-
1
-
-
3542995707
-
Long-term renal allograft survival: have we made significant progress or is it time to rethink our analytic and therapeutic strategies?
-
Meier-Kriesche HU, Schold JD, Kaplan B. Long-term renal allograft survival: have we made significant progress or is it time to rethink our analytic and therapeutic strategies? Am J Transplant (2004) 4(8):1289-95. doi:10.1111/j.1600-6143.2004.00515.x.
-
(2004)
Am J Transplant
, vol.4
, Issue.8
, pp. 1289-1295
-
-
Meier-Kriesche, H.U.1
Schold, J.D.2
Kaplan, B.3
-
2
-
-
0014792798
-
Cell interactions in the induction of tolerance: the role of thymic lymphocytes
-
Gershon RK, Kondo K. Cell interactions in the induction of tolerance: the role of thymic lymphocytes. Immunology (1970) 18(5):723-37.
-
(1970)
Immunology
, vol.18
, Issue.5
, pp. 723-737
-
-
Gershon, R.K.1
Kondo, K.2
-
3
-
-
77955228203
-
Adoptive regulatory T cell therapy: challenges in clinical transplantation
-
Safinia N, Sagoo P, Lechler R, Lombardi G. Adoptive regulatory T cell therapy: challenges in clinical transplantation. Curr Opin Organ Transplant (2010) 15(4):427-34. doi:10.1097/MOT.0b013e32833bfadc.
-
(2010)
Curr Opin Organ Transplant
, vol.15
, Issue.4
, pp. 427-434
-
-
Safinia, N.1
Sagoo, P.2
Lechler, R.3
Lombardi, G.4
-
4
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol (1995) 155(3):1151-64.
-
(1995)
J Immunol
, vol.155
, Issue.3
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
5
-
-
14844345227
-
CD4+ tregs and immune control
-
Fehervari Z, Sakaguchi S. CD4+ tregs and immune control. J Clin Invest (2004) 114(9):1209-17. doi:10.1172/JCI200423395.
-
(2004)
J Clin Invest
, vol.114
, Issue.9
, pp. 1209-1217
-
-
Fehervari, Z.1
Sakaguchi, S.2
-
6
-
-
84883751545
-
Thymic versus induced regulatory T cells-who regulates the regulators?
-
Povoleri GA, Scotta C, Nova-Lamperti EA, John S, Lombardi G, Afzali B. Thymic versus induced regulatory T cells-who regulates the regulators? Front Immunol (2013) 4:169. doi:10.3389/fimmu.2013.00169.
-
(2013)
Front Immunol
, vol.4
, pp. 169
-
-
Povoleri, G.A.1
Scotta, C.2
Nova-Lamperti, E.A.3
John, S.4
Lombardi, G.5
Afzali, B.6
-
7
-
-
0028037782
-
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
-
Chen Y, Kuchroo VK, Inobe J, Hafler DA, Weiner HL. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science (1994) 265(5176):1237-40. doi:10.1126/science.7520605.
-
(1994)
Science
, vol.265
, Issue.5176
, pp. 1237-1240
-
-
Chen, Y.1
Kuchroo, V.K.2
Inobe, J.3
Hafler, D.A.4
Weiner, H.L.5
-
8
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, de Vries JE, et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature (1997) 389(6652):737-42. doi:10.1038/39614.
-
(1997)
Nature
, vol.389
, Issue.6652
, pp. 737-742
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
de Vries, J.E.6
-
9
-
-
0037018104
-
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)-and Th2-inducing cytokines
-
Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, Savelkoul HF, et al. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)-and Th2-inducing cytokines. J Exp Med (2002) 195(5):603-16. doi:10.1084/jem.20011629.
-
(2002)
J Exp Med
, vol.195
, Issue.5
, pp. 603-616
-
-
Barrat, F.J.1
Cua, D.J.2
Boonstra, A.3
Richards, D.F.4
Crain, C.5
Savelkoul, H.F.6
-
10
-
-
0035339884
-
IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells
-
Levings MK, Sangregorio R, Galbiati F, Squadrone S, de Waal Malefyt R, Roncarolo MG. IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells. J Immunol (2001) 166(9):5530-9. doi:10.4049/jimmunol.166.9.5530.
-
(2001)
J Immunol
, vol.166
, Issue.9
, pp. 5530-5539
-
-
Levings, M.K.1
Sangregorio, R.2
Galbiati, F.3
Squadrone, S.4
de Waal Malefyt, R.5
Roncarolo, M.G.6
-
11
-
-
34547788180
-
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
-
Coombes JL, Siddiqui KR, Arancibia-Carcamo CV, Hall J, Sun CM, Belkaid Y, et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med (2007) 204(8):1757-64. doi:10.1084/jem.20070590.
-
(2007)
J Exp Med
, vol.204
, Issue.8
, pp. 1757-1764
-
-
Coombes, J.L.1
Siddiqui, K.R.2
Arancibia-Carcamo, C.V.3
Hall, J.4
Sun, C.M.5
Belkaid, Y.6
-
12
-
-
84878966545
-
Regulatory cells and transplantation tolerance
-
Cobbold SP, Waldmann H. Regulatory cells and transplantation tolerance. Cold Spring Harb Perspect Med (2013) 3:a015545. doi:10.1101/cshperspect.a015545.
-
(2013)
Cold Spring Harb Perspect Med
, vol.3
-
-
Cobbold, S.P.1
Waldmann, H.2
-
13
-
-
84867901322
-
Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo
-
Yadav M, Louvet C, Davini D, Gardner JM, Martinez-Llordella M, Bailey-Bucktrout S, et al. Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo. J Exp Med (2012) 209(10):1713-22. doi:10.1084/jem.20120822.
-
(2012)
J Exp Med
, vol.209
, Issue.10
, pp. 1713-1722
-
-
Yadav, M.1
Louvet, C.2
Davini, D.3
Gardner, J.M.4
Martinez-Llordella, M.5
Bailey-Bucktrout, S.6
-
14
-
-
84867899425
-
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
-
Weiss JM, Bilate AM, Gobert M, Ding Y, Curotto de Lafaille MA, Parkhurst CN, et al. Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells. J Exp Med (2012) 209(10):1723-42. doi:10.1084/jem.20120914.
-
(2012)
J Exp Med
, vol.209
, Issue.10
, pp. 1723-1742
-
-
Weiss, J.M.1
Bilate, A.M.2
Gobert, M.3
Ding, Y.4
Curotto de Lafaille, M.A.5
Parkhurst, C.N.6
-
15
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science (2003) 299(5609):1057-61. doi:10.1126/science.1079490.
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
16
-
-
33847125247
-
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
-
Wan YY, Flavell RA. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature (2007) 445(7129):766-70. doi:10.1038/nature05479.
-
(2007)
Nature
, vol.445
, Issue.7129
, pp. 766-770
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
17
-
-
58849118836
-
Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?
-
Huehn J, Polansky JK, Hamann A. Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage? Nat Rev Immunol (2009) 9(2):83-9. doi:10.1038/nri2474.
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.2
, pp. 83-89
-
-
Huehn, J.1
Polansky, J.K.2
Hamann, A.3
-
18
-
-
33745817085
-
CD127 expression inversely correlates with Foxp3 and suppressive function of human CD4+ T reg cells
-
Liu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S, et al. CD127 expression inversely correlates with Foxp3 and suppressive function of human CD4+ T reg cells. J Exp Med (2006) 203(7):1701-11. doi:10.1084/jem.20060772.
-
(2006)
J Exp Med
, vol.203
, Issue.7
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
Szot, G.L.4
Lee, M.R.5
Zhu, S.6
-
19
-
-
66949171924
-
Functional delineation and differentiation dynamics of human CD4+ T cells expressing the Foxp3 transcription factor
-
Miyara M, Yoshioka Y, Kitoh A, Shima T, Wing K, Niwa A, et al. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the Foxp3 transcription factor. Immunity (2009) 30(6):899-911. doi:10.1016/j.immuni.2009.03.019.
-
(2009)
Immunity
, vol.30
, Issue.6
, pp. 899-911
-
-
Miyara, M.1
Yoshioka, Y.2
Kitoh, A.3
Shima, T.4
Wing, K.5
Niwa, A.6
-
20
-
-
77952754636
-
Different proliferative potential and migratory characteristics of human CD4+ regulatory T cells that express either CD45RA or CD45RO
-
Booth NJ, McQuaid AJ, Sobande T, Kissane S, Agius E, Jackson SE, et al. Different proliferative potential and migratory characteristics of human CD4+ regulatory T cells that express either CD45RA or CD45RO. J Immunol (2010) 184(8):4317-26. doi:10.4049/jimmunol.0903781.
-
(2010)
J Immunol
, vol.184
, Issue.8
, pp. 4317-4326
-
-
Booth, N.J.1
McQuaid, A.J.2
Sobande, T.3
Kissane, S.4
Agius, E.5
Jackson, S.E.6
-
21
-
-
84881527926
-
CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner
-
Afzali B, Mitchell PJ, Edozie FC, Povoleri GA, Dowson SE, Demandt L, et al. CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner. Eur J Immunol (2013) 43(8):2043-54. doi:10.1002/eji.201243296.
-
(2013)
Eur J Immunol
, vol.43
, Issue.8
, pp. 2043-2054
-
-
Afzali, B.1
Mitchell, P.J.2
Edozie, F.C.3
Povoleri, G.A.4
Dowson, S.E.5
Demandt, L.6
-
22
-
-
84877275454
-
CD161 defines the subset of FoxP3+ T cells capable of producing proinflammatory cytokines
-
Pesenacker AM, Bending D, Ursu S, Wu Q, Nistala K, Wedderburn LR. CD161 defines the subset of FoxP3+ T cells capable of producing proinflammatory cytokines. Blood (2013) 121(14):2647-58. doi:10.1182/blood-2012-08-443473.
-
(2013)
Blood
, vol.121
, Issue.14
, pp. 2647-2658
-
-
Pesenacker, A.M.1
Bending, D.2
Ursu, S.3
Wu, Q.4
Nistala, K.5
Wedderburn, L.R.6
-
23
-
-
84861766132
-
Naturally occurring regulatory T cells: markers, mechanisms, and manipulation
-
Schmetterer KG, Neunkirchner A, Pickl WF. Naturally occurring regulatory T cells: markers, mechanisms, and manipulation. FASEB J (2012) 26(6):2253-76. doi:10.1096/fj.11-193672.
-
(2012)
FASEB J
, vol.26
, Issue.6
, pp. 2253-2276
-
-
Schmetterer, K.G.1
Neunkirchner, A.2
Pickl, W.F.3
-
24
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read S, Malmstrom V, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med (2000) 192(2):295-302. doi:10.1084/jem.192.2.295.
