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Volumn 105, Issue 4, 2005, Pages 1828-1836

Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN;

EID: 13544258633     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-08-3213     Document Type: Article
Times cited : (150)

References (62)
  • 2
    • 0021984561 scopus 로고
    • Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts
    • Martin PJ, Hansen JA, Buckner CD, et al. Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts. Blood. 1985;66:664-672.
    • (1985) Blood , vol.66 , pp. 664-672
    • Martin, P.J.1    Hansen, J.A.2    Buckner, C.D.3
  • 3
    • 0022620989 scopus 로고
    • Treatment of donor bone marrow with monoclonal anti-T-cell antibody and complement for the prevention of graft-versus-host disease: A prospective, randomized, double-blind trial
    • Mitsuyasu RT, Champlin RE, Gale RP, et al. Treatment of donor bone marrow with monoclonal anti-T-cell antibody and complement for the prevention of graft-versus-host disease: a prospective, randomized, double-blind trial. Ann Intern Med. 1986;105:20-26.
    • (1986) Ann Intern Med , vol.105 , pp. 20-26
    • Mitsuyasu, R.T.1    Champlin, R.E.2    Gale, R.P.3
  • 4
    • 0027294049 scopus 로고
    • Donor CD8 cells prevent allogeneic marrow graft rejection in mice: Potential implications for marrow transplantation in humans
    • Martin PJ. Donor CD8 cells prevent allogeneic marrow graft rejection in mice: potential implications for marrow transplantation in humans. J Exp Med. 1993;178:703-712.
    • (1993) J Exp Med , vol.178 , pp. 703-712
    • Martin, P.J.1
  • 5
    • 6444245092 scopus 로고    scopus 로고
    • The contribution of cytotoxic and noncytotoxic function by donor T-cells that support engraftment after allogeneic bone marrow transplantation
    • Jiang Z, Adams GB, Hanash AM, Scadden DT, Levy RB. The contribution of cytotoxic and noncytotoxic function by donor T-cells that support engraftment after allogeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2002;8:588-596.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 588-596
    • Jiang, Z.1    Adams, G.B.2    Hanash, A.M.3    Scadden, D.T.4    Levy, R.B.5
  • 6
    • 0029953810 scopus 로고    scopus 로고
    • The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice
    • Baker MB, Altman NH, Podack ER, Levy RB. The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice. J Exp Med. 1996;183:2645-2656.
    • (1996) J Exp Med , vol.183 , pp. 2645-2656
    • Baker, M.B.1    Altman, N.H.2    Podack, E.R.3    Levy, R.B.4
  • 7
    • 0032530890 scopus 로고    scopus 로고
    • Involvement of donor T-cell cytotoxic effector mechanisms in preventing allogeneic marrow graft rejection
    • Martin PJ, Akatsuka Y, Hahne M, Sale G. Involvement of donor T-cell cytotoxic effector mechanisms in preventing allogeneic marrow graft rejection. Blood. 1998;92:2177-2181.
    • (1998) Blood , vol.92 , pp. 2177-2181
    • Martin, P.J.1    Akatsuka, Y.2    Hahne, M.3    Sale, G.4
  • 8
    • 0035353187 scopus 로고    scopus 로고
    • Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect
    • Schmaltz C, Alpdogan O, Horndasch KJ, et al. Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect. Blood. 2001;97:2886-2895.
    • (2001) Blood , vol.97 , pp. 2886-2895
    • Schmaltz, C.1    Alpdogan, O.2    Horndasch, K.J.3
  • 9
    • 1642529828 scopus 로고    scopus 로고
    • Donor T cells lacking Fas ligand, and perforin retain the capacity to induce severe GvHD in minor histocompatibility antigen mismatched bone-marrow transplantation recipients
    • Marks L, Altman NH, Podack ER, Levy RB. Donor T cells lacking Fas ligand, and perforin retain the capacity to induce severe GvHD in minor histocompatibility antigen mismatched bone-marrow transplantation recipients. Transplantation. 2004;77:804-812.
    • (2004) Transplantation , vol.77 , pp. 804-812
    • Marks, L.1    Altman, N.H.2    Podack, E.R.3    Levy, R.B.4
  • 10
    • 0031821875 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • Thomton AM, Shevach EM. CD4(+)CD25(+) immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med. 1998;188:287-296.
