메뉴 건너뛰기




Volumn 43, Issue 8, 2013, Pages 2043-2054

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner

Author keywords

Conversion; Human; Regulatory T (Treg) cells; STAT3; Th17

Indexed keywords

CD161 ANTIGEN; CD45RA ANTIGEN; ETANERCEPT; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 7 RECEPTOR; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3;

EID: 84881527926     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201243296     Document Type: Article
Times cited : (111)

References (57)
  • 1
    • 33746356813 scopus 로고    scopus 로고
    • Human regulatory T cells and their role in autoimmune disease
    • Baecher-Allan, C. and Hafler, D. A., Human regulatory T cells and their role in autoimmune disease. Immunol. Rev. 2006. 212: 203-216.
    • (2006) Immunol. Rev. , vol.212 , pp. 203-216
    • Baecher-Allan, C.1    Hafler, D.A.2
  • 2
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 1998. 188: 287-296.
    • (1998) J. Exp. Med. , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 3
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • Brunkow, M. E., Jeffery, E. W., Hjerrild, K. A., Paeper, B., Clark, L. B., Yasayko, S. A., Wilkinson, J. E. et al., Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 2001. 27: 68-73.
    • (2001) Nat. Genet. , vol.27 , pp. 68-73
    • Brunkow, M.E.1    Jeffery, E.W.2    Hjerrild, K.A.3    Paeper, B.4    Clark, L.B.5    Yasayko, S.A.6    Wilkinson, J.E.7
  • 4
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • Bennett, C. L., Christie, J., Ramsdell, F., Brunkow, M. E., Ferguson, P. J., Whitesell, L., Kelly, T. E. et al., The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 2001. 27: 20-21.
    • (2001) Nat. Genet. , vol.27 , pp. 20-21
    • Bennett, C.L.1    Christie, J.2    Ramsdell, F.3    Brunkow, M.E.4    Ferguson, P.J.5    Whitesell, L.6    Kelly, T.E.7
  • 5
    • 3543140687 scopus 로고    scopus 로고
    • Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy
    • Ehrenstein, M. R., Evans, J. G., Singh, A., Moore, S., Warnes, G., Isenberg, D. A. and Mauri, C., Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy. J. Exp. Med. 2004. 200: 277-285.
    • (2004) J. Exp. Med. , vol.200 , pp. 277-285
    • Ehrenstein, M.R.1    Evans, J.G.2    Singh, A.3    Moore, S.4    Warnes, G.5    Isenberg, D.A.6    Mauri, C.7
  • 6
    • 12144249838 scopus 로고    scopus 로고
    • Defective suppressor function in CD4(+)CD25(+) T cells from patients with type 1 diabetes
    • Lindley, S., Dayan, C. M., Bishop, A., Roep, B. O., Peakman, M. and Tree, T. I., Defective suppressor function in CD4(+)CD25(+) T cells from patients with type 1 diabetes. Diabetes 2005. 54: 92-99.
    • (2005) Diabetes , vol.54 , pp. 92-99
    • Lindley, S.1    Dayan, C.M.2    Bishop, A.3    Roep, B.O.4    Peakman, M.5    Tree, T.I.6
  • 7
    • 33746373909 scopus 로고    scopus 로고
    • The regulation of allergy and asthma
    • Umetsu, D. T. and DeKruyff, R. H., The regulation of allergy and asthma. Immunol. Rev. 2006. 212: 238-255.
    • (2006) Immunol. Rev. , vol.212 , pp. 238-255
    • Umetsu, D.T.1    DeKruyff, R.H.2
  • 8
    • 33746369415 scopus 로고    scopus 로고
    • Regulatory T-cell physiology and application to treat autoimmunity
    • Tang, Q. and Bluestone, J. A., Regulatory T-cell physiology and application to treat autoimmunity. Immunol. Rev. 2006. 212: 217-237.
