IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iT reg cell balance

Nature Immunology

Volumn 16, Issue 3, 2015, Pages 286-295

  Basu, Rajatava ^a   Whitley, Sarah K ^a   Bhaumik, Suniti ^a   Zindl, Carlene L ^a   Schoeb, Trenton R ^b   Benveniste, Etty N ^c   Pear, Warren S ^d   Hatton, Robin D ^a   Weaver, Casey T ^a  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; RETINOIC ACID; STAT PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR FOXP3; SOCS3 PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL INFECTION; CELL FATE; CELL MATURATION; CELL POLARITY; CITROBACTER RODENTIUM INFECTION; CONSENSUS SEQUENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ANTAGONISM; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; MEDIATOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TH17 CELL; TRANSCRIPTION INITIATION; ANIMAL; C57BL MOUSE; CD4+ T LYMPHOCYTE; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; HUMANS; INTERLEUKIN-1; MICE; MICE, INBRED C57BL; NF-KAPPA B; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; TRETINOIN;

EID: 84923437687     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3099     Document Type: Article

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