Molecular, functional, and gene expression analysis of zebrafish hypoxia-inducible factor-3α

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 303, Issue 11, 2012, Pages

  Zhang, Peng ^a   Lu, Ling ^a   Yao, Qing ^a   Li, Yun ^a   Zhou, Jianfeng ^a   Liu, Yunzhang ^a   Duan, Cunming ^b  

^a Ocean University of China   (China)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Danio rerio; Embryos; Gene expression; HIF; Oxygen tension

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 3ALPHA; HYPOXIA INDUCIBLE FACTOR 4ALPHA; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN 1A; MESSENGER RNA; SOMATOMEDIN BINDING PROTEIN; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; OXYGEN;

ANIMAL EXPERIMENT; ARTICLE; CELL NUCLEUS; CELL STRAIN HEK293; EMBRYO; FEMALE; FERTILIZATION; GENE EXPRESSION; GENE STRUCTURE; HELA CELL; HUMAN; HUMAN CELL; HYPOXIA; IN SITU HYBRIDIZATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SYNTHESIS; ZEBRA FISH; AMINO ACID SEQUENCE; ANIMAL; ANOXIA; DNA RESPONSIVE ELEMENT; GENE EXPRESSION REGULATION; GENETICS; LARVA; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PHYLOGENY; PHYSIOLOGY; PRENATAL DEVELOPMENT; ANIMAL TISSUE; CELL CULTURE; CHROMOSOME; GENETIC TRANSFECTION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

AMINO ACID SEQUENCE; ANIMALS; ANOXIA; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEK293 CELLS; HELA CELLS; HUMANS; LARVA; MOLECULAR SEQUENCE DATA; OXYGEN; PHYLOGENY; RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; ZEBRAFISH;

EID: 84870497082     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00340.2012     Document Type: Article

References (44)

