Energy state, pH, and vasomotor tone during hypoxia in precontracted pulmonary and femoral arteries

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 278, Issue 2 22-2, 2000, Pages

  Leach, R M ^a   Sheehan, D W ^a   Chacko, V P ^a   Sylvester, J T ^a,b  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Adenosine 5' triphosphate; Cyanide; Endothelium; Glucose; Hypoxic pulmonary vasoconstriction; Phosphate; Phosphocreatine; Phosphorus 31 nuclear magnetic resonance; Swine; Vascular smooth muscle

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; GLUCOSE; PHENYLEPHRINE; SODIUM CYANIDE;

ANIMAL TISSUE; ARTICLE; CELL PH; CONTROLLED STUDY; ENERGY METABOLISM; FEMORAL ARTERY; GLYCOLYSIS; HYPOXIA; LUNG VASOCONSTRICTION; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PULMONARY ARTERY; SMOOTH MUSCLE RELAXATION; SWINE; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASODILATATION; VASOMOTOR REFLEX;

EID: 0034058481     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.278.2.l294     Document Type: Article

References (56)

1. Aalkjaer, C., and H. L. Peng. pH and smooth muscle. Acta Physiol. Scand. 161: 557-566, 1997.
2. Aickin, C. C. Regulation of intracellular pH in smooth muscle cells of the guinea-pig femoral artery. J. Physiol. (Lond.) 479: 331-340, 1994.
3. Arnqvist, H. J., and L. Lundholm, Influence of oxygen tension on the metabolism of vascular smooth muscle: demonstration of a Pasteur effect. Atherosclerosis 25: 245-253, 1976.
4. Austin, C., and S. Wray. A quantitative study of the relation between intracellular pH and force in rat mesenteric vascular smooth muscle. Pflügers Arch. 427: 270-276, 1994.
5. Barron, J. T., S. J. Kopp, J. P. Tow, and J. V. Messer. Effects of altering carbohydrate metabolism on energy status and contractile function of vascular smooth muscle. Biochim. Biophys. Acta 976: 42-52, 1989.
6. Bennie, R. E., C. S. Packer, D. R. Powell, N. Jin, and R. A. Rhoades. Biphasic contractile response of pulmonary artery to hypoxia. Am. J. Physiol. Lung Cell. Mol. Physiol 261: L156-L163, 1991.
7. Berger, M. G., C. Vandier, P. Bonnet, W. F. Jackson, and N. J. Rusch. Intracellular acidosis differentially regulates Kv channels in coronary and pulmonary vascular muscle. Am. J. Physiol. Heart Circ. Physiol. 275: H1351-H1359, 1998.
8. 2 sensor. J. Biol. Chem. 273: 3320-3326, 1998.
9. +-ATPase in porcine vascular smooth muscle. J. Physiol. (Lond.) 447: 67-82, 1992.
10. Cartee, G. D., A. G. Douen, T. Ramlal, A. Klip, and J. O. Holloszy. Stimulation of glucose transport in skeletal muscle by hypoxia. J. Appl. Physiol. 70: 1593-600, 1991.
11. Chandel, N. S., G. R. Budinger, S. H. Choe, and P. T. Schumacker. Cellular respiration during hypoxia. Role of cytochrome oxidase as the oxygen sensor in hepatocytes. J. Biol. Chem. 272: 18808-18816, 1997.
12. Chandel, N. S., G. R. S. Budinger, and P. T. Schumacker. Molecular oxygen modulates cytochrome c oxidase function. J. Biol. Chem. 271: 18672-18677, 1996.
13. Coburn, R. F., R. Eppinger, and D. P. Scott. Oxygen-dependent tension in vascular smooth muscle. Does the endothelium play a role? Circ. Res. 58: 341-347, 1986.
14. Coburn, R. F., S. Moreland, R. S. Moreland, and C. B. Baron. Rate-limiting energy-dependent steps controlling oxidative metabolism-contraction coupling in rabbit aorta. J. Physiol. (Lond.) 448: 473-492, 1992.
