-
1
-
-
2442484053
-
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi, S. 2004. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22:531-562.
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
2
-
-
0026603775
-
Revisiting and revising suppressor T cells
-
Bloom, B.R., Salgame, P., and Diamond, B. 1992. Revisiting and revising suppressor T cells. Immunol. Today. 13:131-136.
-
(1992)
Immunol. Today
, vol.13
, pp. 131-136
-
-
Bloom, B.R.1
Salgame, P.2
Diamond, B.3
-
3
-
-
0038434099
-
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
-
Gambineri, E., Torgerson, T.R., and Ochs, H.D. 2003. Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr. Opin. Rheumatol. 15:430-435.
-
(2003)
Curr. Opin. Rheumatol.
, vol.15
, pp. 430-435
-
-
Gambineri, E.1
Torgerson, T.R.2
Ochs, H.D.3
-
4
-
-
0035181582
-
Type 1 T regulatory cells
-
Roncarolo, M.G., Bacchetta, R., Bordignon, C., Narula, S., and Levings, M.K. 2001. Type 1 T regulatory cells. Immunol. Rev. 182:68-79.
-
(2001)
Immunol. Rev.
, vol.182
, pp. 68-79
-
-
Roncarolo, M.G.1
Bacchetta, R.2
Bordignon, C.3
Narula, S.4
Levings, M.K.5
-
5
-
-
0035186416
-
Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells
-
Weiner, H.L. 2001. Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells. Immunol. Rev. 182:207-214.
-
(2001)
Immunol. Rev.
, vol.182
, pp. 207-214
-
-
Weiner, H.L.1
-
6
-
-
0037364804
-
Natural versus adaptive regulatory T cells
-
Bluestone, J.A., and Abbas, A.K. 2003. Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 3:253-257.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 253-257
-
-
Bluestone, J.A.1
Abbas, A.K.2
-
7
-
-
0020451946
-
Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis
-
Sakaguchi, S., Takahashi, T., and Nishizuka, Y. 1982. Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis J. Exp. Med. 156:1577-1586.
-
(1982)
J. Exp. Med.
, vol.156
, pp. 1577-1586
-
-
Sakaguchi, S.1
Takahashi, T.2
Nishizuka, Y.3
-
8
-
-
0021997185
-
Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease
-
Sakaguchi, S., Fukuma, K., Kuribayashi, K., and Masuda, T. 1985. Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J. Exp. Med. 161:72-87.
-
(1985)
J. Exp. Med.
, vol.161
, pp. 72-87
-
-
Sakaguchi, S.1
Fukuma, K.2
Kuribayashi, K.3
Masuda, T.4
-
9
-
-
0029788211
-
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
-
Asano, M., Toda, M., Sakaguchi, N., and Sakaguchi. S. 1996. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 184:387-396.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 387-396
-
-
Asano, M.1
Toda, M.2
Sakaguchi, N.3
Sakaguchi, S.4
-
10
-
-
0015908120
-
Spontaneous thyroiditis in thymectomized and irradiated Wistar rats
-
Penhale, W.J., Farmer, A., McKenna, R.P., and Irvine, W.J. 1973. Spontaneous thyroiditis in thymectomized and irradiated Wistar rats. Clin. Exp. Immunol. 15:225-236.
-
(1973)
Clin. Exp. Immunol.
, vol.15
, pp. 225-236
-
-
Penhale, W.J.1
Farmer, A.2
McKenna, R.P.3
Irvine, W.J.4
-
11
-
-
0027509812
-
Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential
-
Fowell, D., and Mason, D. 1993. Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential. J. Exp. Med. 177:627-636.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 627-636
-
-
Fowell, D.1
Mason, D.2
-
12
-
-
0024500755
-
T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice
-
Boitard, C., Yasunami, R., Dardenne, M., and Bach, J.F. 1989. T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice. J. Exp. Med. 169:1669-1680.
-
(1989)
J. Exp. Med.
, vol.169
, pp. 1669-1680
-
-
Boitard, C.1
Yasunami, R.2
Dardenne, M.3
Bach, J.F.4
-
13
-
-
0023267515
-
Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats
-
Greiner, D.L., et al. 1987. Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats. J. Exp. Med. 166:461-475.
