-
3
-
-
15444342958
-
2 homeostasis by hypoxia-inducible factor 1 α
-
2 homeostasis by hypoxia-inducible factor 1 α. Genes Dev 12:149-162.
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
-
4
-
-
33751329032
-
Heterozygous HIF-1α deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia
-
DOI 10.1113/jphysiol.2006.114033
-
Peng Y-J, et al. (2006) Heterozygous HIF-1α deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia. J Physiol 577:705-716. (Pubitemid 44804021)
-
(2006)
Journal of Physiology
, vol.577
, Issue.2
, pp. 705-716
-
-
Peng, Y.-J.1
Yuan, G.2
Ramakrishnan, D.3
Sharma, S.D.4
Bosch-Marce, M.5
Kumar, G.K.6
Semenza, G.L.7
Prabhakar, N.R.8
-
5
-
-
0037154262
-
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
-
DOI 10.1073/pnas.022634199
-
Kline DD, Peng YJ, Manalo DJ, Semenza GL, Prabhakar NR (2002) Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 α. Proc Natl Acad Sci USA 99:821-826. (Pubitemid 34106594)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.2
, pp. 821-826
-
-
Kline, D.D.1
Peng, Y.-J.2
Manalo, D.J.3
Semenza, G.L.4
Prabhakar, N.R.5
-
6
-
-
0033948805
-
Oxygen sensing by the carotid body chemoreceptors
-
Prabhakar NR (2000) Oxygen sensing by the carotid body chemoreceptors. J Appl Physiol 88:2287-2295.
-
(2000)
J Appl Physiol
, vol.88
, pp. 2287-2295
-
-
Prabhakar, N.R.1
-
7
-
-
35248848916
-
Sensing hypoxia in the carotid body: From stimulus to response
-
Kumar P (2007) Sensing hypoxia in the carotid body: From stimulus to response. Essays Biochem 43:43-60.
-
(2007)
Essays Biochem
, vol.43
, pp. 43-60
-
-
Kumar, P.1
-
8
-
-
0033104847
-
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
-
Yu AY, et al. (1999) Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α. J Clin Invest 103:691-696. (Pubitemid 29122422)
-
(1999)
Journal of Clinical Investigation
, vol.103
, Issue.5
, pp. 691-696
-
-
Yu, A.Y.1
Shimoda, L.A.2
Iyer, N.V.3
Huso, D.L.4
Sun, X.5
McWilliams, R.6
Beaty, T.7
Sham, J.S.K.8
Wiener, C.M.9
Sylvester, J.T.10
Semenza, G.L.11
-
9
-
-
0031020884
-
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
-
Tian H, McKnight SL, Russell DW (1997) Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev 11:72-82. (Pubitemid 27043825)
-
(1997)
Genes and Development
, vol.11
, Issue.1
, pp. 72-82
-
-
Tian, H.1
McKnight, S.L.2
Russell, D.W.3
-
10
-
-
0031000736
-
A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development
-
Ema M, et al. (1997) A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci USA 94:4273-4278.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4273-4278
-
-
Ema, M.1
-
11
-
-
33750630119
-
Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype
-
DOI 10.1016/j.ccr.2006.08.026, PII S153561080600290X
-
Holmquist-Mengelbier L, et al. (2006) Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype. Cancer Cell 10:413-423. (Pubitemid 44693470)
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 413-423
-
-
Holmquist-Mengelbier, L.1
Fredlund, E.2
Lofstedt, T.3
Noguera, R.4
Navarro, S.5
Nilsson, H.6
Pietras, A.7
Vallon-Christersson, J.8
Borg, A.9
Gradin, K.10
Poellinger, L.11
Pahlman, S.12
-
13
-
-
85047691081
-
Heterozygous deficiency of hypoxia-inducible factor-2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia
-
DOI 10.1172/JCI200315496
-
Brusselmans K, et al. (2003) Heterozygous deficiency of hypoxia-inducible factor-2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia. J Clin Invest 111:1519-1527. (Pubitemid 38063284)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.10
, pp. 1519-1527
-
-
Brusselmans, K.1
Compernolle, V.2
Tjwa, M.3
Wiesener, M.S.4
Maxwell, P.H.5
Collen, D.6
Carmeliet, P.7
-
14
-
-
47249111254
-
HIF-2α-haploinsufficient mice have blunted retinal neovascularization due to impaired expression of a proangiogenic gene battery
-
Dioum EM, Clarke SL, Ding K, Repa JJ, Garcia JA (2008) HIF-2α-haploinsufficient mice have blunted retinal neovascularization due to impaired expression of a proangiogenic gene battery. Invest Ophthalmol Vis Sci 49:2714-2720.