-
(2000)
J Exp Med
, vol.192
, Issue.2
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
25
-
-
79955529454
-
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4
-
Qureshi OS, Zheng Y, Nakamura K, Attridge K, Manzotti C, Schmidt EM, et al. Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science (2011) 332(6029):600-3. doi:10.1126/science.1202947.
-
(2011)
Science
, vol.332
, Issue.6029
, pp. 600-603
-
-
Qureshi, O.S.1
Zheng, Y.2
Nakamura, K.3
Attridge, K.4
Manzotti, C.5
Schmidt, E.M.6
-
26
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
Takahashi T, Tagami T, Yamazaki S, Uede T, Shimizu J, Sakaguchi N, et al. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med (2000) 192(2):303-10. doi:10.1084/jem.192.2.303.
-
(2000)
J Exp Med
, vol.192
, Issue.2
, pp. 303-310
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
-
27
-
-
15444363794
-
T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells
-
Fahlen L, Read S, Gorelik L, Hurst SD, Coffman RL, Flavell RA, et al. T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. J Exp Med (2005) 201(5):737-46. doi:10.1084/jem.20040685.
-
(2005)
J Exp Med
, vol.201
, Issue.5
, pp. 737-746
-
-
Fahlen, L.1
Read, S.2
Gorelik, L.3
Hurst, S.D.4
Coffman, R.L.5
Flavell, R.A.6
-
28
-
-
0029956024
-
A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells
-
Powrie F, Carlino J, Leach MW, Mauze S, Coffman RL. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J Exp Med (1996) 183(6):2669-74. doi:10.1084/jem.183.6.2669.
-
(1996)
J Exp Med
, vol.183
, Issue.6
, pp. 2669-2674
-
-
Powrie, F.1
Carlino, J.2
Leach, M.W.3
Mauze, S.4
Coffman, R.L.5
-
29
-
-
0035869432
-
IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
-
Hara M, Kingsley CI, Niimi M, Read S, Turvey SE, Bushell AR, et al. IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J Immunol (2001) 166(6):3789-96. doi:10.4049/jimmunol.166.6.3789.
-
(2001)
J Immunol
, vol.166
, Issue.6
, pp. 3789-3796
-
-
Hara, M.1
Kingsley, C.I.2
Niimi, M.3
Read, S.4
Turvey, S.E.5
Bushell, A.R.6
-
30
-
-
36549030784
-
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
-
Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature (2007) 450(7169):566-9. doi:10.1038/nature06306.
-
(2007)
Nature
, vol.450
, Issue.7169
, pp. 566-569
-
-
Collison, L.W.1
Workman, C.J.2
Kuo, T.T.3
Boyd, K.4
Wang, Y.5
Vignali, K.M.6
-
31
-
-
13544271161
-
Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
-
Gondek DC, Lu LF, Quezada SA, Sakaguchi S, Noelle RJ. Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J Immunol (2005) 174(4):1783-6. doi:10.4049/jimmunol.174.4.1783.
-
(2005)
J Immunol
, vol.174
, Issue.4
, pp. 1783-1786
-
-
Gondek, D.C.1
Lu, L.F.2
Quezada, S.A.3
Sakaguchi, S.4
Noelle, R.J.5
-
32
-
-
5644238762
-
Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells
-
Grossman WJ, Verbsky JW, Tollefsen BL, Kemper C, Atkinson JP, Ley TJ. Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. Blood (2004) 104(9):2840-8. doi:10.1182/blood-2004-03-0859.
-
(2004)
Blood
, vol.104
, Issue.9
, pp. 2840-2848
-
-
Grossman, W.J.1
Verbsky, J.W.2
Tollefsen, B.L.3
Kemper, C.4
Atkinson, J.P.5
Ley, T.J.6
-
33
-
-
34250351459
-
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
-
Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, et al. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med (2007) 204(6):1257-65. doi:10.1084/jem.20062512.
-
(2007)
J Exp Med
, vol.204
, Issue.6
, pp. 1257-1265
-
-
Deaglio, S.1
Dwyer, K.M.2
Gao, W.3
Friedman, D.4
Usheva, A.5
Erat, A.6
-
34
-
-
73349127157
-
CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis
-
Fletcher JM, Lonergan R, Costelloe L, Kinsella K, Moran B, O'Farrelly C, et al. CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis. J Immunol (2009) 183(11):7602-10. doi:10.4049/jimmunol.0901881.
-
(2009)
J Immunol
, vol.183
, Issue.11
, pp. 7602-7610
-
-
Fletcher, J.M.1
Lonergan, R.2
Costelloe, L.3
Kinsella, K.4
Moran, B.5
O'Farrelly, C.6
-
35
-
-
0037364976
-
Regulatory T cells in transplantation tolerance
-
Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol (2003) 3(3):199-210. doi:10.1038/nri1027.
-
(2003)
Nat Rev Immunol
, vol.3
, Issue.3
, pp. 199-210
-
-
Wood, K.J.1
Sakaguchi, S.2
-
36
-
-
13544258633
-
Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation
-
Hanash AM, Levy RB. Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation. Blood (2005) 105(4):1828-36. doi:10.1182/blood-2004-08-3213.
-
(2005)
Blood
, vol.105
, Issue.4
, pp. 1828-1836
-
-
Hanash, A.M.1
Levy, R.B.2
-
37
-
-
2542496868
-
Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes
-
Joffre O, Gorsse N, Romagnoli P, Hudrisier D, van Meerwijk JP. Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes. Blood (2004) 103(11):4216-21. doi:10.1182/blood-2004-01-0005.
-
(2004)
Blood
, vol.103
, Issue.11
, pp. 4216-4221
-
-
Joffre, O.1
Gorsse, N.2
Romagnoli, P.3
Hudrisier, D.4
van Meerwijk, J.P.5
-
38
-
-
0036498560
-
Tracking the immunoregulatory mechanisms active during allograft tolerance
-
Sanchez-Fueyo A, Weber M, Domenig C, Strom TB, Zheng XX. Tracking the immunoregulatory mechanisms active during allograft tolerance. J Immunol (2002) 168(5):2274-81. doi:10.4049/jimmunol.168.5.2274.
-
(2002)
J Immunol
, vol.168
, Issue.5
, pp. 2274-2281
-
-
Sanchez-Fueyo, A.1
Weber, M.2
Domenig, C.3
Strom, T.B.4
Zheng, X.X.5
-
39
-
-
51749100624
-
Regulatory T cells after organ transplantation: where does their action take place?
-
Dijke IE, Weimar W, Baan CC. Regulatory T cells after organ transplantation: where does their action take place? Hum Immunol (2008) 69(7):389-98. doi:10.1016/j.humimm.2008.05.006.
-
(2008)
Hum Immunol
, vol.69
, Issue.7
, pp. 389-398
-
-
Dijke, I.E.1
Weimar, W.2
Baan, C.C.3
-
40
-
-
0027538467
-
The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice
-
Auchincloss H Jr, Lee R, Shea S, Markowitz JS, Grusby MJ, Glimcher LH. The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice. Proc Natl Acad Sci U S A (1993) 90(8):3373-7. doi:10.1073/pnas.90.8.3373.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, Issue.8
, pp. 3373-3377
-
-
Auchincloss, H.1
Lee, R.2
Shea, S.3
Markowitz, J.S.4
Grusby, M.J.5
Glimcher, L.H.6
-
41
-
-
0032400989
-
Linked suppression of skin graft rejection can operate through indirect recognition
-
Wise MP, Bemelman F, Cobbold SP, Waldmann H. Linked suppression of skin graft rejection can operate through indirect recognition. J Immunol (1998) 161(11):5813-6.
-
(1998)
J Immunol
, vol.161
, Issue.11
, pp. 5813-5816
-
-
Wise, M.P.1
Bemelman, F.2
Cobbold, S.P.3
Waldmann, H.4
-
42
-
-
0042441104
-
Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation
-
Quezada SA, Fuller B, Jarvinen LZ, Gonzalez M, Blazar BR, Rudensky AY, et al. Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation. Blood (2003) 102(5):1920-6. doi:10.1182/blood-2003-02-0586.
-
(2003)
Blood
, vol.102
, Issue.5
, pp. 1920-1926
-
-
Quezada, S.A.1
Fuller, B.2
Jarvinen, L.Z.3
Gonzalez, M.4
Blazar, B.R.5
Rudensky, A.Y.6
-
43
-
-
34447295692
-
CD4+CD25+Foxp3+ indirect alloreactive T cells from renal transplant patients suppress both the direct and indirect pathways of allorecognition
-
Spadafora-Ferreira M, Caldas C, Fae KC, Marrero I, Monteiro SM, Lin-Wang HT, et al. CD4+CD25+Foxp3+ indirect alloreactive T cells from renal transplant patients suppress both the direct and indirect pathways of allorecognition. Scand J Immunol (2007) 66(2-3):352-61. doi:10.1111/j.1365-3083.2007.01976.x.
-
(2007)
Scand J Immunol
, vol.66
, Issue.2-3
, pp. 352-361
-
-
Spadafora-Ferreira, M.1
Caldas, C.2
Fae, K.C.3
Marrero, I.4
Monteiro, S.M.5
Lin-Wang, H.T.6
-
44
-
-
0035889926
-
Recipient MHC class II expression is required to achieve long-term survival of murine cardiac allografts after costimulatory blockade
-
Yamada A, Chandraker A, Laufer TM, Gerth AJ, Sayegh MH, Auchincloss H Jr. Recipient MHC class II expression is required to achieve long-term survival of murine cardiac allografts after costimulatory blockade. J Immunol (2001) 167(10):5522-6. doi:10.4049/jimmunol.167.10.5522.
-
(2001)
J Immunol
, vol.167
, Issue.10
, pp. 5522-5526
-
-
Yamada, A.1
Chandraker, A.2
Laufer, T.M.3
Gerth, A.J.4
Sayegh, M.H.5
Auchincloss, H.6
-
45
-
-
33846214275
-
In vitro-expanded donor alloantigen-specific CD4+CD25+ regulatory T cells promote experimental transplantation tolerance
-
Golshayan D, Jiang S, Tsang J, Garin MI, Mottet C, Lechler RI. In vitro-expanded donor alloantigen-specific CD4+CD25+ regulatory T cells promote experimental transplantation tolerance. Blood (2007) 109(2):827-35. doi:10.1182/blood-2006-05-025460.
-
(2007)
Blood
, vol.109
, Issue.2
, pp. 827-835
-
-
Golshayan, D.1
Jiang, S.2
Tsang, J.3
Garin, M.I.4
Mottet, C.5
Lechler, R.I.6
-
46
-
-
68649106176
-
Indefinite mouse heart allograft survival in recipient treated with CD4(+)CD25(+) regulatory T cells with indirect allospecificity and short term immunosuppression
-
Tsang JY, Tanriver Y, Jiang S, Leung E, Ratnasothy K, Lombardi G, et al. Indefinite mouse heart allograft survival in recipient treated with CD4(+)CD25(+) regulatory T cells with indirect allospecificity and short term immunosuppression. Transpl Immunol (2009) 21(4):203-9. doi:10.1016/j.trim.2009.05.003.