-
(1987)
J. Exp. Med.
, vol.166
, pp. 461-475
-
-
Greiner, D.L.1
-
14
-
-
0025572276
-
OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: Prevention by the OX-22low subset
-
Powrie, F., and Mason, D. 1990. OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset. J. Exp. Med. 172:1701-1708.
-
(1990)
J. Exp. Med.
, vol.172
, pp. 1701-1708
-
-
Powrie, F.1
Mason, D.2
-
15
-
-
0027517545
-
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
-
Powrie, F., Leach, M.W., Mauze, S., Caddle, L.B., and Coffman, R.L. 1993. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. Int. Immunol. 5:1461-1471.
-
(1993)
Int. Immunol.
, vol.5
, pp. 1461-1471
-
-
Powrie, F.1
Leach, M.W.2
Mauze, S.3
Caddle, L.B.4
Coffman, R.L.5
-
16
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M., and Toda, M. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155:1151-1164.
-
(1995)
J. Immunol.
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
17
-
-
0033136302
-
Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
-
Itoh, M., et al. 1999. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162:5317-5326.
-
(1999)
J. Immunol.
, vol.162
, pp. 5317-5326
-
-
Itoh, M.1
-
18
-
-
0034141684
-
The third function of the thymus
-
Seddon, B., and Mason, D. 2000. The third function of the thymus. Immunol. Today. 21:95-99.
-
(2000)
Immunol. Today
, vol.21
, pp. 95-99
-
-
Seddon, B.1
Mason, D.2
-
19
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan, M.S., et al. 2001. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat. Immunol. 2:301-306.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
-
20
-
-
0036568942
-
Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
-
Kawahata, K., et al. 2002. Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression. J. Immunol. 168:4399-4405.
-
(2002)
J. Immunol.
, vol.168
, pp. 4399-4405
-
-
Kawahata, K.1
-
21
-
-
0037621729
-
Decreasing the threshold for thymocyte activation biases CD4+ T cells toward a regulatory (CD4+CD25+) lineage
-
Stephens, G.L., and Ignatowicz, L. 2003. Decreasing the threshold for thymocyte activation biases CD4+ T cells toward a regulatory (CD4+CD25+) lineage. Eur. J. Immunol. 33:1282-1291.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 1282-1291
-
-
Stephens, G.L.1
Ignatowicz, L.2
-
22
-
-
2142818492
-
Thymic generation and selection of CD25+CD4+ regulatory T cells: Implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance
-
Sakaguchi, S., et al. 2003. Thymic generation and selection of CD25+CD4+ regulatory T cells: implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance. Novartis Found. Symp. 252:6-16.
-
(2003)
Novartis Found. Symp.
, vol.252
, pp. 6-16
-
-
Sakaguchi, S.1
-
23
-
-
4143066714
-
Recognition of the peripheral self by naturally arising CD25(+) CD4(+) T cell receptors
-
Hsieh, C.S., et al. 2004. Recognition of the peripheral self by naturally arising CD25(+) CD4(+) T cell receptors. Immunity. 21:267-277.
-
(2004)
Immunity
, vol.21
, pp. 267-277
-
-
Hsieh, C.S.1
-
24
-
-
0033682056
-
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
-
Salomon, B., et al. 2000. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity. 12:431-440.
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
-
25
-
-
0035164360
-
Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: A role of CD40 in regulatory T cell development
-
Kumanogoh, A., et al. 2001. Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: a role of CD40 in regulatory T cell development. J. Immunol. 166:353-360.
-
(2001)
J. Immunol.
, vol.166
, pp. 353-360
-
-
Kumanogoh, A.1
-
26
-
-
0036791004
-
Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells
-
Lehmann, J., et al. 2002. Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells. Proc. Natl. Acad. Sci. U. S. A. 99:13031-13036.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 13031-13036
-
-
Lehmann, J.1
-
27
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
Takahashi, T., et al. 2000. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 192:303-310.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
-
28
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read, S., Malmstrom, V., and Powrie, F. 2000. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J. Exp. Med. 192:295-302.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
29
-
-
0036170938
-
Stimulation of CD25(+)CD4(+) regulatory T cells through GITreg breaks immunological self-tolerance
-
Shimizu, J., Yamazaki, S., Takahashi, T., Ishida, Y., and Sakaguchi, S. 2002. Stimulation of CD25(+)CD4(+) regulatory T cells through GITreg breaks immunological self-tolerance. Nat. Immunol. 3:135-142.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 135-142
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
30
-
-
0036195161
-
CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
McHugh, R.S., et al. 2002. CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity. 16:311-323.