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 2714-2720
-
-
Dioum, E.M.1
Clarke, S.L.2
Ding, K.3
Repa, J.J.4
Garcia, J.A.5
-
15
-
-
17044378251
-
HIF-2α regulates murine hematopoietic development in an erythropoietin-dependent manner
-
Scortegagna M, et al. (2005) HIF-2α regulates murine hematopoietic development in an erythropoietin-dependent manner. Blood 105:3133-3140.
-
(2005)
Blood
, vol.105
, pp. 3133-3140
-
-
Scortegagna, M.1
-
16
-
-
0032213236
-
The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
-
Tian H, Hammer RE, Matsumoto AM, Russell DW, McKnight SL (1998) The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes Dev 12:3320-3324. (Pubitemid 28520979)
-
(1998)
Genes and Development
, vol.12
, Issue.21
, pp. 3320-3324
-
-
Tian, H.1
Hammer, R.E.2
Matsumoto, A.M.3
Russell, D.W.4
McKnight, S.L.5
-
17
-
-
0034769177
-
Do existing measures of Poincaré plot geometry reflect nonlinear features of heart rate variability?
-
DOI 10.1109/10.959330, PII S0018929401061626
-
Brennan M, Palaniswami M, Kamen P (2001) Do existing measures of Poincaré plot geometry reflect nonlinear features of heart rate variability? IEEE Trans Biomed Eng 48:1342-1347. (Pubitemid 32988575)
-
(2001)
IEEE Transactions on Biomedical Engineering
, vol.48
, Issue.11
, pp. 1342-1347
-
-
Brennan, M.1
Palaniswami, M.2
Kamen, P.3
-
18
-
-
0036121191
-
Aconitase: Sensitive target and measure of superoxide
-
Gardner PR (2002) Aconitase: Sensitive target and measure of superoxide. Methods Enzymol 349:9-23.
-
(2002)
Methods Enzymol
, vol.349
, pp. 9-23
-
-
Gardner, P.R.1
-
20
-
-
79952606502
-
NADPH Oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: Relevance to blood pressure changes in rats
-
Khan SA, et al. (2011) NADPH Oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: Relevance to blood pressure changes in rats. Antioxid Redox Signal 11:2607-2619.
-
(2011)
Antioxid Redox Signal
, vol.11
, pp. 2607-2619
-
-
Khan, S.A.1
-
21
-
-
33644817266
-
Mathematical models of periodic breathing and their usefulness in understanding cardiovascular and respiratory disorders
-
DOI 10.1113/expphysiol.2005.032268
-
Cherniack NS, Longobardo GS (2006) Mathematical models of periodic breathing and their usefulness in understanding cardiovascular and respiratory disorders. Exp Physiol 91:295-305. (Pubitemid 43356957)
-
(2006)
Experimental Physiology
, vol.91
, Issue.2
, pp. 295-305
-
-
Cherniack, N.S.1
Longobardo, G.S.2
-
22
-
-
0032818626
-
Ventilatory instability during sleep onset in individuals with high peripheral chemosensitivity
-
Dunai J, Kleiman J, Trinder J (1999) Ventilatory instability during sleep onset in individuals with high peripheral chemosensitivity. J Appl Physiol 87:661-672. (Pubitemid 29375003)
-
(1999)
Journal of Applied Physiology
, vol.87
, Issue.2
, pp. 661-672
-
-
Dunai, J.1
Kleiman, J.2
Trinder, J.3
-
24
-
-
34249704041
-
Hypoxia-inducible factor 2α regulates expression of the mitochondrial aconitase chaperone protein frataxin
-
DOI 10.1074/jbc.M611133200
-
Oktay Y, et al. (2007) Hypoxia-inducible factor 2α regulates expression of the mitochondrial aconitase chaperone protein frataxin. J Biol Chem 282:11750-11756. (Pubitemid 47100692)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.16
, pp. 11750-11756
-
-
Oktay, Y.1
Dioum, E.2
Matsuzaki, S.3
Ding, K.4
Yan, L.-J.5
Haller, R.G.6
Szweda, L.I.7
Garcia, J.A.8
-
25
-
-
45949111351
-
Regulation of blood pressure, natriuresis and renal thiazide/amiloride sensitivity in PPARalpha null mice