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thomton, A.M.1    Shevach, E.M.2
  • 11
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25): Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol. 1995;155:1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 12
    • 0035806276 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
    • Taylor PA, Noelle RJ, Blazar BR. CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade. J Exp Med. 2001;193:1311-1317.
    • (2001) J Exp Med , vol.193 , pp. 1311-1317
    • Taylor, P.A.1    Noelle, R.J.2    Blazar, B.R.3
  • 13
    • 0037093217 scopus 로고    scopus 로고
    • The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality
    • Taylor PA, Lees CJ, Blazar BR. The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood. 2002;99:3493-3499.
    • (2002) Blood , vol.99 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 14
    • 0037025943 scopus 로고    scopus 로고
    • Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • Hoffmann P, Ermann J, Edinger M, Fathman CG, Strober S. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med. 2002;196:389-399.
    • (2002) J Exp Med , vol.196 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathman, C.G.4    Strober, S.5
  • 15
    • 0036435911 scopus 로고    scopus 로고
    • CD25(+) immunoregulatory T-cells of donor origin suppress alloreactivity after BMT
    • Johnson BD, Konkol MC, Truitt RL. CD25(+) immunoregulatory T-cells of donor origin suppress alloreactivity after BMT. Biol Blood Marrow Transplant. 2002;8:525-535.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 525-535
    • Johnson, B.D.1    Konkol, M.C.2    Truitt, R.L.3
  • 16
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi T, Kuniyasu Y, Toda M, et al. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol. 1998;10:1969-1980.
    • (1998) Int Immunol , vol.10 , pp. 1969-1980
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3
  • 17
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4(+)CD25(+) immunoregulatory T cells is antigen nonspecific
    • Thornton AM, Shevach EM. Suppressor effector function of CD4(+)CD25(+) immunoregulatory T cells is antigen nonspecific. J Immunol. 2000;164:183-190.
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 18
    • 0037083523 scopus 로고    scopus 로고
    • Preferential recognition of self antigens despite normal thymic deletion of CD4(+)CD25(+) regulatory T cells
    • Romagnoli P, Hudrisier D, van Meerwijk JPM. Preferential recognition of self antigens despite normal thymic deletion of CD4(+)CD25(+) regulatory T cells. J Immunol. 2002;168:1644-1648.
    • (2002) J Immunol , vol.168 , pp. 1644-1648
    • Romagnoli, P.1    Hudrisier, D.2    Van Meerwijk, J.P.M.3
  • 19
    • 2442494076 scopus 로고    scopus 로고
    • Human CD4+CD25+ regulatory T cells share equally complex and comparable repertoires with CD4+
    • Kasow KA, Chen X, Knowles J, et al. Human CD4+CD25+ regulatory T cells share equally complex and comparable repertoires with CD4+. J Immunol. 2004;172:6123-6128.
    • (2004) J Immunol , vol.172 , pp. 6123-6128
    • Kasow, K.A.1    Chen, X.2    Knowles, J.3
  • 20
    • 0038044861 scopus 로고    scopus 로고
    • IL-10 and TGF-beta induce alloreactive CD4+
    • Chen ZM, O'Shaughnessy MJ, Gramaglia I, et al. IL-10 and TGF-beta induce alloreactive CD4+. Blood. 2003;101:5076-5083.
    • (2003) Blood , vol.101 , pp. 5076-5083
    • Chen, Z.M.1    O'Shaughnessy, M.J.2    Gramaglia, I.3
  • 21
    • 0141678976 scopus 로고    scopus 로고
    • Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo
    • Jiang S, Camara N, Lombardi G, Lechler RI. Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo. Blood. 2003;102:2180-2186.
    • (2003) Blood , vol.102 , pp. 2180-2186
    • Jiang, S.1    Camara, N.2    Lombardi, G.3    Lechler, R.I.4
  • 22
    • 0346690399 scopus 로고    scopus 로고
    • Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
    • Trenado A, Charlotte F, Fisson S, et al. Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. J Clin Invest. 2003;112:1688-1696.
    • (2003) J Clin Invest , vol.112 , pp. 1688-1696
    • Trenado, A.1    Charlotte, F.2    Fisson, S.3
  • 23
    • 0033136719 scopus 로고    scopus 로고
    • Self-renewal, differentiation or death: Regulation and manipulation of hematopoietic stem cell fate
    • Domen J, Weissman IL. Self-renewal, differentiation or death: regulation and manipulation of hematopoietic stem cell fate. Mol Med Today. 1999;5:201-208.