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.S.1
-
31
-
-
1642347202
-
Neuropilin-1: A surface marker of regulatory T cells
-
Bruder, D., et al. 2004. Neuropilin-1: a surface marker of regulatory T cells. Eur. J. Immunol. 34:623-630.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 623-630
-
-
Bruder, D.1
-
32
-
-
0035413350
-
CD4+CD25high regulatory cells in human peripheral blood
-
Baecher-Allan, C., Brown, J.A., Freeman, G.J., and Hafler, D.A. 2001. CD4+CD25high regulatory cells in human peripheral blood. J. Immunol. 167:1245-1253.
-
(2001)
J. Immunol.
, vol.167
, pp. 1245-1253
-
-
Baecher-Allan, C.1
Brown, J.A.2
Freeman, G.J.3
Hafler, D.A.4
-
33
-
-
0036839102
-
Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
-
Almeida, A.R., Legrand, N., Papiernik, M., and Freitas, A.A. 2002. Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers. J. Immunol. 169:4850-4860.
-
(2002)
J. Immunol.
, vol.169
, pp. 4850-4860
-
-
Almeida, A.R.1
Legrand, N.2
Papiernik, M.3
Freitas, A.A.4
-
34
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in lL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
-
Malek, T.R., Yu, A., Vincek, V., Scibelli, P., and Kong, L. 2002. CD4 regulatory T cells prevent lethal autoimmunity in lL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity. 17:167-178.
-
(2002)
Immunity
, vol.17
, pp. 167-178
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
35
-
-
7144259082
-
Regulatory CD4 T cells: Expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
-
Papiernik, M., de Moraes, M.L., Pontoux, C., Vasseur, F., and Penit, C. 1998. Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency. Int. Immunol. 10:371-378.
-
(1998)
Int. Immunol.
, vol.10
, pp. 371-378
-
-
Papiernik, M.1
De Moraes, M.L.2
Pontoux, C.3
Vasseur, F.4
Penit, C.5
-
36
-
-
2942532501
-
Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells
-
Kanamaru, F., et al. 2004. Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells. J. Immunol. 172:7306-7314.
-
(2004)
J. Immunol.
, vol.172
, pp. 7306-7314
-
-
Kanamaru, F.1
-
37
-
-
6344279933
-
Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells
-
Stephens, G.L. et al. 2004. Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells. J. Immunol. 173:5008-5020.
-
(2004)
J. Immunol.
, vol.173
, pp. 5008-5020
-
-
Stephens, G.L.1
-
38
-
-
0345598872
-
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells
-
Tone, M., et al. 2003. Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells. Proc. Natl. Acad. Sci. U. S. A. 100:15059-15064.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 15059-15064
-
-
Tone, M.1
-
39
-
-
0028171297
-
CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse
-
Blair, P.J., et al. 1994. CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse. J. Immunol. 153:3764-3774.
-
(1994)
J. Immunol.
, vol.153
, pp. 3764-3774
-
-
Blair, P.J.1
-
40
-
-
0026043866
-
Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: Potential model for thymic education
-
Godfrey, V.L., Wilkinson, J.E., Rinchik, E.M., and Russell, L.B. 1991. Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education. Proc. Natl. Acad. Sci. U. S. A. 88:5528-5532.
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 5528-5532
-
-
Godfrey, V.L.1
Wilkinson, J.E.2
Rinchik, E.M.3
Russell, L.B.4
-
41
-
-
0025317650
-
The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome
-
Lyon, M.F., Peters, J., Glenister, P.H., Ball, S., and Wright, E. 1990. The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome. Proc. Natl. Acad. Sci. U. S. A. 87:2433-2437.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 2433-2437
-
-
Lyon, M.F.1
Peters, J.2
Glenister, P.H.3
Ball, S.4
Wright, E.5
-
42
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow, M.E., et al. 2001. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27:68-73.
