Low-dose radiation exposure induces a HIF-1-mediated adaptive and protective metabolic response

Cell Death and Differentiation

Volumn 21, Issue 5, 2014, Pages 836-844

  Lall, R ^a   Ganapathy, S ^b   Yang, M ^b   Xiao, S ^a,e   Xu, T ^a   Su, H ^a   Shadfan, M ^a   Asara, J M ^c,d   Ha, C S ^a   Ben Sahra, I ^b   Manning, B D ^b   Little, J B ^b   Yuan, Z M ^b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUCOSE TRANSPORTER; GLYCOLYTIC ENZYME; HISTONE H2AX; HYPOXIA INDUCIBLE FACTOR 1; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER 2; MONOCARBOXYLATE TRANSPORTER 3; MONOCARBOXYLATE TRANSPORTER 4; MONOCARBOXYLATE TRANSPORTER 6; MONOCARBOXYLATE TRANSPORTER 8; OXYGEN; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

AEROBIC GLYCOLYSIS; APOPTOSIS; ARTICLE; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; CITRIC ACID CYCLE; CONTROLLED STUDY; DISEASE MARKER; DNA DAMAGE; DOWN REGULATION; FIBROBLAST; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INDUCED RESISTANCE; IRRADIATION; LOW ENERGY RADIATION; LYMPHOCYTE; METABOLIC FLUX ANALYSIS; MITOCHONDRIAL GENE; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONCENTRATION; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIATION DOSE; RADIATION RESPONSE; RADIOADAPTIVE RESPONSE; RADIOSENSITIVITY; UPREGULATION; ADAPTATION; ANIMAL; B LYMPHOCYTE; BAGG ALBINO MOUSE; MITOCHONDRION; TUMOR CELL LINE;

MUS;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; B-LYMPHOCYTES; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, RADIATION; FIBROBLASTS; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, INBRED BALB C; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION;

EID: 84898052710     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2014.24     Document Type: Article

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