    • (1999) Mol Med Today , vol.5 , pp. 201-208
    • Domen, J.1    Weissman, I.L.2
  • 24
    • 0033230515 scopus 로고    scopus 로고
    • CD8+TCR+ and CD8+TCR- cells in whole bone marrow facilitate the engraftment of hematopoietic stem cells across allogeneic barriers
    • Gandy KL, Domen J, Aguila H, Weissman IL. CD8+TCR+ and CD8+TCR- cells in whole bone marrow facilitate the engraftment of hematopoietic stem cells across allogeneic barriers. Immunity. 1999;11:579-590.
    • (1999) Immunity , vol.11 , pp. 579-590
    • Gandy, K.L.1    Domen, J.2    Aguila, H.3    Weissman, I.L.4
  • 25
    • 0035320679 scopus 로고    scopus 로고
    • Thymic selection of CD4(+)CD25(+) regulatory T cells induced by an agonist self-peptide
    • Jordan MS, Boesteanu A, Reed AJ, et al. Thymic selection of CD4(+)CD25(+) regulatory T cells induced by an agonist self-peptide. Nat Immunol. 2001;2:301-306.
    • (2001) Nat Immunol , vol.2 , pp. 301-306
    • Jordan, M.S.1    Boesteanu, A.2    Reed, A.J.3
  • 26
    • 0036345337 scopus 로고    scopus 로고
    • Origin of regulatory T cells with known specificity for antigen
    • Apostolou I, Sarukhan A, Klein L, von Boehmer H. Origin of regulatory T cells with known specificity for antigen. Nat Immunol. 2002;3:756-763.
    • (2002) Nat Immunol , vol.3 , pp. 756-763
    • Apostolou, I.1    Sarukhan, A.2    Klein, L.3    Von Boehmer, H.4
  • 27
    • 0041884743 scopus 로고    scopus 로고
    • Continuous activation of autoreactive CD4(+) CD25(+) regulatory T cells in the steady state
    • Fisson S, Darrasse-Jeze G, Litvinova E, et al. Continuous activation of autoreactive CD4(+) CD25(+) regulatory T cells in the steady state. J Exp Med. 2003;198:737-746.
    • (2003) J Exp Med , vol.198 , pp. 737-746
    • Fisson, S.1    Darrasse-Jeze, G.2    Litvinova, E.3
  • 28
    • 0035869432 scopus 로고    scopus 로고
    • IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
    • Hara M, Kingsley CI, Niimi M, et al. IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J Immunol. 2001;166:3789-3796.
    • (2001) J Immunol , vol.166 , pp. 3789-3796
    • Hara, M.1    Kingsley, C.I.2    Niimi, M.3
  • 30
    • 0344585521 scopus 로고    scopus 로고
    • Cutting edge: Self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cells
    • Cozzo C, Larkin J III, Caton AJ. Cutting edge: self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cells. J Immunol. 2003;171:5678-5682.
    • (2003) J Immunol , vol.171 , pp. 5678-5682
    • Cozzo, C.1    Larkin III, J.2    Caton, A.J.3
  • 31
    • 0023631856 scopus 로고
    • Acute rejection of murine bone marrow allogratts by natural Killer cells and T cells: Differences in kinetics and target antigens recognized
    • Murphy WJ, Kumar V, Bennett M. Acute rejection of murine bone marrow allogratts by natural Killer cells and T cells: differences in kinetics and target antigens recognized. J Exp Med. 1987;166:1499-1550.
    • (1987) J Exp Med , vol.166 , pp. 1499-1550
    • Murphy, W.J.1    Kumar, V.2    Bennett, M.3
  • 32
    • 0041589414 scopus 로고    scopus 로고
    • Human CD4+ CD25+ regulatory T cells suppress NKT cell functions
    • Azuma T, Takahashi T, Kunisato A, Kitamura T, Hirai H. Human CD4+ CD25+ regulatory T cells suppress NKT cell functions. Cancer Res. 2003;63:4516-4520.
    • (2003) Cancer Res , vol.63 , pp. 4516-4520
    • Azuma, T.1    Takahashi, T.2    Kunisato, A.3    Kitamura, T.4    Hirai, H.5
  • 33
    • 0037243827 scopus 로고    scopus 로고
    • CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
    • Maloy KJ, Salaun L, Cahill R, et al. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J Exp Med. 2003;197:111-119.
