Effects of hypoxia on energy state and pH in resting pulmonary and femoral arterial smooth muscles

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 275, Issue 6 19-6, 1998, Pages

  Leach, R M ^a   Sheehan, D W ^a   Chacko, V P ^b   Sylvester, J T ^a,c  

^a Division of Pulmonary and Critical Care Medicine   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

^c JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Adenosine 5' triphosphate; Creatine; Intracellular water volume; Phosphocreatine; Phosphorus 31 nuclear magnetic resonance; Phosphorylation potential; Vascular smooth muscle

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE; CREATINE PHOSPHATE;

ANIMAL TISSUE; ARTERY MUSCLE; ARTICLE; CELL ENERGY; CONTROLLED STUDY; ENERGY METABOLISM; FEMORAL ARTERY; HYPOXIA; NONHUMAN; PH; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PULMONARY ARTERY; REOXYGENATION; SIGNAL TRANSDUCTION; SWINE;

EID: 0032414861     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1998.275.6.l1051     Document Type: Article

References (17)

1. Aickin, C. C. Regulation of intracellular pH in smooth muscle cells of the guinea-pig femoral artery. J. Physiol. (Lond.) 479: 331-340, 1994.
2. Austin, C., and S. Wray. A quantitative study of the relation between intracellular pH and force in rat mesenteric vascular smooth muscle. Pflügers Arch. 427: 270-276, 1994.
3. Austin, C., and S. Wray. An investigation of intrinsic buffering power in rat vascular smooth muscle cells. Pflügers Arch. 429: 325-331, 1995.
4. Brown, G. C. Control of respiration and ATP synthesis in mammalian mitochondria and cells. Biochem. J. 284:1-13, 1992.
5. Buescher, P. C., D. B. Pearse, R. P. Pillai, M. C. Litt, M. C. Mitchell, and J. T. Sylvester. Energy state and vasomotor tone in hypoxic pig lungs. J. Appl. Physiol. 70: 1874-1881, 1991.
6. Butler, T. M., and R. E. Davies. High-energy phosphates in smooth muscle. In: Handbook of Physiology. The Cardiovascular System. Vascular Smooth Muscle. Bethesda, MD: Am. Physiol. Soc., 1980, sect. 2, vol. II, chapt. 10, p. 237-252.
7. (+)-ATPase in porcine vascular smooth muscle. J. Physiol. (Lond.) 447: 67-82, 1992.
8. Chandel, N. S., G. R. S. Budinger, and P. T. Schumacker. Molecular oxygen modulates cytochrome c oxidase function. J. Biol. Chem. 271: 18672-18677, 1996.
9. + -induced swine carotid artery contraction. Hypertension 25: 482-489, 1995.
10. Clark, J. F. The creatine kinase system in smooth muscle. Mol. Cell. Biochem. 133-134: 221-232, 1994.
11. Coburn, R. F., S. Moreland, R. S. Moreland, and C. B. Baron. Rate-limiting energy-dependent steps controlling oxidative metabolism-contraction coupling in rabbit aorta. J. Physiol. (Lond.) 448: 473-492, 1992.
12. Ennor, A. H., and L. A. Stocken. The estimation of creatine. Biochemistry 42: 557-563, 1997.
13. Erecinska, M., and D. F. Wilson. Regulation of cellular energy metabolism. J. Membr. Biol. 70: 1-4, 1982.
14. Farrukh, I. S., J. R. Hoidal, and W. H. Barry. Effect of intracellular pH on ferret pulmonary arterial smooth muscle cell calcium homeostasis and pressure. J. Appl. Physiol. 80: 496-505, 1996.
15. Giesen, J., and H. Kammermeier. Relationship of phosphorylation potention and oxygen consumption in isolated perfused rat hearts. J. Mol. Cell. Cardiol. 12: 891-907, 1980.
16. Golding, E. M., W. E. Teague, and G. P. Dobson. Adjustment of K' to varying pH and pMg for the creatine kinase, adenylate kinase and ATP hydrolysis equilibria permitting quantitative bioenergetic assessment. J. Exp. Biol. 198: 1775-1782, 1995.
17. Gordon, J. B., F. R. Martinez, P. A. Keller, M. L. Tod, and J. A. Madden. Differing effects of acute and prolonged alkalosis on hypoxic pulmonary vasoconstriction. Am. Rev. Respir. Dis. 148: 1651-1656, 1993.