15. Daut, J., H. G. Klieber, S. Cyrys, and T. Noack. KATP channels and basal coronary vascular tone. Cardiovasc. Res. 28: 811-817, 1994.
16. Duranteau, J., N. S. Chandel, A. Kulisz, Z. Shao, and P. T. Schumacker. Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. J. Biol. Chem. 273: 11619-11624, 1998.
17. Erecinska, M., and D. F. Wilson. Regulation of cellular energy metabolism. J. Membr. Biol. 70: 1-14, 1982.
18. Farrukh, I. S., J. R. Hoidal, and W. H. Barry. Effect of intracellular pH on ferret pulmonary arterial smooth muscle cell calcium homeostasis and pressure. J. Appl. Physiol. 80: 496-505, 1996.
19. Giesen, J., and H. Kammermeier. Relationship of phosphorylation potential and oxygen consumption in isolated perfused rat hearts. J. Mol. Cell. Cardiol. 12: 891-907, 1980.
20. 13C-NMR. J. Mol. Cell. Cardiol. 26: 1197-1210, 1994.
21. Hardin, C. D., and T. M. Roberts. Differential regulation of glucose and glycogen metabolism in vascular smooth muscle by exogenous substrates. J. Mol. Cell. Cardiol. 29: 1207-1216, 1997.
22. Hellstrand, P., B. Johansson, and K. Norberg. Mechanical, electrical, and biochemical effects of hypoxia and substrate removal on spontaneously active vascular smooth muscle. Acta Physiol. Scand. 100: 69-83, 1977.
23. Iino, S., H. Hayashi, H. Saito, H. Tokuno, and T. Tomita. Effects of intracellular pH on calcium currents and intracellular calcium ions in the smooth muscle of rabbit portal vein. Exp. Physiol. 79: 669-680, 1994.
24. Ishida, Y., I. Riesinger, T. Wallimann, and R. J. Paul. Compartmentation of ATP synthesis and utilization in smooth muscle: roles of aerobic glycolysis and creatine kinase. Mol. Cell. Biochem. 133/134: 39-50, 1994.
25. Katayama, Y., R. F. Coburn, W. S. Fillers, and C. B. Baron. Oxygen sensors in vascular smooth muscle. J. Appl. Physiol. 77: 2086-2092, 1994.
26. 2+ channels. J. Gen. Physiol. 103: 647-663, 1994.
27. Kovitz, K. L., T. D. Aleskowitch, J. T. Sylvester, and N. A. Flavahan. Endothelium-derived contracting and relaxing factors contribute to hypoxic responses of pulmonary arteries. Am. J. Physiol. Heart Circ. Physiol. 265: H1139-H1148, 1993.
28. Krampetz, I. K., and R. A. Rhoades. Intracellular pH: effect on pulmonary arterial smooth muscle. Am. J. Physiol. Lung Cell. Mol. Physiol. 260: L516-L521, 1991.
29. Leach, R. M., H. S. Hill, and J. P. T. Ward. The role of glycolysis in hypoxic pulmonary artery vasoconstriction (HPV) (Abstract). Thorax 53: A13, 1998.
30. Leach, R. M., T. P. Robertson, C. H. Twort, and J. P. Ward. Hypoxic vasoconstriction in rat pulmonary and mesenteric arteries. Am. J. Physiol. Lung Cell. Mol. Physiol. 266: L223-L231, 1994.
31. Leach, R. M., D. W. Sheehan, V. P. Chacko, and J. T. Sylvester. Effects of hypoxia on energy state and pH in resting pulmonary and femoral arterial smooth muscles. Am. J. Physiol. Lung Cell. Mol. Physiol. 275: L1051-L1060, 1998.
32. 2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle. Am. J. Physiol. Heart Circ. Physiol. 272: H987-H994, 1997.
33. + channels in the rabbit. J. Clin. Invest. 90: 733-740, 1992.
34. Lovgren, B., and P. Hellstrand. Graded effects of oxygen and respiratory inhibitors on cell metabolism and spontaneous contractions in smooth muscle of the rat portal vein. Acta Physiol. Scand. 123: 485-495, 1985.
35. Lynch, R. M., and R. J. Paul. Compartmentation of carbohydrate metabolism in vascular smooth muscle: evidence for at least two functionally independent pools of glucose 6-phosphate. Biochim. Biophys. Acta 887: 315-318, 1986.