-
(2001)
Nat. Genet.
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
-
43
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-Iinked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett, C.L., et al. 2001. The immune dysregulation, polyendocrinopathy, enteropathy, X-Iinked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 27:20-21.
-
(2001)
Nat. Genet.
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
-
44
-
-
0035813231
-
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation
-
Schubert, L.A., Jeffery, E., Zhang, Y., Ramsdell, F., and Ziegler, S.F. 2001. Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J. Biol. Chem. 276:37672-37679.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37672-37679
-
-
Schubert, L.A.1
Jeffery, E.2
Zhang, Y.3
Ramsdell, F.4
Ziegler, S.F.5
-
45
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri, R., Cox, T., Yasayko, S.A., and Ramsdell, F. 2003. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4:337-342.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
46
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T, and Sakaguchi, S. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science. 299:1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
47
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J.D., Gavin, M.A., and Rudensky, A.Y. 2003. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4:330-336.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
48
-
-
19344374571
-
HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
-
Oswald-Richter, K., et al. 2004. HIV infection of naturally occurring and genetically reprogrammed human regulatory T-Cells. PLoS Biol. 2:E198.
-
(2004)
PLoS Biol.
, vol.2
-
-
Oswald-Richter, K.1
-
49
-
-
8644280556
-
Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
-
doi: 10.1182/blood-2004-01-0365
-
Weiss, L., et al. 2004. Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood. doi: 10.1182/blood-2004-01-0365.
-
(2004)
Blood
-
-
Weiss, L.1
-
50
-
-
0346969978
-
- T cells
-
doi:10.1172/JCI200319441
-
- T cells. J. Clin. Invest. 112:1437-1443. doi:10.1172/JCI200319441.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1437-1443
-
-
Walker, M.R.1
-
51
-
-
8344275995
-
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells
-
In press
-
Yagi, H., et al. 2004. Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int. Immunol. In press.
-
(2004)
Int. Immunol.
-
-
Yagi, H.1
-
52
-
-
2942733256
-
Human CD25+ regulatory T cells: Two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4+ T helper cells
-
Stassen, M., et al. 2004. Human CD25+ regulatory T cells: two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4+ T helper cells. Eur. J. Immunol. 34:1303-1311.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1303-1311
-
-
Stassen, M.1
-
53
-
-
1642410432
-
Induction of FOXP3-expressing regulatory CD4pos T cells by human mature autologous dendritic cells
-
Verhasselt, V., et al. 2004. Induction of FOXP3-expressing regulatory CD4pos T cells by human mature autologous dendritic cells. Eur. J. Immunol. 34:762-772.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 762-772
-
-
Verhasselt, V.1
-
54
-
-
0036379775
-
X-chromosome inactivation analysis in a female carrier of FOXP3 mutation
-
Tommasini, A., et al. 2002. X-chromosome inactivation analysis in a female carrier of FOXP3 mutation. Clin. Exp. Immunol. 130:127-130.
-
(2002)
Clin. Exp. Immunol.
, vol.130
, pp. 127-130
-
-
Tommasini, A.1
-
55
-
-
0037243827
-
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
-
Maloy, K.J., et al. 2003. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. 197:111-119.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 111-119
-
-
Maloy, K.J.1
-
56
-
-
0347480215
-
CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells
-
Serra, P., et al. 2003. CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells. Immunity. 19:877-889.
-
(2003)
Immunity
, vol.19
, pp. 877-889
-
-
Serra, P.1
-
57
-
-
0034077559
-
CD4+CD25+ regulatory T cells down-regulate costimulatory molecules on antigen-presenting cells
-
Cederbom, L., Hall, H., and Ivars, F. 2000. CD4+CD25+ regulatory T cells down-regulate costimulatory molecules on antigen-presenting cells. Eur. J. Immunol. 30:1538-1543.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1538-1543
-
-
Cederbom, L.1
Hall, H.2
Ivars, F.3
-
58
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
Takahashi, T., et al. 1998. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10:1969-1980.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
-
59
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton, A.M., and Shevach, E.M. 1998. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:287-296.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
60
-
-
0142242113
-
CD4+CD25+ T cells lyse antigen-presenting B cells by Fas-Fas ligand interaction in an epitope-specific manner
-
Janssens, W., Carlier, V., Wu, B., VanderElst, L., Jacquemin, M.G., and Saint-Remy, J.M. 2003. CD4+CD25+ T cells lyse antigen-presenting B cells by Fas-Fas ligand interaction in an epitope-specific manner. J. Immunol. 171:4604-4612.
