C. Simon and B. Keith, "The role of oxygen availability in embryonic development and stem cell function," Nature Reviews Molecular Cell Biology, vol. 9, no. 4, pp. 285-296, 2008
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.4
, pp. 285-296
-
-
Simon, M.C.1
Keith, B.2
-
9
-
-
0032538797
-
Signal transduction in hypoxic cells: Inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha
-
P. J. Kallio, K. Okamoto, S. O'Brien et al., "Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha," The EMBO Journal, vol. 17, no. 22, pp. 6573-6586, 1998
-
(1998)
The EMBO Journal
, vol.17
, Issue.22
, pp. 6573-6586
-
-
Kallio, P.J.1
Okamoto, K.2
O'brien, S.3
-
10
-
-
0030937718
-
Activation of hypoxia-inducible factor-1; Definition of regulatory domains within the subunit
-
C. W. Pugh, J. F. O'Rourke, M. Nagao, J. M. Gleadle, and P. J. Ratcliffe, "Activation of hypoxia-inducible factor-1; Definition of regulatory domains within the subunit," The Journal of Biological Chemistry, vol. 272, no. 17, pp. 11205-11214, 1997
-
(1997)
The Journal of Biological Chemistry
, vol.272
, Issue.17
, pp. 11205-11214
-
-
Pugh, C.W.1
O'rourke, J.F.2
Nagao, M.3
Gleadle, J.M.4
Ratcliffe, P.J.5
-
11
-
-
33947724515
-
HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells
-
R. Fukuda, H. Zhang, J. W. Kim, L. Shimoda, C. V. Dang, and G. Semenza, "HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells," Cell, vol. 129, no. 1, pp. 111-122, 2007
-
(2007)
Cell
, vol.129
, Issue.1
, pp. 111-122
-
-
Fukuda, R.1
Zhang, H.2
Kim, J.W.3
Shimoda, L.4
Dang, C.V.5
Semenza, G.6
-
12
-
-
9444283176
-
Differentiating the functional role of hypoxia-inducible factor (HIF)-1 and HIF-2 (EPAS-1) by the use of RNA interference: Erythropoietin is a HIF-2 target gene in Hep3B and Kelly cells
-
C. Warnecke, Z. Zaborowska, J. Kurreck et al., "Differentiating the functional role of hypoxia-inducible factor (HIF)-1 and HIF-2 (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2 target gene in Hep3B and Kelly cells," The FASEB Journal, vol. 18, no. 12, pp. 1462-1464, 2004
-
(2004)
The FASEB Journal
, vol.18
, Issue.12
, pp. 1462-1464
-
-
Warnecke, C.1
Zaborowska, Z.2
Kurreck, J.3
-
13
-
-
0345491599
-
Differential Roles of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in Hypoxic Gene Regulation
-
C.-J. Hu, L.-Y. Wang, L. A. Chodosh, B. Keith, and M. C. Simon, "Differential Roles of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in Hypoxic Gene Regulation," Molecular and Cellular Biology, vol. 23, no. 24, pp. 9361-9374, 2003
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.24
, pp. 9361-9374
-
-
Hu, C.-J.1
Wang, L.-Y.2
Chodosh, L.A.3
Keith, B.4
Simon, M.C.5
-
14
-
-
20744445650
-
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
-
R. R. Raval, K. W. Lau, M. G. B. Tran et al., "Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma," Molecular and Cellular Biology, vol. 25, no. 13, pp. 5675-5686, 2005
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.13
, pp. 5675-5686
-
-
Raval, R.R.1
Lau, K.W.2
Tran, M.G.B.3
-
15
-
-
33744954065
-
Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: The role of HIF-1, HIF-2, and other pathways
-
G. P. Elvidge, L. Glenny, R. J. Appelhoff, P. J. Ratcliffe, J. Ragoussis, and J. M. Gleadle, "Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1, HIF-2, and other pathways,"The Journal of Biological Chemistry, vol. 281, no. 22, pp. 15215-15226, 2006
-
(2006)
The Journal of Biological Chemistry
, vol.281
, Issue.22
, pp. 15215-15226
-
-
Elvidge, G.P.1
Glenny, L.2
Appelhoff, R.J.3
Ratcliffe, P.J.4
Ragoussis, J.5
Gleadle, J.M.6
-
16
-
-
0042704727
-
Hypoxia rapidly activatesHIF-3alphamRNA expression
-
M. Heidbreder, F. Fröhlich, O. Jöhren, A. Dendorfer, F. Qadri, and P. Dominiak, "Hypoxia rapidly activatesHIF-3alphamRNA expression," The FASEB Journal, vol. 17, no. 11, pp. 1541-1543, 2003
-
(2003)
The FASEB Journal
, vol.17
, Issue.11
, pp. 1541-1543
-
-
Heidbreder, M.1
Fröhlich, F.2
Jöhren, O.3
Dendorfer, A.4
Qadri, F.5
Dominiak, P.6
-
17
-
-
84870497082
-
Molecular, functional, and gene expression analysis of zebrafish hypoxia-inducible factor-3alpha
-
P. Zhang, L. Lu, Q. Yao et al., "Molecular, functional, and gene expression analysis of zebrafish hypoxia-inducible factor-3alpha," The American Journal of Physiology-Regulatory Integrative and Comparative Physiology, vol. 303, no. 11, pp. R1165-R1174, 2012
-
(2012)
The American Journal of Physiology-Regulatory Integrative and Comparative Physiology
, vol.303
, Issue.11
, pp. R1165-R1174
-
-
Zhang, P.1
Lu, L.2
Yao, Q.3
-
18
-
-
0037031808
-
Inhibitory PAS domain protein (IPAS) is a hypoxiainducible splicing variant of the hypoxia-inducible factor-3 locus
-
Y. Makino, A. Kanopka, W. J. Wilson, H. Tanaka, and L. Poellinger, "Inhibitory PAS domain protein (IPAS) is a hypoxiainducible splicing variant of the hypoxia-inducible factor-3 locus," The Journal of Biological Chemistry, vol. 277, no. 36, pp. 32405-32408, 2002
-
(2002)
The Journal of Biological Chemistry
, vol.277
, Issue.36
, pp. 32405-32408
-
-
Makino, Y.1
Kanopka, A.2
Wilson, W.J.3
Tanaka, H.4
Poellinger, L.5
-
19
-
-
33750630119
-
Recruitment of HIF-1 and HIF-2 to common target genes is differentially regulated in neuroblastoma: HIF-2 promotes an aggressive phenotype
-
L. Holmquist-Mengelbier, E. Fredlund, T. Löfstedt et al., "Recruitment of HIF-1 and HIF-2 to common target genes is differentially regulated in neuroblastoma: HIF-2 promotes an aggressive phenotype," Cancer Cell, vol. 10, no. 5, pp. 413-423, 2006
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 413-423
-
-
Holmquist-Mengelbier, L.1
Fredlund, E.2
Löfstedt, T.3
-
20
-
-
79957440998
-
The hypoxia-associated factor switches cells from HIF-1-to HIF-2-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion
-
M. Y. Koh, R. Lemos Jr., X. Liu, and G. Powis, "The hypoxia-associated factor switches cells from HIF-1-to HIF-2-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion," Cancer Research, vol. 71, no. 11, pp. 4015-4027, 2011
-
(2011)
Cancer Research
, vol.71
, Issue.11
, pp. 4015-4027
-
-
Koh, M.Y.1
Lemos, R.2
Liu, X.3
Powis, G.4
-
21
-
-
0035917808
-
Targeting of HIF- to the vonHippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
P. Jaakkola, D. R. Mole, Y.-M. Tian et al., "Targeting of HIF- to the vonHippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation," Science, vol. 292, no. 5516, pp. 468-472, 2001
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.-M.3
-
22
-
-
0035917313
-
HIF targeted for VHLmediated destruction by proline hydroxylation: Implications for O2 sensing
-
M. Ivan, K. Kondo, H. Yang et al., "HIF targeted for VHLmediated destruction by proline hydroxylation: implications for O2 sensing," Science, vol. 292, no. 5516, pp. 464-468, 2001
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
-
23
-
-
0032493368
-
Regulation of hypoxia-inducible factor 1 is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway
-
L. E. Huang, J. Gu, M. Schau, and H. F. Bunn, "Regulation of hypoxia-inducible factor 1 is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway," Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 14, pp. 7987-7992, 1998
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.14
, pp. 7987-7992
-
-
Huang, L.E.1
Gu, J.2
Schau, M.3
Bunn, H.F.4
-
24
-
-
17944375360
-
C. Elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
A. C. R. Epstein, J. M. Gleadle, L. A. McNeill et al., "C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation," Cell, vol. 107, no. 1, pp. 43-54, 2001
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 43-54
