메뉴 건너뛰기




Volumn 118, Issue 11, 2008, Pages 3619-3628

Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 55849142632     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI33185     Document Type: Article
Times cited : (234)

References (38)
  • 1
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi, S. 2004. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22:531-562.
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 2
    • 0037093217 scopus 로고    scopus 로고
    • The infusion of ex vivo activated and expanded CD4(+) CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality
    • Taylor, P.A., Lees, C.J., and Blazar, B.R. 2002. The infusion of ex vivo activated and expanded CD4(+) CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood. 99:3493-3499.
    • (2002) Blood , vol.99 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 3
    • 0037026001 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T Cells: New therapeutics for graft-versus-host disease
    • Cohen, J.L., Trenado, A., Vasey, D., Klatzmann, D., and Salomon, B.L. 2002. CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease. J. Exp. Med. 196:401-406.
    • (2002) J. Exp. Med , vol.196 , pp. 401-406
    • Cohen, J.L.1    Trenado, A.2    Vasey, D.3    Klatzmann, D.4    Salomon, B.L.5
  • 4
    • 33748297521 scopus 로고    scopus 로고
    • The role of CD4+CD25hi regulatory T cells in the physiopathogeny of graft-versus-host disease
    • Cohen, J.L., and Boyer, O. 2006. The role of CD4+CD25hi regulatory T cells in the physiopathogeny of graft-versus-host disease. Curr. Opin. Immunol. 18:580-585.
    • (2006) Curr. Opin. Immunol , vol.18 , pp. 580-585
    • Cohen, J.L.1    Boyer, O.2
  • 5
    • 0037124359 scopus 로고    scopus 로고
    • Identification of regulatory T cells in tolerated allografts
    • Graca, L., Cobbold, S.P., and Waldmann, H. 2002. Identification of regulatory T cells in tolerated allografts. J. Exp. Med. 195:1641-1646.
    • (2002) J. Exp. Med , vol.195 , pp. 1641-1646
    • Graca, L.1    Cobbold, S.P.2    Waldmann, H.3
  • 6
    • 0035869432 scopus 로고    scopus 로고
    • IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
    • Hara, M., et al. 2001. IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J. Immunol. 166:3789-3796.
    • (2001) J. Immunol , vol.166 , pp. 3789-3796
    • Hara, M.1
  • 8
    • 0034705008 scopus 로고    scopus 로고
    • Significant frequencies of T cells with indirect anti-donor specificity in heart graft recipients with chronic rejection
    • Hornick, P.I., et al. 2000. Significant frequencies of T cells with indirect anti-donor specificity in heart graft recipients with chronic rejection. Circulation. 101:2405-2410.
    • (2000) Circulation , vol.101 , pp. 2405-2410
    • Hornick, P.I.1
  • 9
    • 0035893012 scopus 로고    scopus 로고
    • Loss of direct and maintenance of indirect alloresponses in renal allograft recipients: Implications for the pathogenesis of chronic allograft nephropathy
    • Baker, R.J., et al. 2001. Loss of direct and maintenance of indirect alloresponses in renal allograft recipients: implications for the pathogenesis of chronic allograft nephropathy. J. Immunol. 167:7199-7206.
    • (2001) J. Immunol , vol.167 , pp. 7199-7206
    • Baker, R.J.1
  • 10
    • 0032400989 scopus 로고    scopus 로고
    • Linked suppression of skin graft rejection can operate through indirect recognition
    • Wise, M.P., Bemelman, F., Cobbold, S.P., and Waldmann, H. 1998. Linked suppression of skin graft rejection can operate through indirect recognition. J. Immunol. 161:5813-5816.
    • (1998) J. Immunol , vol.161 , pp. 5813-5816
    • Wise, M.P.1    Bemelman, F.2    Cobbold, S.P.3    Waldmann, H.4
  • 11
    • 34247880494 scopus 로고    scopus 로고
    • Influence of direct and indirect allorecognition pathways on CD4(+) CD25(+) regulatory T-cell function in transplantation
    • Sanchez-Fueyo, A., et al. 2007. Influence of direct and indirect allorecognition pathways on CD4(+) CD25(+) regulatory T-cell function in transplantation. Transpl. Int. 20:534-541.
    • (2007) Transpl. Int , vol.20 , pp. 534-541
    • Sanchez-Fueyo, A.1
  • 12
    • 0141678976 scopus 로고    scopus 로고
    • Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo
    • Jiang, S., Camara, N., Lombardi, G., and Lechler, R.I. 2003. Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo. Blood. 102:2180-2186.