    • (2006) Immunol. Rev. , vol.212 , pp. 217-237
    • Tang, Q.1    Bluestone, J.A.2
  • 9
    • 0037124359 scopus 로고    scopus 로고
    • Identification of regulatory T cells in tolerated allografts
    • Graca, L., Cobbold, S. P. and Waldmann, H., Identification of regulatory T cells in tolerated allografts. J. Exp. Med. 2002. 195: 1641-1646.
    • (2002) J. Exp. Med. , vol.195 , pp. 1641-1646
    • Graca, L.1    Cobbold, S.P.2    Waldmann, H.3
  • 10
    • 58849121453 scopus 로고    scopus 로고
    • The presence of Foxp3 expressing T cells within grafts of tolerant human liver transplant recipients
    • Li, Y., Zhao, X., Cheng, D., Haga, H., Tsuruyama, T., Wood, K., Sakaguchi, S. et al., The presence of Foxp3 expressing T cells within grafts of tolerant human liver transplant recipients. Transplantation 2008. 86: 1837-1843.
    • (2008) Transplantation , vol.86 , pp. 1837-1843
    • Li, Y.1    Zhao, X.2    Cheng, D.3    Haga, H.4    Tsuruyama, T.5    Wood, K.6    Sakaguchi, S.7
  • 11
    • 76649106437 scopus 로고    scopus 로고
    • Regulatory T cells in kidney allograft infiltrates correlate with initial inflammation and graft function
    • Taflin, C., Nochy, D., Hill, G., Frouget, T., Rioux, N., Vérine, J., Bruneval, P. et al., Regulatory T cells in kidney allograft infiltrates correlate with initial inflammation and graft function. Transplantation 2010. 89: 194-199.
    • (2010) Transplantation , vol.89 , pp. 194-199
    • Taflin, C.1    Nochy, D.2    Hill, G.3    Frouget, T.4    Rioux, N.5    Vérine, J.6    Bruneval, P.7
  • 12
    • 33845379986 scopus 로고    scopus 로고
    • Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients
    • Battaglia, M., Stabilini, A., Migliavacca, B., Horejs-Hoeck, J., Kaupper, T. and Roncarolo, M. G., Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients. J. Immunol. 2006. 177: 8338-8347.
    • (2006) J. Immunol. , vol.177 , pp. 8338-8347
    • Battaglia, M.1    Stabilini, A.2    Migliavacca, B.3    Horejs-Hoeck, J.4    Kaupper, T.5    Roncarolo, M.G.6
  • 13
    • 84880968811 scopus 로고    scopus 로고
    • Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+FOXP3+ Treg subpopulations
    • Haematologica
    • Scotta, C., Esposito, M., Fazekasova, H., Fanelli, G., Edozie, F. C., Ali, N., Xiao, F. et al., Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+FOXP3+ Treg subpopulations. Haematologica 2013. 98: 1291-1299.
    • (2013) , vol.98 , pp. 1291-1299
    • Scotta, C.1    Esposito, M.2    Fazekasova, H.3    Fanelli, G.4    Edozie, F.C.5    Ali, N.6    Xiao, F.7
  • 14
    • 84856908569 scopus 로고    scopus 로고
    • CD4(+)Foxp3(+) regulatory T cell therapy in transplantation
    • Tang, Q., Bluestone, J. A. and Kang, S. M., CD4(+)Foxp3(+) regulatory T cell therapy in transplantation. J. Mol. Cell Biol. 2012. 4: 11-21.
    • (2012) J. Mol. Cell Biol. , vol.4 , pp. 11-21
    • Tang, Q.1    Bluestone, J.A.2    Kang, S.M.3
  • 16
    • 70249122695 scopus 로고    scopus 로고
    • First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells
    • Trzonkowski, P., Bieniaszewska, M., Juścińska, J., Dobyszuk, A., Krzystyniak, A., Marek, N., Myśliwska, J. et al., First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells. Clin. Immunol. 2009. 133: 22-26.