-
-
Epstein, A.C.R.1
Gleadle, J.M.2
McNeill, L.A.3
-
25
-
-
0041465022
-
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1 in normoxia
-
E. Berra, E. Benizri, A. Ginouvès, V. Volmat, D. Roux, and J. Pouysségur, "HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1 in normoxia," The EMBO Journal, vol. 22, no. 16, pp. 4082-4090, 2003
-
(2003)
The EMBO Journal
, vol.22
, Issue.16
, pp. 4082-4090
-
-
Berra, E.1
Benizri, E.2
Ginouvès, A.3
Volmat, V.4
Roux, D.5
Pouysségur, J.6
-
26
-
-
70449580319
-
Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization
-
K. Lee,H. Zhang,D. Z. Qian, S. Rey, J. O. Liu, and G. L. Semenza, "Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization," Proceedings of theNationalAcademy of Sciences of the United States of America, vol. 106, no. 42, pp. 17910-17915, 2009
-
(2009)
Proceedings of TheNationalAcademy of Sciences of the United States of America
, vol.106
, Issue.42
, pp. 17910-17915
-
-
Lee, K.1
Zhang, H.2
Qian, D.Z.3
Rey, S.4
Liu, J.O.5
Semenza, G.L.6
-
27
-
-
67649980040
-
Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases
-
R. Chowdhury, M. A. McDonough, J. Mecinovíc et al., "Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases," Structure, vol. 17, no. 7, pp. 981-989, 2009
-
(2009)
Structure
, vol.17
, Issue.7
, pp. 981-989
-
-
Chowdhury, R.1
McDonough, M.A.2
Mecinovíc, J.3
-
28
-
-
0036433394
-
Mammalian EGLN genes have distinct patterns of mRNA expression and regulation
-
M. E. Lieb, K. Menzies, M. C. Moschella, R. Ni, and M. B. Taubman, "Mammalian EGLN genes have distinct patterns of mRNA expression and regulation," Biochemistry and Cell Biology, vol. 80, no. 4, pp. 421-426, 2002
-
(2002)
Biochemistry and Cell Biology
, vol.80
, Issue.4
, pp. 421-426
-
-
Lieb, M.E.1
Menzies, K.2
Moschella, M.C.3
Ni, R.4
Taubman, M.B.5
-
29
-
-
38649143118
-
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
-
J. Aragonés, M. Schneider, K. van Geyte et al., "Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism," Nature Genetics, vol. 40, no. 2, pp. 170-180, 2008
-
(2008)
Nature Genetics
, vol.40
, Issue.2
, pp. 170-180
-
-
Aragonés, J.1
Schneider, M.2
Van Geyte, K.3
-
30
-
-
77449090208
-
Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury
-
e2-1154. e2
-
M. Schneider, K. van Geyte, P. Fraisl et al., "Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury," Gastroenterology, vol. 138, no. 3, pp. 1143. e2-1154. e2, 2010
-
(2010)
Gastroenterology
, vol.138
, Issue.3
, pp. 1143
-
-
Schneider, M.1
Van Geyte, K.2
Fraisl, P.3
-
31
-
-
33750976389
-
Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2
-
K. Takeda, V. C. Ho, H. Takeda, L.-J. Duan, A. Nagy, and G.-H. Fong, "Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2," Molecular and Cellular Biology, vol. 26, no. 22, pp. 8336-8346, 2006
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.22
, pp. 8336-8346
-
-
Takeda, K.1
Ho, V.C.2
Takeda, H.3
Duan, L.-J.4
Nagy, A.5
Fong, G.-H.6
-
32
-
-
34547905406
-
Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system
-
K. Takeda, A. Cowan, and G.-H. Fong, "Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system," Circulation, vol. 116, no. 7, pp. 774-781, 2007
-
(2007)
Circulation
, vol.116
, Issue.7
, pp. 774-781
-
-
Takeda, K.1
Cowan, A.2
Fong, G.-H.3
-
33
-
-
42449163874
-
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
-
Y. A. Minamishima, J. Moslehi, N. Bardeesy, D. Cullen, R. T. Bronson, and W. G. Kaelin Jr., "Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure," Blood, vol. 111, no. 6, pp. 3236-3244, 2008
-
(2008)
Blood
, vol.111
, Issue.6
, pp. 3236-3244
-
-
Minamishima, Y.A.1
Moslehi, J.2
Bardeesy, N.3
Cullen, D.4
Bronson, R.T.5
Kaelin, W.G.6
-
34
-
-
43249108443
-
Abnormal sympathoadrenal development and systemic hypotension in PHD3/ mice
-
T. Bishop, D. Gallagher, A. Pascual et al., "Abnormal sympathoadrenal development and systemic hypotension in PHD3/ mice," Molecular and Cellular Biology, vol. 28, no. 10, pp. 3386-3400, 2008
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.10
, pp. 3386-3400
-
-
Bishop, T.1
Gallagher, D.2
Pascual, A.3
-
35
-
-
84896350565
-
Targeted gene deletion of prolyl hydroxylase domain protein 3 triggers angiogenesis and preserves cardiac function by stabilizing hypoxia inducible factor 1 alpha following myocardial infarction
-
B. Oriowo, M. Thirunavukkarasu, V. Selvaraju et al., "Targeted gene deletion of prolyl hydroxylase domain protein 3 triggers angiogenesis and preserves cardiac function by stabilizing hypoxia inducible factor 1 alpha following myocardial infarction," Current Pharmaceutical Design, vol. 20, no. 9, pp. 1305-1310, 2014
-
(2014)
Current Pharmaceutical Design
, vol.20
, Issue.9
, pp. 1305-1310
-
-
Oriowo, B.1
Thirunavukkarasu, M.2
Selvaraju, V.3
-
36
-
-
0034458228
-
The NADPH oxidase of endothelial cells
-
B. M. Babior, "The NADPH oxidase of endothelial cells," IUBMB Life, vol. 50, no. 4-5, pp. 267-269, 2000
-
(2000)
IUBMB Life
, vol.50
, Issue.4-5
, pp. 267-269
-
-
Babior, B.M.1
-
37
-
-
0037082101
-
The neutrophil NADPH oxidase
-
B. M. Babior, J. D. Lambeth, and W. Nauseef, "The neutrophil NADPH oxidase," Archives of Biochemistry and Biophysics, vol. 397, no. 2, pp. 342-344, 2002
-
(2002)
Archives of Biochemistry and Biophysics
, vol.397
, Issue.2
, pp. 342-344
-
-
Babior, B.M.1
Lambeth, J.D.2
Nauseef, W.3
-
38
-
-
0026564816
-
Cytochrome P450: Progress and predictions
-
M. J. Coon, X. Ding, S. J. Pernecky, and A. D. N. Vaz, "Cytochrome P450: progress and predictions," The FASEB Journal, vol. 6, no. 2, pp. 669-673, 1992
-
(1992)
The FASEB Journal
, vol.6
, Issue.2
, pp. 669-673
-
-
Coon, M.J.1
Ding, X.2
Pernecky, S.J.3
Vaz, A.D.N.4
-
39
-
-
0025312326
-
Circulating xanthine oxidase: Potential mediator of ischemic injury
-
Y. Yokoyama, J. S. Beckman, T. K. Beckman et al., "Circulating xanthine oxidase: potential mediator of ischemic injury," American Journal of Physiology-Gastrointestinal and Liver Physiology, vol. 258, no. 4, pp. G564-G570, 1990
-
(1990)
American Journal of Physiology-Gastrointestinal and Liver Physiology
, vol.258
, Issue.4
, pp. G564-G570
-
-
Yokoyama, Y.1
Beckman, J.S.2
Beckman, T.K.3
-
40
-
-
0030969868
-
Superoxide production by the mitochondrial respiratory chain
-
J. F. Turrens, "Superoxide production by the mitochondrial respiratory chain," Bioscience Reports, vol. 17, no. 1, pp. 3-8, 1997
-
(1997)
Bioscience Reports
, vol.17
, Issue.1
, pp. 3-8
-
-
Turrens, J.F.1
-
41
-
-
0035929367
-
The site of production of superoxide radical in mitochondrial Complex i is not a bound ubisemiquinone but presumably iron-sulfur cluster N2
-
M. L. Genova, B. Ventura, G. Giuliano et al., "The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron-sulfur cluster N2," FEBS Letters, vol. 505, no. 3, pp. 364-368, 2001
-
(2001)
FEBS Letters
, vol.505
, Issue.3
, pp. 364-368
-
-
Genova, M.L.1
Ventura, B.2
Giuliano, G.3
-
42
-
-
0037564168
-
Oxygen dependence of mitochondrial nitric oxide synthase activity
-
S. Alvarez, L. B. Valdez, T. Zaobornyj, and A. Boveris, "Oxygen dependence of mitochondrial nitric oxide synthase activity," Biochemical and Biophysical Research Communications, vol. 305, no. 3, pp. 771-775, 2003
-
(2003)
Biochemical and Biophysical Research Communications
, vol.305
, Issue.3
, pp. 771-775
-
-
Alvarez, S.1
Valdez, L.B.2
Zaobornyj, T.3
Boveris, A.4
-
43
-
-
0037158626
-
O2 sensing in hypoxic pulmonary vasoconstriction: Themitochondrial door re-opens
-
G. B. Waypa and P. T. Schumacker, "O2 sensing in hypoxic pulmonary vasoconstriction: themitochondrial door re-opens," Respiratory Physiology and Neurobiology, vol. 132, no. 1, pp. 81-91, 2002