-
(2009)
Transpl Immunol
, vol.21
, Issue.4
, pp. 203-209
-
-
Tsang, J.Y.1
Tanriver, Y.2
Jiang, S.3
Leung, E.4
Ratnasothy, K.5
Lombardi, G.6
-
47
-
-
38049020656
-
Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes
-
Joffre O, Santolaria T, Calise D, Al Saati T, Hudrisier D, Romagnoli P, et al. Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes. Nat Med (2008) 14(1):88-92. doi:10.1038/nm1688.
-
(2008)
Nat Med
, vol.14
, Issue.1
, pp. 88-92
-
-
Joffre, O.1
Santolaria, T.2
Calise, D.3
Al Saati, T.4
Hudrisier, D.5
Romagnoli, P.6
-
48
-
-
77954539326
-
In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells
-
Nadig SN, Wieckiewicz J, Wu DC, Warnecke G, Zhang W, Luo S, et al. In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells. Nat Med (2010) 16(7):809-13. doi:10.1038/nm.2154.
-
(2010)
Nat Med
, vol.16
, Issue.7
, pp. 809-813
-
-
Nadig, S.N.1
Wieckiewicz, J.2
Wu, D.C.3
Warnecke, G.4
Zhang, W.5
Luo, S.6
-
49
-
-
84896922177
-
Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rgammanull mice
-
Xiao F, Ma L, Zhao M, Huang G, Mirenda V, Dorling A, et al. Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rgammanull mice. PLoS One (2014) 9(3):e90387. doi:10.1371/journal.pone.0090387.
-
(2014)
PLoS One
, vol.9
, Issue.3
-
-
Xiao, F.1
Ma, L.2
Zhao, M.3
Huang, G.4
Mirenda, V.5
Dorling, A.6
-
50
-
-
78650835204
-
Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized mouse model
-
Issa F, Hester J, Goto R, Nadig SN, Goodacre TE, Wood K. Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized mouse model. Transplantation (2010) 90(12):1321-7. doi:10.1097/TP.0b013e3181ff8772.
-
(2010)
Transplantation
, vol.90
, Issue.12
, pp. 1321-1327
-
-
Issa, F.1
Hester, J.2
Goto, R.3
Nadig, S.N.4
Goodacre, T.E.5
Wood, K.6
-
51
-
-
84886092766
-
Ex vivo expanded human regulatory T cells can prolong survival of a human islet allograft in a humanized mouse model
-
Wu DC, Hester J, Nadig SN, Zhang W, Trzonkowski P, Gray D, et al. Ex vivo expanded human regulatory T cells can prolong survival of a human islet allograft in a humanized mouse model. Transplantation (2013) 96(8):707-16. doi:10.1097/TP.0b013e31829fa271.
-
(2013)
Transplantation
, vol.96
, Issue.8
, pp. 707-716
-
-
Wu, D.C.1
Hester, J.2
Nadig, S.N.3
Zhang, W.4
Trzonkowski, P.5
Gray, D.6
-
52
-
-
33846630040
-
Humanized mice in translational biomedical research
-
Shultz LD, Ishikawa F, Greiner DL. Humanized mice in translational biomedical research. Nat Rev Immunol (2007) 7(2):118-30. doi:10.1038/nri2017.
-
(2007)
Nat Rev Immunol
, vol.7
, Issue.2
, pp. 118-130
-
-
Shultz, L.D.1
Ishikawa, F.2
Greiner, D.L.3
-
53
-
-
79956288367
-
Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells
-
Sagoo P, Ali N, Garg G, Nestle FO, Lechler RI, Lombardi G. Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells. Sci Transl Med (2011) 3(83):83ra42. doi:10.1126/scitranslmed.3002076.
-
(2011)
Sci Transl Med
, vol.3
, Issue.83
-
-
Sagoo, P.1
Ali, N.2
Garg, G.3
Nestle, F.O.4
Lechler, R.I.5
Lombardi, G.6
-
54
-
-
0141461418
-
CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
-
Edinger M, Hoffmann P, Ermann J, Drago K, Fathman CG, Strober S, et al. CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat Med (2003) 9(9):1144-50. doi:10.1038/nm915.
-
(2003)
Nat Med
, vol.9
, Issue.9
, pp. 1144-1150
-
-
Edinger, M.1
Hoffmann, P.2
Ermann, J.3
Drago, K.4
Fathman, C.G.5
Strober, S.6
-
55
-
-
0346690399
-
Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
-
Trenado A, Charlotte F, Fisson S, Yagello M, Klatzmann D, Salomon BL, et al. Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. J Clin Invest (2003) 112(11):1688-96. doi:10.1172/JCI17702.
-
(2003)
J Clin Invest
, vol.112
, Issue.11
, pp. 1688-1696
-
-
Trenado, A.1
Charlotte, F.2
Fisson, S.3
Yagello, M.4
Klatzmann, D.5
Salomon, B.L.6
-
56
-
-
78751696183
-
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics
-
Brunstein CG, Miller JS, Cao Q, McKenna DH, Hippen KL, Curtsinger J, et al. Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics. Blood (2011) 117(3):1061-70. doi:10.1182/blood-2010-07-293795.
-
(2011)
Blood
, vol.117
, Issue.3
, pp. 1061-1070
-
-
Brunstein, C.G.1
Miller, J.S.2
Cao, Q.3
McKenna, D.H.4
Hippen, K.L.5
Curtsinger, J.6
-
57
-
-
79953809817
-
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
-
Di Ianni M, Falzetti F, Carotti A, Terenzi A, Castellino F, Bonifacio E, et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood (2011) 117(14):3921-8. doi:10.1182/blood-2010-10-311894.
-
(2011)
Blood
, vol.117
, Issue.14
, pp. 3921-3928
-
-
Di Ianni, M.1
Falzetti, F.2
Carotti, A.3
Terenzi, A.4
Castellino, F.5
Bonifacio, E.6
-
58
-
-
70249122695
-
First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127-T regulatory cells
-
Trzonkowski P, Bieniaszewska M, Juscinska J, Dobyszuk A, Krzystyniak A, Marek N, et al. First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127-T regulatory cells. Clin Immunol (2009) 133(1):22-6. doi:10.1016/j.clim.2009.06.001.
-
(2009)
Clin Immunol
, vol.133
, Issue.1
, pp. 22-26
-
-
Trzonkowski, P.1
Bieniaszewska, M.2
Juscinska, J.3
Dobyszuk, A.4
Krzystyniak, A.5
Marek, N.6
-
59
-
-
52049118092
-
Clinical grade Treg: GMP isolation, improvement of purity by CD127 depletion, Treg expansion, and Treg cryopreservation
-
Peters JH, Preijers FW, Woestenenk R, Hilbrands LB, Koenen HJ, Joosten I. Clinical grade Treg: GMP isolation, improvement of purity by CD127 depletion, Treg expansion, and Treg cryopreservation. PLoS One (2008) 3(9):e3161. doi:10.1371/journal.pone.0003161.
-
(2008)
PLoS One
, vol.3
, Issue.9
-
-
Peters, J.H.1
Preijers, F.W.2
Woestenenk, R.3
Hilbrands, L.B.4
Koenen, H.J.5
Joosten, I.6
-
60
-
-
62749201002
-
Expansion of human regulatory T-cells from patients with type 1 diabetes
-
Putnam AL, Brusko TM, Lee MR, Liu W, Szot GL, Ghosh T, et al. Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes (2009) 58(3):652-62. doi:10.2337/db08-1168.
-
(2009)
Diabetes
, vol.58
, Issue.3
, pp. 652-662
-
-
Putnam, A.L.1
Brusko, T.M.2
Lee, M.R.3
Liu, W.4
Szot, G.L.5
Ghosh, T.6
-
61
-
-
33845491455
-
Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion
-
Hoffmann P, Eder R, Boeld TJ, Doser K, Piseshka B, Andreesen R, et al. Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion. Blood (2006) 108(13):4260-7. doi:10.1182/blood-2006-06-027409.
-
(2006)
Blood
, vol.108
, Issue.13
, pp. 4260-4267
-
-
Hoffmann, P.1
Eder, R.2
Boeld, T.J.3
Doser, K.4
Piseshka, B.5
Andreesen, R.6
-
62
-
-
65449141433
-
Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation
-
Hoffmann P, Boeld TJ, Eder R, Huehn J, Floess S, Wieczorek G, et al. Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation. Eur J Immunol (2009) 39(4):1088-97. doi:10.1002/eji.200838904.
-
(2009)
Eur J Immunol
, vol.39
, Issue.4
, pp. 1088-1097
-
-
Hoffmann, P.1
Boeld, T.J.2
Eder, R.3
Huehn, J.4
Floess, S.5
Wieczorek, G.6
-
63
-
-
34548755672
-
DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells
-
Baron U, Floess S, Wieczorek G, Baumann K, Grutzkau A, Dong J, et al. DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells. Eur J Immunol (2007) 37(9):2378-89. doi:10.1002/eji.200737594.
-
(2007)
Eur J Immunol
, vol.37
, Issue.9
, pp. 2378-2389
-
-
Baron, U.1
Floess, S.2
Wieczorek, G.3
Baumann, K.4
Grutzkau, A.5
Dong, J.6
-
64
-
-
78149408519
-
Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells
-
Polansky JK, Schreiber L, Thelemann C, Ludwig L, Kruger M, Baumgrass R, et al. Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells. J Mol Med (2010) 88(10):1029-40. doi:10.1007/s00109-010-0642-1.
-
(2010)
J Mol Med
, vol.88
, Issue.10
, pp. 1029-1040
-
-
Polansky, J.K.1
Schreiber, L.2
Thelemann, C.3
Ludwig, L.4
Kruger, M.5
Baumgrass, R.6
-
65
-
-
76749133610
-
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
-
Zheng Y, Josefowicz S, Chaudhry A, Peng XP, Forbush K, Rudensky AY. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature (2010) 463(7282):808-12. doi:10.1038/nature08750.
-
(2010)
Nature
, vol.463
, Issue.7282
, pp. 808-812
-
-
Zheng, Y.1
Josefowicz, S.2
Chaudhry, A.3
Peng, X.P.4
Forbush, K.5
Rudensky, A.Y.6
-
66
-
-
46749138596
-
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
-
Yang XO, Nurieva R, Martinez GJ, Kang HS, Chung Y, Pappu BP, et al. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity (2008) 29(1):44-56. doi:10.1016/j.immuni.2008.05.007.