1. Bickler PE, Buck LT. Hypoxia tolerance in reptiles, amphibians, and fishes: life with variable oxygen availability. Annu Rev Physiol 69: 145-170, 2007.
2. Erbel PJ, Card PB, Karakuzu O, Bruick RK, Gardner KH. Structural basis for PAS domain heterodimerization in the basic helix-loop-helix-PAS transcription factor hypoxia-inducible factor. Proc Natl Acad Sci USA 100: 15504-15509, 2003.
3. Gordan JD, Simon MC. Hypoxia-inducible factors: central regulators of the tumor phenotype. Curr Opin Genet Dev 17: 71-77, 2007.
4. Gu YZ, Moran SM, Hogenesch JB, Wartman L, Bradfield CA. Molecular characterization and chromosomal localization of a third alphaclass hypoxia inducible factor subunit, HIF3alpha. Gene Expr 7: 205-213, 1998.
5. Guindon S, Gascuel O. A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst Biol 52: 696-704, 2003.
6. Hara S, Hamada J, Kobayashi C, Kondo Y, Imura N. Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha. Biochem Biophys Res Commun 287: 808-813, 2001.
7. Heidbreder M, Frohlich F, Johren O, Dendorfer A, Qadri F, Dominiak P. Hypoxia rapidly activates HIF-3alpha mRNA expression. FASEB J 17: 1541-1543, 2003.
8. Richards J, Farrell A, Brauner C. Hypoxia. In: Fish Physiology, 2009, 528 p.
9. Kajimura S, Aida K, Duan C. Insulin-like growth factor-binding protein-1 (IGFBP-1) mediates hypoxia-induced embryonic growth and developmental retardation. Proc Natl Acad Sci USA 102: 1240-1245, 2005.
10. Kajimura S, Aida K, Duan C. Understanding hypoxia-induced gene expression in early development: in vitro and in vivo analysis of hypoxiainducible factor 1-regulated zebra fish insulin-like growth factor binding protein 1 gene expression. Mol Cell Biol 26: 1142-1155, 2006.
11. Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF. Stages of embryonic development of the zebrafish. Dev Dyn 203: 253-310, 1995.
12. Kumar S, Nei M, Dudley J, Tamura K. MEGA: a biologist-centric software for evolutionary analysis of DNA and protein sequences. Brief Bioinform 9: 299-306, 2008.
13. Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev 16: 1466-1471, 2002.
14. Law SH, Wu RS, Ng PK, Yu RM, Kong RY. Cloning and expression analysis of two distinct HIF-α isoforms-gcHIF-1α and gcHIF-4α-from the hypoxia-tolerant grass carp, Ctenopharyngodon idellus. BMC Mol Biol 7: 15, 2006.
15. Li QF, Wang XR, Yang YW, Lin H. Hypoxia upregulates hypoxia inducible factor (HIF)-3alpha expression in lung epithelial cells: characterization and comparison with HIF-1alpha. Cell Res 16: 548-558, 2006.
16. Li Y, Xiang J, Duan C. Insulin-like growth factor-binding protein-3 plays an important role in regulating pharyngeal skeleton and inner ear formation and differentiation. J Biol Chem 280: 3613-3620, 2005.
17. Makino Y, Cao R, Svensson K, Bertilsson G, Asman M, Tanaka H, Cao Y, Berkenstam A, Poellinger L. Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression. Nature 414: 550-554, 2001.
18. Makino Y, Uenishi R, Okamoto K, Isoe T, Hosono O, Tanaka H, Kanopka A, Poellinger L, Haneda M, Morimoto C. Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): a negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells. J Biol Chem 282: 14073-14082, 2007.
19. Maynard MA, Qi H, Chung J, Lee EH, Kondo Y, Hara S, Conaway RC, Conaway JW, Ohh M. Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex. J Biol Chem 278: 11032-11040, 2003.
20. Min JH, Yang H, Ivan M, Gertler F, Kaelin WG Jr, Pavletich NP. Structure of an HIF-1α-pVHL complex: hydroxyproline recognition in signaling. Science 296: 1886-1889, 2002.
21. Nikinmaa M, Rees BB. Oxygen-dependent gene expression in fishes. Am J Physiol Regul Integr Comp Physiol 288: R1079-R1090, 2005.
22. Pasanen A, Heikkila M, Rautavuoma K, Hirsila M, Kivirikko KI, Myllyharju J. Hypoxia-inducible factor (HIF)-3α is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2. Int J Biochem Cell Biol 42: 1189-1200, 2010.
23. Patel SA, Simon MC. Biology of hypoxia-inducible factor-2α in development and disease. Cell Death Differ 15: 628-634, 2008.
24. Pereira T, Zheng X, Ruas JL, Tanimoto K, Poellinger L. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1α by the von Hippel-Lindau tumor suppressor gene product. J Biol Chem 278: 6816-6823, 2003.
25. 2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2. Ann NY Acad Sci 973: 443-447, 2002.
26. Pugh CW, O'Rourke JF, Nagao M, Gleadle JM, Ratcliffe PJ. Activation of hypoxia-inducible factor-1; definition of regulatory domains within the alpha subunit. J Biol Chem 272: 11205-11214, 1997.
27. Rahman MS, Thomas P. Molecular cloning, characterization and expression of two hypoxia-inducible factor alpha subunits, HIF-1α and HIF-2α, in a hypoxia-tolerant marine teleost, Atlantic croaker (Micropogonias undulatus). Gene 396: 273-282, 2007.
28. Rankin EB, Giaccia AJ. The role of hypoxia-inducible factors in tumorigenesis. Cell Death Differ 15: 678-685, 2008.
29. Rojas DA, Perez-Munizaga DA, Centanin L, Antonelli M, Wappner P, Allende ML, Reyes AE. Cloning of hif-1α and hif-2α and mRNA expression pattern during development in zebrafish. Gene Expr Patterns 7: 339-345, 2007.
30. Schlueter PJ, Peng G, Westerfield M, Duan C. Insulin-like growth factor signaling regulates zebrafish embryonic growth and development by promoting cell survival and cell cycle progression. Cell Death Differ 14: 1095-1105, 2007.
31. Schlueter PJ, Royer T, Farah MH, Laser B, Chan SJ, Steiner DF, Duan C. Gene duplication and functional divergence of the zebrafish insulin-like growth factor 1 receptors. FASEB J 20: 1230-1232, 2006.
32. Semenza GL. HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 88: 1474-1480, 2000.
33. Semenza GL. Life with oxygen. Science 318: 62-64, 2007.
34. Semenza GL. Oxygen homeostasis. Rev Syst Biol Med 2: 336-361, 2010.
35. Simon MC, Keith B. The role of oxygen availability in embryonic development and stem cell function. Nat Rev 9: 285-296, 2008.
36. Soitamo AJ, Rabergh CM, Gassmann M, Sistonen L, Nikinmaa M. Characterization of a hypoxia-inducible factor (HIF-1α) from rainbow trout. Accumulation of protein occurs at normal venous oxygen tension. J Biol Chem 276: 19699-19705, 2001.
37. Terova G, Rimoldia S, Cora'a S, Bernardinia G, Gornatia R, Sarogliaa M. Acute and chronic hypoxia affects HIF-1α mRNA levels in sea bass (Dicentrarchus labrax). Aquaculture 279: 150-159, 2008.
38. Tian H, McKnight SL, Russell DW. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev 11: 72-82, 1997.
39. Weidemann A, Johnson RS. Biology of HIF-1α. Cell Death Differ 15: 621-627, 2008.
40. Wiener CM, Booth G, Semenza GL. In vivo expression of mRNAs encoding hypoxia-inducible factor 1. Biochem Biophys Res Commun 225: 485-488, 1996.
41. Wood AW, Schlueter PJ, Duan C. Targeted knockdown of insulin-like growth factor binding protein-2 disrupts cardiovascular development in zebrafish embryos. Mol Endocrinol 19: 1024-1034, 2005.
42. Xu Q, Li S, Zhao Y, Maures TJ, Yin P, Duan C. Evidence that IGF binding protein-5 functions as a ligand-independent transcriptional regulator in vascular smooth muscle cells. Circ Res 94: E46-E54, 2004.
43. Yamashita T, Ohneda O, Nagano M, Iemitsu M, Makino Y, Tanaka H, Miyauchi T, Goto K, Ohneda K, Fujii-Kuriyama Y, Poellinger L, Yamamoto M. Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS. Mol Cell Biol 28: 1285-1297, 2008.
44. Zou S, Kamei H, Modi Z, Duan C. Zebrafish IGF genes: gene duplication, conservation and divergence, and novel roles in midline and notochord development. PLos One 4: e7026, 2009.