All-Trans retinoic acid promotes TGF-β-induced tregs via histone modification but not DNA demethylation on Foxp3 gene locus

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Lu, Ling ^a,c   Ma, Jilin ^d   Li, Zhiyuan ^h   Lan, Qin ^a,e   Chen, Maogen ^a   Liu, Ya ^a   Xia, Zanxian ^a   Wang, Julie ^a   Han, Yuanping ^b   Shi, Wei ^a   Quesniaux, Valerie ^f   Ryffel, Bernhard ^f   Brand, David ^g   Li, Bin ^h   Liu, Zhongmin ^e   Zheng, Song Guo ^a,f  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Key Laboratory of Living Donor Liver Transplantation   (China)

^d Zhejiang Traditional Chinese Medicine and Western Medicine Hospital   (China)

^e TONGJI UNIVERSITY   (China)

^f UNIVERSITÉ D'ORLÉANS   (France)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

^h INSTITUTE PASTEUR OF SHANGHAI   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; DNA; HISTONE; INTERLEUKIN 2 RECEPTOR ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCLONAL ANTIBODY; RETINOIC ACID; RNA POLYMERASE II; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CHRONIC GRAFT VERSUS HOST DISEASE; CLONAL ANERGY; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; DNA SEQUENCE; ENZYME ACTIVATION; GENE LOCUS; GENETIC CONSERVATION; HISTONE ACETYLATION; HISTONE METHYLATION; HISTONE MODIFICATION; INHIBITION KINETICS; KNOCKOUT MOUSE; LUPUS LIKE SYNDROME; LYMPHOCYTE DIFFERENTIATION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; SURVIVAL RATE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; FEMALE; GENETICS; MALE; METABOLISM; PHOSPHORYLATION;

ATRA; MUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; DNA; DNA METHYLATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HISTONES; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MALE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA; TRETINOIN;

EID: 80052744481     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024590     Document Type: Article

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