-
(2003)
J. Immunol.
, vol.171
, pp. 4604-4612
-
-
Janssens, W.1
Carlier, V.2
Wu, B.3
VanderElst, L.4
Jacquemin, M.G.5
Saint-Remy, J.M.6
-
61
-
-
2442637772
-
Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function
-
Thornton, A.M., Donovan, E.E., Piccirillo, C.A., and Shevach, E.M. 2004. Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function. J. Immunol. 172:6519-6523.
-
(2004)
J. Immunol.
, vol.172
, pp. 6519-6523
-
-
Thornton, A.M.1
Donovan, E.E.2
Piccirillo, C.A.3
Shevach, E.M.4
-
62
-
-
1642390941
-
Activation requirements for the induction of CD4+CD25+ T cell suppressor function
-
Thornton, A.M., Piccirillo, C.A., and Shevach, E.M. 2004. Activation requirements for the induction of CD4+CD25+ T cell suppressor function. Eur. J. Immunol. 34:366-376.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 366-376
-
-
Thornton, A.M.1
Piccirillo, C.A.2
Shevach, E.M.3
-
63
-
-
0042512461
-
Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells
-
Yamazaki, S., et al. 2003. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198:235-247.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 235-247
-
-
Yamazaki, S.1
-
64
-
-
0037436119
-
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
-
Pasare, C., and Medzhitov, R. 2003. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science. 299:1033-1036.
-
(2003)
Science
, vol.299
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
65
-
-
0036144888
-
Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo
-
Gavin, M.A., Clarke, S.R., Negrou, E., Gallegos, A., and Rudensky, A. 2002. Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo. Nat. Immunol. 3:33-41.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 33-41
-
-
Gavin, M.A.1
Clarke, S.R.2
Negrou, E.3
Gallegos, A.4
Rudensky, A.5
-
66
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
Asseman, C., Mauze, S., Leach, M.W., Coffman, R.L., and Powrie, F. 1999. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190:995-1004.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 995-1004
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
67
-
-
0034967640
-
Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells
-
Suri-Payer, E., and Cantor, H. 2001. Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J. Autoimmun. 16:115-123.
-
(2001)
J. Autoimmun.
, vol.16
, pp. 115-123
-
-
Suri-Payer, E.1
Cantor, H.2
-
68
-
-
0029813545
-
Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses
-
Berg, D.J., et al. 1996. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J. Clin. Invest. 98:1010-1020.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1010-1020
-
-
Berg, D.J.1
-
69
-
-
0029956024
-
A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells
-
Powrie, F., Carlino, J., Leach, M.W., Mauze, S., and Coffman, R.L. 1996. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J. Exp. Med. 183:2669-2674.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2669-2674
-
-
Powrie, F.1
Carlino, J.2
Leach, M.W.3
Mauze, S.4
Coffman, R.L.5
-
70
-
-
0035801335
-
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
Nakamura, K., Kitani, A., and Strober, W. 2001. Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J. Exp. Med. 194:629-644.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
71
-
-
0037371301
-
CD4+CD25- T cells that express latency-associated peptide on the surface suppress CD4+CD45RBhigh-induced colitis by a TGF-beta-dependent mechanism
-
Oida, T., et al. 2003. CD4+CD25- T cells that express latency-associated peptide on the surface suppress CD4+CD45RBhigh-induced colitis by a TGF-beta-dependent mechanism. J. Immunol. 170:2516-2522.
