Reciprocal positive regulation of hypoxia-inducible factor 1α and insulin-like growth factor 2

Cancer Research

Volumn 59, Issue 16, 1999, Pages 3915-3918

  Feldser, David ^a   Agani, Faton ^a   Iyer, Narayan V ^a   Pak, Brian ^a   Ferreira, Gloria ^a   Semenza, Gregg L ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOCRINE MOTILITY FACTOR; SOMATOMEDIN B;

ANIMAL CELL; ARTICLE; CELL DENSITY; ENERGY METABOLISM; GENE ACTIVATION; GENETIC TRANSCRIPTION; GLUCOSE TRANSPORT; GLYCOLYSIS; HYPOXIA; NONHUMAN; OXYGEN TRANSPORT; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; VASCULAR ENDOTHELIUM;

ANIMALS; AUTOCRINE COMMUNICATION; CELL LINE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS;

EID: 0033566693     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. 2 tension. Proc. Natl. Acad. Sci. USA, 92: 5510-5514, 1995.
2. 2 homeostasis. Curr. Opin. Genet. Dev., 8: 588-594, 1998.
3. Carmeliet, P., Dor, Y., Herbert, J-M., Fukumura, D., Brusselmans, K., Dewerchin, M., Neeman, M., Bono, F., Abramovich, R., Maxwell, P., Koch, C. J., Ratcliffe, P. J., Moons, L., Jain, R. K., Collen, D., and Keshet, E. Role of HIF-1α in hypoxiamediated apoptosis, cell proliferation, and tumour angiogenesis. Nature (Lond.), 394: 485-490, 1998.
4. 2 homeostasis by hypoxia-inducible factor 1α. Genes Dev., 12: 149-162, 1998.
5. Ryan, H. E., Lo, J., and Johnson, R. S. HIF-1α is required for solid tumor formation and embryonic vascularization. EMBO J., 17: 3005-3015, 1998.
6. Agani, F., and Semenza, G. L. Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activity. Mol. Pharmacol., 54: 749-754, 1998.
7. Zelzer, E., Levy, Y., Kahana, C., Shilo, B-Z., Rubinstein, M., and Cohen, B. Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1α/ ARNT. EMBO J., 17: 5085-5094, 1998.
8. Sell, C., Dumenil, G., Deveaud, C., Miura, M., Coppola, D., DeAngelis, T., Rubin, R., Efstratiadis, A., and Baserga, R. Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol. Cell. Biol., 14: 3604-3612, 1994.
9. Perucho, M., Hanahan, D., and Wigler, M. Genetic and physical linkage of exogenous sequences in transformed cells. Cell, 22: 309-317, 1980.
10. Duan, C., and Clemmons, D. R. Differential expression and biological effects of insulin-like growth factor-binding protein-4 and -5 in vascular smooth muscle cells. J. Biol. Chem., 273: 16836-16842, 1998.
11. Tazuke, S. I., Mazure, N. M., Sugawara, J., Carland, G., Faessen, G. H., Suen, L-F., Irwin, J. C., Powell, D. R., Giaccia, A. J., and Giudice, L. C. Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia. Proc. Natl. Acad. Sci. USA, 95: 10188-10193, 1998.
12. Averbukh, E., Weiss, O., Halpert, M., Yanko, R., Moshe, R., Nephesh, I., Flyvbjerg, A., Yanko, L., and Raz, I. Gene expression of insulin-like growth factor-I, its receptor and binding proteins in retina under hypoxic conditions. Metabolism, 47: 1331-1336, 1998.
13. Kim, K. W., Bae, S. K., Lee, O. H., Bae, M. H., Lee, M. J., and Park, B. C. Insulin-like growth factor II induced by hypoxia may contribute to angiogenesis of human hepatocellular carcinoma. Cancer Res., 58: 348-351, 1998.
14. Tucci, M., Nygard, K., Tanswell, B. V., Farber, H. W., Hill, D. J., and Han, V. K. M. Modulation of insulin-like growth factor (IGF) and IGF binding protein biosynthesis by hypoxia in cultured vascular endothelial cells. J. Endocrinol., 157: 13-24, 1998.
15. Zhong, H., Agani, F., Baccala, A. A., Laughner, E., Rioseco-Camacho, N., Isaacs, W. B., Simons, J. W., and Semenza, G. L. Increased expression of hypoxiainducible factor 1α in rat and human prostate cancer. Cancer Res., 58: 5280-5284, 1998.
16. Brand, K. A., and Hermfisse, U. Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species. FASEB J., 11: 388-395, 1997.
17. Zhang, L., Zhou, W., Velculescu, V., Kern, S. E., Hruban, R. H., Hamilton, S. R., Vogelstein, B., and Kinzler, K. W. Gene expression profiles in normal and cancer cells. Science (Washington DC), 276: 1268-1272, 1997.
18. Manes, S., Llorente, M., Lacalle, R. A., Gomez-Mouton, C., Kremer, L., Mira, E., and Martinez-A. C. The matrix metalloproteinase-9 regulates insulin-like growth factor-triggered autocrine response in DU-145 carcinoma cells. J. Biol. Chem., 274: 6935-6945, 1999.
19. Jiang, B.-H., Agani, F., Passaniti, A., and Semenza, G. L. V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression. Cancer Res., 57: 5328-5335, 1997.
20. Maxwell, P. H., Dachs, G. U., Gleadle, J. M., Nicholls, L. G., Harris, A. L., Stratford, I. J., Hankinson, O., Pugh, C. W., and Ratcliffe, P. J. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc. Natl. Acad. Sci. USA, 94: 8104-8109, 1997.