    • (2003) Blood , vol.102 , pp. 2180-2186
    • Jiang, S.1    Camara, N.2    Lombardi, G.3    Lechler, R.I.4
  • 13
    • 33846214275 scopus 로고    scopus 로고
    • In vitro-expanded donor alloantigen-specific CD4+CD25+ regulatory T cells promote experimental transplantation tolerance
    • Golshayan, D., et al. 2007. In vitro-expanded donor alloantigen-specific CD4+CD25+ regulatory T cells promote experimental transplantation tolerance. Blood. 109:827-835.
    • (2007) Blood , vol.109 , pp. 827-835
    • Golshayan, D.1
  • 14
    • 33845202473 scopus 로고    scopus 로고
    • In-vitro generation and characterisation of murine CD4+CD25+ regulatory T cells with indirect allospecificity
    • Tsang, J., et al. 2006. In-vitro generation and characterisation of murine CD4+CD25+ regulatory T cells with indirect allospecificity. Int. Immunopharmacol. 6:1883-1888.
    • (2006) Int. Immunopharmacol , vol.6 , pp. 1883-1888
    • Tsang, J.1
  • 15
    • 33845933590 scopus 로고    scopus 로고
    • Generation and expansion of human CD4+ CD25+ regulatory T cells with indirect allospecificity: Potential reagents to promote donor-specific transplantation tolerance
    • Jiang, S., et al. 2006. Generation and expansion of human CD4+ CD25+ regulatory T cells with indirect allospecificity: Potential reagents to promote donor-specific transplantation tolerance. Transplantation. 82:1738-1743.
    • (2006) Transplantation , vol.82 , pp. 1738-1743
    • Jiang, S.1
  • 16
    • 0034722722 scopus 로고    scopus 로고
    • Heterogeneity of T cell clones specific for a single indirect alloantigenic epitope (I-Ab/H-2Kd54-68) that mediate transplant rejection
    • Honjo, K., Xu, X.Y., and Bucy, R.P. 2000. Heterogeneity of T cell clones specific for a single indirect alloantigenic epitope (I-Ab/H-2Kd54-68) that mediate transplant rejection. Transplantation. 70:1516-1524.
    • (2000) Transplantation , vol.70 , pp. 1516-1524
    • Honjo, K.1    Xu, X.Y.2    Bucy, R.P.3
  • 17
    • 1142286327 scopus 로고    scopus 로고
    • CD4+ T-cell receptor transgenic T cells alone can reject vascularized heart transplants through the indirect pathway of alloantigen recognition
    • Honjo, K., Xu, X., and Bucy, R.P. 2004. CD4+ T-cell receptor transgenic T cells alone can reject vascularized heart transplants through the indirect pathway of alloantigen recognition. Transplantation. 77:452-455.
    • (2004) Transplantation , vol.77 , pp. 452-455
    • Honjo, K.1    Xu, X.2    Bucy, R.P.3
  • 18
    • 27144524938 scopus 로고    scopus 로고
    • Migration matters: Regulatory T-cell compartmentalization determines suppressive activity in vivo
    • Siegmund, K., et al. 2005. Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo. Blood. 106:3097-3104.
    • (2005) Blood , vol.106 , pp. 3097-3104
    • Siegmund, K.1
  • 19
    • 10744228165 scopus 로고    scopus 로고
    • Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance
    • Zheng, X.X., et al. 2003. Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance. Immunity. 19:503-514.
    • (2003) Immunity , vol.19 , pp. 503-514
    • Zheng, X.X.1
  • 20
    • 33846010510 scopus 로고    scopus 로고
    • Targeting acute allograft rejection by immunotherapy with ex vivo-expanded natural CD4+ CD25+ regulatory T cells
    • Xia, G., He, J., Zhang, Z., and Leventhal, J.R. 2006. Targeting acute allograft rejection by immunotherapy with ex vivo-expanded natural CD4+ CD25+ regulatory T cells. Transplantation. 82:1749-1755.
    • (2006) Transplantation , vol.82 , pp. 1749-1755
    • Xia, G.1    He, J.2    Zhang, Z.3    Leventhal, J.R.4
  • 21
    • 14844352743 scopus 로고    scopus 로고
    • CD25+CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: Antigen-specific reactivation in vivo is critical for bystander regulation
    • Karim, M., Feng, G., Wood, K.J., and Bushell, A.R. 2005. CD25+CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: antigen-specific reactivation in vivo is critical for bystander regulation. Blood. 105:4871-4877.
    • (2005) Blood , vol.105 , pp. 4871-4877
    • Karim, M.1    Feng, G.2    Wood, K.J.3    Bushell, A.R.4
  • 22
    • 38049020656 scopus 로고    scopus 로고
    • Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes
    • Joffre, O., et al. 2008. Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes. Nat. Med. 14:88-92.