    • (2003) J Exp Med , vol.197 , pp. 111-119
    • Maloy, K.J.1    Salaun, L.2    Cahill, R.3
  • 34
    • 0035284804 scopus 로고    scopus 로고
    • CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10
    • Annacker O, Pimenta-Araujo R, Burlen-Defranoux O, et al. CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10. J Immunol. 2001;166:3008-3018.
    • (2001) J Immunol , vol.166 , pp. 3008-3018
    • Annacker, O.1    Pimenta-Araujo, R.2    Burlen-Defranoux, O.3
  • 35
    • 0036195161 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • McHugh RS, Whitters MJ, Piccirillo CA, et al. CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity. 2002;16:311-323.
    • (2002) Immunity , vol.16 , pp. 311-323
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillo, C.A.3
  • 36
    • 0030962532 scopus 로고    scopus 로고
    • Effect of interleukin-10 on dendritic cell maturation and function
    • DeSmedt T, VanMechelen M, DeBecker G, et al. Effect of interleukin-10 on dendritic cell maturation and function. Eur J Immunol. 1997;27:1229-1235.
    • (1997) Eur J Immunol , vol.27 , pp. 1229-1235
    • DeSmedt, T.1    VanMechelen, M.2    DeBecker, G.3
  • 37
    • 0742288835 scopus 로고    scopus 로고
    • The immunobiology of natural killer cells and bone marrow allograft rejection
    • Barao I, Murphy WJ. The immunobiology of natural killer cells and bone marrow allograft rejection. Biol Blood Marrow Transplant. 2003;9:727-741.
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 727-741
    • Barao, I.1    Murphy, W.J.2
  • 38
    • 0022587127 scopus 로고
    • Evidence for the in vivo production and release into the serum of a T-cell lymphokine, persisting-cell stimulating factor (PSF), during graft-versus-host reactions
    • Crapper RM, Schrader JW. Evidence for the in vivo production and release into the serum of a T-cell lymphokine, persisting-cell stimulating factor (PSF), during graft-versus-host reactions. Immunology. 1986;57:553-558.
    • (1986) Immunology , vol.57 , pp. 553-558
    • Crapper, R.M.1    Schrader, J.W.2
  • 39
    • 0025054653 scopus 로고
    • Frequency analysis of lymphokine-secreting CD4+ and CD8+ T cells activated in a graft-versus-host reaction
    • Kelso A. Frequency analysis of lymphokine-secreting CD4+ and CD8+ T cells activated in a graft-versus-host reaction. J Immunol. 1990;145:2167-2176.
    • (1990) J Immunol , vol.145 , pp. 2167-2176
    • Kelso, A.1
  • 40
    • 0025262234 scopus 로고
    • Alterations in T cell-derived colony-stimulating factors associated with GVH-induced immune deficiency
    • Hakim FT, Pluznik DH, Shearer GM. Alterations in T cell-derived colony-stimulating factors associated with GVH-induced immune deficiency. Transplantation. 1990;49:773-781.
    • (1990) Transplantation , vol.49 , pp. 773-781
    • Hakim, F.T.1    Pluznik, D.H.2    Shearer, G.M.3
  • 41
    • 0025264398 scopus 로고
    • Factors contributing to the decrease in concanavalin A-induced colony-stimulating factors in acute suppressive graft-versus-host disorder
    • Hakim FT, Pluznik DH, Shearer GM. Factors contributing to the decrease in concanavalin A-induced colony-stimulating factors in acute suppressive graft-versus-host disorder. Transplantation. 1990;49:781-787.
    • (1990) Transplantation , vol.49 , pp. 781-787
    • Hakim, F.T.1    Pluznik, D.H.2    Shearer, G.M.3
  • 42
    • 0035801335 scopus 로고    scopus 로고
    • Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • Nakamura K, Kitani A, Strober W. Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med. 2001;194:629-644.
    • (2001) J Exp Med , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 43
    • 1642287000 scopus 로고    scopus 로고
    • IL-3 affects endothelial cell-mediated smooth muscle cell recruitment by increasing TGF beta activity, potential role in tumor vessel stabilization
    • Dentelli P, Rosso A, Calvi C, et al. IL-3 affects endothelial cell-mediated smooth muscle cell recruitment by increasing TGF beta activity, potential role in tumor vessel stabilization. Oncogene. 2004;23:1681-1692.