-
(2008)
Immunity
, vol.29
, Issue.1
, pp. 44-56
-
-
Yang, X.O.1
Nurieva, R.2
Martinez, G.J.3
Kang, H.S.4
Chung, Y.5
Pappu, B.P.6
-
67
-
-
69049107358
-
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
-
Zhou X, Bailey-Bucktrout SL, Jeker LT, Penaranda C, Martinez-Llordella M, Ashby M, et al. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nat Immunol (2009) 10(9):1000-7. doi:10.1038/ni.1774.
-
(2009)
Nat Immunol
, vol.10
, Issue.9
, pp. 1000-1007
-
-
Zhou, X.1
Bailey-Bucktrout, S.L.2
Jeker, L.T.3
Penaranda, C.4
Martinez-Llordella, M.5
Ashby, M.6
-
68
-
-
70449532980
-
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
-
Oldenhove G, Bouladoux N, Wohlfert EA, Hall JA, Chou D, Dos Santos L, et al. Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity (2009) 31(5):772-86. doi:10.1016/j.immuni.2009.10.001.
-
(2009)
Immunity
, vol.31
, Issue.5
, pp. 772-786
-
-
Oldenhove, G.1
Bouladoux, N.2
Wohlfert, E.A.3
Hall, J.A.4
Chou, D.5
Dos Santos, L.6
-
69
-
-
78650124721
-
Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice
-
Sharma MD, Hou DY, Baban B, Koni PA, He Y, Chandler PR, et al. Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice. Immunity (2010) 33(6):942-54. doi:10.1016/j.immuni.2010.11.022.
-
(2010)
Immunity
, vol.33
, Issue.6
, pp. 942-954
-
-
Sharma, M.D.1
Hou, D.Y.2
Baban, B.3
Koni, P.A.4
He, Y.5
Chandler, P.R.6
-
70
-
-
60549115770
-
Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity
-
Komatsu N, Mariotti-Ferrandiz ME, Wang Y, Malissen B, Waldmann H, Hori S. Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci U S A (2009) 106(6):1903-8. doi:10.1073/pnas.0811556106.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.6
, pp. 1903-1908
-
-
Komatsu, N.1
Mariotti-Ferrandiz, M.E.2
Wang, Y.3
Malissen, B.4
Waldmann, H.5
Hori, S.6
-
71
-
-
84930019397
-
Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease
-
Canavan JB, Scotta C, Vossenkamper A, Goldberg R, Elder MJ, Shoval I, et al. Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease. Gut (2015) 1-11. doi:10.1136/gutjnl-2014-306919.
-
(2015)
Gut
, pp. 1-11
-
-
Canavan, J.B.1
Scotta, C.2
Vossenkamper, A.3
Goldberg, R.4
Elder, M.J.5
Shoval, I.6
-
72
-
-
33745813929
-
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
-
Seddiki N, Santner-Nanan B, Martinson J, Zaunders J, Sasson S, Landay A, et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med (2006) 203(7):1693-700. doi:10.1084/jem.20060468.
-
(2006)
J Exp Med
, vol.203
, Issue.7
, pp. 1693-1700
-
-
Seddiki, N.1
Santner-Nanan, B.2
Martinson, J.3
Zaunders, J.4
Sasson, S.5
Landay, A.6
-
73
-
-
84908501047
-
Purification of regulatory T cells with the use of a fully enclosed high-speed microfluidic system
-
Hulspas R, Villa-KomaroffL, Koksal E, Etienne K, Rogers P, Tuttle M, et al. Purification of regulatory T cells with the use of a fully enclosed high-speed microfluidic system. Cytotherapy (2014) 16(10):1384-9. doi:10.1016/j.jcyt.2014.05.016.
-
(2014)
Cytotherapy
, vol.16
, Issue.10
, pp. 1384-1389
-
-
Hulspas, R.1
Villa-Komaroff, L.2
Koksal, E.3
Etienne, K.4
Rogers, P.5
Tuttle, M.6
-
74
-
-
0035806323
-
Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
-
Levings MK, Sangregorio R, Roncarolo MG. Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J Exp Med (2001) 193(11):1295-302. doi:10.1084/jem.193.11.1295.
-
(2001)
J Exp Med
, vol.193
, Issue.11
, pp. 1295-1302
-
-
Levings, M.K.1
Sangregorio, R.2
Roncarolo, M.G.3
-
75
-
-
65349159281
-
Immunoregulatory functions of mTOR inhibition
-
Thomson AW, Turnquist HR, Raimondi G. Immunoregulatory functions of mTOR inhibition. Nat Rev Immunol (2009) 9(5):324-37. doi:10.1038/nri2546.
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.5
, pp. 324-337
-
-
Thomson, A.W.1
Turnquist, H.R.2
Raimondi, G.3
-
76
-
-
38049177784
-
Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells
-
Zeiser R, Leveson-Gower DB, Zambricki EA, Kambham N, Beilhack A, Loh J, et al. Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells. Blood (2008) 111(1):453-62. doi:10.1182/blood-2007-06-094482.
-
(2008)
Blood
, vol.111
, Issue.1
, pp. 453-462
-
-
Zeiser, R.1
Leveson-Gower, D.B.2
Zambricki, E.A.3
Kambham, N.4
Beilhack, A.5
Loh, J.6
-
77
-
-
20444373376
-
Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
-
Battaglia M, Stabilini A, Roncarolo MG. Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. Blood (2005) 105(12):4743-8. doi:10.1182/blood-2004-10-3932.
-
(2005)
Blood
, vol.105
, Issue.12
, pp. 4743-4748
-
-
Battaglia, M.1
Stabilini, A.2
Roncarolo, M.G.3
-
78
-
-
66949173728
-
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment
-
Delgoffe GM, Kole TP, Zheng Y, Zarek PE, Matthews KL, Xiao B, et al. The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity (2009) 30(6):832-44. doi:10.1016/j.immuni.2009.04.014.
-
(2009)
Immunity
, vol.30
, Issue.6
, pp. 832-844
-
-
Delgoffe, G.M.1
Kole, T.P.2
Zheng, Y.3
Zarek, P.E.4
Matthews, K.L.5
Xiao, B.6
-
79
-
-
84864463754
-
Low-dose rapamycin treatment increases the ability of human regulatory T cells to inhibit transplant arteriosclerosis in vivo
-
Hester J, Schiopu A, Nadig SN, Wood KJ. Low-dose rapamycin treatment increases the ability of human regulatory T cells to inhibit transplant arteriosclerosis in vivo. Am J Transplant (2012) 12(8):2008-16. doi:10.1111/j.1600-6143.2012.04065.x.
-
(2012)
Am J Transplant
, vol.12
, Issue.8
, pp. 2008-2016
-
-
Hester, J.1
Schiopu, A.2
Nadig, S.N.3
Wood, K.J.4
-
80
-
-
33947249410
-
Regulatory T cells and T cell depletion: role of immunosuppressive drugs
-
Noris M, Casiraghi F, Todeschini M, Cravedi P, Cugini D, Monteferrante G, et al. Regulatory T cells and T cell depletion: role of immunosuppressive drugs. J Am Soc Nephrol (2007) 18(3):1007-18. doi:10.1681/ASN.2006101143.
-
(2007)
J Am Soc Nephrol
, vol.18
, Issue.3
, pp. 1007-1018
-
-
Noris, M.1
Casiraghi, F.2
Todeschini, M.3
Cravedi, P.4
Cugini, D.5
Monteferrante, G.6
-
81
-
-
33747889822
-
Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients
-
Segundo DS, Ruiz JC, Izquierdo M, Fernandez-Fresnedo G, Gomez-Alamillo C, Merino R, et al. Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients. Transplantation (2006) 82(4):550-7. doi:10.1097/01.tp.0000229473.95202.50.
-
(2006)
Transplantation
, vol.82
, Issue.4
, pp. 550-557
-
-
Segundo, D.S.1
Ruiz, J.C.2
Izquierdo, M.3
Fernandez-Fresnedo, G.4
Gomez-Alamillo, C.5
Merino, R.6
-
82
-
-
44449100271
-
Cutting edge: foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin
-
Basu S, Golovina T, Mikheeva T, June CH, Riley JL. Cutting edge: foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin. J Immunol (2008) 180(9):5794-8. doi:10.4049/jimmunol.180.9.5794.
-
(2008)
J Immunol
, vol.180
, Issue.9
, pp. 5794-5798
-
-
Basu, S.1
Golovina, T.2
Mikheeva, T.3
June, C.H.4
Riley, J.L.5
-
83
-
-
80052376898
-
Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells
-
Tresoldi E, Dell'albani I, Stabilini A, Jofra T, Valle A, Gagliani N, et al. Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells. Haematologica (2011) 96(9):1357-65. doi:10.3324/haematol.2011.041483.
-
(2011)
Haematologica
, vol.96
, Issue.9
, pp. 1357-1365
-
-
Tresoldi, E.1
Dell'albani, I.2
Stabilini, A.3
Jofra, T.4
Valle, A.5
Gagliani, N.6
-
84
-
-
79251589897
-
Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells
-
Golovina TN, Mikheeva T, Brusko TM, Blazar BR, Bluestone JA, Riley JL. Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells. PLoS One (2011) 6(1):e15868. doi:10.1371/journal.pone.0015868.
-
(2011)
PLoS One
, vol.6
, Issue.1
-
-
Golovina, T.N.1
Mikheeva, T.2
Brusko, T.M.3
Blazar, B.R.4
Bluestone, J.A.5
Riley, J.L.6
-
85
-
-
84880968811
-
Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+Foxp3+ Treg subpopulations
-
Scotta C, Esposito M, Fazekasova H, Fanelli G, Edozie FC, Ali N, et al. Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+Foxp3+ Treg subpopulations. Haematologica (2012). doi:10.3324/haematol.2012.074088.
-
(2012)
Haematologica
-
-
Scotta, C.1
Esposito, M.2
Fazekasova, H.3
Fanelli, G.4
Edozie, F.C.5
Ali, N.6
-
86
-
-
77953808089
-
Rag2-/-gamma-chain-/-mice as hosts for human vessel transplantation and allogeneic human leukocyte reconstitution
-
Abele-Ohl S, Leis M, Mahmoudian S, Weyand M, Stamminger T, Ensminger SM. Rag2-/-gamma-chain-/-mice as hosts for human vessel transplantation and allogeneic human leukocyte reconstitution. Transpl Immunol (2010) 23(1-2):59-64. doi:10.1016/j.trim.2010.04.003.
-
(2010)
Transpl Immunol
, vol.23
, Issue.1-2
, pp. 59-64
-
-
Abele-Ohl, S.1
Leis, M.2
Mahmoudian, S.3
Weyand, M.4
Stamminger, T.5
Ensminger, S.M.6
-
87
-
-
84919628900
-
Ex vivo-expanded but not in vitro-induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the Foxp3 regulatory T cell-specific demethylated region
-
Rossetti M, Spreafico R, Saidin S, Chua C, Moshref M, Leong JY, et al. Ex vivo-expanded but not in vitro-induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the Foxp3 regulatory T cell-specific demethylated region. J Immunol (2015) 194(1):113-24. doi:10.4049/jimmunol.1401145.