36. Lynch, R. M., and R. J. Paul. Compartmentation of glycolytic and glycogenolytic metabolism in vascular smooth muscle. Science 222: 1344-1346, 1983.
37. + transport. Am. J. Physiol. Cell Physiol. 247: C433-C440, 1984.
38. Matsumoto, H., C. B. Baron, and R. F. Coburn. Inositol trisphosphate and energy-force coupling in rabbit aorta. J. Pharmacol. Exp. Ther. 270: 708-712, 1994.
39. i in porcine coronary artery smooth muscle. Circ. Res. 75: 990-998, 1994.
40. Nakanishi, T., H. Gu, and K. Momma. Developmental changes in the effect of acidosis on contraction, intracellular pH, and calcium in the rabbit mesenteric small artery. Pediatr. Res. 42: 750-757, 1997.
41. Odessey, R., and K. V. Chace. Utilization of endogenous lipid, glycogen, and protein by rabbit aorta. Am. J. Physiol. Heart Circ. Physiol. 243: H128-H132, 1982.
42. Paul, R. J. Chemical energetics of vascular smooth muscle. In: Handbook of Physiology. The Cardiovascular System. Vascular Smooth Muscle. Bethesda, MD: Am. Physiol. Soc., 1980, sect. 2, vol. II, chapt. 9, p. 201-235.
43. Paul, R. J. Smooth muscle energetics. Annu. Rev. Physiol. 51: 331-349, 1989.
44. Paul, R. J., J. M. Krisanda, and R. M. Lynch. Vascular smooth muscle energetics. J. Cardiovasc. Pharmacol. 6: S320-S327, 1984.
45. i in rat cerebral arteries: is there a role for membrane potential? Am. J. Physiol. Heart Circ. Physiol. 274: H655-H662, 1998.
46. Quayle, J. M., M. T. Nelson, and N. B. Standen. ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. Physiol. Rev. 77: 1165-1232, 1997.
47. + exchange to pH regulation in pulmonary artery smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 5: 586-591, 1991.
48. Rubanyi, G. M. Vascular effects of oxygen-derived free radicals. Free Radic. Biol. Med. 4: 107-120, 1988.
49. Sanders, S. P., J. L. Zweier, P. Kuppusamy, S. J. Harrison, D. J. Bassett, E. W. Gabrielson, and J. T. Sylvester. Hyperoxic sheep pulmonary microvascular endothelial cells generate free radicals via mitochondrial electron transport. J. Clin. Invest. 91: 46-52, 1993.
50. Scott, D. P., and R. F. Coburn. Phosphocreatine and oxidative metabolism-contraction coupling in rabbit aorta. Am. J. Physiol. Heart Circ. Physiol. 257: H597-H602, 1989.
51. Scott, D. P., S. Davidheiser, and R. F. Coburn. Effects of elevation of phosphocreatine on force and metabolism in rabbit aorta. Am. J. Physiol. Heart Circ. Physiol. 253: H461-H465, 1987.
52. Smith, G. L., C. Austin, C. Crichton, and S. Wray. A review of the actions and control of intracellular pH in vascular smooth muscle. Cardiovasc. Res. 38: 316-331, 1998.
53. Spurway, N. C., and S. Wray. A phosphorus nuclear magnetic resonance study of metabolites and intracellular pH in rabbit vascular smooth muscle. J. Physiol. (Lond.) 393: 57-71, 1987.
54. Sward, K., M. Josefsson, M. L. Lydrup, and P. Hellstrand. Effects of metabolic inhibition on cytoplasmic calcium and contraction in smooth muscle of rat portal vein. Acta Physiol. Scand. 148: 265-272, 1993.
55. 2+ channel currents by intracellular ATP in smooth muscle cells of rat mesenteric artery. Am. J. Physiol. Heart Circ. Physiol. 272: H814-H819, 1997.
56. Zhao, Y., C. S. Packer, and R. A. Rhoades. The vein utilizes different sources of energy than the artery during pulmonary hypoxic vasoconstriction. Exp. Lung Res. 22: 51-63, 1996.