-
(2002)
Respiratory Physiology and Neurobiology
, vol.132
, Issue.1
, pp. 81-91
-
-
Waypa, G.B.1
Schumacker, P.T.2
-
44
-
-
0036838355
-
Hypoxia, anoxia, and O2 sensing: The search continues
-
P. T. Schumacker, "Hypoxia, anoxia, and O2 sensing: the search continues," The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 283, no. 5, pp. L918-L921, 2002
-
(2002)
The American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.283
, Issue.5
, pp. L918-L921
-
-
Schumacker, P.T.1
-
45
-
-
0032578458
-
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
-
N. S. Chandel, E. Maltepe, E. Goldwasser, C. E. Mathieu, M. C. Simon, and P. T. Schumacker, "Mitochondrial reactive oxygen species trigger hypoxia-induced transcription," Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 20, pp. 11715-11720, 1998
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.20
, pp. 11715-11720
-
-
Chandel, N.S.1
Maltepe, E.2
Goldwasser, E.3
Mathieu, C.E.4
Simon, M.C.5
Schumacker, P.T.6
-
46
-
-
0036838358
-
Hypoxic but not anoxic stabilization of HIF-1 requires mitochondrial reactive oxygen species
-
C. Schroedl, D. S. McClintock, G. R. S. Budinger, and N. S. Chandel, "Hypoxic but not anoxic stabilization of HIF-1 requires mitochondrial reactive oxygen species," The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 283, no. 5, pp. L922-L931, 2002
-
(2002)
The American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.283
, Issue.5
, pp. L922-L931
-
-
Schroedl, C.1
McClintock, D.S.2
Budinger, G.R.S.3
Chandel, N.S.4
-
47
-
-
0034680825
-
The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia
-
F. H. Agani, P. Pichiule, J. C. Chavez, and J. C. LaManna, "The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia," The Journal of Biological Chemistry, vol. 275, no. 46, pp. 35863-35867, 2000
-
(2000)
The Journal of Biological Chemistry
, vol.275
, Issue.46
, pp. 35863-35867
-
-
Agani, F.H.1
Pichiule, P.2
Chavez, J.C.3
Lamanna, J.C.4
-
48
-
-
84875472017
-
The role of free radicals in the aging brain and Parkinson's disease: Convergence and parallelism
-
H. Kumar, H. W. Lim, S. V. More et al., "The role of free radicals in the aging brain and Parkinson's disease: convergence and parallelism," International Journal of Molecular Sciences, vol. 13, no. 8, pp. 10478-10504, 2012
-
(2012)
International Journal of Molecular Sciences
, vol.13
, Issue.8
, pp. 10478-10504
-
-
Kumar, H.1
Lim, H.W.2
More, S.V.3
-
49
-
-
84926511751
-
Mitochondrial signaling in hypoxia
-
L. D. Lukyanova, "Mitochondrial signaling in hypoxia," Open Journal of Endocrine and Metabolic Diseases, vol. 3, no. 2, pp. 20-32, 2013
-
(2013)
Open Journal of Endocrine and Metabolic Diseases
, vol.3
, Issue.2
, pp. 20-32
-
-
Lukyanova, L.D.1
-
50
-
-
24144447915
-
Mitochondrial dysfunction resulting fromloss of cytochrome c impairs cellular oxygen sensing and hypoxicHIF- Activation
-
K. D. Mansfield, R. D. Guzy, Y. Pan et al., "Mitochondrial dysfunction resulting fromloss of cytochrome c impairs cellular oxygen sensing and hypoxicHIF- Activation," CellMetabolism, vol. 1, no. 6, pp. 393-399, 2005
-
(2005)
CellMetabolism
, vol.1
, Issue.6
, pp. 393-399
-
-
Mansfield, K.D.1
Guzy, R.D.2
Pan, Y.3
-
51
-
-
24144493814
-
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
-
R. D. Guzy, B. Hoyos, E. Robin et al., "Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing," Cell Metabolism, vol. 1, no. 6, pp. 401-408, 2005
-
(2005)
Cell Metabolism
, vol.1
, Issue.6
, pp. 401-408
-
-
Guzy, R.D.1
Hoyos, B.2
Robin, E.3
-
52
-
-
0034682786
-
Reactive oxygen species generated at mitochondrial Complex III stabilize hypoxia-inducible factor-1 during hypoxia: A mechanism of O2 sensing
-
N. S. Chandel, D. S. McClintock, C. E. Feliciano et al., "Reactive oxygen species generated at mitochondrial Complex III stabilize hypoxia-inducible factor-1 during hypoxia: a mechanism of O2 sensing," The Journal of Biological Chemistry, vol. 275, no. 33, pp. 25130-25138, 2000
-
(2000)
The Journal of Biological Chemistry
, vol.275
, Issue.33
, pp. 25130-25138
-
-
Chandel, N.S.1
McClintock, D.S.2
Feliciano, C.E.3
-
53
-
-
34250745912
-
The site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production
-
E. L. Bell, T. A. Klimova, J. Eisenbart et al., "The site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production," The Journal of Cell Biology, vol. 177, no. 6, pp. 1029-1036, 2007
-
(2007)
The Journal of Cell Biology
, vol.177
, Issue.6
, pp. 1029-1036
-
-
Bell, E.L.1
Klimova, T.A.2
Eisenbart, J.3
-
54
-
-
0034282388
-
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1 in vascular smooth muscle cells
-
D. E. Richard, E. Berra, and J. Pouyssegur, "Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1 in vascular smooth muscle cells," The Journal of Biological Chemistry, vol. 275, no. 35, pp. 26765-26771, 2000
-
(2000)
The Journal of Biological Chemistry
, vol.275
, Issue.35
, pp. 26765-26771
-
-
Richard, D.E.1
Berra, E.2
Pouyssegur, J.3
-
55
-
-
0033562569
-
Defective vascularization of HIF-1-null embryos is not associated with VEGF deficiency but with mesenchymal cell death
-
L. E. Kotch, N. V. Iyer, E. Laughner, and G. L. Semenza, "Defective vascularization of HIF-1-null embryos is not associated with VEGF deficiency but with mesenchymal cell death," Developmental Biology, vol. 209, no. 2, pp. 254-267, 1999
-
(1999)
Developmental Biology
, vol.209
, Issue.2
, pp. 254-267
-
-
Kotch, L.E.1
Iyer, N.V.2
Laughner, E.3
Semenza, G.L.4
-
56
-
-
0032213236
-
The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
-
H. Tian, R. E. Hammer, A. M. Matsumoto, D. W. Russell, and S. L. McKnight, "The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development," Genes and Development, vol. 12, no. 21, pp. 3320-3324, 1998
-
(1998)
Genes and Development
, vol.12
, Issue.21
, pp. 3320-3324
-
-
Tian, H.1
Hammer, R.E.2
Matsumoto, A.M.3
Russell, D.W.4
McKnight, S.L.5
-
57
-
-
0035159670
-
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
-
D. M. Stroka, T. Burkhardt, I. Desbaillets et al., "HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia," The FASEB Journal, vol. 15, no. 13, pp. 2445-2453, 2001
-
(2001)
The FASEB Journal
, vol.15
, Issue.13
, pp. 2445-2453
-
-
Stroka, D.M.1
Burkhardt, T.2
Desbaillets, I.3
-
58
-
-
0034682513
-
The transcription factor EPAS-1/hypoxia-inducible factor 2 plays an important role in vascular remodeling
-
J. Peng, L. Zhang, L. Drysdale, and G.-H. Fong, "The transcription factor EPAS-1/hypoxia-inducible factor 2 plays an important role in vascular remodeling," Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 15, pp. 8386-8391, 2000
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.15
, pp. 8386-8391
-
-
Peng, J.1
Zhang, L.2
Drysdale, L.3
Fong, G.-H.4
-
59
-
-
0035914436
-
Hypoxia-inducible factor-2 (HIF-2) is involved in the apoptotic response to hypoglycemia but not to hypoxia
-
K. Brusselmans, F. Bono, P. Maxwell et al., "Hypoxia-inducible factor-2 (HIF-2) is involved in the apoptotic response to hypoglycemia but not to hypoxia," The Journal of Biological Chemistry, vol. 276, no. 42, pp. 39192-39196, 2001
-
(2001)
The Journal of Biological Chemistry
, vol.276
, Issue.42
, pp. 39192-39196
-
-
Brusselmans, K.1
Bono, F.2
Maxwell, P.3
-
60
-
-
0035203884
-
Hypoxia affects expression of circadian genes PER1 and CLOCK in mouse brain
-
D. Chilov, T. Hofer, C. Bauer, R. H. Wenger, and M. Gassmann, "Hypoxia affects expression of circadian genes PER1 and CLOCK in mouse brain," The FASEB Journal, vol. 15, no. 14, pp. 2613-2622, 2001
