Two lysines in the forkhead domain of Foxp3 are key to T regulatory cell function

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Liu, Yujie ^a   Wang, Liqing ^a   Han, Rongxiang ^a   Beier, Ulf H ^a   Hancock, Wayne W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; FORKHEAD TRANSCRIPTION FACTOR; HISTONE ACETYLTRANSFERASE; INTERLEUKIN 2; LYSINE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR NFAT; BIOLOGICAL MARKER; FOXP3 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; MESSENGER RNA; RAG 1 PROTEIN; RAG-1 PROTEIN; THY 1 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CD4+ CD25+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; DNA BINDING; FLOW CYTOMETRY; GENE EXPRESSION; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE FUNCTION; MICROARRAY ANALYSIS; MOUSE; MUTAGENESIS; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROCESSING; QUANTITATIVE ANALYSIS; REGULATORY T LYMPHOCYTE; ACETYLATION; AMINO ACID SEQUENCE; ANIMAL; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CELL CULTURE; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOUSE MUTANT; MUTATION; PHYSIOLOGY; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY;

ACETYLATION; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, THY-1; AUTOIMMUNITY; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DNA; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; HOMEODOMAIN PROTEINS; HUMANS; INTERLEUKIN-2; LYSINE; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; T-LYMPHOCYTES, REGULATORY;

EID: 84855708785     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029035     Document Type: Article

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