-
(2003)
J. Immunol.
, vol.170
, pp. 2516-2522
-
-
Oida, T.1
-
72
-
-
0037099613
-
CD4(+)CD25(+) regulatory T cells can mediate suppressor function in ehe absence of transforming growth factor beta1 production and responsiveness
-
Piccirillo, C.A., et al. 2002. CD4(+)CD25(+) regulatory T cells can mediate suppressor function in ehe absence of transforming growth factor beta1 production and responsiveness. J. Exp. Med. 196:237-246.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 237-246
-
-
Piccirillo, C.A.1
-
73
-
-
0035887739
-
Activation of CD25(+)CD4(+) regulatory T cells by oral antigen administration
-
Zhang, X., Izikson, L., Liu, L., and Weiner, H.L. 2001. Activation of CD25(+)CD4(+) regulatory T cells by oral antigen administration. J. Immunol. 167:4245-4253.
-
(2001)
J. Immunol.
, vol.167
, pp. 4245-4253
-
-
Zhang, X.1
Izikson, L.2
Liu, L.3
Weiner, H.L.4
-
74
-
-
4644369302
-
Interleukin-2 is essential for CD4(+)CD25(+) regulatory T cell function
-
De La Rosa, M., Rutz, S., Dorninger, H., and Scheffold, A. 2004. Interleukin-2 is essential for CD4(+)CD25(+) regulatory T cell function. Eur. J. Immunol. 34:2480-2488.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 2480-2488
-
-
De La Rosa, M.1
Rutz, S.2
Dorninger, H.3
Scheffold, A.4
-
75
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
Grohmann, U., et al. 2002. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat. Immunol. 3:1097-1101.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
-
76
-
-
0346119234
-
Modulation of tryptophan catabolism by regulatory T cells
-
Fallarino, F., et al. 2003. Modulation of tryptophan catabolism by regulatory T cells. Nat. Immunol. 4:1206-1212.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1206-1212
-
-
Fallarino, F.1
-
77
-
-
1642396607
-
Ligation of B7-1/B7-2 by human CD4(+) T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells
-
Munn, D.H., Sharma, M.D., and Mellor, A.L 2004. Ligation of B7-1/B7-2 by human CD4(+) T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. J. Immunol. 172:4100-4110.
-
(2004)
J. Immunol.
, vol.172
, pp. 4100-4110
-
-
Munn, D.H.1
Sharma, M.D.2
Mellor, A.L.3
-
78
-
-
0036669785
-
The interaction properties of costimulatory molecules revisited
-
Collins, A.V., et al. 2002. The interaction properties of costimulatory molecules revisited. Immunity. 17:201-210.
-
(2002)
Immunity
, vol.17
, pp. 201-210
-
-
Collins, A.V.1
-
79
-
-
0035421654
-
Cutting edge: Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
-
Piccirillo, C.A., and Shevach, E.M. 2001. Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J. Immunol. 167:1137-1140.
-
(2001)
J. Immunol.
, vol.167
, pp. 1137-1140
-
-
Piccirillo, C.A.1
Shevach, E.M.2
-
80
-
-
3142708571
-
Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
-
Paust, S., Lu, L., McCarty, N., and Cantor, H. 2004. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc. Natl. Acad. Sci. U. S. A. 101:10398-10403.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 10398-10403
-
-
Paust, S.1
Lu, L.2
McCarty, N.3
Cantor, H.4
-
81
-
-
0031092641
-
B7.2 expressed by T cells does not induce CD28-mediated costimulatory activity but retains CTLA4 binding: Implications for induction of antitumor immunity to T cell tumors
-
Greenfield, E.A., et al. 1997. B7.2 expressed by T cells does not induce CD28-mediated costimulatory activity but retains CTLA4 binding: implications for induction of antitumor immunity to T cell tumors. J. Immunol. 158:2025-2034.
-
(1997)
J. Immunol.
, vol.158
, pp. 2025-2034
-
-
Greenfield, E.A.1
-
82
-
-
0028963227
-
Reciprocal expression of co-stimulatory molecules, B7-1 and B7-2, on murine T cells following activation
-
Prabhu Das, M.R., et al. 1995. Reciprocal expression of co-stimulatory molecules, B7-1 and B7-2, on murine T cells following activation. Eur. J. Immunol. 25:207-211.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 207-211
-
-
Prabhu Das, M.R.1
-
83
-
-
0038068048
-
The CD4-related molecule, LAG-3 (CD223), regulates the expansion of activated T cells
-
Workman, C.J., and Vignali, D.A. 2003. The CD4-related molecule, LAG-3 (CD223), regulates the expansion of activated T cells. Eur. J. Immunol. 33:970-979.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 970-979
-
-
Workman, C.J.1
Vignali, D.A.2
-
84
-
-
5644263642
-
Role of LAG-3 in regulatory T cells
-
In press
-
Huang, C.-T., et al. Role of LAG-3 in regulatory T cells. Immunity. In press.