-
(2001)
The FASEB Journal
, vol.15
, Issue.14
, pp. 2613-2622
-
-
Chilov, D.1
Hofer, T.2
Bauer, C.3
Wenger, R.H.4
Gassmann, M.5
-
61
-
-
0036162264
-
Isoform-specific expression of hypoxia-inducible factor-1alpha during the late stages ofmouse spermiogenesis
-
H. H. Marti, D. M. Katschinski, K. F. Wagner, L. Schäffer, B. Stier, and R. H. Wenger, "Isoform-specific expression of hypoxia-inducible factor-1alpha during the late stages ofmouse spermiogenesis," Molecular Endocrinology, vol. 16, no. 2, pp. 234-243, 2002
-
(2002)
Molecular Endocrinology
, vol.16
, Issue.2
, pp. 234-243
-
-
Marti, H.H.1
Katschinski, D.M.2
Wagner, K.F.3
Schäffer, L.4
Stier, B.5
Wenger, R.H.6
-
62
-
-
0035966119
-
Differential Regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1alpha in activated T lymphocytes
-
D. Lukashev, C. Caldwell, A. Ohta, P. Chen, and M. Sitkovsky, "Differential Regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1alpha in activated T lymphocytes," The Journal of Biological Chemistry, vol. 276, no. 52, pp. 48754-48763, 2001
-
(2001)
The Journal of Biological Chemistry
, vol.276
, Issue.52
, pp. 48754-48763
-
-
Lukashev, D.1
Caldwell, C.2
Ohta, A.3
Chen, P.4
Sitkovsky, M.5
-
63
-
-
0037088576
-
Heat induction of the unphosphorylated form of hypoxia-inducible factor-1alpha is dependent on heat shock protein-90 activity
-
D. M. Katschinski, L. Le, D. Heinrich et al., "Heat induction of the unphosphorylated form of hypoxia-inducible factor-1alpha is dependent on heat shock protein-90 activity," Journal of Biological Chemistry, vol. 277, no. 11, pp. 9262-9267, 2002
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.11
, pp. 9262-9267
-
-
Katschinski, D.M.1
Le, L.2
Heinrich, D.3
-
64
-
-
84898052710
-
Low-dose radiation exposure induces a HIF-1-mediated adaptive and protective metabolic response
-
R. Lall, S. Ganapathy, M. Yang et al., "Low-dose radiation exposure induces a HIF-1-mediated adaptive and protective metabolic response," Cell Death and Differentiation, vol. 21, no. 5, pp. 836-844, 2014
-
(2014)
Cell Death and Differentiation
, vol.21
, Issue.5
, pp. 836-844
-
-
Lall, R.1
Ganapathy, S.2
Yang, M.3
-
65
-
-
84901373499
-
The role of the HIF-1 transcription factor in increased cell division at physiological oxygen tensions
-
S. Carrera, J. Senra, M. I. Acosta et al., "The role of the HIF-1 transcription factor in increased cell division at physiological oxygen tensions," PLoS ONE, vol. 9, no. 5, Article ID e97938, 2014
-
(2014)
PLoS ONE
, vol.9
, Issue.5
-
-
Carrera, S.1
Senra, J.2
Acosta, M.I.3
-
66
-
-
0013199207
-
Early expression ofmyocardialHIF-1 in response to mechanical stresses: Regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway
-
C.-H. Kim, Y.-S. Cho, Y.-S. Chun, J.-W. Park, and M.-S. Kim, "Early expression ofmyocardialHIF-1 in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway," Circulation Research, vol. 90, no. 2, pp. e25-e33, 2002
-
(2002)
Circulation Research
, vol.90
, Issue.2
, pp. e25-e33
-
-
Kim, C.-H.1
Cho, Y.-S.2
Chun, Y.-S.3
Park, J.-W.4
Kim, M.-S.5
-
67
-
-
15444342958
-
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1
-
N. V. Iyer, L. E. Kotch, F. Agani et al., "Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1," Genes and Development, vol. 12, no. 2, pp. 149-162, 1998
-
(1998)
Genes and Development
, vol.12
, Issue.2
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
-
68
-
-
0032100732
-
HIF-1 is required for solid tumor formation and embryonic vascularization
-
H. E. Ryan, J. Lo, and R. S. Johnson, "HIF-1 is required for solid tumor formation and embryonic vascularization," The EMBO Journal, vol. 17, no. 11, pp. 3005-3015, 1998
-
(1998)
The EMBO Journal
, vol.17
, Issue.11
, pp. 3005-3015
-
-
Ryan, H.E.1
Lo, J.2
Johnson, R.S.3
-
69
-
-
84917736664
-
Moderate hypoxia potentiates interleukin-1beta production in activated human macrophages
-
E. J. Folco, G. K. Sukhova, T. Quillard, and P. Libby, "Moderate hypoxia potentiates interleukin-1beta production in activated human macrophages," Circulation Research, vol. 115, no. 10, pp. 875-883, 2014
-
(2014)
Circulation Research
, vol.115
, Issue.10
, pp. 875-883
-
-
Folco, E.J.1
Sukhova, G.K.2
Quillard, T.3
Libby, P.4
-
70
-
-
0033104847
-
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1
-
A. Y. Yu, L. A. Shimoda,N. V. Iyer et al., "Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1," The Journal of Clinical Investigation, vol. 103, no. 5, pp. 691-696, 1999
-
(1999)
The Journal of Clinical Investigation
, vol.103
, Issue.5
, pp. 691-696
-
-
Yu, A.Y.1
Shimoda, L.A.2
Iyer, N.V.3
-
71
-
-
0034815688
-
Partial HIF-1 deficiency impairs pulmonary arterialmyocyte electrophysiological responses to hypoxia
-
L. A. Shimoda, D. J. Manalo, J. S. K. Sham, G. L. Semenza, and J. T. Sylvester, "Partial HIF-1 deficiency impairs pulmonary arterialmyocyte electrophysiological responses to hypoxia,"The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 281, no. 1, pp. L202-L208, 2001
-
(2001)
The American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.281
, Issue.1
, pp. L202-L208
-
-
Shimoda, L.A.1
Manalo, D.J.2
Sham, J.S.K.3
Semenza, G.L.4
Sylvester, J.T.5
-
72
-
-
22044436344
-
Developmental changes in HIF transcription factor in carotid body: Relevance for O2 sensing by chemoreceptors
-
J.-C. Roux, H. Brismar, A. Aperia, and H. Lagercrantz, "Developmental changes in HIF transcription factor in carotid body: relevance for O2 sensing by chemoreceptors," Pediatric Research, vol. 58, no. 1, pp. 53-57, 2005
-
(2005)
Pediatric Research
, vol.58
, Issue.1
, pp. 53-57
-
-
Roux, J.-C.1
Brismar, H.2
Aperia, A.3
Lagercrantz, H.4
-
73
-
-
0037154262
-
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1
-
D. D. Kline, Y.-J. Peng, D. J. Manalo, G. L. Semenza, and N. R. Prabhakar, "Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1," Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 2, pp. 821-826, 2002
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.2
, pp. 821-826
-
-
Kline, D.D.1
Peng, Y.-J.2
Manalo, D.J.3
Semenza, G.L.4
Prabhakar, N.R.5
-
74
-
-
79952609061
-
Hypoxia-inducible factor 2 (HIF-2) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
-
Y.-J. Peng, J. Nanduri, S. A. Khan et al., "Hypoxia-inducible factor 2 (HIF-2) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension," Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 7, pp. 3065-3070, 2011
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.7
, pp. 3065-3070
-
-
Peng, Y.-J.1
Nanduri, J.2
Khan, S.A.3
-
75
-
-
84877347155
-
Mutual antagonism between hypoxia-inducible factors 1 and 2 regulates oxygen sensing and cardio-respiratory homeostasis
-
G. Yuan, Y.-J. Peng, V. D. Reddy et al., "Mutual antagonism between hypoxia-inducible factors 1 and 2 regulates oxygen sensing and cardio-respiratory homeostasis," Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 19, pp. E1788-E1796, 2013
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, Issue.19
, pp. E1788-E1796
-
-
Yuan, G.1
Peng, Y.-J.2
Reddy, V.D.3
-
76
-
-
0035499204
-
Hypoxia in cartilage: HIF-1 is essential for chondrocyte growth arrest and survival
-
E. Schipani,H. E. Ryan, S. Didrickson, T. Kobayashi,M. Knight, and R. S. Johnson, "Hypoxia in cartilage: HIF-1 is essential for chondrocyte growth arrest and survival," Genes&Development, vol. 15, no. 21, pp. 2865-2876, 2001
-
(2001)
Genes&Development
, vol.15
, Issue.21
, pp. 2865-2876
-
-
Schipani, E.1
Ryan, H.E.2
Didrickson, S.3
Kobayashi, T.4
Knight, M.5
Johnson, R.S.6
-
77
-
-
0030879909
-
Regulation of human placental development by oxygen tension
