Regulation of hypoxia-inducible factor 1α is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 14, 1998, Pages 7987-7992

  Huang, L Eric ^a   Gu, Jie ^a   Schau, Maureen ^a   Bunn, H Franklin ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN; PROTEASOME; TRANSCRIPTION FACTOR; UBIQUITIN;

ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; CELL HYPOXIA; CELL LINE; CYSTEINE ENDOPEPTIDASES; DIMERIZATION; DNA; DNA-BINDING PROTEINS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MULTIENZYME COMPLEXES; NUCLEAR PROTEINS; OXYGEN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UBIQUITINS;

EID: 0032493368     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.14.7987     Document Type: Article

References (39)

1. Bunn, H. F. & Poyton, R. O. (1996) Physiol. Rev. 76, 839-885.
2. Guillemin, K. & Krasnow, M. A. (1997) Cell 89, 9-12.
3. Semenza, G. L. & Wang, G. L. (1992) Mol. Cell. Biol. 12, 5447-5454.
4. Wang, G. L. & Semenza, G. L. (1993) J. Biol. Chem. 268, 21513-21518.
5. Wang, G. L., Jiang, B.-H., Rue, E. A. & Semenza, G. L. (1995) Proc. Natl. Acad. Sci. USA 92, 5510-5514.
6. Hoffman, E. C., Reyes, H., Chu, F.-F., Sander, F., Conley, L. H., Brooks, B. A. & Hankinson, O. (1991) Science 252, 954-958.
7. Reisz-Porszasz, S., Probst, M., Fukunaga, B. & Hankinson, O. (1994) Mol. Cell. Biol. 14, 6075-6086.
8. Jiang, B.-H., Rue, E., Wang, G. L., Roe, R. & Semenza, G. L. (1996) J. Biol. Chem. 271, 17771-17778.
9. Huang, Z. J., Edery, I. & Rosbach, M. (1993) Nature (London) 364, 259-262.
10. Lindebro, M. C., Poellinger, L. & Whitelaw, M. L. (1995) EMBO J. 14, 3528-3539.
11. Zelzer, E., Wappner, P. & Shilo, B.-Z. (1997) Genes Dev. 11, 2079-2089.
12. Jain, S., Dolwick, K. M., Schmidt, J. V. & Bradfield, C. A. (1994) J. Biol. Chem. 269, 31518-31524.
13. Li, H., Dong, L. & Whitlock, J. P. (1994) J. Biol. Chem. 269, 28098-28105.
14. Wood, S. M., Gleadle, J. M., Pugh, C. W., Hankinson, O. & Ratcliffe, P. J. (1996) J. Biol. Chem. 269, 15117-15123.
15. Li, H., Ko, H. P. & Whitlock, J. P. (1996) J. Biol. Chem. 271, 21262-21267.
16. Jiang, B.-H., Zheng, J. Z., Leung, S. W., Roe, R. & Semenza, G. L. (1997) J. Biol. Chem. 272, 19253-19260.
17. Pugh, C. W., O'Rourke, J. F., Nagao, M., Gleadle, J. M. & Ratcliffe, P. J. (1997) J. Biol. Chem. 272, 11205-11214.
18. Wang, G. L., Jiang, B.-H. & Semenza, G. L. (1995) Biochem. Biophys. Res. Commun. 216, 669-675.
19. Gradin, K., McGuire, J., Wenger, R. H., Kvietikova, I., Whitelaw, M., Toftgard, R., Tora, L., Gassman, M. & Poellinger, L. (1996) Mol. Cell. Biol. 16, 5221-5231.
20. Kallio, P. J., Pongratz, I., Gradin, K., McGuire, J. & Poellinger, L. (1997) Proc. Natl. Acad. Sci. USA 94, 5667-5672.
21. Huang, L. E., Arany, Z., Livingston, D. M. & Bunn, H. F. (1996) J. Biol. Chem. 271, 32253-32259.
22. Bhattacharya, S., Eckner, R., Grossman, S., Oldread, E., Arany, Z., D'Andrea, A. & Livingston, D. M. (1996) Nature (London) 383, 344-347.
23. Gu, J., Parthasarathi, S., Varela-Echavarria, A., Ron, Y. & Dougherty, J. P. (1995) Virology 206, 885-893.
24. Rock, K., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D. & Goldberg, A. (1994) Cell 78, 761-771.
25. Wang, G. L. & Semenza, G. L. (1993) Blood 82, 3610-3615.
26. Rogers, S., Wells, R. & Rechsteiner, M. (1986) Science 234, 364-368.
27. Rechsteiner, M. & Rogers, S. W. (1996) Trends Biochem. Sci. 21.
28. Ciechanover, A. (1994) Cell 79, 13-21.
29. Coux, O., Tanaka, K. & Goldberg, A. L. (1996) Annu. Rev. Biochem. 65, 801-847.
30. Hilt, W. & Wolf, D. H. (1996) Trends Biochem. Sci. 21, 96-102.
31. Salceda, S. & Caro, J. (1997) J. Biol. Chem. 272, 22642-22547.
32. Tian, H., McKnight, S. L. & Russell, D. W. (1997) Genes Dev. 11, 72-82.
33. Ema, M., Taya, S., Yokotani, N., Sogawa, K., Matsuda, Y. & Fujii-Kuriyama, Y. (1997) Proc. Natl. Acad. Sci. USA 94, 4273-4278.
34. Hogenesch, J. B., Chan, W. K., Jackiw, V. H., Brown, R. C., Gu, Y.-Z., Pray-Grant, M., Perdew, G. H. & Bradfield, C. A. (1997) J. Biol. Chem. 272, 8581-8593.
35. Hankinson, O. (1995) Annu. Rev. Pharmacol. Toxicol. 35, 307-340.
36. Hateboer, G., Kerkhoven, R. M., Shvarts, A., Bernards, R. & Beijersbergen, R. L. (1996) Genes & Dev. 10, 2960-2970.
37. Hoffman, F., Martelli, F., Livingston, D. M. & Wang, Z. (1996) Genes & Dev. 10, 2949-2959.
38. Tsurumi, C., Ishida, N., Tamura, T., Kakizuka, A., NIshida, E., Okumura, E., Kishimoto, T., Inagaki, M., Okazaki, K., Sagata, N., Ichihara, A. & Tanaka, K. (1995) Mol. Cell. Biol. 15, 5682-5687.
39. Lee, D. H. & Goldberg, A. L. (1996) J. Biol. Chem. 271, 27280-27284.