-
Immunity
-
-
Huang, C.-T.1
-
85
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou, I., and Von Boehmer, H. 2004. In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 199:1401-1408.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
Von Boehmer, H.2
-
86
-
-
0002384347
-
Induction of immunological paralysis in two zones of dosage
-
Mitchison, N.A. 1964. Induction of immunological paralysis in two zones of dosage. Proc. R. Soc. Lond. B Biol. Sci. 161:275-292.
-
(1964)
Proc. R. Soc. Lond. B Biol. Sci.
, vol.161
, pp. 275-292
-
-
Mitchison, N.A.1
-
87
-
-
0036372440
-
Transforming growth factor-beta in T-Cell biology
-
Gorelik, L., and Flavell, R.A. 2002. Transforming growth factor-beta in T-Cell biology. Nat. Rev. Immunol. 2:46-53.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 46-53
-
-
Gorelik, L.1
Flavell, R.A.2
-
88
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen, W., et al. 2003. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 198:1875-1886.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
-
89
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen-specific T-Cell responses and prevents colitis
-
Groux, H., et al. 1997. A CD4+ T-cell subset inhibits antigen-specific T-Cell responses and prevents colitis. Nature. 389:737-742.
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
-
90
-
-
0028037782
-
Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
-
Chen, Y., Kuchroo, V.K., Inobe, J., Hafler, D.A., and Weiner, H.L. 1994. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science. 265:1237-1240.
-
(1994)
Science
, vol.265
, pp. 1237-1240
-
-
Chen, Y.1
Kuchroo, V.K.2
Inobe, J.3
Hafler, D.A.4
Weiner, H.L.5
-
91
-
-
0038631849
-
Type 1 T-regulatory cells: Their role in the control of immune responses
-
Groux, H. 2003. Type 1 T-regulatory cells: their role in the control of immune responses. Transplantation. 75(Suppl. 9):8S-12S.
-
(2003)
Transplantation
, vol.75
, Issue.SUPPL. 9
-
-
Groux, H.1
-
92
-
-
0037018104
-
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
-
Barrat, F.J., et al. 2002. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J. Exp. Med. 195:603-616.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 603-616
-
-
Barrat, F.J.1
-
93
-
-
2442450433
-
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells
-
Vieira, P.L., et al. 2004. IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J. Immunol. 172:5986-5993.
-
(2004)
J. Immunol.
, vol.172
, pp. 5986-5993
-
-
Vieira, P.L.1
-
94
-
-
0035881234
-
Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance
-
Gregori, S., et al. 2001. Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J. Immunol. 167:1945-1953.
-
(2001)
J. Immunol.
, vol.167
, pp. 1945-1953
-
-
Gregori, S.1
-
95
-
-
0347895101
-
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
-
Kemper, C., et al. 2003. Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature. 421:388-392.
-
(2003)
Nature
, vol.421
, pp. 388-392
-
-
Kemper, C.1
-
96
-
-
0037339812
-
Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse
-
Sato, K., Yamashita, N., Baba, M., and Matsuyama, T. 2003. Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse. Immunity. 18:367-379.
-
(2003)
Immunity
, vol.18
, pp. 367-379
-
-
Sato, K.1
Yamashita, N.2
Baba, M.3
Matsuyama, T.4
-
97
-
-
0012391130
-
Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells
-
Sato, K., Yamashita, N., Baba, M., and Matsuyama, T. 2003. Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood. 101:3581-3589.
