Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma

Journal of Allergy and Clinical Immunology

Volumn 114, Issue 6, 2004, Pages 1425-1433

  Karagiannidis, Christian ^a   Akdis, Mübeccel ^a   Holopainen, Päivi ^a   Woolley, Niina J ^b   Hense, Gabriele ^c   Rückert, Beate ^a   Mantel, Pierre Yves ^a   Menz, Günther ^c   Akdis, Cezmi A ^a   Blaser, Kurt ^a   Schmidt Weber, Carsten B ^a,c  

^a SWISS INSTITUTE OF ALLERGY AND ASTHMA RESEARCH SIAF   (Switzerland)

^b Red Cross Finland   (Finland)

^c Davos Wolfgang ^*  (Switzerland)

Author keywords

cellular differentiation; FOXP3; glucocorticoids; regulatory T cell; severe asthma; T lymphocytes; Tolerance suppression anergy; transcription factors

Indexed keywords

CD4 ANTIGEN; GLUCOCORTICOID; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1;

ALLERGY; ARTICLE; ASTHMA; CELL DIFFERENTIATION; CHROMOSOME XP; CONTROLLED STUDY; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC STRAIN; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; MAJOR CLINICAL STUDY; MEMORY CELL; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; T LYMPHOCYTE; UPREGULATION;

ADULT; ASTHMA; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; IMMUNOGLOBULIN E; INTERLEUKIN-10; MICROSATELLITE REPEATS; MIDDLE AGED; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 20844432359     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2004.07.014     Document Type: Article

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