-
DOI 10.1080/08037050701789278, PII 788419453
-
Obih P, Oyekan AO (2008) Regulation of blood pressure, natriuresis and renal thiazide/amiloride sensitivity in PPARalpha null mice. Blood Press 17:55-63. (Pubitemid 351890493)
-
(2008)
Blood Pressure
, vol.17
, Issue.1
, pp. 55-63
-
-
Obih, P.1
Oyekan, A.2
-
26
-
-
0344393077
-
Cardiac hypertrophy in Aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure
-
DOI 10.1016/j.taap.2003.08.008
-
Lund AK, Goens MB, Kanagy NL, Walker MK (2003) Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure. Toxicol Appl Pharmacol 193:177-187. (Pubitemid 37476433)
-
(2003)
Toxicology and Applied Pharmacology
, vol.193
, Issue.2
, pp. 177-187
-
-
Lund, A.K.1
Goens, M.B.2
Kanagy, N.L.3
Walker, M.K.4
-
27
-
-
34547889942
-
ROS signaling in systemic and cellular responses to chronic intermittent hypoxia
-
DOI 10.1089/ars.2007.1732
-
Prabhakar NR, Kumar GK, Nanduri J, Semenza GL (2007) ROS signaling in systemic and cellular responses to chronic intermittent hypoxia. Antioxid Redox Signal 9:1397-1403. (Pubitemid 47255019)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.9
, pp. 1397-1403
-
-
Prabhakar, N.R.1
Kumar, G.K.2
Nanduri, J.3
Semenza, G.L.4
-
28
-
-
69849096995
-
Insight from animal models into the cognitive consequences of adult sleep-disordered breathing
-
Veasey S (2009) Insight from animal models into the cognitive consequences of adult sleep-disordered breathing. ILAR J 50:307-311.
-
(2009)
ILAR J
, vol.50
, pp. 307-311
-
-
Veasey, S.1
-
29
-
-
59049086571
-
Intermittent hypoxia degrades HIF-2α via calpains resulting in oxidative stress: Implications for recurrent apnea-induced morbidities
-
Nanduri J, et al. (2009) Intermittent hypoxia degrades HIF-2α via calpains resulting in oxidative stress: Implications for recurrent apnea-induced morbidities. Proc Natl Acad Sci USA 106:1199-1204.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1199-1204
-
-
Nanduri, J.1
-
30
-
-
14244256421
-
2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia
-
2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia. J Biol Chem 280:4321-4328.
-
(2005)
J Biol Chem
, vol.280
, pp. 4321-4328
-
-
Yuan, G.1
Nanduri, J.2
Bhasker, C.R.3
Semenza, G.L.4
Prabhakar, N.R.5
-
31
-
-
54049088213
-
2+ signaling, prolyl hydroxylases, and mTOR
-
2+ signaling, prolyl hydroxylases, and mTOR. J Cell Physiol 217:674-685.
-
(2008)
J Cell Physiol
, vol.217
, pp. 674-685
-
-
Yuan, G.1
Nanduri, J.2
Khan, S.3
Semenza, G.L.4
Prabhakar, N.R.5
-
32
-
-
3242740249
-
Role of oxidative stress in intermittent hypoxia-induced immediate early gene activation in rat PC12 cells
-
DOI 10.1113/jphysiol.2003.058503
-
Yuan G, et al. (2004) Role of oxidative stress in intermittent hypoxia-induced immediate early gene activation in rat PC12 cells. J Physiol 557:773-783. (Pubitemid 38961615)
-
(2004)
Journal of Physiology
, vol.557
, Issue.3
, pp. 773-783
-
-
Yuan, G.1
Adhikary, G.2
McCormick, A.A.3
Holcroft, J.J.4
Kumar, G.K.5
Prabhakar, N.R.6
-
33
-
-
0034769177
-
Do existing measures of Poincaré plot geometry reflect nonlinear features of heart rate variability?
-
DOI 10.1109/10.959330, PII S0018929401061626
-
Brennan M, Palaniswami M, Kamen P (2001) Do existing measures of Poincaré plot geometry reflect nonlinear features of heart rate variability? IEEE Trans Biomed Eng 48:1342-1347. (Pubitemid 32988575)
-
(2001)
IEEE Transactions on Biomedical Engineering
, vol.48
, Issue.11
, pp. 1342-1347
-
-
Brennan, M.1
Palaniswami, M.2
Kamen, P.3
|