    • (2004) Oncogene , vol.23 , pp. 1681-1692
    • Dentelli, P.1    Rosso, A.2    Calvi, C.3
  • 44
    • 0034665777 scopus 로고    scopus 로고
    • Transforming growth factor-beta: Pleiotropic role in the regulation of hematopoiesis
    • Fortunel NO, Hatzfeld A, Hatzfeld JA. Transforming growth factor-beta: pleiotropic role in the regulation of hematopoiesis. Blood. 2000;96:2022-2036.
    • (2000) Blood , vol.96 , pp. 2022-2036
    • Fortunel, N.O.1    Hatzfeld, A.2    Hatzfeld, J.A.3
  • 45
    • 0034283746 scopus 로고    scopus 로고
    • Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro
    • Bryder D, Jacobsen SEW. Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro. Blood. 2000;96:1748-1755.
    • (2000) Blood , vol.96 , pp. 1748-1755
    • Bryder, D.1    Jacobsen, S.E.W.2
  • 46
    • 0036789940 scopus 로고    scopus 로고
    • Transforming growth factor-beta(1) augments granulocyte-macrophage colony-stimulating factor-induced proliferation of umbilical cord blood CD34(+) cells with an associated tyrosine phosphorylation of STAT5
    • Suzuki M, Harashima A, Okochi A, et al. Transforming growth factor-beta(1) augments granulocyte-macrophage colony-stimulating factor-induced proliferation of umbilical cord blood CD34(+) cells with an associated tyrosine phosphorylation of STAT5. Exp Hematol. 2002;30:1132-1138.
    • (2002) Exp Hematol , vol.30 , pp. 1132-1138
    • Suzuki, M.1    Harashima, A.2    Okochi, A.3
  • 47
    • 0034851155 scopus 로고    scopus 로고
    • IL-10 increases the number of CFU-GM generated by ex vivo expansion of unmanipulated human MNCs and selected CD34+ cells
    • Wagner T, Fritsch G, Thalhammer R, et al. IL-10 increases the number of CFU-GM generated by ex vivo expansion of unmanipulated human MNCs and selected CD34+ cells. Transfusion. 2001;41:659-666.
    • (2001) Transfusion , vol.41 , pp. 659-666
    • Wagner, T.1    Fritsch, G.2    Thalhammer, R.3
  • 48
    • 19044385055 scopus 로고    scopus 로고
    • Ex vivo expansion of long-term culture initiating marrow cells by IL-10, SCF, and IL-3
    • Keil F, Elahi F, Greinix HT, et al. Ex vivo expansion of long-term culture initiating marrow cells by IL-10, SCF, and IL-3. Transfusion. 2002;42:581-587.
    • (2002) Transfusion , vol.42 , pp. 581-587
    • Keil, F.1    Elahi, F.2    Greinix, H.T.3
  • 49
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J, Niu C, Ye L, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature. 2003;425:836-841.
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3
  • 50
    • 0242268524 scopus 로고    scopus 로고
    • Osteoblastic cells regulate the haematopoietic stem cell niche
    • Calvi LM, Adams GB, Weibrecht KW, et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature. 2003;425:841-846.
    • (2003) Nature , vol.425 , pp. 841-846
    • Calvi, L.M.1    Adams, G.B.2    Weibrecht, K.W.3
  • 51
    • 0032530638 scopus 로고    scopus 로고
    • Constitutive up-regulation of integrin-mediated adhesion of tumor-infiltrating lymphocytes to osteoblasts and bone marrow-derived stromal cells
    • Tanaka Y, Mine S, Hanagiri T, et al. Constitutive up-regulation of integrin-mediated adhesion of tumor-infiltrating lymphocytes to osteoblasts and bone marrow-derived stromal cells. Cancer Res. 1998;58:4138-4145.