-
O. Genbacev,Y. Zhou, J. W. Ludlow, and S. J. Fisher, "Regulation of human placental development by oxygen tension," Science, vol. 277, no. 5332, pp. 1669-1672, 1997
-
(1997)
Science
, vol.277
, Issue.5332
, pp. 1669-1672
-
-
Genbacev, O.1
Zhou, Y.2
Ludlow, J.W.3
Fisher, S.J.4
-
78
-
-
0034671706
-
Placental cell fates are regulated in vivo by HIFmediated hypoxia responses
-
D. M. Adelman, M. Gertsenstein, A. Nagy, M. C. Simon, and E. Maltepe, "Placental cell fates are regulated in vivo by HIFmediated hypoxia responses," Genes and Development, vol. 14, no. 24, pp. 3191-3203, 2000
-
(2000)
Genes and Development
, vol.14
, Issue.24
, pp. 3191-3203
-
-
Adelman, D.M.1
Gertsenstein, M.2
Nagy, A.3
Simon, M.C.4
Maltepe, E.5
-
79
-
-
24344502368
-
Hypoxiainducible factor-dependent histone deacetylase activity determines stem cell fate in the placenta
-
E. Maltepe, G. W. Krampitz, K. M. Okazaki et al., "Hypoxiainducible factor-dependent histone deacetylase activity determines stem cell fate in the placenta," Development, vol. 132, no. 15, pp. 3393-3403, 2005
-
(2005)
Development
, vol.132
, Issue.15
, pp. 3393-3403
-
-
Maltepe, E.1
Krampitz, G.W.2
Okazaki, K.M.3
-
80
-
-
0034100836
-
Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGF3
-
I. Caniggia, H. Mostachfi, J. Winter et al., "Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGF3," Journal of Clinical Investigation, vol. 105, no. 5, pp. 577-587, 2000
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.5
, pp. 577-587
-
-
Caniggia, I.1
Mostachfi, H.2
Winter, J.3
-
81
-
-
0036511366
-
Physiologically low oxygen concentrations in fetal skin regulate hypoxia-inducible factor 1 and transforming growth factor-beta3
-
A. Scheid, R. H. Wenger, L. Schäffer et al., "Physiologically low oxygen concentrations in fetal skin regulate hypoxia-inducible factor 1 and transforming growth factor-beta3," The FASEB Journal, vol. 16, no. 3, pp. 411-413, 2002
-
(2002)
The FASEB Journal
, vol.16
, Issue.3
, pp. 411-413
-
-
Scheid, A.1
Wenger, R.H.2
Schäffer, L.3
-
82
-
-
79957510410
-
A central role for hypoxic signaling in cartilage, bone, and hematopoiesis
-
E. B. Rankin, A. J. Giaccia, and E. Schipani, "A central role for hypoxic signaling in cartilage, bone, and hematopoiesis," Current Osteoporosis Reports, vol. 9, no. 2, pp. 46-52, 2011
-
(2011)
Current Osteoporosis Reports
, vol.9
, Issue.2
, pp. 46-52
-
-
Rankin, E.B.1
Giaccia, A.J.2
Schipani, E.3
-
83
-
-
70349758284
-
Hypoxia-inducible factor 1alpha inhibits the fibroblast-like markers type i and type III collagen during hypoxia-induced chondrocyte redifferentiation: Hypoxia not only induces type II collagen and aggrecan, but it also inhibits type i and type III collagen in the hypoxia-inducible factor 1alpha-dependent redifferentiation of chondrocytes
-
E. Duval, S. Leclercq, J.-M. Elissalde, M. Demoor, P. Galéra, and K. Boumédiene, "Hypoxia-inducible factor 1alpha inhibits the fibroblast-like markers type I and type III collagen during hypoxia-induced chondrocyte redifferentiation: hypoxia not only induces type II collagen and aggrecan, but it also inhibits type I and type III collagen in the hypoxia-inducible factor 1alpha-dependent redifferentiation of chondrocytes," Arthritis and Rheumatism, vol. 60, no. 10, pp. 3038-3048, 2009
-
(2009)
Arthritis and Rheumatism
, vol.60
, Issue.10
, pp. 3038-3048
-
-
Duval, E.1
Leclercq, S.2
Elissalde, J.-M.3
Demoor, M.4
Galéra, P.5
Boumédiene, K.6
-
84
-
-
34248532510
-
HIF-1 regulation of chondrocyte apoptosis: Induction of the autophagic pathway
-
J. Bohensky, I. M. Shapiro, S. Leshinsky, S. P. Terkhorn, C. S. Adams, and V. Srinivas, "HIF-1 regulation of chondrocyte apoptosis: induction of the autophagic pathway," Autophagy, vol. 3, no. 3, pp. 207-214, 2007
-
(2007)
Autophagy
, vol.3
, Issue.3
, pp. 207-214
-
-
Bohensky, J.1
Shapiro, I.M.2
Leshinsky, S.3
Terkhorn, S.P.4
Adams, C.S.5
Srinivas, V.6
-
85
-
-
77953208836
-
Transcriptional regulation of endochondral ossification by HIF-2 during skeletal growth and osteoarthritis development
-
T. Saito, A. Fukai, A. Mabuchi et al., "Transcriptional regulation of endochondral ossification by HIF-2 during skeletal growth and osteoarthritis development," Nature Medicine, vol. 16, no. 6, pp. 678-686, 2010
-
(2010)
Nature Medicine
, vol.16
, Issue.6
, pp. 678-686
-
-
Saito, T.1
Fukai, A.2
Mabuchi, A.3
-
86
-
-
77953183739
-
Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction
-
S. Yang, J. Kim, J. H. Ryu et al., "Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction," Nature Medicine, vol. 16, no. 6, pp. 687-693, 2010
-
(2010)
Nature Medicine
, vol.16
, Issue.6
, pp. 687-693
-
-
Yang, S.1
Kim, J.2
Ryu, J.H.3
-
87
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
I. Papandreou, R. A. Cairns, L. Fontana, A. L. Lim, and N. C. Denko, "HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption," Cell Metabolism, vol. 3, no. 3, pp. 187-197, 2006
-
(2006)
Cell Metabolism
, vol.3
, Issue.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
88
-
-
0029942862
-
The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2. 8 A
-
T. Tsukihara, H. Aoyama, E. Yamashita et al., "The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2. 8 A," Science, vol. 272, no. 5265, pp. 1136-1144, 1996
-
(1996)
Science
, vol.272
, Issue.5265
, pp. 1136-1144
-
-
Tsukihara, T.1
Aoyama, H.2
Yamashita, E.3
-
89
-
-
0032104133
-
Assembly of cytochrome-c oxidase in cultured human cells
-
L. G. J. Nijtmans, J.-W. Taanman, A. O. Muijsers, D. Speijer, and C. van den Bogert, "Assembly of cytochrome-c oxidase in cultured human cells," European Journal of Biochemistry, vol. 254, no. 2, pp. 389-394, 1998
-
(1998)
European Journal of Biochemistry
, vol.254
, Issue.2
, pp. 389-394
-
-
Nijtmans, L.G.J.1
Taanman, J.-W.2
Muijsers, A.O.3
Speijer, D.4
Bogert Den C.Van5
-
90
-
-
0031924141
-
Extramitochondrial ATP/ADP-ratios regulate cytochrome c oxidase activity via binding to the cytosolic domain of subunit IV
-
J. Napiwotzki and B. Kadenbach, "Extramitochondrial ATP/ADP-ratios regulate cytochrome c oxidase activity via binding to the cytosolic domain of subunit IV," Biological Chemistry, vol. 379, no. 3, pp. 335-339, 1998
-
(1998)
Biological Chemistry
, vol.379
, Issue.3
, pp. 335-339
-
-
Napiwotzki, J.1
Kadenbach, B.2
-
91
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptivemetabolic response to hypoxia
-
H. Zhang, M. Bosch-Marce, L. A. Shimoda et al., "Mitochondrial autophagy is an HIF-1-dependent adaptivemetabolic response to hypoxia," Journal of Biological Chemistry, vol. 283, no. 16, pp. 10892-10903, 2008
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.16
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
-
92
-
-
0015239454
-
The turnover of mitochondria in a variety of tissues of young adult and aged rats
-
R. A. Menzies and P. H. Gold, "The turnover of mitochondria in a variety of tissues of young adult and aged rats," The Journal of Biological Chemistry, vol. 246, no. 8, pp. 2425-2429, 1971
-
(1971)
The Journal of Biological Chemistry
, vol.246
, Issue.8
, pp. 2425-2429
-
-
Menzies, R.A.1
Gold, P.H.2
-
93
-
-
1842583789
-
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
-
B. Levine and D. J. Klionsky, "Development by self-digestion: molecular mechanisms and biological functions of autophagy," Developmental Cell, vol. 6, no. 4, pp. 463-477, 2004
-
(2004)
Developmental Cell
, vol.6
, Issue.4
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
94
-
-
27644575235
-
Macroautophagy versus mitochondrial autophagy: A question of fate
-