    • (2008) Nat. Med , vol.14 , pp. 88-92
    • Joffre, O.1
  • 23
    • 32844466881 scopus 로고    scopus 로고
    • Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells
    • Nikolaeva, N., Bemelman, F.J., Yong, S.L., van Lier, R.A., and ten Berge, I.J. 2006. Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells. Transplantation. 81:445-454.
    • (2006) Transplantation , vol.81 , pp. 445-454
    • Nikolaeva, N.1    Bemelman, F.J.2    Yong, S.L.3    van Lier, R.A.4    ten Berge, I.J.5
  • 24
    • 33845915103 scopus 로고    scopus 로고
    • Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin
    • Strauss, L., et al. 2007. Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin. J. Immunol. 178:320-329.
    • (2007) J. Immunol , vol.178 , pp. 320-329
    • Strauss, L.1
  • 25
    • 33745861719 scopus 로고    scopus 로고
    • Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T cells
    • Valmori, D., et al. 2006. Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T cells. J. Immunol. 177:944-949.
    • (2006) J. Immunol , vol.177 , pp. 944-949
    • Valmori, D.1
  • 26
    • 20444373376 scopus 로고    scopus 로고
    • Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
    • Battaglia, M., Stabilini, A., and Roncarolo, M.G. 2005. Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. Blood. 105:4743-4748.
    • (2005) Blood , vol.105 , pp. 4743-4748
    • Battaglia, M.1    Stabilini, A.2    Roncarolo, M.G.3
  • 27
    • 4444231191 scopus 로고    scopus 로고
    • New spectrum of allorecognition pathways: Implications for graft rejection and transplantation tolerance
    • Jiang, S., Herrera, O., and Lechler, R.I. 2004. New spectrum of allorecognition pathways: implications for graft rejection and transplantation tolerance. Curr. Opin. Immunol. 16:550-557.
    • (2004) Curr. Opin. Immunol , vol.16 , pp. 550-557
    • Jiang, S.1    Herrera, O.2    Lechler, R.I.3
  • 28
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • Morgan, R.A., et al. 2006. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science. 314:126-129.
    • (2006) Science , vol.314 , pp. 126-129
    • Morgan, R.A.1
  • 29
    • 23844455192 scopus 로고    scopus 로고
    • Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice
    • Masteller, E.L., et al. 2005. Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice. J. Immunol. 175:3053-3059.
    • (2005) J. Immunol , vol.175 , pp. 3053-3059
    • Masteller, E.L.1
  • 30
    • 0037309288 scopus 로고    scopus 로고
    • Transfer of TCR genes into mature T cells is accompanied by the maintenance of parental T cell avidity
    • Rubinstein, M.P., et al. 2003. Transfer of TCR genes into mature T cells is accompanied by the maintenance of parental T cell avidity. J. Immunol. 170:1209-1217.
    • (2003) J. Immunol , vol.170 , pp. 1209-1217
    • Rubinstein, M.P.1
  • 31
    • 0037442013 scopus 로고    scopus 로고
    • Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes
    • Schaft, N., et al. 2003. Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes. J. Immunol. 170:2186-2194.
    • (2003) J. Immunol , vol.170 , pp. 2186-2194
    • Schaft, N.1
  • 32
    • 33746809277 scopus 로고    scopus 로고
    • High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT
    • Rezvani, K., et al. 2006. High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT. Blood. 108:1291-1297.
    • (2006) Blood , vol.108 , pp. 1291-1297
    • Rezvani, K.1
  • 33
    • 13544258633 scopus 로고    scopus 로고
    • Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation
    • Hanash, A.M., and Levy, R.B. 2005. Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation. Blood. 105:1828-1836.
    • (2005) Blood , vol.105 , pp. 1828-1836
    • Hanash, A.M.1    Levy, R.B.2
  • 34
    • 0034679567 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
    • Read, S., Malmstrom, V., and Powrie, F. 2000. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J. Exp. Med. 192:295-302.
    • (2000) J. Exp. Med , vol.192 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 36
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
    • Inaba, K., et al. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176:1693-1702.
    • (1992) J. Exp. Med , vol.176 , pp. 1693-1702
    • Inaba, K.1
  • 37
    • 0033849524 scopus 로고    scopus 로고
    • Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR
    • Willemsen, R.A., et al. 2000. Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR. Gene Ther. 7:1369-1377.
    • (2000) Gene Ther , vol.7 , pp. 1369-1377
    • Willemsen, R.A.1
  • 38
    • 0034810907 scopus 로고    scopus 로고
    • The technique for heterotopic cardiac transplantation in mice: Experience of 3000 operations by one surgeon
    • Niimi, M. 2001. The technique for heterotopic cardiac transplantation in mice: experience of 3000 operations by one surgeon. J. Heart Lung Transplant. 20:1123-1128.
    • (2001) J. Heart Lung Transplant , vol.20 , pp. 1123-1128
    • Niimi, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.