Methylation matters: Binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells

Journal of Molecular Medicine

Volumn 88, Issue 10, 2010, Pages 1029-1040

  Polansky, Julia K ^a,b   Schreiber, Lisa ^a   Thelemann, Christoph ^c   Ludwig, Leif ^c   Krüger, Melanie ^c   Baumgrass, Ria ^c   Cording, Sascha ^a   Floess, Stefan ^a   Hamann, Alf ^c   Huehn, Jochen ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b RESEARCH CENTER BORSTEL   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

DNA methylation; Epigenetic control; Gene expression; Transcription factors

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ARTICLE; BINDING SITE; CD4+ T LYMPHOCYTE; CELL LINEAGE; CELL MATURATION; CONTROLLED STUDY; CPG ISLAND; DEMETHYLATION; EPIGENETICS; GENETIC TRANSCRIPTION; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; METHYLATION; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; CPG ISLANDS; ENHANCER ELEMENTS, GENETIC; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; METHYLATION; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PROTO-ONCOGENE PROTEIN C-ETS-1; T-LYMPHOCYTES, REGULATORY;

EID: 78149408519     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-010-0642-1     Document Type: Article

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