M. Kundu and C. B. Thompson, "Macroautophagy versus mitochondrial autophagy: a question of fate" Cell Death & Differentiation, vol. 12, supplement 2, pp. 1484-1489, 2005
-
(2005)
Cell Death & Differentiation
, vol.12
, pp. 1484-1489
-
-
Kundu, M.1
Thompson, C.B.2
-
96
-
-
34447133404
-
Cardiac autophagy is a maladaptive response to hemodynamic stress
-
H. Zhu, P. Tannous, J. L. Johnstone et al., "Cardiac autophagy is a maladaptive response to hemodynamic stress," The Journal of Clinical Investigation, vol. 117, no. 7, pp. 1782-1793, 2007
-
(2007)
The Journal of Clinical Investigation
, vol.117
, Issue.7
, pp. 1782-1793
-
-
Zhu, H.1
Tannous, P.2
Johnstone, J.L.3
-
97
-
-
0018827202
-
Lysosomal alterations in hypoxic and reoxygenated hearts. I. Ultrastructural and cytochemical changes
-
R. S. Decker and K. Wildenthal, "Lysosomal alterations in hypoxic and reoxygenated hearts. I. Ultrastructural and cytochemical changes," The American Journal of Pathology, vol. 98, no. 2, pp. 425-444, 1980
-
(1980)
The American Journal of Pathology
, vol.98
, Issue.2
, pp. 425-444
-
-
Decker, R.S.1
Wildenthal, K.2
-
98
-
-
33845511362
-
Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy
-
A. Hamacher-Brady, N. R. Brady, S. E. Logue et al., "Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy," Cell Death & Differentiation, vol. 14, no. 1, pp. 146-157, 2007
-
(2007)
Cell Death & Differentiation
, vol.14
, Issue.1
, pp. 146-157
-
-
Hamacher-Brady, A.1
Brady, N.R.2
Logue, S.E.3
-
99
-
-
0034255036
-
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
-
R. K. Bruick, "Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia," Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 16, pp. 9082-9087, 2000
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.16
, pp. 9082-9087
-
-
Bruick, R.K.1
-
100
-
-
0033566693
-
Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2
-
D. Feldser, F. Agani, N. V. Iyer, B. Pak, G. Ferreira, and G. L. Semenza, "Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2," Cancer Research, vol. 59, no. 16, pp. 3915-3918, 1999
-
(1999)
Cancer Research
, vol.59
, Issue.16
, pp. 3915-3918
-
-
Feldser, D.1
Agani, F.2
Iyer, N.V.3
Pak, B.4
Ferreira, G.5
Semenza, G.L.6
-
101
-
-
34248998801
-
Functional and physical interaction between Bcl-X and a BH3-like domain in Beclin-1
-
M. C. Maiuri, G. Le Toumelin, A. Criollo et al., "Functional and physical interaction between Bcl-X and a BH3-like domain in Beclin-1," The EMBO Journal, vol. 26, no. 10, pp. 2527-2539, 2007
-
(2007)
The EMBO Journal
, vol.26
, Issue.10
, pp. 2527-2539
-
-
Maiuri, M.C.1
Le Toumelin, G.2
Criollo, A.3
-
102
-
-
0038185378
-
Genomic targets of the human c-Myc protein
-
P. C. Fernandez, S. R. Frank, L. Wang et al., "Genomic targets of the human c-Myc protein," Genes and Development, vol. 17, no. 9, pp. 1115-1129, 2003
-
(2003)
Genes and Development
, vol.17
, Issue.9
, pp. 1115-1129
-
-
Fernandez, P.C.1
Frank, S.R.2
Wang, L.3
-
103
-
-
0038492517
-
A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells
-
Z. Li, S. van Calcar, C. Qu, W. K. Cavenee, M. Q. Zhang, and B. Ren, "A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells," Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 14, pp. 8164-8169, 2003
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.14
, pp. 8164-8169
-
-
Li, Z.1
Van Calcar, S.2
Qu, C.3
Cavenee, W.K.4
Zhang, M.Q.5
Ren, B.6
-
104
-
-
34247614521
-
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
-
H. Zhang, P. Gao, R. Fukuda et al., "HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity," Cancer Cell, vol. 11, no. 5, pp. 407-420, 2007
-
(2007)
Cancer Cell
, vol.11
, Issue.5
, pp. 407-420
-
-
Zhang, H.1
Gao, P.2
Fukuda, R.3
-
105
-
-
34547580590
-
HIF and c-Myc: Sibling rivals for control of cancer cell metabolism and proliferation
-
J. D. Gordan, C. B. Thompson, and M. C. Simon, "HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation," Cancer Cell, vol. 12, no. 2, pp. 108-113, 2007
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 108-113
-
-
Gordan, J.D.1
Thompson, C.B.2
Simon, M.C.3
-
106
-
-
37549032776
-
The interplay between MYC and HIF in cancer
-
C. V. Dang, J.-W. Kim, P. Gao, and J. Yustein, "The interplay between MYC and HIF in cancer," Nature Reviews Cancer, vol. 8, no. 1, pp. 51-56, 2008
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.1
, pp. 51-56
-
-
Dang, C.V.1
Kim, J.-W.2
Gao, P.3
Yustein, J.4
-
107
-
-
0032581277
-
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
P. Carmeliet, Y. Dor, J. M. Herbert et al., "Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis," Nature, vol. 394, pp. 485-490, 1998
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
-
108
-
-
0035418621
-
Constitutive expression of hypoxia-inducible factor-l renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation
-
N. Akakura, M. Kobayashi, I. Horiuchi et al., "Constitutive expression of hypoxia-inducible factor-l renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation," Cancer Research, vol. 61, no. 17, pp. 6548-6554, 2001
-
(2001)
Cancer Research
, vol.61
, Issue.17
, pp. 6548-6554
-
-
Akakura, N.1
Kobayashi, M.2
Horiuchi, I.3
-
109
-
-
0036082689
-
Anoxia-induced apoptosis occurs through a mitochondria-dependent pathway in lung epithelial cells
-
M. T. Santore, D. S. McClintock, V. Y. Lee, G. R. S. Budinger, and N. S. Chandel, "Anoxia-induced apoptosis occurs through a mitochondria-dependent pathway in lung epithelial cells," American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 282, no. 4, pp. L727-L734, 2002
-
(2002)
American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.282
, Issue.4
, pp. L727-L734
-
-
Santore, M.T.1
McClintock, D.S.2
Lee, V.Y.3
Budinger, G.R.S.4
Chandel, N.S.5
-
110
-
-
0036006511
-
Bc1-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death
-
D. S. McClintock, M. T. Santore, V. Y. Lee et al., "Bc1-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death,"Molecular and Cellular Biology, vol. 22, no. 1, pp. 94-104, 2002
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.1
, pp. 94-104
-
-
McClintock, D.S.1
Santore, M.T.2
Lee, V.Y.3
-
111
-
-
0032585644
-
Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury
-
P. Saikumar, Z. Dong, Y. Patel et al., "Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury," Oncogene, vol. 17, no. 26, pp. 3401-3415, 1998
-
(1998)
Oncogene
, vol.17
, Issue.26
, pp. 3401-3415
-
-
Saikumar, P.1
Dong, Z.2
Patel, Y.3
-
112
-
-
0035957653
-
ProapoptoticBAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
M. C. Wei,W. X. Zong, E. H. Y. Cheng et al., "ProapoptoticBAX and BAK: a requisite gateway to mitochondrial dysfunction and death," Science, vol. 292, no. 5517, pp. 727-730, 2001
-
(2001)
Science
, vol.292
, Issue.5517
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.Y.3
-
113
-
-
0028950645
-
Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL
-
S. Shimizu, Y. Eguchi, H. Kosaka,W. Kamiike, H. Matsuda, and Y. Tsujimoto, "Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL," Nature, vol. 374, no. 6525, pp. 811-813, 1995
-
(1995)
Nature
, vol.374
, Issue.6525
, pp. 811-813
-
-
Shimizu, S.1
Eguchi, Y.2
Kosaka, H.3
Kamiike, W.4
Matsuda, H.5
Tsujimoto, Y.6
-
114
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
T. G. Graeber, C. Osmanian, T. Jacks et al., "Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours," Nature, vol. 379, pp. 88-91, 1996
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
-
115
-
-
0037072937
-
An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome -independent activation of caspase-9 by caspase-12
-
