Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

Cell Metabolism

Volumn 1, Issue 6, 2005, Pages 401-408

  Guzy, Robert D ^a   Hoyos, Beatrice ^b   Robin, Emmanuel ^a   Chen, Hong ^a   Liu, Liping ^c,d   Mansfield, Kyle D ^d   Simon, M Celeste ^c,d   Hammerling, Ulrich ^b   Schumacker, Paul T ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; OXYGEN; REACTIVE OXYGEN METABOLITE; UBIQUINOL CYTOCHROME C REDUCTASE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HIF1A PROTEIN, HUMAN; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 2, ALPHA SUBUNIT; HYPOXIA-INDUCIBLE FACTOR 2, ALPHA SUBUNIT; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; HYPOXIA; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXYGEN CONCENTRATION; OXYGEN SENSING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN STABILITY; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; ANOXIA; ENZYMOLOGY; METABOLISM; MITOCHONDRION; TUMOR CELL LINE;

ANOXIA; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE, TUMOR; ELECTRON TRANSPORT COMPLEX III; HUMANS; HYDROGEN PEROXIDE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MITOCHONDRIA; OXYGEN; REACTIVE OXYGEN SPECIES; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 24144493814     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2005.05.001     Document Type: Article

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