-
(2015)
J Immunol
, vol.194
, Issue.1
, pp. 113-124
-
-
Rossetti, M.1
Spreafico, R.2
Saidin, S.3
Chua, C.4
Moshref, M.5
Leong, J.Y.6
-
88
-
-
77952314065
-
From carrot to clinic: an overview of the retinoic acid signaling pathway
-
Theodosiou M, Laudet V, Schubert M. From carrot to clinic: an overview of the retinoic acid signaling pathway. Cell Mol Life Sci (2010) 67(9):1423-45. doi:10.1007/s00018-010-0268-z.
-
(2010)
Cell Mol Life Sci
, vol.67
, Issue.9
, pp. 1423-1445
-
-
Theodosiou, M.1
Laudet, V.2
Schubert, M.3
-
89
-
-
79952740974
-
Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha
-
Hall JA, Cannons JL, Grainger JR, Dos Santos LM, Hand TW, Naik S, et al. Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha. Immunity (2011) 34(3):435-47. doi:10.1016/j.immuni.2011.03.003.
-
(2011)
Immunity
, vol.34
, Issue.3
, pp. 435-447
-
-
Hall, J.A.1
Cannons, J.L.2
Grainger, J.R.3
Dos Santos, L.M.4
Hand, T.W.5
Naik, S.6
-
90
-
-
34447503805
-
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
-
Mucida D, Park Y, Kim G, Turovskaya O, Scott I, Kronenberg M, et al. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science (2007) 317(5835):256-60. doi:10.1126/science.1145697.
-
(2007)
Science
, vol.317
, Issue.5835
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
Turovskaya, O.4
Scott, I.5
Kronenberg, M.6
-
91
-
-
38949164425
-
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
-
Elias KM, Laurence A, Davidson TS, Stephens G, Kanno Y, Shevach EM, et al. Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood (2008) 111(3):1013-20. doi:10.1182/blood-2007-06-096438.
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1013-1020
-
-
Elias, K.M.1
Laurence, A.2
Davidson, T.S.3
Stephens, G.4
Kanno, Y.5
Shevach, E.M.6
-
92
-
-
64049110576
-
Retinoic acid can directly promote TGF-beta-mediated Foxp3(+) Treg cell conversion of naive T cells
-
Mucida D, Pino-Lagos K, Kim G, Nowak E, Benson MJ, Kronenberg M, et al. Retinoic acid can directly promote TGF-beta-mediated Foxp3(+) Treg cell conversion of naive T cells. Immunity (2009) 30(4):471-2. doi:10.1016/j.immuni.2009.03.008.
-
(2009)
Immunity
, vol.30
, Issue.4
, pp. 471-472
-
-
Mucida, D.1
Pino-Lagos, K.2
Kim, G.3
Nowak, E.4
Benson, M.J.5
Kronenberg, M.6
-
93
-
-
63549146201
-
Low-dose of tacrolimus favors the induction of functional CD4(+)CD25(+)FoxP3(+) regulatory T cells in solid-organ transplantation
-
Wang Z, Shi B, Jin H, Xiao L, Chen Y, Qian Y. Low-dose of tacrolimus favors the induction of functional CD4(+)CD25(+)FoxP3(+) regulatory T cells in solid-organ transplantation. Int Immunopharmacol (2009) 9(5):564-9. doi:10.1016/j.intimp.2009.01.029.
-
(2009)
Int Immunopharmacol
, vol.9
, Issue.5
, pp. 564-569
-
-
Wang, Z.1
Shi, B.2
Jin, H.3
Xiao, L.4
Chen, Y.5
Qian, Y.6
-
94
-
-
84906308941
-
Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions
-
Lu L, Lan Q, Li Z, Zhou X, Gu J, Li Q, et al. Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions. Proc Natl Acad Sci U S A (2014) 111(33):E3432-40. doi:10.1073/pnas.1408780111.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.33
, pp. E3432-E3440
-
-
Lu, L.1
Lan, Q.2
Li, Z.3
Zhou, X.4
Gu, J.5
Li, Q.6
-
95
-
-
35748934494
-
Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells
-
Kang SG, Lim HW, Andrisani OM, Broxmeyer HE, Kim CH. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol (2007) 179(6):3724-33. doi:10.4049/jimmunol.179.6.3724.
-
(2007)
J Immunol
, vol.179
, Issue.6
, pp. 3724-3733
-
-
Kang, S.G.1
Lim, H.W.2
Andrisani, O.M.3
Broxmeyer, H.E.4
Kim, C.H.5
-
96
-
-
34447282494
-
Vitamin A regulation of gene expression: molecular mechanism of a prototype gene
-
McGrane MM. Vitamin A regulation of gene expression: molecular mechanism of a prototype gene. J Nutr Biochem (2007) 18(8):497-508. doi:10.1016/j.jnutbio.2006.10.006.
-
(2007)
J Nutr Biochem
, vol.18
, Issue.8
, pp. 497-508
-
-
McGrane, M.M.1
-
97
-
-
80052744481
-
All-trans retinoic acid promotes TGF-beta-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus
-
Lu L, Ma J, Li Z, Lan Q, Chen M, Liu Y, et al. All-trans retinoic acid promotes TGF-beta-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus. PLoS One (2011) 6(9):e24590. doi:10.1371/journal.pone.0024590.
-
(2011)
PLoS One
, vol.6
, Issue.9
-
-
Lu, L.1
Ma, J.2
Li, Z.3
Lan, Q.4
Chen, M.5
Liu, Y.6
-
98
-
-
84923437687
-
IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance
-
Basu R, Whitley SK, Bhaumik S, Zindl CL, Schoeb TR, Benveniste EN, et al. IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance. Nat Immunol (2015) 16(3):286-95. doi:10.1038/ni.3099.
-
(2015)
Nat Immunol
, vol.16
, Issue.3
, pp. 286-295
-
-
Basu, R.1
Whitley, S.K.2
Bhaumik, S.3
Zindl, C.L.4
Schoeb, T.R.5
Benveniste, E.N.6
-
99
-
-
84864478443
-
Serum 25-dihydroxyvitamin D levels correlate with CD4(+)Foxp3(+) T-cell numbers in moderate/severe asthma
-
Chambers ES, Nanzer AM, Richards DF, Ryanna K, Freeman AT, Timms PM, et al. Serum 25-dihydroxyvitamin D levels correlate with CD4(+)Foxp3(+) T-cell numbers in moderate/severe asthma. J Allergy Clin Immunol (2012) 130(2):542-4. doi:10.1016/j.jaci.2012.04.022.
-
(2012)
J Allergy Clin Immunol
, vol.130
, Issue.2
, pp. 542-544
-
-
Chambers, E.S.1
Nanzer, A.M.2
Richards, D.F.3
Ryanna, K.4
Freeman, A.T.5
Timms, P.M.6
-
100
-
-
84861666390
-
Effects of ultraviolet light on human serum 25-hydroxyvitamin D and systemic immune function
-
Milliken SV, Wassall H, Lewis BJ, Logie J, Barker RN, Macdonald H, et al. Effects of ultraviolet light on human serum 25-hydroxyvitamin D and systemic immune function. J Allergy Clin Immunol (2012) 129(6):1554-61. doi:10.1016/j.jaci.2012.03.001.
-
(2012)
J Allergy Clin Immunol
, vol.129
, Issue.6
, pp. 1554-1561
-
-
Milliken, S.V.1
Wassall, H.2
Lewis, B.J.3
Logie, J.4
Barker, R.N.5
Macdonald, H.6
-
101
-
-
68949140898
-
Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis
-
Smolders J, Thewissen M, Peelen E, Menheere P, Tervaert JW, Damoiseaux J, et al. Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis. PLoS One (2009) 4(8):e6635. doi:10.1371/journal.pone.0006635.
-
(2009)
PLoS One
, vol.4
, Issue.8
-
-
Smolders, J.1
Thewissen, M.2
Peelen, E.3
Menheere, P.4
Tervaert, J.W.5
Damoiseaux, J.6
-
102
-
-
84867202982
-
The role of 1alpha,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+ and IL-10+ CD4+ T cells
-
Urry Z, Chambers ES, Xystrakis E, Dimeloe S, Richards DF, Gabrysova L, et al. The role of 1alpha,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+ and IL-10+ CD4+ T cells. Eur J Immunol (2012) 42(10):2697-708. doi:10.1002/eji.201242370.
-
(2012)
Eur J Immunol
, vol.42
, Issue.10
, pp. 2697-2708
-
-
Urry, Z.1
Chambers, E.S.2
Xystrakis, E.3
Dimeloe, S.4
Richards, D.F.5
Gabrysova, L.6
-
103
-
-
84904865500
-
1alpha,25-dihydroxyvitamin D3 in combination with transforming growth factor-beta increases the frequency of Foxp3(+) regulatory T cells through preferential expansion and usage of interleukin-2
-
Chambers ES, Suwannasaen D, Mann EH, Urry Z, Richards DF, Lertmemongkolchai G, et al. 1alpha,25-dihydroxyvitamin D3 in combination with transforming growth factor-beta increases the frequency of Foxp3(+) regulatory T cells through preferential expansion and usage of interleukin-2. Immunology (2014) 143(1):52-60. doi:10.1111/imm.12289.
-
(2014)
Immunology
, vol.143
, Issue.1
, pp. 52-60
-
-
Chambers, E.S.1
Suwannasaen, D.2
Mann, E.H.3
Urry, Z.4
Richards, D.F.5
Lertmemongkolchai, G.6
-
104
-
-
84886786872
-
Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation
-
Putnam AL, Safinia N, Medvec A, Laszkowska M, Wray M, Mintz MA, et al. Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation. Am J Transplant (2013) 13(11):3010-20. doi:10.1111/ajt.12433.
-
(2013)
Am J Transplant
, vol.13
, Issue.11
, pp. 3010-3020
-
-
Putnam, A.L.1
Safinia, N.2
Medvec, A.3
Laszkowska, M.4
Wray, M.5
Mintz, M.A.6
-
105
-
-
48249098901
-
Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy
-
Peters JH, Hilbrands LB, Koenen HJ, Joosten I. Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy. PLoS One (2008) 3(5):e2233. doi:10.1371/journal.pone.0002233.