    • (2009) Clin. Immunol. , vol.133 , pp. 22-26
    • Trzonkowski, P.1    Bieniaszewska, M.2    Juścińska, J.3    Dobyszuk, A.4    Krzystyniak, A.5    Marek, N.6    Myśliwska, J.7
  • 17
    • 77649220954 scopus 로고    scopus 로고
    • Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells
    • O'shea, J. J. and Paul, W. E., Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells. Science 2010. 327: 1098-1102.
    • (2010) Science , vol.327 , pp. 1098-1102
    • O'shea, J.J.1    Paul, W.E.2
  • 18
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L. et al., Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006. 441: 235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7
  • 20
    • 33847667225 scopus 로고    scopus 로고
    • The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
    • Afzali, B., Lombardi, G., Lechler, R. I. and Lord, G. M., The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin. Exp. Immunol. 2007. 148: 32-46.
    • (2007) Clin. Exp. Immunol. , vol.148 , pp. 32-46
    • Afzali, B.1    Lombardi, G.2    Lechler, R.I.3    Lord, G.M.4
  • 21
    • 33748174156 scopus 로고    scopus 로고
    • T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype
    • Mathur, A. N., Chang, H.-C., Zisoulis, D. G., Kapur, R., Belladonna, M. L., Kansas, G. S. and Kaplan, M. H., T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. Blood 2006. 108: 1595-1601.
    • (2006) Blood , vol.108 , pp. 1595-1601
    • Mathur, A.N.1    Chang, H.-C.2    Zisoulis, D.G.3    Kapur, R.4    Belladonna, M.L.5    Kansas, G.S.6    Kaplan, M.H.7
  • 26
    • 55149094300 scopus 로고    scopus 로고
    • Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
    • Koenen, H. J. P. M., Smeets, R. L., Vink, P. M., Van Rijssen, E., Boots, A. M. H. and Joosten, I., Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 2008. 112: 2340-2352.
    • (2008) Blood , vol.112 , pp. 2340-2352
    • Koenen, H.J.P.M.1    Smeets, R.L.2    Vink, P.M.3    Van Rijssen, E.4    Boots, A.M.H.5    Joosten, I.6
  • 27
    • 72949119542 scopus 로고    scopus 로고
    • Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells
    • Afzali, B., Mitchell, P., Lechler, R. I., John, S. and Lombardi, G., Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells. Clin. Exp. Immunol. 2010. 159: 120-130.
    • (2010) Clin. Exp. Immunol. , vol.159 , pp. 120-130
    • Afzali, B.1    Mitchell, P.2    Lechler, R.I.3    John, S.4    Lombardi, G.5
  • 29
    • 79952300978 scopus 로고    scopus 로고
    • Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases
    • Hovhannisyan, Z., Treatman, J., Littman, D. R. and Mayer, L., Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology 2011. 140: 957-965.
    • (2011) Gastroenterology , vol.140 , pp. 957-965
    • Hovhannisyan, Z.1    Treatman, J.2    Littman, D.R.3    Mayer, L.4
  • 30
    • 79959782887 scopus 로고    scopus 로고
    • Regulatory T cell plasticity: beyond the controversies
    • Hori, S., Regulatory T cell plasticity: beyond the controversies. Trends Immunol. 2011. 32: 295-300.
    • (2011) Trends Immunol. , vol.32 , pp. 295-300
    • Hori, S.1
  • 31
    • 78049287331 scopus 로고    scopus 로고
    • mTOR signalling and metabolic regulation of T cell differentiation
    • Peter, C., Waldmann, H. and Cobbold, S. P., mTOR signalling and metabolic regulation of T cell differentiation. Curr. Opin. Immunol. 2010. 22: 655-661.
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 655-661
    • Peter, C.1    Waldmann, H.2    Cobbold, S.P.3
  • 32
    • 66949171924 scopus 로고    scopus 로고
    • Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor
    • Miyara, M., Yoshioka, Y., Kitoh, A., Shima, T., Wing, K., Niwa, A., Parizot, C. et al., Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity 2009. 30: 899-911.