-
(2003)
Blood
, vol.101
, pp. 3581-3589
-
-
Sato, K.1
Yamashita, N.2
Baba, M.3
Matsuyama, T.4
-
98
-
-
0034613767
-
Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
-
Jonuleit, H., Schmitt, E., Schuler, G., Knop, J., and Enk, A.H. 2000. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192:1213-1222.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1213-1222
-
-
Jonuleit, H.1
Schmitt, E.2
Schuler, G.3
Knop, J.4
Enk, A.H.5
-
99
-
-
0042971652
-
Tolerogenic dendritic cells
-
Steinman, R.M., Hawiger, D., and Nussenzweig, M.C. 2003. Tolerogenic dendritic cells. Annu. Rev. Immunol. 21:685-711.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 685-711
-
-
Steinman, R.M.1
Hawiger, D.2
Nussenzweig, M.C.3
-
100
-
-
0033571105
-
Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity
-
Shimizu, J., Yamazaki, S., and Sakaguchi, S. 1999. Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J. Immunol. 163:5211-5218.
-
(1999)
J. Immunol.
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
Yamazaki, S.2
Sakaguchi, S.3
-
101
-
-
0035903324
-
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
-
Sutmuller, R.P., etal. 2001. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J. Exp. Med. 194:823-832.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 823-832
-
-
Sutmuller, R.P.1
-
102
-
-
0141461418
-
CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
-
Edinger, M., et al. 2003. CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat. Med. 9:1144-1150.
-
(2003)
Nat. Med.
, vol.9
, pp. 1144-1150
-
-
Edinger, M.1
-
103
-
-
0346690399
-
+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
-
doi:10.1172/JCI200317702
-
+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. J. Clin. Invest. 112:1688-1696. doi:10.1172/JCI200317702.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1688-1696
-
-
Trenado, A.1
-
104
-
-
4344653864
-
Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells
-
Nishimura, E., Sakihama, T., Setoguchi, R., Tanaka, K., and Sakaguchi, S. 2004. Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells. Int. Immunol. 16:1189-1201.
-
(2004)
Int. Immunol.
, vol.16
, pp. 1189-1201
-
-
Nishimura, E.1
Sakihama, T.2
Setoguchi, R.3
Tanaka, K.4
Sakaguchi, S.5
-
105
-
-
0037025943
-
Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
-
Hoffmann, P., Ermann, J., Edinger, M., Fathman, C.G., and Strober, S. 2002. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J. Exp. Med. 196:389-399.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 389-399
-
-
Hoffmann, P.1
Ermann, J.2
Edinger, M.3
Fathman, C.G.4
Strober, S.5
-
106
-
-
3543097547
-
Suppressor T cells in human diseases
-
Baecher-Allan, C., and Hafler, D.A. 2004. Suppressor T cells in human diseases. J. Exp. Med. 200:273-276.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 273-276
-
-
Baecher-Allan, C.1
Hafler, D.A.2
-
107
-
-
1842732224
-
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
-
Viglietta, V., Baecher-Allan, C., Weiner, H.L., and Hafler, D.A. 2004. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J. Exp. Med. 199:971-979.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 971-979
-
-
Viglietta, V.1
Baecher-Allan, C.2
Weiner, H.L.3
Hafler, D.A.4
-
108
-
-
3042594506
-
Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy
-
Karlsson, M.R., Rugtveit, J., and Brandtzaeg, P. 2004. Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy. J. Exp. Med. 199:1679-1688.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1679-1688
-
-
Karlsson, M.R.1
Rugtveit, J.2
Brandtzaeg, P.3
-
109
-
-
3543140687
-
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy
-
Ehrenstein, M.R., et al. 2004. Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy. J. Exp. Med. 200:277-285.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 277-285
-
-
Ehrenstein, M.R.1
-
110
-
-
3543098686
-
CD25+CD4+ regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4+ and CD8+ HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status
-
Kinter, A.L., et al. 2004. CD25+CD4+ regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4+ and CD8+ HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J. Exp. Med. 200:331-343.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 331-343
-
-
Kinter, A.L.1
-
111
-
-
0037261145
-
Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis
-
Cao, D., et al. 2003. Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis. Eur. J. Immunol. 33:215-223.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 215-223
-
-
Cao, D.1
-
112
-
-
15244361536
-
CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease
-
Cao, D., van Vollenhoven, R., Klareskog, L., Trollmo, C., and Malmstrom, V. 2004. CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease. Arthritis Res. Ther. 6:R335-R346.
-
(2004)
Arthritis Res. Ther.
, vol.6
-
-
Cao, D.1
Van Vollenhoven, R.2
Klareskog, L.3
Trollmo, C.4
Malmstrom, V.5
|