-
(2008)
PLoS One
, vol.3
, Issue.5
-
-
Peters, J.H.1
Hilbrands, L.B.2
Koenen, H.J.3
Joosten, I.4
-
106
-
-
70349336184
-
Direct expansion of human allospecific FoxP3+CD4+ regulatory T cells with allogeneic B cells for therapeutic application
-
Chen LC, Delgado JC, Jensen PE, Chen X. Direct expansion of human allospecific FoxP3+CD4+ regulatory T cells with allogeneic B cells for therapeutic application. J Immunol (2009) 183(6):4094-102. doi:10.4049/jimmunol.0901081.
-
(2009)
J Immunol
, vol.183
, Issue.6
, pp. 4094-4102
-
-
Chen, L.C.1
Delgado, J.C.2
Jensen, P.E.3
Chen, X.4
-
107
-
-
84861039302
-
IL-5 promotes induction of antigen-specific CD4+CD25+ T regulatory cells that suppress autoimmunity
-
Tran GT, Hodgkinson SJ, Carter NM, Verma ND, Plain KM, Boyd R, et al. IL-5 promotes induction of antigen-specific CD4+CD25+ T regulatory cells that suppress autoimmunity. Blood (2012) 119(19):4441-50. doi:10.1182/blood-2011-12-396101.
-
(2012)
Blood
, vol.119
, Issue.19
, pp. 4441-4450
-
-
Tran, G.T.1
Hodgkinson, S.J.2
Carter, N.M.3
Verma, N.D.4
Plain, K.M.5
Boyd, R.6
-
108
-
-
0037087202
-
Role of mitochondria in alcoholic liver injury
-
Adachi M, Ishii H. Role of mitochondria in alcoholic liver injury. Free Radic Biol Med (2002) 32(6):487-91. doi:10.1016/S0891-5849(02)00740-2.
-
(2002)
Free Radic Biol Med
, vol.32
, Issue.6
, pp. 487-491
-
-
Adachi, M.1
Ishii, H.2
-
109
-
-
55249113014
-
Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells
-
Tu W, Lau YL, Zheng J, Liu Y, Chan PL, Mao H, et al. Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells. Blood (2008) 112(6):2554-62. doi:10.1182/blood-2008-04-152041.
-
(2008)
Blood
, vol.112
, Issue.6
, pp. 2554-2562
-
-
Tu, W.1
Lau, Y.L.2
Zheng, J.3
Liu, Y.4
Chan, P.L.5
Mao, H.6
-
110
-
-
75949123497
-
CD40-activated B cells are more potent than immature dendritic cells to induce and expand CD4(+) regulatory T cells
-
Zheng J, Liu Y, Lau YL, Tu W. CD40-activated B cells are more potent than immature dendritic cells to induce and expand CD4(+) regulatory T cells. Cell Mol Immunol (2010) 7(1):44-50. doi:10.1038/cmi.2009.103.
-
(2010)
Cell Mol Immunol
, vol.7
, Issue.1
, pp. 44-50
-
-
Zheng, J.1
Liu, Y.2
Lau, Y.L.3
Tu, W.4
-
111
-
-
77955380678
-
Human antigen-specific regulatory T cells generated by T cell receptor gene transfer
-
Brusko TM, Koya RC, Zhu S, Lee MR, Putnam AL, McClymont SA, et al. Human antigen-specific regulatory T cells generated by T cell receptor gene transfer. PLoS One (2010) 5(7):e11726. doi:10.1371/journal.pone.0011726.
-
(2010)
PLoS One
, vol.5
, Issue.7
-
-
Brusko, T.M.1
Koya, R.C.2
Zhu, S.3
Lee, M.R.4
Putnam, A.L.5
McClymont, S.A.6
-
112
-
-
84890104932
-
Use of gene-modified regulatory T-cells to control autoimmune and alloimmune pathology: is now the right time?
-
Jethwa H, Adami AA, Maher J. Use of gene-modified regulatory T-cells to control autoimmune and alloimmune pathology: is now the right time? Clin Immunol (2014) 150(1):51-63. doi:10.1016/j.clim.2013.11.004.
-
(2014)
Clin Immunol
, vol.150
, Issue.1
, pp. 51-63
-
-
Jethwa, H.1
Adami, A.A.2
Maher, J.3
-
113
-
-
84861542408
-
CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery
-
Fransson M, Piras E, Burman J, Nilsson B, Essand M, Lu B, et al. CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery. J Neuroinflammation (2012) 9:112. doi:10.1186/1742-2094-9-112.
-
(2012)
J Neuroinflammation
, vol.9
, pp. 112
-
-
Fransson, M.1
Piras, E.2
Burman, J.3
Nilsson, B.4
Essand, M.5
Lu, B.6
-
114
-
-
84899946297
-
Suppression of murine colitis and its associated cancer by carcinoembryonic antigen-specific regulatory T cells
-
Blat D, Zigmond E, Alteber Z, Waks T, Eshhar Z. Suppression of murine colitis and its associated cancer by carcinoembryonic antigen-specific regulatory T cells. Mol Ther (2014) 22(5):1018-28. doi:10.1038/mt.2014.41.
-
(2014)
Mol Ther
, vol.22
, Issue.5
, pp. 1018-1028
-
-
Blat, D.1
Zigmond, E.2
Alteber, Z.3
Waks, T.4
Eshhar, Z.5
-
115
-
-
0141678976
-
Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo
-
Jiang S, Camara N, Lombardi G, Lechler RI. Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo. Blood (2003) 102(6):2180-6. doi:10.1182/blood-2003-04-1164.
-
(2003)
Blood
, vol.102
, Issue.6
, pp. 2180-2186
-
-
Jiang, S.1
Camara, N.2
Lombardi, G.3
Lechler, R.I.4
-
116
-
-
81555214616
-
Ex vivo expansion of human tregs specific for alloantigens presented directly or indirectly
-
Veerapathran A, Pidala J, Beato F, Yu XZ, Anasetti C. Ex vivo expansion of human tregs specific for alloantigens presented directly or indirectly. Blood (2011) 118(20):5671-80. doi:10.1182/blood-2011-02-337097.
-
(2011)
Blood
, vol.118
, Issue.20
, pp. 5671-5680
-
-
Veerapathran, A.1
Pidala, J.2
Beato, F.3
Yu, X.Z.4
Anasetti, C.5
-
117
-
-
55849142632
-
Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice
-
Tsang JY, Tanriver Y, Jiang S, Xue SA, Ratnasothy K, Chen D, et al. Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice. J Clin Invest (2008) 118(11):3619-28. doi:10.1172/JCI33185.
-
(2008)
J Clin Invest
, vol.118
, Issue.11
, pp. 3619-3628
-
-
Tsang, J.Y.1
Tanriver, Y.2
Jiang, S.3
Xue, S.A.4
Ratnasothy, K.5
Chen, D.6
-
118
-
-
84899144218
-
Therapy of type 1 diabetes with CD4(+)CD25(high)CD127-regulatory T cells prolongs survival of pancreatic islets-results of one year follow-up
-
Marek-Trzonkowska N, Mysliwiec M, Dobyszuk A, Grabowska M, Derkowska I, Juscinska J, et al. Therapy of type 1 diabetes with CD4(+)CD25(high)CD127-regulatory T cells prolongs survival of pancreatic islets-results of one year follow-up. Clin Immunol (2014) 153(1):23-30. doi:10.1016/j.clim.2014.03.016.
-
(2014)
Clin Immunol
, vol.153
, Issue.1
, pp. 23-30
-
-
Marek-Trzonkowska, N.1
Mysliwiec, M.2
Dobyszuk, A.3
Grabowska, M.4
Derkowska, I.5
Juscinska, J.6
-
119
-
-
84941271625
-
Induction of operational tolerance by cell therapy using donor Ag-pulsed tregs in living donorliver transplantation
-
Yamashita K, Goto R, Zaitsu M, Agatsu AN, Oura T, Watanabe M, et al. Induction of operational tolerance by cell therapy using donor Ag-pulsed tregs in living donorliver transplantation. World Transplant Congress San Francisco (2014) 98:871-905. doi:10.1097/01.tp.0000452138.48155.71.
-
(2014)
World Transplant Congress San Francisco
, vol.98
, pp. 871-905
-
-
Yamashita, K.1
Goto, R.2
Zaitsu, M.3
Agatsu, A.N.4
Oura, T.5
Watanabe, M.6
-
120
-
-
0345476290
-
Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance
-
Wells AD, Li XC, Li Y, Walsh MC, Zheng XX, Wu Z, et al. Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. Nat Med (1999) 5(11):1303-7. doi:10.1038/8466.
-
(1999)
Nat Med
, vol.5
, Issue.11
, pp. 1303-1307
-
-
Wells, A.D.1
Li, X.C.2
Li, Y.3
Walsh, M.C.4
Zheng, X.X.5
Wu, Z.6
-
121
-
-
38149050594
-
Ex vivo-expanded natural CD4+CD25+ regulatory T cells synergize with host T-cell depletion to promote long-term survival of allografts
-
Xia G, He J, Leventhal JR. Ex vivo-expanded natural CD4+CD25+ regulatory T cells synergize with host T-cell depletion to promote long-term survival of allografts. Am J Transplant (2008) 8(2):298-306. doi:10.1111/j.1600-6143.2007.02088.x.
-
(2008)
Am J Transplant
, vol.8
, Issue.2
, pp. 298-306
-
-
Xia, G.1
He, J.2
Leventhal, J.R.3
-
122
-
-
0037120053
-
Interleukin 2 signaling is required for CD4(+) regulatory T cell function
-
Furtado GC, Curotto de Lafaille MA, Kutchukhidze N, Lafaille JJ. Interleukin 2 signaling is required for CD4(+) regulatory T cell function. J Exp Med (2002) 196(6):851-7. doi:10.1084/jem.20020190.
-
(2002)
J Exp Med
, vol.196
, Issue.6
, pp. 851-857
-
-
Furtado, G.C.1
Curotto de Lafaille, M.A.2
Kutchukhidze, N.3
Lafaille, J.J.4
-
123
-
-
33745633856
-
Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production
-
Zeiser R, Nguyen VH, Beilhack A, Buess M, Schulz S, Baker J, et al. Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production. Blood (2006) 108(1):390-9. doi:10.1182/blood-2006-01-0329.
-
(2006)
Blood
, vol.108
, Issue.1
, pp. 390-399
-
-
Zeiser, R.1
Nguyen, V.H.2
Beilhack, A.3
Buess, M.4
Schulz, S.5
Baker, J.6
-
124
-
-
22144475453
-
Differential effect of calcineurin inhibitors, anti-CD25 antibodies and rapamycin on the induction of FOXP3 in human T cells
-
Baan CC, van der Mast BJ, Klepper M, Mol WM, Peeters AM, Korevaar SS, et al. Differential effect of calcineurin inhibitors, anti-CD25 antibodies and rapamycin on the induction of FOXP3 in human T cells. Transplantation (2005) 80(1):110-7. doi:10.1097/01.TP.0000164142.98167.4B.