    • (1998) Cancer Res , vol.58 , pp. 4138-4145
    • Tanaka, Y.1    Mine, S.2    Hanagiri, T.3
  • 52
    • 1242294535 scopus 로고    scopus 로고
    • Recruitment and proliferation of T lymphocytes is supported by IFNgamma- and TNFalpha-activated human osteoblasts: Involvement of CD54 (ICAM-1) and CD106 (VCAM-1) adhesion molecules and CXCR3 chemokine receptor
    • Lisignoli G, Toneguzzi S, Piacentini A, et al. Recruitment and proliferation of T lymphocytes is supported by IFNgamma- and TNFalpha-activated human osteoblasts: involvement of CD54 (ICAM-1) and CD106 (VCAM-1) adhesion molecules and CXCR3 chemokine receptor. J Cell Physiol. 2004;198:388-398.
    • (2004) J Cell Physiol , vol.198 , pp. 388-398
    • Lisignoli, G.1    Toneguzzi, S.2    Piacentini, A.3
  • 53
    • 0035991663 scopus 로고    scopus 로고
    • Transplanted hematopoietic cells seed in clusters in recipient bone marrow in vivo
    • Askenasy N, Horina T, Farkas DL, Shalit I. Transplanted hematopoietic cells seed in clusters in recipient bone marrow in vivo. Stem Cells. 2002;20:301-310.
    • (2002) Stem Cells , vol.20 , pp. 301-310
    • Askenasy, N.1    Horina, T.2    Farkas, D.L.3    Shalit, I.4
  • 54
    • 0035885956 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF)-mediated activation of the p55 TNF receptor negatively regulates maintenance of cycling reconstituting human hematopoietic stem cells
    • Dybedal I, Bryder D, Fossum A, Rusten LS, Jacobsen SEW. Tumor necrosis factor (TNF)-mediated activation of the p55 TNF receptor negatively regulates maintenance of cycling reconstituting human hematopoietic stem cells. Blood. 2001;98:1782-1791.
    • (2001) Blood , vol.98 , pp. 1782-1791
    • Dybedal, I.1    Bryder, D.2    Fossum, A.3    Rusten, L.S.4    Jacobsen, S.E.W.5
  • 55
    • 0035477090 scopus 로고    scopus 로고
    • Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation
    • Bryder D, Ramsfjell V, Dybedal I, et al. Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation. J Exp Med. 2001;194:941-952.
    • (2001) J Exp Med , vol.194 , pp. 941-952
    • Bryder, D.1    Ramsfjell, V.2    Dybedal, I.3
  • 57
    • 2542496868 scopus 로고    scopus 로고
    • Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes
    • Joffre O, Gorsse N, Romagnoli P, van Meerwijk JP. Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes. Blood. 2004;103:4216-4221.
    • (2004) Blood , vol.103 , pp. 4216-4221
    • Joffre, O.1    Gorsse, N.2    Romagnoli, P.3    Van Meerwijk, J.P.4
  • 58
    • 9444280125 scopus 로고    scopus 로고
    • + T regulatory cells are potent inhibitors of GVHD and BM graft rejection
    • + T regulatory cells are potent inhibitors of GVHD and BM graft rejection. Blood. 2004;104:840-846.
    • (2004) Blood , vol.104 , pp. 840-846
    • Taylor, P.A.1    Panoskaltsis-Mortari, A.2    Swedin, J.M.3
  • 59
    • 0035874949 scopus 로고    scopus 로고
    • Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
    • Woo EY, Chu CS, Goletz TJ, et al. Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res. 2001;61:4766-4772.
    • (2001) Cancer Res , vol.61 , pp. 4766-4772
    • Woo, E.Y.1    Chu, C.S.2    Goletz, T.J.3
  • 60
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage UK, Moore TT, Joo HG, et al. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol. 2002;169:2756-2761.
    • (2002) J Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.G.3
  • 61
    • 0242557055 scopus 로고    scopus 로고
    • Post-hematopoietic cell transplantation control of graft-versus-host disease by donor CD425 T cells to allow an effective graft-versus-leukemia response
    • Jones SC, Murphy GF, Korngold R. Post-hematopoietic cell transplantation control of graft-versus-host disease by donor CD425 T cells to allow an effective graft-versus-leukemia response. Biol Blood Marrow Transplant. 2003;9:243-256.
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 243-256
    • Jones, S.C.1    Murphy, G.F.2    Korngold, R.3
  • 62
    • 0141461418 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
    • Edinger M, Hoffmann P, Ermann J, et al. CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat Med. 2003;9:1144-1150.
    • (2003) Nat Med , vol.9 , pp. 1144-1150
    • Edinger, M.1    Hoffmann, P.2    Ermann, J.3


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