    • (2009) Immunity , vol.30 , pp. 899-911
    • Miyara, M.1    Yoshioka, Y.2    Kitoh, A.3    Shima, T.4    Wing, K.5    Niwa, A.6    Parizot, C.7
  • 33
    • 33947162110 scopus 로고    scopus 로고
    • Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
    • Laurence, A., Tato, C. M., Davidson, T. S., Kanno, Y., Chen, Z., Yao, Z., Blank, R. B. et al., Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity 2007. 26: 371-381.
    • (2007) Immunity , vol.26 , pp. 371-381
    • Laurence, A.1    Tato, C.M.2    Davidson, T.S.3    Kanno, Y.4    Chen, Z.5    Yao, Z.6    Blank, R.B.7
  • 34
    • 41549134361 scopus 로고    scopus 로고
    • Th17 cell differentiation: the long and winding road
    • McGeachy, M. J. and Cua, D. J., Th17 cell differentiation: the long and winding road. Immunity 2008. 28: 445-453.
    • (2008) Immunity , vol.28 , pp. 445-453
    • McGeachy, M.J.1    Cua, D.J.2
  • 35
    • 34548317417 scopus 로고    scopus 로고
    • Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome
    • Minegishi, Y., Saito, M., Tsuchiya, S., Tsuge, I., Takada, H., Hara, T., Kawamura, N. et al., Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature 2007. 448: 1058-1062.
    • (2007) Nature , vol.448 , pp. 1058-1062
    • Minegishi, Y.1    Saito, M.2    Tsuchiya, S.3    Tsuge, I.4    Takada, H.5    Hara, T.6    Kawamura, N.7
  • 38
    • 34250351459 scopus 로고    scopus 로고
    • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
    • Deaglio, S., Dwyer, K. M., Gao, W., Friedman, D., Usheva, A., Erat, A., Chen, J.-F. et al., Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J. Exp. Med. 2007. 204: 1257-1265.
    • (2007) J. Exp. Med. , vol.204 , pp. 1257-1265
    • Deaglio, S.1    Dwyer, K.M.2    Gao, W.3    Friedman, D.4    Usheva, A.5    Erat, A.6    Chen, J.-F.7
  • 39
    • 33645778289 scopus 로고    scopus 로고
    • MHC class II expression identifies functionally distinct human regulatory T cells
    • Baecher-Allan, C., Wolf, E. and Hafler, D. A., MHC class II expression identifies functionally distinct human regulatory T cells. J. Immunol. 2006. 176: 4622-4631.
    • (2006) J. Immunol. , vol.176 , pp. 4622-4631
    • Baecher-Allan, C.1    Wolf, E.2    Hafler, D.A.3
  • 41
    • 44649189089 scopus 로고    scopus 로고
    • Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery
    • Ito, T., Hanabuchi, S., Wang, Y.-H., Park, W. R., Arima, K., Bover, L., Qin, F. X.-F. et al., Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery. Immunity 2008. 28: 870-880.
    • (2008) Immunity , vol.28 , pp. 870-880
    • Ito, T.1    Hanabuchi, S.2    Wang, Y.-H.3    Park, W.R.4    Arima, K.5    Bover, L.6    Qin, F.X.-F.7
  • 42
    • 77951638740 scopus 로고    scopus 로고
    • Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells
    • Thornton, A. M., Korty, P. E., Tran, D. Q., Wohlfert, E. A., Murray, P. E., Belkaid, Y. and Shevach, E. M., Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J. Immunol. 2010. 184: 3433-3441.
    • (2010) J. Immunol. , vol.184 , pp. 3433-3441
    • Thornton, A.M.1    Korty, P.E.2    Tran, D.Q.3    Wohlfert, E.A.4    Murray, P.E.5    Belkaid, Y.6    Shevach, E.M.7
  • 43
    • 4444300314 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid
    • van Amelsfort, J. M., Jacobs, K. M., Bijlsma, J. W., Lafeber, F. P. and Taams, L. S., CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid. Arthritis. Rheum. 2004. 50: 2775-2785.