-
(2005)
Transplantation
, vol.80
, Issue.1
, pp. 110-117
-
-
Baan, C.C.1
van der Mast, B.J.2
Klepper, M.3
Mol, W.M.4
Peeters, A.M.5
Korevaar, S.S.6
-
125
-
-
31544482746
-
Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells
-
Coenen JJ, Koenen HJ, van Rijssen E, Hilbrands LB, Joosten I. Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells. Blood (2006) 107(3):1018-23. doi:10.1182/blood-2005-07-3032.
-
(2006)
Blood
, vol.107
, Issue.3
, pp. 1018-1023
-
-
Coenen, J.J.1
Koenen, H.J.2
van Rijssen, E.3
Hilbrands, L.B.4
Joosten, I.5
-
126
-
-
84870570002
-
Differing effects of rapamycin or calcineurin inhibitor on T-regulatory cells in pediatric liver and kidney transplant recipients
-
Akimova T, Kamath BM, Goebel JW, Meyers KE, Rand EB, Hawkins A, et al. Differing effects of rapamycin or calcineurin inhibitor on T-regulatory cells in pediatric liver and kidney transplant recipients. Am J Transplant (2012) 12(12):3449-61. doi:10.1111/j.1600-6143.2012.04269.x.
-
(2012)
Am J Transplant
, vol.12
, Issue.12
, pp. 3449-3461
-
-
Akimova, T.1
Kamath, B.M.2
Goebel, J.W.3
Meyers, K.E.4
Rand, E.B.5
Hawkins, A.6
-
127
-
-
84864531704
-
Immunosuppressive drugs on inducing Ag-specific CD4(+)CD25(+)Foxp3(+) Treg cells during immune response in vivo
-
Wu T, Zhang L, Xu K, Sun C, Lei T, Peng J, et al. Immunosuppressive drugs on inducing Ag-specific CD4(+)CD25(+)Foxp3(+) Treg cells during immune response in vivo. Transpl Immunol (2012) 27(1):30-8. doi:10.1016/j.trim.2012.05.001.
-
(2012)
Transpl Immunol
, vol.27
, Issue.1
, pp. 30-38
-
-
Wu, T.1
Zhang, L.2
Xu, K.3
Sun, C.4
Lei, T.5
Peng, J.6
-
128
-
-
40349092811
-
The epidemiology of glucocorticoid-associated adverse events
-
McDonough AK, Curtis JR, Saag KG. The epidemiology of glucocorticoid-associated adverse events. Curr Opin Rheumatol (2008) 20(2):131-7. doi:10.1097/BOR.0b013e3282f51031.
-
(2008)
Curr Opin Rheumatol
, vol.20
, Issue.2
, pp. 131-137
-
-
McDonough, A.K.1
Curtis, J.R.2
Saag, K.G.3
-
129
-
-
33747414436
-
Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3(+)CD4(+)CD25(+) T regulatory cells in vivo and enhances their capacity to suppress EAE
-
Chen X, Oppenheim JJ, Winkler-Pickett RT, Ortaldo JR, Howard OM. Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3(+)CD4(+)CD25(+) T regulatory cells in vivo and enhances their capacity to suppress EAE. Eur J Immunol (2006) 36(8):2139-49. doi:10.1002/eji.200635873.
-
(2006)
Eur J Immunol
, vol.36
, Issue.8
, pp. 2139-2149
-
-
Chen, X.1
Oppenheim, J.J.2
Winkler-Pickett, R.T.3
Ortaldo, J.R.4
Howard, O.M.5
-
130
-
-
20844432359
-
Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma
-
Karagiannidis C, Akdis M, Holopainen P, Woolley NJ, Hense G, Ruckert B, et al. Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. J Allergy Clin Immunol (2004) 114(6):1425-33. doi:10.1016/j.jaci.2004.07.014.
-
(2004)
J Allergy Clin Immunol
, vol.114
, Issue.6
, pp. 1425-1433
-
-
Karagiannidis, C.1
Akdis, M.2
Holopainen, P.3
Woolley, N.J.4
Hense, G.5
Ruckert, B.6
-
131
-
-
69949189926
-
Glucocorticoid treatment restores the impaired suppressive function of regulatory T cells in patients with relapsing-remitting multiple sclerosis
-
Xu L, Xu Z, Xu M. Glucocorticoid treatment restores the impaired suppressive function of regulatory T cells in patients with relapsing-remitting multiple sclerosis. Clin Exp Immunol (2009) 158(1):26-30. doi:10.1111/j.1365-2249.2009.03987.x.
-
(2009)
Clin Exp Immunol
, vol.158
, Issue.1
, pp. 26-30
-
-
Xu, L.1
Xu, Z.2
Xu, M.3
-
132
-
-
0031570475
-
Corticosteroids inhibit IL-12 production in human monocytes and enhance their capacity to induce IL-4 synthesis in CD4+ lymphocytes
-
Blotta MH, DeKruyffRH, Umetsu DT. Corticosteroids inhibit IL-12 production in human monocytes and enhance their capacity to induce IL-4 synthesis in CD4+ lymphocytes. J Immunol (1997) 158(12):5589-95.
-
(1997)
J Immunol
, vol.158
, Issue.12
, pp. 5589-5595
-
-
Blotta, M.H.1
DeKruyff, R.H.2
Umetsu, D.T.3
-
133
-
-
70249137304
-
Prednisolone treatment induces tolerogenic dendritic cells and a regulatory milieu in myasthenia gravis patients
-
Luther C, Adamopoulou E, Stoeckle C, Brucklacher-Waldert V, Rosenkranz D, Stoltze L, et al. Prednisolone treatment induces tolerogenic dendritic cells and a regulatory milieu in myasthenia gravis patients. J Immunol (2009) 183(2):841-8. doi:10.4049/jimmunol.0802046.
-
(2009)
J Immunol
, vol.183
, Issue.2
, pp. 841-848
-
-
Luther, C.1
Adamopoulou, E.2
Stoeckle, C.3
Brucklacher-Waldert, V.4
Rosenkranz, D.5
Stoltze, L.6
-
134
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L, Ivanov II, Spolski R, Min R, Shenderov K, Egawa T, et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol (2007) 8(9):967-74. doi:10.1038/ni1488.
-
(2007)
Nat Immunol
, vol.8
, Issue.9
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
Min, R.4
Shenderov, K.5
Egawa, T.6
-
135
-
-
33749259809
-
A novel mechanism of action for anti-thymocyte globulin: induction of CD4+CD25+Foxp3+ regulatory T cells
-
Lopez M, Clarkson MR, Albin M, Sayegh MH, Najafian N. A novel mechanism of action for anti-thymocyte globulin: induction of CD4+CD25+Foxp3+ regulatory T cells. J Am Soc Nephrol (2006) 17(10):2844-53. doi:10.1681/ASN.2006050422.
-
(2006)
J Am Soc Nephrol
, vol.17
, Issue.10
, pp. 2844-2853
-
-
Lopez, M.1
Clarkson, M.R.2
Albin, M.3
Sayegh, M.H.4
Najafian, N.5
-
136
-
-
33845915103
-
Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin
-
Strauss L, Whiteside TL, Knights A, Bergmann C, Knuth A, Zippelius A. Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin. J Immunol (2007) 178(1):320-9. doi:10.4049/jimmunol.178.1.320.
-
(2007)
J Immunol
, vol.178
, Issue.1
, pp. 320-329
-
-
Strauss, L.1
Whiteside, T.L.2
Knights, A.3
Bergmann, C.4
Knuth, A.5
Zippelius, A.6
-
137
-
-
34047174849
-
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production
-
Allan SE, Crome SQ, Crellin NK, Passerini L, Steiner TS, Bacchetta R, et al. Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. Int Immunol (2007) 19(4):345-54. doi:10.1093/intimm/dxm014.
-
(2007)
Int Immunol
, vol.19
, Issue.4
, pp. 345-354
-
-
Allan, S.E.1
Crome, S.Q.2
Crellin, N.K.3
Passerini, L.4
Steiner, T.S.5
Bacchetta, R.6
-
138
-
-
33846980131
-
Epigenetic control of the foxp3 locus in regulatory T cells
-
Floess S, Freyer J, Siewert C, Baron U, Olek S, Polansky J, et al. Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol (2007) 5(2):e38. doi:10.1371/journal.pbio.0050038.
-
(2007)
PLoS Biol
, vol.5
, Issue.2
-
-
Floess, S.1
Freyer, J.2
Siewert, C.3
Baron, U.4
Olek, S.5
Polansky, J.6
-
139
-
-
74949115148
-
Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting
-
Sanchez-Abarca LI, Gutierrez-Cosio S, Santamaria C, Caballero-Velazquez T, Blanco B, Herrero-Sanchez C, et al. Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting. Blood (2010) 115(1):107-21. doi:10.1182/blood-2009-03-210393.
-
(2010)
Blood
, vol.115
, Issue.1
, pp. 107-121
-
-
Sanchez-Abarca, L.I.1
Gutierrez-Cosio, S.2
Santamaria, C.3
Caballero-Velazquez, T.4
Blanco, B.5
Herrero-Sanchez, C.6
-
140
-
-
84859582203
-
Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML)
-
Goodyear OC, Dennis M, Jilani NY, Loke J, Siddique S, Ryan G, et al. Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML). Blood (2012) 119(14):3361-9. doi:10.1182/blood-2011-09-377044.
-
(2012)
Blood
, vol.119
, Issue.14
, pp. 3361-3369
-
-
Goodyear, O.C.1
Dennis, M.2
Jilani, N.Y.3
Loke, J.4
Siddique, S.5
Ryan, G.6
-
141
-
-
84863229506
-
Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells
-
Kwon HS, Lim HW, Wu J, Schnolzer M, Verdin E, Ott M. Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells. J Immunol (2012) 188(6):2712-21. doi:10.4049/jimmunol.1100903.
-
(2012)
J Immunol
, vol.188
, Issue.6
, pp. 2712-2721
-
-
Kwon, H.S.1
Lim, H.W.2
Wu, J.3
Schnolzer, M.4
Verdin, E.5
Ott, M.6
-
142
-
-
84855708785
-
Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function
-
Liu Y, Wang L, Han R, Beier UH, Hancock WW. Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function. PLoS One (2012) 7(1):e29035. doi:10.1371/journal.pone.0029035.
-
(2012)
PLoS One
, vol.7
, Issue.1
-
-
Liu, Y.1
Wang, L.2
Han, R.3
Beier, U.H.4
Hancock, W.W.5
-
143
-
-
79952274915
-
Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival
-
Beier UH, Wang L, Bhatti TR, Liu Y, Han R, Ge G, et al. Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival. Mol Cell Biol (2011) 31(5):1022-9. doi:10.1128/MCB.01206-10.