N. Morishima, K. Nakanishi, H. Takenouchi, T. Shibata, and Y. Yasuhiko, "An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome -independent activation of caspase-9 by caspase-12," The Journal of Biological Chemistry, vol. 277, no. 37, pp. 34287-34294, 2002
-
(2002)
The Journal of Biological Chemistry
, vol.277
, Issue.37
, pp. 34287-34294
-
-
Morishima, N.1
Nakanishi, K.2
Takenouchi, H.3
Shibata, T.4
Yasuhiko, Y.5
-
116
-
-
0032411879
-
Stress signals for apoptosis: Ceramide and c-Jun kinase
-
S. Basu and R. Kolesnick, "Stress signals for apoptosis: ceramide and c-Jun kinase," Oncogene, vol. 17, no. 25, pp. 3277-3285, 1998
-
(1998)
Oncogene
, vol.17
, Issue.25
, pp. 3277-3285
-
-
Basu, S.1
Kolesnick, R.2
-
117
-
-
0142120661
-
Hypoxia-inducible factors 1 and 2 are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin
-
A. Giatromanolaki, E. Sivridis, C. Kouskoukis, K. C. Gatter, A. L. Harris, and M. I. Koukourakis, "Hypoxia-inducible factors 1 and 2 are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin," Melanoma Research, vol. 13,no. 5, pp. 493-501,2003
-
(2003)
Melanoma Research
, vol.13
, Issue.5
, pp. 493-501
-
-
Giatromanolaki, A.1
Sivridis, E.2
Kouskoukis, C.3
Gatter, K.C.4
Harris, A.L.5
Koukourakis, M.I.6
-
118
-
-
84877101126
-
HIF1 and HIF2 independently activate SRC to promote melanoma metastases
-
S. C. Hanna, B. Krishnan, S. T. Bailey et al., "HIF1 and HIF2 independently activate SRC to promote melanoma metastases," Journal of Clinical Investigation, vol. 123, no. 5, pp. 2078-2093, 2013
-
(2013)
Journal of Clinical Investigation
, vol.123
, Issue.5
, pp. 2078-2093
-
-
Hanna, S.C.1
Krishnan, B.2
Bailey, S.T.3
-
119
-
-
79952760563
-
VEGF as a biomarker for metastatic uveal melanoma in humans
-
V. Barak, J. Pe'er, I. Kalickman, and S. Frenkel, "VEGF as a biomarker for metastatic uveal melanoma in humans," Current Eye Research, vol. 36, no. 4, pp. 386-390, 2011
-
(2011)
Current Eye Research
, vol.36
, Issue.4
, pp. 386-390
-
-
Barak, V.1
Pe'er, J.2
Kalickman, I.3
Frenkel, S.4
-
120
-
-
33747873394
-
Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas
-
A. Giatromanolaki, E. Sivridis, C. Simopoulos et al., "Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas," Journal of Surgical Oncology, vol. 94, no. 3, pp. 242-247, 2006
-
(2006)
Journal of Surgical Oncology
, vol.94
, Issue.3
, pp. 242-247
-
-
Giatromanolaki, A.1
Sivridis, E.2
Simopoulos, C.3
-
121
-
-
0037617447
-
Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through Hypoxia-inducible factor
-
M. Baba, S. Hirai, H. Yamada-Okabe et al., "Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through Hypoxia-inducible factor," Oncogene, vol. 22, no. 18, pp. 2728-2738, 2003
-
(2003)
Oncogene
, vol.22
, Issue.18
, pp. 2728-2738
-
-
Baba, M.1
Hirai, S.2
Yamada-Okabe, H.3
-
122
-
-
3142631736
-
HIF-1 induces cell cycle arrest by functionally counteracting Myc
-
M. Koshiji, Y. Kageyama, E. A. Pete, I. Horikawa, J. C. Barrett, and L. E. Huang, "HIF-1 induces cell cycle arrest by functionally counteracting Myc," The EMBO Journal, vol. 23, no. 9, pp. 1949-1956, 2004
-
(2004)
The EMBO Journal
, vol.23
, Issue.9
, pp. 1949-1956
-
-
Koshiji, M.1
Kageyama, Y.2
Pete, E.A.3
Horikawa, I.4
Barrett, J.C.5
Huang, L.E.6
-
123
-
-
0025083389
-
Cerebral energy metabolism and intracellular pH during severe hypoxia and recovery: A study using 1H, 31P, and 1H [13C] nuclear magnetic resonance spectroscopy in the guinea pig cerebral cortex in vitro
-
R. A. Kauppinen and S. R. Williams, "Cerebral energy metabolism and intracellular pH during severe hypoxia and recovery: a study using 1H, 31P, and 1H [13C] nuclear magnetic resonance spectroscopy in the guinea pig cerebral cortex in vitro," Journal of Neuroscience Research, vol. 26, no. 3, pp. 356-369, 1990
-
(1990)
Journal of Neuroscience Research
, vol.26
, Issue.3
, pp. 356-369
-
-
Kauppinen, R.A.1
Williams, S.R.2
-
124
-
-
0031689058
-
Effect of hypoxic exposure on Na+/H+ antiport activity, isoform expression, and localization in endothelial cells
-
M. V. Cutaia,N. Parks, J. Centracchio, S. Rounds,K. P. Yip, and A. M. Sun, "Effect of hypoxic exposure on Na+/H+ antiport activity, isoform expression, and localization in endothelial cells," American Journal of Physiology: Lung Cellular and Molecular Physiology, vol. 275, no. 3, pp. L442-L451, 1998
-
(1998)
American Journal of Physiology: Lung Cellular and Molecular Physiology
, vol.275
, Issue.3
, pp. L442-L451
-
-
Cutaia, M.V.1
Parks, N.2
Centracchio, J.3
Rounds, S.4
Yip, K.P.5
Sun, A.M.6
-
125
-
-
0036174658
-
The changing face of the Na+/H+ exchanger, NHE1: Structure, regulation, and cellular actions
-
L. K. Putney, S. P. Denker, and D. L. Barber, "The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions," Annual Review of Pharmacology and Toxicology, vol. 42, pp. 527-552, 2002
-
(2002)
Annual Review of Pharmacology and Toxicology
, vol.42
, pp. 527-552
-
-
Putney, L.K.1
Denker, S.P.2
Barber, D.L.3
-
126
-
-
0030077602
-
The role of Na+/H+ exchange and growth factors in pulmonary artery smooth muscle cell proliferation
-
D. A. Quinn, C. G. W. Dahlberg, J. P. Bonventre et al., "The role of Na+/H+ exchange and growth factors in pulmonary artery smooth muscle cell proliferation," The American Journal of Respiratory Cell and Molecular Biology, vol. 14, no. 2, pp. 139-145, 1996
-
(1996)
The American Journal of Respiratory Cell and Molecular Biology
, vol.14
, Issue.2
, pp. 139-145
-
-
Quinn, D.A.1
Dahlberg, C.G.W.2
Bonventre, J.P.3
-
127
-
-
0032414861
-
Effects of hypoxia on energy state and pH in resting pulmonary and femoral arterial smooth muscles
-
R. M. Leach, D. W. Sheehan, V. P. Chacko, and J. T. Sylvester, "Effects of hypoxia on energy state and pH in resting pulmonary and femoral arterial smooth muscles," The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 275, no. 6, pp. L1051-L1060, 1998
-
(1998)
The American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.275
, Issue.6
, pp. L1051-L1060
-
-
Leach, R.M.1
Sheehan, D.W.2
Chacko, V.P.3
Sylvester, J.T.4
-
128
-
-
0034058481
-
Energy state, pH, and vasomotor tone during hypoxia in precontracted pulmonary and femoral arteries
-
R. M. Leach, D. W. Sheehan, V. P. Chacko, and J. T. Sylvester, "Energy state, pH, and vasomotor tone during hypoxia in precontracted pulmonary and femoral arteries," The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 278, no. 2, pp. L294-L304, 2000
-
(2000)
The American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.278
, Issue.2
, pp. L294-L304
-
-
Leach, R.M.1
Sheehan, D.W.2
Chacko, V.P.3
Sylvester, J.T.4
-
129
-
-
27144433158
-
Chronic hypoxia elevates intracellular pH and activates Na+/H+ exchange in pulmonary arterial smoothmuscle cells
-
E. J. Rios, M. Fallon, J. Wang, and L. A. Shimoda, "Chronic hypoxia elevates intracellular pH and activates Na+/H+ exchange in pulmonary arterial smoothmuscle cells," American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 289, no. 5, pp. L867-L874, 2005
-
(2005)
American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.289
, Issue.5
, pp. L867-L874
-
-
Rios, E.J.1
Fallon, M.2
Wang, J.3
Shimoda, L.A.4
-
130
-
-
33751117499
-
HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes
-
L. A. Shimoda, M. Fallon, S. Pisarcik, J. Wang, and G. L. Semenza, "HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes," American Journal of Physiology: Lung Cellular and Molecular Physiology, vol. 291, no. 5, pp. L941-L949, 2006
-
(2006)
American Journal of Physiology: Lung Cellular and Molecular Physiology
, vol.291
, Issue.5
, pp. L941-L949
-
-
Shimoda, L.A.1
