Ex vivo expanded human regulatory T cells can prolong survival of a human islet allograft in a humanized mouse model

Transplantation

Volumn 96, Issue 8, 2013, Pages 707-716

  Wu, Douglas C ^a   Hester, Joanna ^a   Nadig, Satish N ^a   Zhang, Wei ^a   Trzonkowski, Piotr ^a,b   Gray, Derek ^a   Hughes, Stephen ^a   Johnson, Paul ^a   Wood, Kathryn J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Allograft; Cellular therapy; Humanized mouse model; Islet transplantation; Regulatory T cells

Indexed keywords

CD4 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; L SELECTIN; STAT PROTEIN; STREPTOZOCIN; TRANSCRIPTION FACTOR FOXP3;

ALLOIMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETES MELLITUS; EX VIVO STUDY; GRAFT REJECTION; GRAFT SURVIVAL; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IN VITRO STUDY; KIDNEY CAPSULE; LYMPHOCYTE PROLIFERATION; LYMPHOID TISSUE; MOUSE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; STREPTOZOCIN DIABETES;

ADOPTIVE TRANSFER; ANIMALS; CELL DIFFERENTIATION; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; INTERFERON-GAMMA; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TRANSPLANTATION, HETEROLOGOUS; TRANSPLANTATION, HOMOLOGOUS;

EID: 84886092766     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31829fa271     Document Type: Article

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