-
(2011)
Mol Cell Biol
, vol.31
, Issue.5
, pp. 1022-1029
-
-
Beier, U.H.1
Wang, L.2
Bhatti, T.R.3
Liu, Y.4
Han, R.5
Ge, G.6
-
144
-
-
78049303465
-
Infectious tolerance: therapeutic potential
-
Kendal AR, Waldmann H. Infectious tolerance: therapeutic potential. Curr Opin Immunol (2010) 22(5):560-5. doi:10.1016/j.coi.2010.08.002.
-
(2010)
Curr Opin Immunol
, vol.22
, Issue.5
, pp. 560-565
-
-
Kendal, A.R.1
Waldmann, H.2
-
145
-
-
51049101255
-
CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner
-
Andersson J, Tran DQ, Pesu M, Davidson TS, Ramsey H, O'Shea JJ, et al. CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner. J Exp Med (2008) 205(9):1975-81. doi:10.1084/jem.20080308.
-
(2008)
J Exp Med
, vol.205
, Issue.9
, pp. 1975-1981
-
-
Andersson, J.1
Tran, D.Q.2
Pesu, M.3
Davidson, T.S.4
Ramsey, H.5
O'Shea, J.J.6
-
146
-
-
79959572627
-
Cutting edge: human regulatory T cells require IL-35 to mediate suppression and infectious tolerance
-
Chaturvedi V, Collison LW, Guy CS, Workman CJ, Vignali DA. Cutting edge: human regulatory T cells require IL-35 to mediate suppression and infectious tolerance. J Immunol (2011) 186(12):6661-6. doi:10.4049/jimmunol.1100315.
-
(2011)
J Immunol
, vol.186
, Issue.12
, pp. 6661-6666
-
-
Chaturvedi, V.1
Collison, L.W.2
Guy, C.S.3
Workman, C.J.4
Vignali, D.A.5
-
147
-
-
80555129271
-
Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance
-
Kendal AR, Chen Y, Regateiro FS, Ma J, Adams E, Cobbold SP, et al. Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance. J Exp Med (2011) 208(10):2043-53. doi:10.1084/jem.20110767.
-
(2011)
J Exp Med
, vol.208
, Issue.10
, pp. 2043-2053
-
-
Kendal, A.R.1
Chen, Y.2
Regateiro, F.S.3
Ma, J.4
Adams, E.5
Cobbold, S.P.6
-
148
-
-
84881372495
-
Transplant tolerance to pancreatic islets is initiated in the graft and sustained in the spleen
-
Gagliani N, Jofra T, Valle A, Stabilini A, Morsiani C, Gregori S, et al. Transplant tolerance to pancreatic islets is initiated in the graft and sustained in the spleen. Am J Transplant (2013) 13(8):1963-75. doi:10.1111/ajt.12333.
-
(2013)
Am J Transplant
, vol.13
, Issue.8
, pp. 1963-1975
-
-
Gagliani, N.1
Jofra, T.2
Valle, A.3
Stabilini, A.4
Morsiani, C.5
Gregori, S.6
-
149
-
-
80054731732
-
In vivo SPECT reporter gene imaging of regulatory T cells
-
Sharif-Paghaleh E, Sunassee K, Tavare R, Ratnasothy K, Koers A, Ali N, et al. In vivo SPECT reporter gene imaging of regulatory T cells. PLoS One (2011) 6(10):e25857. doi:10.1371/journal.pone.0025857.
-
(2011)
PLoS One
, vol.6
, Issue.10
-
-
Sharif-Paghaleh, E.1
Sunassee, K.2
Tavare, R.3
Ratnasothy, K.4
Koers, A.5
Ali, N.6
-
150
-
-
84857646605
-
The role of interleukin-2 during homeostasis and activation of the immune system
-
Boyman O, Sprent J. The role of interleukin-2 during homeostasis and activation of the immune system. Nat Rev Immunol (2012) 12(3):180-90. doi:10.1038/nri3156.
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.3
, pp. 180-190
-
-
Boyman, O.1
Sprent, J.2
-
151
-
-
82555168440
-
Interleukin-2 and regulatory T cells in graft-versus-host disease
-
Koreth J, Matsuoka K, Kim HT, McDonough SM, Bindra B, Alyea EP III, et al. Interleukin-2 and regulatory T cells in graft-versus-host disease. N Engl J Med (2011) 365(22):2055-66. doi:10.1056/NEJMoa1108188.
-
(2011)
N Engl J Med
, vol.365
, Issue.22
, pp. 2055-2066
-
-
Koreth, J.1
Matsuoka, K.2
Kim, H.T.3
McDonough, S.M.4
Bindra, B.5
Alyea, E.P.6
-
152
-
-
78650196293
-
Adoptive cell transfer of T-cell receptor-engineered lymphocytes: lessons from recent modeling
-
Ribas A, Koya RC. Adoptive cell transfer of T-cell receptor-engineered lymphocytes: lessons from recent modeling. Future Oncol (2010) 6(11):1671-3. doi:10.2217/fon.10.137.
-
(2010)
Future Oncol
, vol.6
, Issue.11
, pp. 1671-1673
-
-
Ribas, A.1
Koya, R.C.2
-
153
-
-
77952944052
-
Designing customized cell signalling circuits
-
Lim WA. Designing customized cell signalling circuits. Nat Rev Mol cell Biol (2010) 11(6):393-403. doi:10.1038/nrm2904.
-
(2010)
Nat Rev Mol cell Biol
, vol.11
, Issue.6
, pp. 393-403
-
-
Lim, W.A.1
-
154
-
-
49349095817
-
Clinical-grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene
-
Guillot-Delost M, Cherai M, Hamel Y, Rosenzwajg M, Baillou C, Simonin G, et al. Clinical-grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene. J Gene Med (2008) 10(8):834-46. doi:10.1002/jgm.1220.
-
(2008)
J Gene Med
, vol.10
, Issue.8
, pp. 834-846
-
-
Guillot-Delost, M.1
Cherai, M.2
Hamel, Y.3
Rosenzwajg, M.4
Baillou, C.5
Simonin, G.6
-
155
-
-
34247194881
-
Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy
-
Sato T, Neschadim A, Konrad M, Fowler DH, Lavie A, Medin JA. Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy. Mol Ther (2007) 15(5):962-70. doi:10.1038/mt.sj.6300122.
-
(2007)
Mol Ther
, vol.15
, Issue.5
, pp. 962-970
-
-
Sato, T.1
Neschadim, A.2
Konrad, M.3
Fowler, D.H.4
Lavie, A.5
Medin, J.A.6
-
156
-
-
0036604283
-
Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance
-
Graca L, Thompson S, Lin CY, Adams E, Cobbold SP, Waldmann H. Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance. J Immunol (2002) 168(11):5558-65. doi:10.4049/jimmunol.168.11.5558.
-
(2002)
J Immunol
, vol.168
, Issue.11
, pp. 5558-5565
-
-
Graca, L.1
Thompson, S.2
Lin, C.Y.3
Adams, E.4
Cobbold, S.P.5
Waldmann, H.6
-
157
-
-
84863840517
-
Regulatory T-cell therapy for transplantation: how many cells do we need?
-
Tang Q, Lee K. Regulatory T-cell therapy for transplantation: how many cells do we need? Curr Opin Organ Transplant (2012) 17(4):349-54. doi:10.1097/MOT.0b013e328355a992.
-
(2012)
Curr Opin Organ Transplant
, vol.17
, Issue.4
, pp. 349-354
-
-
Tang, Q.1
Lee, K.2
-
158
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
Tang Q, Henriksen KJ, Bi M, Finger EB, Szot G, Ye J, et al. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med (2004) 199(11):1455-65. doi:10.1084/jem.20040139.
-
(2004)
J Exp Med
, vol.199
, Issue.11
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
-
159
-
-
2942692039
-
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
-
Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM. CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med (2004) 199(11):1467-77. doi:10.1084/jem.20040180.
-
(2004)
J Exp Med
, vol.199
, Issue.11
, pp. 1467-1477
-
-
Tarbell, K.V.1
Yamazaki, S.2
Olson, K.3
Toy, P.4
Steinman, R.M.5
-
160
-
-
34848857054
-
Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance
-
Brouard S, Mansfield E, Braud C, Li L, Giral M, Hsieh SC, et al. Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance. Proc Natl Acad Sci U S A (2007) 104(39):15448-53. doi:10.1073/pnas.0705834104.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.39
, pp. 15448-15453
-
-
Brouard, S.1
Mansfield, E.2
Braud, C.3
Li, L.4
Giral, M.5
Hsieh, S.C.6
-
161
-
-
48749084927
-
Using transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients
-
Martinez-Llordella M, Lozano JJ, Puig-Pey I, Orlando G, Tisone G, Lerut J, et al. Using transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients. J Clin Invest (2008) 118(8):2845-57. doi:10.1172/JCI35342.
-
(2008)
J Clin Invest
, vol.118
, Issue.8
, pp. 2845-2857
-
-
Martinez-Llordella, M.1
Lozano, J.J.2
Puig-Pey, I.3
Orlando, G.4
Tisone, G.5
Lerut, J.6
-
162
-
-
77953209236
-
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans
-
Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, et al. Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest (2010) 120(6):1848-61. doi:10.1172/JCI39922.
-
(2010)
J Clin Invest
, vol.120
, Issue.6
, pp. 1848-1861
-
-
Sagoo, P.1
Perucha, E.2
Sawitzki, B.3
Tomiuk, S.4
Stephens, D.A.5
Miqueu, P.6
-
163
-
-
84867588802
-
High-throughput 13-parameter immunophenotyping identifies shifts in the circulating T-cell compartment following reperfusion in patients with acute myocardial infarction
-
Hoffmann J, Fiser K, Weaver J, Dimmick I, Loeher M, Pircher H, et al. High-throughput 13-parameter immunophenotyping identifies shifts in the circulating T-cell compartment following reperfusion in patients with acute myocardial infarction. PLoS One (2012) 7(10):e47155. doi:10.1371/journal.pone.0047155.
-
(2012)
PLoS One
, vol.7
, Issue.10
-
-
Hoffmann, J.1
Fiser, K.2
Weaver, J.3
Dimmick, I.4
Loeher, M.5
Pircher, H.6
-
164
-
-
79952111603
-
Analysis of the peripheral T-cell repertoire in kidney transplant patients
-
Miqueu P, Degauque N, Guillet M, Giral M, Ruiz C, Pallier A, et al. Analysis of the peripheral T-cell repertoire in kidney transplant patients. Eur J Immunol (2010) 40(11):3280-90. doi:10.1002/eji.201040301.
-
(2010)
Eur J Immunol
, vol.40
, Issue.11
, pp. 3280-3290
-
-
Miqueu, P.1
Degauque, N.2
Guillet, M.3
Giral, M.4
Ruiz, C.5
Pallier, A.6
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