Fallon, M.2
Pisarcik, S.3
Wang, J.4
Semenza, G.L.5
-
131
-
-
1242283850
-
Involvement of Na+/H+ exchanger in hypoxia/re-oxygenation-induced neonatal rat cardiomyocyte apoptosis
-
H.-Y. Sun, N.-P. Wang, M. E. Halkos et al., "Involvement of Na+/H+ exchanger in hypoxia/re-oxygenation-induced neonatal rat cardiomyocyte apoptosis," European Journal of Pharmacology, vol. 486, no. 2, pp. 121-131, 2004
-
(2004)
European Journal of Pharmacology
, vol.486
, Issue.2
, pp. 121-131
-
-
Sun, H.-Y.1
Wang, N.-P.2
Halkos, M.E.3
-
132
-
-
0033986761
-
Causes and consequences of tumour acidity and implications for treatment
-
M. Stubbs, P. M. J. McSheehy, J. R. Griffiths, and C. L. Bashford, "Causes and consequences of tumour acidity and implications for treatment,"MolecularMedicine Today, vol. 6, no. 1, pp. 15-19, 2000
-
(2000)
MolecularMedicine Today
, vol.6
, Issue.1
, pp. 15-19
-
-
Stubbs, M.1
McSheehy, P.M.J.2
Griffiths, J.R.3
Bashford, C.L.4
-
133
-
-
0035881307
-
Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo
-
D. Fukumura, L. Xu, Y. Chen, T. Gohongi, B. Seed, and R. K. Jain, "Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo," Cancer Research, vol. 61, no. 16, pp. 6020-6024, 2001
-
(2001)
Cancer Research
, vol.61
, Issue.16
, pp. 6020-6024
-
-
Fukumura, D.1
Xu, L.2
Chen, Y.3
Gohongi, T.4
Seed, B.5
Jain, R.K.6
-
134
-
-
8844249356
-
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH
-
E. Svastová, A. Hulíková, M. Rafajová et al., "Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH," FEBS Letters, vol. 577, no. 3, pp. 439-445, 2004
-
(2004)
FEBS Letters
, vol.577
, Issue.3
, pp. 439-445
-
-
Svastová, E.1
Hulková, A.2
Rafajová, M.3
-
135
-
-
58249094845
-
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
-
J. Chiche, K. Ilc, J. Laferrière et al., "Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH," Cancer Research, vol. 69, no. 1, pp. 358-368, 2009
-
(2009)
Cancer Research
, vol.69
, Issue.1
, pp. 358-368
-
-
Chiche, J.1
Ilc, K.2
Laferrière, J.3
-
136
-
-
84905259548
-
Negative regulation of HIF in skeletal muscle of elite endurance athletes: A tentative mechanism promoting oxidative metabolism
-
M. E. Lindholm, H. Fischer, L. Poellinger et al., "Negative regulation of HIF in skeletal muscle of elite endurance athletes: a tentative mechanism promoting oxidative metabolism," The American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, vol. 307, no. 3, pp. R248-R255, 2014
-
(2014)
The American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
, vol.307
, Issue.3
, pp. R248-R255
-
-
Lindholm, M.E.1
Fischer, H.2
Poellinger, L.3
-
137
-
-
0016888751
-
Biochemical adaptations to endurance exercise inmuscle
-
J. O. Holloszy and F. W. Booth, "Biochemical adaptations to endurance exercise inmuscle,"Annual Reviewof Physiology, vol. 38, pp. 273-291, 1976
-
(1976)
Annual Reviewof Physiology
, vol.38
, pp. 273-291
-
-
Holloszy, J.O.1
Booth, F.W.2
-
138
-
-
0021354398
-
Adaptive response of mammalian skeletal muscle to exercise with high loads
-
M. J. N. McDonagh and C. T. M. Davies, "Adaptive response of mammalian skeletal muscle to exercise with high loads," European Journal of Applied Physiology and Occupational Physiology, vol. 52, no. 2, pp. 139-155, 1984
-
(1984)
European Journal of Applied Physiology and Occupational Physiology
, vol.52
, Issue.2
, pp. 139-155
-
-
McDonagh, M.J.N.1
Davies, C.T.M.2
-
139
-
-
85003441266
-
Effects of systemic hypoxia on humanmuscular adaptations to resistance exercise training
-
M. Kon, N. Ohiwa, A. Honda et al., "Effects of systemic hypoxia on humanmuscular adaptations to resistance exercise training," Physiological Reports, vol. 2, no. 6,Article ID e12033, 2014
-
(2014)
Physiological Reports
, vol.2
, Issue.6
-
-
Kon, M.1
Ohiwa, N.2
Honda, A.3
-
140
-
-
33745756977
-
Endothelin-1, vascular endothelial growth factor and systolic pulmonary artery pressure in patients with Chuvash polycythemia
-
V. I. Bushuev, G. Y. Miasnikova, A. I. Sergueeva et al., "Endothelin-1, vascular endothelial growth factor and systolic pulmonary artery pressure in patients with Chuvash polycythemia," Haematologica, vol. 91, no. 6, pp. 744-749, 2006
-
(2006)
Haematologica
, vol.91
, Issue.6
, pp. 744-749
-
-
Bushuev, V.I.1
Miasnikova, G.Y.2
Sergueeva, A.I.3
-
141
-
-
18744373593
-
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
-
S. O. Ang, H. Chen, K. Hirota et al., "Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia," Nature Genetics, vol. 32, no. 4, pp. 614-621, 2002
-
(2002)
Nature Genetics
, vol.32
, Issue.4
, pp. 614-621
-
-
Ang, S.O.1
Chen, H.2
Hirota, K.3
-
142
-
-
77955456405
-
Regulation of human metabolism by hypoxia-inducible factor
-
F. Formenti, D. Constantin-Teodosiu, Y. Emmanuel et al., "Regulation of human metabolism by hypoxia-inducible factor," Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 28, pp. 12722-12727, 2010
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.28
, pp. 12722-12727
-
-
Formenti, F.1
Constantin-Teodosiu, D.2
Emmanuel, Y.3
-
143
-
-
80054960235
-
Effect of hypoxiainducible factor-1 gene therapy on walking performance in patients with intermittent claudication
-
M. A. Creager, J. W. Olin, J. J. F. Belch et al., "Effect of hypoxiainducible factor-1 gene therapy on walking performance in patients with intermittent claudication," Circulation, vol. 124, no. 16, pp. 1765-1773, 2011
-
(2011)
Circulation
, vol.124
, Issue.16
, pp. 1765-1773
-
-
Creager, M.A.1
Olin, J.W.2
Belch, J.J.F.3
-
144
-
-
80053654196
-
Changes in HIF-1 protein, pyruvate dehydrogenase phosphorylation, and activity with exercise in acute and chronic hypoxia
-
C. M. R. leMoine, A. J. Morash, and G. B. McClelland, "Changes in HIF-1 protein, pyruvate dehydrogenase phosphorylation, and activity with exercise in acute and chronic hypoxia," American Journal of Physiology: Regulatory Integrative and Comparative Physiology, vol. 301, no. 4, pp. R1098-R1104, 2011
-
(2011)
American Journal of Physiology: Regulatory Integrative and Comparative Physiology
, vol.301
, Issue.4
, pp. R1098-R1104
-
-
Lemoine, C.M.R.1
Morash, A.J.2
McClelland, G.B.3
-
145
-
-
59549107216
-
Effect of intermittent hypoxic training on HIF gene expression in human skeletal muscle and leukocytes
-
R. Mounier, V. Pialoux, B. Roels et al., "Effect of intermittent hypoxic training on HIF gene expression in human skeletal muscle and leukocytes," European Journal of Applied Physiology, vol. 105, no. 4, pp. 515-524, 2009
-
(2009)
European Journal of Applied Physiology
, vol.105
, Issue.4
, pp. 515-524
-
-
Mounier, R.1
Pialoux, V.2
Roels, B.3
-
146
-
-
84908665955
-
HIF-1alpha and HIF-2alpha induce angiogenesis and improve muscle energy recovery
-
H. Niemi, K. Honkonen, P. Korpisalo et al., "HIF-1alpha and HIF-2alpha induce angiogenesis and improve muscle energy recovery," European Journal of Clinical Investigation, vol. 44, no. 10, pp. 989-999, 2014
-
(2014)
European Journal of Clinical Investigation
, vol.44
, Issue.10
, pp. 989-999
-
-
Niemi, H.1
Honkonen, K.2
Korpisalo, P.3
-
147
-
-
84865407427
-
HIF-3 mRNA expression changes in different tissues and their role in adaptation to intermittent hypoxia and physical exercise
-
T. Drevytska, B. Gavenauskas, S. Drozdovska, V. Nosar, V. Dosenko, and I. Mankovska, "HIF-3 mRNA expression changes in different tissues and their role in adaptation to intermittent hypoxia and physical exercise," Pathophysiology, vol. 19, no. 3, pp. 205-214, 2012.
-
(2012)
Pathophysiology
, vol.19
, Issue.3
, pp. 205-214
-
-
Drevytska, T.1
Gavenauskas, B.2
Drozdovska, S.3
Nosar, V.4
Dosenko, V.5
Mankovska, I.6
|