    • (2004) Arthritis. Rheum. , vol.50 , pp. 2775-2785
    • van Amelsfort, J.M.1    Jacobs, K.M.2    Bijlsma, J.W.3    Lafeber, F.P.4    Taams, L.S.5
  • 44
    • 2442618129 scopus 로고    scopus 로고
    • CD4+CD25 bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis
    • de Kleer, I. M., Wedderburn, L. R., Taams, L. S., Patel, A., Varsani, H., Klein, M., de Jager, W. et al., CD4+CD25 bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis. J. Immunol. 2004. 172: 6435-6443.
    • (2004) J. Immunol. , vol.172 , pp. 6435-6443
    • de Kleer, I.M.1    Wedderburn, L.R.2    Taams, L.S.3    Patel, A.4    Varsani, H.5    Klein, M.6    de Jager, W.7
  • 45
    • 17644384896 scopus 로고    scopus 로고
    • CD4+CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis
    • Mottonen, M., Heikkinen, J., Mustonen, L., Isomaki, P., Luukkainen, R. and Lassila, O., CD4+CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis. Clin. Exp. Immunol. 2005. 140: 360-367.
    • (2005) Clin. Exp. Immunol. , vol.140 , pp. 360-367
    • Mottonen, M.1    Heikkinen, J.2    Mustonen, L.3    Isomaki, P.4    Luukkainen, R.5    Lassila, O.6
  • 46
    • 4444300314 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid
    • van Amelsfort, J. M., Jacobs, K. M., Bijlsma, J. W., Lafeber, F. P. and Taams, L. S., CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid. Arthritis Rheum. 2004. 50: 2775-2785.
    • (2004) Arthritis Rheum. , vol.50 , pp. 2775-2785
    • van Amelsfort, J.M.1    Jacobs, K.M.2    Bijlsma, J.W.3    Lafeber, F.P.4    Taams, L.S.5
  • 47
    • 79960912511 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells in systemic sclerosis and other rheumatic diseases
    • Michels-van Amelsfort, J. M., Walter, G. J. and Taams, L. S., CD4+CD25+ regulatory T cells in systemic sclerosis and other rheumatic diseases. Expert Rev. Clin. Immunol. 2011. 7: 499-514.
    • (2011) Expert Rev. Clin. Immunol. , vol.7 , pp. 499-514
    • Michels-van Amelsfort, J.M.1    Walter, G.J.2    Taams, L.S.3
  • 48
    • 80053365569 scopus 로고    scopus 로고
    • Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells
    • Wehrens, E. J., Mijnheer, G., Duurland, C. L., Klein, M., Meerding, J., van Loosdregt, J., de Jager, W. et al., Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells. Blood 2011. 118: 3538-3548.
    • (2011) Blood , vol.118 , pp. 3538-3548
    • Wehrens, E.J.1    Mijnheer, G.2    Duurland, C.L.3    Klein, M.4    Meerding, J.5    van Loosdregt, J.6    de Jager, W.7
  • 49
    • 84874449843 scopus 로고    scopus 로고
    • Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127(low) regulatory T cells
    • Walter, G. J., Evans, H. G., Menon, B., Gullick, N. J., Kirkham, B. W., Cope, A. P., Geissmann, F. et al., Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127(low) regulatory T cells. Arthritis Rheum. 2013. 65: 627-638.
    • (2013) Arthritis Rheum. , vol.65 , pp. 627-638
    • Walter, G.J.1    Evans, H.G.2    Menon, B.3    Gullick, N.J.4    Kirkham, B.W.5    Cope, A.P.6    Geissmann, F.7
  • 50
    • 84866555781 scopus 로고    scopus 로고
    • Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection
    • Klatt, N. R., Estes, J. D., Sun, X., Ortiz, A. M., Barber, J. S., Harris, L. D., Cervasi, B. et al., Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunol. 2012. 5: 646-657.
    • (2012) Mucosal Immunol. , vol.5 , pp. 646-657
    • Klatt, N.R.1    Estes, J.D.2    Sun, X.3    Ortiz, A.M.4    Barber, J.S.5    Harris, L.D.6    Cervasi, B.7
  • 51
    • 43449135305 scopus 로고    scopus 로고
    • TGF-β-induced Foxp3 inhibits Th17 cell differentiation by antagonizing RORγt function
    • Zhou, L. L. J., Chong, M. M., Ivanov, II, Min, R., Victora, G. D., Shen, Y., Du, J. et al., TGF-β-induced Foxp3 inhibits Th17 cell differentiation by antagonizing RORγt function. Nature 2008. 453: 236-240.
    • (2008) Nature , vol.453 , pp. 236-240
    • Zhou, L.L.J.1    Chong, M.M.2    Ivanov, I.I.3    Min, R.4    Victora, G.D.5    Shen, Y.6    Du, J.7
  • 52
    • 0032590079 scopus 로고    scopus 로고
    • Interleukin-1[beta] activates a short STAT-3 isoform in clonal insulin-secreting cells
    • Morton, N. M., de Groot, R. P., Cawthorne, M. A. and Emilsson, V., Interleukin-1[beta] activates a short STAT-3 isoform in clonal insulin-secreting cells. FEBS Lett. 1999. 442: 57-60.
    • (1999) FEBS Lett. , vol.442 , pp. 57-60
    • Morton, N.M.1    de Groot, R.P.2    Cawthorne, M.A.3    Emilsson, V.4
  • 53
    • 32644473626 scopus 로고    scopus 로고
    • Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance
    • Battaglia, M., Stabilini, A., Draghici, E., Gregori, S., Mocchetti, C., Bonifacio, E. and Roncarolo, M. G., Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance. Diabetes 2006. 55: 40-49.
    • (2006) Diabetes , vol.55 , pp. 40-49
    • Battaglia, M.1    Stabilini, A.2    Draghici, E.3    Gregori, S.4    Mocchetti, C.5    Bonifacio, E.6    Roncarolo, M.G.7
  • 55
    • 34447574943 scopus 로고    scopus 로고
    • The maintenance of human CD4 +CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro
    • Yates, J., Rovis, F., Mitchell, P., Afzali, B., Tsang, J. Y.-S., Garin, M., Lechler, R. I. et al., The maintenance of human CD4 +CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro. Int. Immunol. 2007. 19: 785-799.
    • (2007) Int. Immunol. , vol.19 , pp. 785-799
    • Yates, J.1    Rovis, F.2    Mitchell, P.3    Afzali, B.4    Tsang, J.Y.-S.5    Garin, M.6    Lechler, R.I.7
  • 56
    • 79961029064 scopus 로고    scopus 로고
    • Relative resistance of human CD4(+) memory T cells to suppression by CD4(+) CD25(+) regulatory T cells
    • Afzali, B., Mitchell, P. J., Scotta, C., Canavan, J., Edozie, F. C., Fazekasova, H., Lord, G. M. et al., Relative resistance of human CD4(+) memory T cells to suppression by CD4(+) CD25(+) regulatory T cells. Am. J. Transplant. 2011. 11: 1734-1742.
    • (2011) Am. J. Transplant. , vol.11 , pp. 1734-1742
    • Afzali, B.1    Mitchell, P.J.2    Scotta, C.3    Canavan, J.4    Edozie, F.C.5    Fazekasova, H.6    Lord, G.M.7
  • 57
    • 34147092225 scopus 로고    scopus 로고
    • A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses
    • Venken, K., Thewissen, M., Hellings, N., Somers, V., Hensen, K., Rummens, J. L. and Stinissen, P., A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses. J. Immunol. Methods 2007. 322: 1-11.
    • (2007) J. Immunol. Methods , vol.322 , pp. 1-11
    • Venken, K.1    Thewissen, M.2    Hellings, N.3    Somers, V.4    Hensen, K.5    Rummens, J.L.6    Stinissen, P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.